SENS

SEC source: 0001209191-21-041043 · doc4.xml · nonDerivative · entry 1

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,826,903

F1 · kind: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units.

F2 · balance_after: Includes 12,000, 12,000 and 10,548 shares acquired under the Issuer's employee stock purchase plan on January 31, 2020, July 31, 2020 and January 29, 2021, respectively.

SEC source: 0001209191-21-041060 · doc4.xml · nonDerivative · entry 3

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,950,345

F2 · kind: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units.

SEC source: 0001209191-21-041048 · doc4.xml · nonDerivative · entry 1

Horton Kenneth L · CIK 0001552047 · GC & Corp. Development Advisor

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,151,690

F1 · kind: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units.

SEC source: 0001209191-21-041056 · doc4.xml · nonDerivative · entry 1

Tressler Nick B. · CIK 0001794362 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 217,767

F1 · kind: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units.

F2 · balance_after: Includes 2,058, 4,147 and 4,359 shares acquired under the Issuer's employee stock purchase plan on January 31, 2020, July 31, 2020 and January 29, 2021, respectively.

SEC source: 0001209191-21-041045 · doc4.xml · nonDerivative · entry 1

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,151,690

F1 · kind: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units.

SEC source: 0001209191-21-040304 · doc4.xml · derivative · entry 5

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 27,928 shares

Expires 2021-08-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F2 · derivative.exercise_date: Shares are fully vested and exercisable.

SEC source: 0001209191-21-040304 · doc4.xml · nonDerivative · entry 3

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,858,804

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-041060 · doc4.xml · derivative · entry 4

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,599

Underlying: Common Stock · 50,000 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F3 · derivative.exercise_date: Shares are fully vested and exercisable.

SEC source: 0001209191-21-041060 · doc4.xml · nonDerivative · entry 2

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,970,557

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-041060 · doc4.xml · nonDerivative · entry 1

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,020,557

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-040640 · doc4.xml · derivative · entry 3

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 529,084

Underlying: Common Stock · 20,916 shares

Expires 2029-03-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F2 · derivative.exercise_date: One-fourth of the shares vested on March 4, 2020, with the remaining shares vesting in 36 equal installments at the end of the calendar month for each month after March 4, 2020, subject to the reporting person's continuous service with the issuer as of the applicable vesting date.

SEC source: 0001209191-21-040640 · doc4.xml · nonDerivative · entry 2

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,057,876

F1 · kind: The exercise and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-040640 · doc4.xml · nonDerivative · entry 1

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,120,504

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise and sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-039840 · doc4.xml · derivative · entry 6

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 205,599

Underlying: Common Stock · 18,866 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F4 · derivative.exercise_date: Shares are fully vested and exercisable.

SEC source: 0001209191-21-039840 · doc4.xml · nonDerivative · entry 4

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,970,557

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F3 · price: This transaction was executed in multiple trades at prices ranging from $3.50 to $3.54, inclusive. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request by the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transactions were effected as set forth in this footnote.

SEC source: 0001209191-21-039840 · doc4.xml · nonDerivative · entry 3

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,989,423

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-040304 · doc4.xml · derivative · entry 4

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 380,710 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F2 · derivative.exercise_date: Shares are fully vested and exercisable.

SEC source: 0001209191-21-040304 · doc4.xml · nonDerivative · entry 2

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,830,876

F1 · kind: The transactions in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-040304 · doc4.xml · nonDerivative · entry 1

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,211,586

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-039840 · doc4.xml · derivative · entry 5

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 224,465

Underlying: Common Stock · 6,134 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F4 · derivative.exercise_date: Shares are fully vested and exercisable.

SEC source: 0001209191-21-039840 · doc4.xml · nonDerivative · entry 2

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,970,557

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F2 · price: This transaction was executed in multiple trades at prices ranging from $3.50 to $3.505, inclusive. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request by the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transactions were effected as set forth in this footnote.

SEC source: 0001209191-21-039840 · doc4.xml · nonDerivative · entry 1

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,976,691

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-039013 · doc4.xml · nonDerivative · entry 2

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,970,557

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-039013 · doc4.xml · nonDerivative · entry 1

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,995,557

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F2 · balance_after: Includes 2,962, 5,233 and 5,474 shares acquired under the Issuer's employee stock purchase plan on January 31, 2020, July 31, 2020 and January 31, 2021, respectively.

SEC source: 0001209191-21-039015 · doc4.xml · nonDerivative · entry 1

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,099,588

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

SEC source: 0001209191-21-036385 · doc4.xml · nonDerivative · entry 3

DeFalco Stephen P · CIK 0001666964 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,169,853

F3 · kind: Represents the number of shares sold by the Reporting Person to satisfy the Reporting Person's tax obligations resulting from the settlement of vested restricted stock units ("RSUs") on May 25, 2021. The sales were effected pursuant to a "sell-to-cover" arrangement adopted in accordance with Rule 10b5-1 on March 14, 2021.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.00 to $2.02 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-036385 · doc4.xml · nonDerivative · entry 2

DeFalco Stephen P · CIK 0001666964 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,274,780

F3 · kind: Represents the number of shares sold by the Reporting Person to satisfy the Reporting Person's tax obligations resulting from the settlement of vested restricted stock units ("RSUs") on May 25, 2021. The sales were effected pursuant to a "sell-to-cover" arrangement adopted in accordance with Rule 10b5-1 on March 14, 2021.

SEC source: 0001209191-21-036392 · doc4.xml · nonDerivative · entry 3

Panlilio Mirasol · CIK 0001667551 · VP Global Sales and Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,001,433

F2 · shares: Represents a RSU grant. The RSUs vest in eight equal installments with the first installment vesting on June 15, 2021 and the remaining RSUs vesting in six month increments commencing on November 15, 2021, subject to the Reporting Person's continuous service with the Issuer as of the applicable vesting date.

F3 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036388 · doc4.xml · nonDerivative · entry 3

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,830,876

F2 · shares: Represents a RSU grant. The RSUs vest in eight equal installments with the first installment vesting on June 15, 2021 and the remaining RSUs vesting in six month increments commencing on November 15, 2021, subject to the Reporting Person's continuous service with the Issuer as of the applicable vesting date.

F3 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036390 · doc4.xml · nonDerivative · entry 3

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,956,888

F2 · shares: Represents a RSU grant. Represents a RSU grant. The RSUs vest in eight equal installments with the first installment vesting on June 15, 2021 and the remaining RSUs vesting in six month increments commencing on November 15, 2021, subject to the Reporting Person's continuous service with the Issuer as of the applicable vesting date.

F3 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036385 · doc4.xml · nonDerivative · entry 1

DeFalco Stephen P · CIK 0001666964 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,279,084

F1 · shares: Represents an RSU grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the reporting person's continuous service through such vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036387 · doc4.xml · nonDerivative · entry 2

Fiorentino Edward · CIK 0001666972 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 394,127

F3 · shares: Represents an RSU grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the reporting person's continuous service through such vesting date.

F4 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036387 · doc4.xml · nonDerivative · entry 1

Fiorentino Edward · CIK 0001666972 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 333,644

F1 · kind: Represents the number of shares sold by the Reporting Person to satisfy the Reporting Person's tax obligations resulting from the settlement of vested restricted stock units ("RSUs") on May 25, 2021. The sales were effected pursuant to a "sell-to-cover" arrangement adopted in accordance with Rule 10b5-1 on March 14, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.87 to $1.96 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-036393 · doc4.xml · nonDerivative · entry 2

Prince Douglas S · CIK 0001666995 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 292,278

F3 · shares: Represents an RSU grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the reporting person's continuous service through such vesting date.

F4 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036393 · doc4.xml · nonDerivative · entry 1

Prince Douglas S · CIK 0001666995 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 231,795

F1 · kind: Represents the number of shares sold by the Reporting Person to satisfy the Reporting Person's tax obligations resulting from the settlement of vested restricted stock units ("RSUs") on May 25, 2021. The sales were effected pursuant to a "sell-to-cover" arrangement adopted in accordance with Rule 10b5-1 on March 14, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.86 to $1.97 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-036389 · doc4.xml · nonDerivative · entry 2

Horton Kenneth L · CIK 0001552047 · GC & Corp. Development Advisor

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,162,589

F2 · shares: Represents a RSU grant. The RSUs vest in eight equal installments with the first installment vesting on June 15, 2021 and the remaining RSUs vesting in six month increments commencing on November 15, 2021, subject to the Reporting Person's continuous service with the Issuer as of the applicable vesting date.

F3 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036395 · doc4.xml · nonDerivative · entry 1

Tressler Nick B. · CIK 0001794362 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,053

F1 · shares: Represents a restricted stock unit ("RSU") grant. The RSUs vest in eight equal installments with the first installment vesting on June 15, 2021 and the remaining RSUs vesting in six month increments commencing on November 15, 2021, subject to the Reporting Person's continuous service with the Issuer as of the applicable vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036391 · doc4.xml · nonDerivative · entry 3

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,162,215

F2 · shares: Represents a RSU grant. The RSUs vest in eight equal installments with the first installment vesting on June 15, 2021 and the remaining RSUs vesting in six month increments commencing on November 15, 2021, subject to the Reporting Person's continuous service with the Issuer as of the applicable vesting date.

F3 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036386 · doc4.xml · nonDerivative · entry 2

Steven Edelman · CIK 0001683354 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 380,527

F3 · shares: Represents an RSU grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the reporting person's continuous service through such vesting date.

F4 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036386 · doc4.xml · nonDerivative · entry 1

Steven Edelman · CIK 0001683354 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 320,044

F1 · kind: Represents the number of shares sold by the Reporting Person to satisfy the Reporting Person's tax obligations resulting from the settlement of vested restricted stock units ("RSUs") on May 25, 2021. The sales were effected pursuant to a "sell-to-cover" arrangement adopted in accordance with Rule 10b5-1 on March 14, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.87 to $1.97 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-036419 · doc4.xml · nonDerivative · entry 2

ROEDER DOUGLAS A · CIK 0001270735 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,825

F3 · shares: Represents an RSU grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the reporting person's continuous service through such vesting date.

F4 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-036419 · doc4.xml · nonDerivative · entry 1

ROEDER DOUGLAS A · CIK 0001270735 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 125,342

F1 · kind: Represents the number of shares sold by the Reporting Person to satisfy the Reporting Person's tax obligations resulting from the settlement of vested restricted stock units ("RSUs") on May 25, 2021. The sales were effected pursuant to a "sell-to-cover" arrangement adopted in accordance with Rule 10b5-1 on March 14, 2021.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.87 to $1.96 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-068630 · doc4.xml · nonDerivative · entry 1

Raab Anthony R. · CIK 0001827192 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 353,560

F1 · shares: Represents an RSU grant pursuant to the Issuer's non-employee director compensation policy. The RSUs vest in full on the earlier of the one year anniversary of the date of grant or the next annual stockholders meeting, subject to the reporting person's continuous service through such vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001104659-21-070131 · tm2117184d1_4.xml · nonDerivative · entry 1

ROEDER DOUGLAS A · CIK 0001270735 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

F1 · price: This transaction was executed in multiple trades at prices ranging from $2.08 to $2.085, inclusive. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

F2 · ownership.nature: Shares held directly by Delphi BioInvestments VIII, L.P. ("DBI VIII"). The Reporting Person is a managing member of Delphi Management Partners VIII, L.L.C. ("DMP"), the general partner of DBI VIII. As a managing member of DMP, the Reporting Person shares voting and investment power over the securities held by DBI VIII and may be deemed to have indirect beneficial ownership of such shares. The Reporting Person disclaims beneficial ownership of such securities held by DBI VIII, except to the extent of his proportionate pecuniary interest therein.

SEC source: 0001209191-21-034021 · doc4.xml · nonDerivative · entry 1

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,725,135

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the record holder of the securities on March 15, 2021.

F2 · price: This transaction was executed in multiple trades at prices ranging from $1.86 to $2.02, inclusive. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request by the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transactions were effected.

SEC source: 0001209191-21-036392 · doc4.xml · nonDerivative · entry 2

Panlilio Mirasol · CIK 0001667551 · VP Global Sales and Marketing

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 797,132

F1 · shares: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units ("RSUs").

SEC source: 0001209191-21-036388 · doc4.xml · nonDerivative · entry 2

Goodnow Timothy T · CIK 0001667588 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,731,414

F1 · shares: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units ("RSUs").

SEC source: 0001209191-21-036390 · doc4.xml · nonDerivative · entry 2

JAIN Mukul · CIK 0001667593 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,553,663

F1 · shares: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units ("RSUs").

SEC source: 0001209191-21-036389 · doc4.xml · nonDerivative · entry 1

Horton Kenneth L · CIK 0001552047 · GC & Corp. Development Advisor

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 856,138

F1 · shares: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units ("RSUs").

SEC source: 0001209191-21-036391 · doc4.xml · nonDerivative · entry 2

Kaufman Francine · CIK 0001769791 · Director · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 889,097

F1 · shares: Represents shares withheld to satisfy withholding tax obligations upon the vesting of restricted stock units ("RSUs").