INSM

SEC source: 0001628280-23-018684 · wf-form4_168435429831173.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 341,345

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F3 · price: This is a weighted average sales price representing 7,099 shares sold at prices ranging from $18.12 to $18.13 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018673 · wf-form4_168435404211099.xml · nonDerivative · entry 3

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 160,333

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018700 · wf-form4_168435453768194.xml · nonDerivative · entry 2

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,960

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018691 · wf-form4_168435436955097.xml · nonDerivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 95,497

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018696 · wf-form4_168435443742523.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,345

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F3 · price: This is the weighted average sales price representing 475 shares sold at prices ranging from $18.40 to $18.45 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018684 · wf-form4_168435429831173.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 348,444

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018679 · wf-form4_168435416317222.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 117,619

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018681 · wf-form4_168435423354522.xml · nonDerivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 114,906

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F3 · price: This is the weighted average sales price representing 1,718 shares sold at prices ranging from $18.43 to $18.47 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018673 · wf-form4_168435404211099.xml · nonDerivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 162,781

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018700 · wf-form4_168435453768194.xml · nonDerivative · entry 1

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,341

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is the weighted average sales price representing 593 shares sold at prices ranging from $19.29 to $19.30 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018691 · wf-form4_168435436955097.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,714

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018696 · wf-form4_168435443742523.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 78,820

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is the weighted average sales price representing 1,897 shares sold at prices ranging from $19.24 to $19.26 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018684 · wf-form4_168435429831173.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 352,158

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is a weighted average sales price representing 6,048 shares sold at prices ranging from $19.21 to $19.24 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018679 · wf-form4_168435416317222.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,229

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is the weighted average sales price representing 2,210 shares sold at prices ranging from $19.29 to $19.32 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018681 · wf-form4_168435423354522.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 116,624

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is the weighted average sales price representing 2,576 shares sold at prices ranging from $19.27 to $19.28 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018673 · wf-form4_168435404211099.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 164,302

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is the weighted average sales price representing 2,847 shares sold at prices ranging from $19.26 to $19.28 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018666 · wf-form4_168435394565987.xml · nonDerivative · entry 2

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Padonia, LLC

Disclosed balance after: 10,000

F2 · price: This is the weighted average purchase price representing 10,000 shares purchased at prices ranging from $19.22 to $19.34 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares purchased at each price within the price range upon request.

F3 · ownership.nature: The Reporting Person is the managing member of Padonia, LLC.

SEC source: 0001628280-23-018666 · wf-form4_168435394565987.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 298,615

F1 · price: This is the weighted average purchase price representing 10,000 shares purchased at prices ranging from $19.22 to $19.35 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares purchased at each price within the price range upon request.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

Disclosed balance after: 0

Underlying: Common Stock · 83,333 shares

Expires 2023-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · By ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST

Disclosed balance after: 0

Underlying: Common Stock · 83,334 shares

Expires 2023-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · derivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · By ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST

Disclosed balance after: 0

Underlying: Common Stock · 67,257 shares

Expires 2023-05-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · Indirect

Disclosed balance after: 233,924

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · ownership.nature: By ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST, of which the reporting person is a trustee. The reporting person and members of the reporting person's immediate family are the sole beneficiaries of the trust.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · Indirect

Disclosed balance after: 150,590

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · ownership.nature: By ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST, of which the reporting person is a trustee. The reporting person and members of the reporting person's immediate family are the sole beneficiaries of the trust.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Indirect · Indirect

Disclosed balance after: 67,257

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · ownership.nature: By ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST, of which the reporting person is a trustee. The reporting person and members of the reporting person's immediate family are the sole beneficiaries of the trust.

SEC source: 0001628280-23-018209 · wf-form4_168418233227543.xml · nonDerivative · entry 1

SCHAFER CAROL · CIK 0001272181 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,097

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018211 · wf-form4_168418241982699.xml · nonDerivative · entry 2

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 288,615

SEC source: 0001628280-23-018211 · wf-form4_168418241982699.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 290,415

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018207 · wf-form4_168418226315938.xml · nonDerivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,753

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018205 · wf-form4_168418220866282.xml · nonDerivative · entry 1

LEE LEO · CIK 0001740789 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 111,457

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018201 · wf-form4_168418215072198.xml · nonDerivative · entry 1

Desjardins Clarissa · CIK 0001793390 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,787

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018200 · wf-form4_168418208788013.xml · nonDerivative · entry 1

Brennan David R · CIK 0001609305 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,713

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018198 · wf-form4_168418201428060.xml · nonDerivative · entry 1

ANDERSON ELIZABETH M · CIK 0001758247 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,509

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018193 · wf-form4_168418195780663.xml · nonDerivative · entry 1

ALTOMARI ALFRED · CIK 0001285644 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,333

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018183 · wf-form4_168418171156141.xml · derivative · entry 2

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 146,220

Underlying: Common Stock · 146,220 shares

Expires 2033-05-11

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-23-018183 · wf-form4_168418171156141.xml · nonDerivative · entry 1

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,934

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018180 · wf-form4_168418166701360.xml · derivative · entry 2

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,850

Underlying: Common Stock · 121,850 shares

Expires 2033-05-11

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001628280-23-018180 · wf-form4_168418166701360.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,717

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018174 · wf-form4_168418156777258.xml · derivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,850

Underlying: Common Stock · 121,850 shares

Expires 2033-05-11

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-23-018174 · wf-form4_168418156777258.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 98,544

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · derivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 430,140

Underlying: Common Stock · 430,140 shares

Expires 2033-05-11

F4 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-23-018171 · wf-form4_168418150462788.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 358,206

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018167 · wf-form4_168418140031650.xml · derivative · entry 3

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 146,220

Underlying: Common Stock · 146,220 shares

Expires 2033-05-11

F4 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of the grant.

SEC source: 0001628280-23-018167 · wf-form4_168418140031650.xml · nonDerivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,200

F3 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: one third on each anniversary of the date of grant through the third anniversary date of the date of grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018167 · wf-form4_168418140031650.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 104,425

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018160 · wf-form4_168418128865059.xml · derivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 158,410

Underlying: Common Stock · 158,410 shares

Expires 2033-05-11

F4 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-23-018160 · wf-form4_168418128865059.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,439

F3 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: one third on each anniversary of the date of grant through the third anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018160 · wf-form4_168418128865059.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,331

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001628280-23-018152 · wf-form4_168418117556876.xml · derivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 146,220

Underlying: Common Stock · 146,220 shares

Expires 2033-05-11

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-23-018152 · wf-form4_168418117556876.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 167,149

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 11, 2023, for no consideration.

SEC source: 0001140361-23-012309 · form4.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 277,223