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person · Reporting owner

Lewis William

Disclosed activity across 3 companies

Tapewire entity
28834
SEC CIK
0001402051

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
INSMED IncINSM · Entity 3174Director · Chair and CEOJuly 23, 2026July 24, 2026
NewAmsterdam Pharma Co N.V.NAMS · Entity 1826DirectorJanuary 07, 2026January 10, 2026
uniQure N.V.QURE · Entity 4162DirectorJanuary 27, 2017January 31, 2017

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

INSMED Inc

Report date July 23, 2026 · Filed July 24, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect259,058 Ending reported balance After 2026-07-23 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2026-07-23 · Exercise / conversion · Acquired 6,260 · Balance 265,318

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Row 2 · 2026-07-23 · Exercise / conversion · Acquired 4,440 · Balance 269,758

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Row 3 · 2026-07-23 · Sale · Disposed 4,828 · Balance 264,930

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Row 4 · 2026-07-23 · Sale · Disposed 5,872 · Balance 259,058

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $30.46 · Expires 2028-01-04Direct0 Reported balance After 2026-07-23 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-07-23 · Exercise / conversion · Disposed 6,260 · Balance 0

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.16 · Expires 2027-05-17Direct0 Reported balance After 2026-07-23 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-07-23 · Exercise / conversion · Disposed 4,440 · Balance 0

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Common StockSEC Table I · non-derivativeIndirectBy trust233,924 Reported balance Holding disclosure · report date 2026-07-23 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 233,924

Filing footnotes · ownership attribution and instrument terms

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

NewAmsterdam Pharma Co N.V.

Report date January 07, 2026 · Filed January 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeDirect10,360 Reported balance After 2026-01-07 transaction · row 1
1 source row

Row 1 · 2026-01-07 · Grant · Acquired 3,400 · Balance 10,360

F1: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. All of the RSUs will vest on the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

F2: Each RSU was granted on January 7, 2026 for no consideration.

Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.45 · Expires 2036-01-07Direct15,300 Reported balance After 2026-01-07 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-01-07 · Grant · Acquired 15,300 · Balance 15,300

F3: All of the ordinary shares underlying the option will vest on January 2, 2027, the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

Filing footnotes · ownership attribution and instrument terms

F1: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. All of the RSUs will vest on the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

F2: Each RSU was granted on January 7, 2026 for no consideration.

F3: All of the ordinary shares underlying the option will vest on January 2, 2027, the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

uniQure N.V.

Report date January 27, 2017 · Filed January 31, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.37 · Expires 2027-01-27Direct11,000 Reported balance After 2017-01-27 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2017-01-27 · Grant · Acquired 11,000 · Balance 11,000

F1: The Stock Option vests 100% on January 27, 2018.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct16,000 Reported balance After 2017-01-27 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2017-01-27 · Grant · Acquired 11,000 · Balance 16,000

F2: The Restricted Stock Unit vests 100% on January 27, 2018.

F3: Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests.

Filing footnotes · ownership attribution and instrument terms

F1: The Stock Option vests 100% on January 27, 2018.

F2: The Restricted Stock Unit vests 100% on January 27, 2018.

F3: Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
July 23, 2026 Filed Jul 24, 2026 21:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000042 · wk-form4_1784926946.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 23, 2026 Filed Jul 24, 2026 21:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,260 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000042 · wk-form4_1784926946.xml · derivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,260 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 23, 2026 Filed Jul 24, 2026 21:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,872 $106.43 $624,956.96
Disclosure

SEC source: 0001402051-26-000042 · wk-form4_1784926946.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 259,058

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 23, 2026 Filed Jul 24, 2026 21:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,828 $105.62 $509,933.36
Disclosure

SEC source: 0001402051-26-000042 · wk-form4_1784926946.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 264,930

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 23, 2026 Filed Jul 24, 2026 21:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000042 · wk-form4_1784926946.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 269,758

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 23, 2026 Filed Jul 24, 2026 21:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,260 $30.46 $190,679.60
Disclosure

SEC source: 0001402051-26-000042 · wk-form4_1784926946.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 265,318

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,440

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,260

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,359 $118.52 $398,108.68
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 259,058

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 3,359 shares sold at prices ranging from $118.06 to $118.80 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,335 $117.62 $274,642.70
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 262,417

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 2,335 shares sold at prices ranging from $117.05 to $117.96 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,005 $116.55 $583,332.75
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 264,752

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 5,005 shares sold at prices ranging from $116.01 to $117.00 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 269,757

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 09, 2026 Filed Jul 10, 2026 20:02 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000040 · wk-form4_1783713769.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 265,317

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 141 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 8,880 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · derivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,880

Underlying: Common Stock · 8,880 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 12,518 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · derivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,519

Underlying: Common Stock · 12,518 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,292 $106.27 $137,300.84
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 258,917

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 1,292 shares sold at prices ranging from $105.90 to $106.45 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,456 $105.27 $258,543.12
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 260,209

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,456 shares sold at prices ranging from $104.90 to $105.88 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,723 $104.28 $388,234.44
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 262,665

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 3,723 shares sold at prices ranging from $103.87 to $104.75 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,836 $103.10 $189,291.60
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 266,388

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 1,836 shares sold at prices ranging from $102.78 to $103.58 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 12,091 $102.34 $1,237,392.94
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 268,224

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 12,091 shares sold at prices ranging from $101.78 to $102.77 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 8,880 $17.16 $152,380.80
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 280,315

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 20:03 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 12,518 $30.46 $381,298.28
Disclosure

SEC source: 0001402051-26-000038 · wk-form4_1782504217.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 271,435

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 08, 2026 Filed Jun 10, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 6,515 $94.03 $612,605.45
Disclosure

SEC source: 0001402051-26-000035 · wk-form4_1781121933.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 258,917

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:12 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,605 $102.27 $777,763.35
Disclosure

SEC source: 0001402051-26-000032 · wk-form4_1780690345.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 265,432

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,760

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,037

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,975 $106.97 $853,085.75
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 273,037

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 7,975 shares sold at prices ranging from $106.73 to $107.36 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 11,836 $106.39 $1,259,232.04
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 281,012

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 11,836 shares sold at prices ranging from $105.73 to $106.72 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,753 $105.32 $605,905.96
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 292,848

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 5,753 shares sold at prices ranging from $104.73 to $105.71 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 298,601

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
May 18, 2026 Filed May 20, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000030 · wk-form4_1779307577.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 294,161

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
May 13, 2026 Filed May 15, 2026 20:06 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 13,283 $116.18 $1,543,218.94
Disclosure

SEC source: 0001402051-26-000028 · wk-form4_1778875612.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 287,902

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · derivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,200

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · derivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,296

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 381 $139.60 $53,187.60
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,247 $139.09 $173,445.23
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,566

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 1,247 shares sold at prices ranging from $138.52 to $139.43 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,721 $137.86 $375,117.06
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,813

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,721 shares sold at prices ranging from $137.32 to $138.28 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,318 $137.01 $728,619.18
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 305,534

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 5,318 shares sold at prices ranging from $136.32 to $137.30 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 599 $135.18 $80,972.82
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 310,852

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 599 shares sold at prices ranging from $135.06 to $135.50 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 433 $134.18 $58,099.94
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,451

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 433 shares sold at prices ranging from $133.88 to $134.69 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,884

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
May 04, 2026 Filed May 6, 2026 20:11 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000026 · wk-form4_1778098286.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,444

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · derivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,640

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,555

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 825 $145.79 $120,276.75
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 825 shares sold at prices ranging from $145.53 to $146.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,255 $144.66 $326,208.30
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,010

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 2,255 shares sold at prices ranging from $144.40 to $145.20 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,373 $143.81 $772,691.13
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 304,265

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 5,373 shares sold at prices ranging from $143.39 to $144.32 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,246 $142.99 $321,155.54
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 309,638

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 2,246 shares sold at prices ranging from $142.39 to $143.38 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,884

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
April 16, 2026 Filed Apr 17, 2026 20:43 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000024 · wk-form4_1776458613.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,444

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.