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person · Reporting owner

Bonstein Sara

Disclosed activity across 6 companies

Tapewire entity
25936
SEC CIK
0001604019

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Ayala Pharmaceuticals, Inc.ADXS · Entity 93434Chief Financial OfficerMarch 29, 2018April 03, 2018
INSMED IncINSM · Entity 3174Chief Financial OfficerJune 03, 2026June 05, 2026
Latigo Biotherapeutics, Inc.LTGO · Entity 4709DirectorAugust 06, 2026August 07, 2026
ONCOSEC MEDICAL IncONCS · Entity 117092CFO/COOJanuary 16, 2020January 21, 2020
Xilio Therapeutics, Inc.XLO · Entity 7122DirectorJune 11, 2026June 12, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Ayala Pharmaceuticals, Inc.

Report date March 29, 2018 · Filed April 03, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect226,670 Reported balance After 2018-03-29 transaction · row 1
1 source row

Row 1 · 2018-03-29 · Grant · Acquired 1,088 · Balance 226,670

F1: The reporting voluntarily person purchases restricted stock directly from the Company at market price on the last trading day of the month pursuant to an arrangement that was approved by the Compensation Committee of the Company's Board of Directors in a manner that satisfied Exchange Act Rule 16b-3(d). The Company utilizes the net withholding method for each monthly purchase. The reporting person purchased a gross amount of 1,365 shares of which 277 shares were forfeited to pay withholding taxes associated with the stock issuance.

Filing footnotes · ownership attribution and instrument terms

F1: The reporting voluntarily person purchases restricted stock directly from the Company at market price on the last trading day of the month pursuant to an arrangement that was approved by the Compensation Committee of the Company's Board of Directors in a manner that satisfied Exchange Act Rule 16b-3(d). The Company utilizes the net withholding method for each monthly purchase. The reporting person purchased a gross amount of 1,365 shares of which 277 shares were forfeited to pay withholding taxes associated with the stock issuance.

INSMED Inc

Report date June 03, 2026 · Filed June 05, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect69,082 Reported balance After 2026-06-03 transaction · row 1
1 source row

Row 1 · 2026-06-03 · Sale · Disposed 2,404 · Balance 69,082

F1: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Filing footnotes · ownership attribution and instrument terms

F1: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Latigo Biotherapeutics, Inc.

Report date August 06, 2026 · Filed August 07, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Director Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $8.16 · Expires 2036-04-06DirectNot disclosed Reported balance Holding disclosure · report date 2026-08-06 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: The shares subject to this option shall vest in 48 equal monthly installments after April 1, 2026. The shares subject to this option are early exercisable, subject to the Issuer's right of repurchase.

Filing footnotes · ownership attribution and instrument terms

F1: The shares subject to this option shall vest in 48 equal monthly installments after April 1, 2026. The shares subject to this option are early exercisable, subject to the Issuer's right of repurchase.

ONCOSEC MEDICAL Inc

Report date January 16, 2020 · Filed January 21, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect41,389 Reported balance After 2020-01-16 transaction · row 1
1 source row

Row 1 · 2020-01-16 · Sale · Disposed 1,351 · Balance 41,389

F1: In connection with the vesting of 3,906 RSUs on January 16, 2020, a total of 1,351 shares were sold in order to satisfy the reporting person's tax withholding obligations. The reporting person had no discretion with respect to such withholding, which was conducted automatically in accordance with the issuer's corporate policies.

Filing footnotes · ownership attribution and instrument terms

F1: In connection with the vesting of 3,906 RSUs on January 16, 2020, a total of 1,351 shares were sold in order to satisfy the reporting person's tax withholding obligations. The reporting person had no discretion with respect to such withholding, which was conducted automatically in accordance with the issuer's corporate policies.

Xilio Therapeutics, Inc.

Report date June 11, 2026 · Filed June 12, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $7.99 · Expires 2036-06-10Direct5,000 Reported balance After 2026-06-11 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-11 · Grant · Acquired 5,000 · Balance 5,000

F1: The option was granted on June 11, 2026 and will vest as to 100% of the shares underlying the option on the earlier of (i) June 11, 2027 and (ii) the Issuer's next annual meeting of stockholders following the grant date, subject to the Reporting Person's continued service to the Issuer through the vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The option was granted on June 11, 2026 and will vest as to 100% of the shares underlying the option on the earlier of (i) June 11, 2027 and (ii) the Issuer's next annual meeting of stockholders following the grant date, subject to the Reporting Person's continued service to the Issuer through the vesting date.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

scPharmaceuticals Inc.

Report date October 07, 2025 · Filed October 07, 2025

Section 16 reporting ended · disclosed 2025-10-07. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.85 · Expires 2035-06-03Direct0 Reported balance After 2025-10-07 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2025-10-07 · Disposition to issuer · Disposed 30,000 · Balance 0

F1: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.11 · Expires 2034-06-11Direct0 Reported balance After 2025-10-07 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2025-10-07 · Disposition to issuer · Disposed 19,750 · Balance 0

F1: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.53 · Expires 2032-06-14Direct0 Reported balance After 2025-10-07 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2025-10-07 · Disposition to issuer · Disposed 16,300 · Balance 0

F1: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Filing footnotes · ownership attribution and instrument terms

F1: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
June 11, 2026 Filed Jun 12, 2026 20:07 UTC Xilio Therapeutics, Inc. XLO · Entity 7122 GrantStock Option (right to buy) · Derivative 5,000 $0.00 Strike: $7.99 $0.00
Disclosure

SEC source: 0001193125-26-269396 · ownership.xml · derivative · entry 1

Bonstein Sara · CIK 0001604019 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2036-06-10

F1 · derivative.exercise_date: The option was granted on June 11, 2026 and will vest as to 100% of the shares underlying the option on the earlier of (i) June 11, 2027 and (ii) the Issuer's next annual meeting of stockholders following the grant date, subject to the Reporting Person's continued service to the Issuer through the vesting date.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:14 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,404 $102.27 $245,857.08
Disclosure

SEC source: 0001604019-26-000010 · wk-form4_1780690483.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,082

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
May 13, 2026 Filed May 15, 2026 20:08 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 8,272 $116.18 $961,040.96
Disclosure

SEC source: 0001604019-26-000008 · wk-form4_1778875687.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,486

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
February 03, 2026 Filed Feb 4, 2026 21:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 748 $156.34 $116,942.32
Disclosure

SEC source: 0001604019-26-000006 · wk-form4_1770239979.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,758

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 08, 2026 Filed Jan 8, 2026 22:21 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,447 $174.17 $252,023.99
Disclosure

SEC source: 0001604019-26-000004 · wk-form4_1767910881.xml · nonDerivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,506

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 07, 2026 Filed Jan 8, 2026 22:21 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,678 $175.07 $293,767.46
Disclosure

SEC source: 0001604019-26-000004 · wk-form4_1767910881.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 81,953

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 06, 2026 Filed Jan 8, 2026 22:21 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,517 $173.33 $262,941.61
Disclosure

SEC source: 0001604019-26-000004 · wk-form4_1767910881.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,631

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:08 UTC INSMED Inc INSM · Entity 3174 GrantStock Option (right to buy) · Derivative 31,280 $0.00 Strike: $177.12 $0.00
Disclosure

SEC source: 0001604019-26-000002 · wk-form4_1767733720.xml · derivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,280

Underlying: Common Stock · 31,280 shares

Expires 2036-01-02

F4 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:08 UTC INSMED Inc INSM · Entity 3174 GrantCommon Stock 5,645 Not disclosed Not disclosed
Disclosure

SEC source: 0001604019-26-000002 · wk-form4_1767733720.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,148

F3 · shares: Represents RSUs, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest in full on February 1, 2029.

F2 · price: Each RSU was granted on January 2, 2026 for no consideration.

Read SEC document
January 02, 2026 Filed Jan 6, 2026 21:08 UTC INSMED Inc INSM · Entity 3174 GrantCommon Stock 5,998 Not disclosed Not disclosed
Disclosure

SEC source: 0001604019-26-000002 · wk-form4_1767733720.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,503

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on January 2, 2026 for no consideration.

Read SEC document
October 07, 2025 Filed Oct 7, 2025 16:30 UTC scPharmaceuticals Inc. SCPH · Entity 74456 Disposition to issuerStock Option (Right to Buy) · Derivative 16,300 $0.00 Strike: $4.53 $0.00
Disclosure

SEC source: 0001193125-25-233530 · ownership.xml · derivative · entry 3

Bonstein Sara · CIK 0001604019 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 16,300 shares

Expires 2032-06-14

F1 · derivative.exercise_date: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2 · derivative.exercise_date: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Read SEC document
October 07, 2025 Filed Oct 7, 2025 16:30 UTC scPharmaceuticals Inc. SCPH · Entity 74456 Disposition to issuerStock Option (Right to Buy) · Derivative 19,750 $0.00 Strike: $4.11 $0.00
Disclosure

SEC source: 0001193125-25-233530 · ownership.xml · derivative · entry 2

Bonstein Sara · CIK 0001604019 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 19,750 shares

Expires 2034-06-11

F1 · derivative.exercise_date: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2 · derivative.exercise_date: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Read SEC document
October 07, 2025 Filed Oct 7, 2025 16:30 UTC scPharmaceuticals Inc. SCPH · Entity 74456 Disposition to issuerStock Option (Right to Buy) · Derivative 30,000 $0.00 Strike: $3.85 $0.00
Disclosure

SEC source: 0001193125-25-233530 · ownership.xml · derivative · entry 1

Bonstein Sara · CIK 0001604019 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2035-06-03

F1 · derivative.exercise_date: In connection with the terms of an Agreement and Plan of Merger, dated as of August 24, 2025 (the "Merger Agreement"), by and among the Issuer, MannKind Corporation ("Parent") and Seacoast Merger Sub, Inc., a direct wholly owned subsidiary of Parent ("Purchaser"), Purchaser completed a tender offer for shares of the Issuer's common stock ("Common Stock") on October 7, 2025. Pursuant to the terms of the Merger Agreement, immediately prior to the Effective Time, each option to purchase shares of Common Stock (a "Company Option") that was outstanding and unexercised as of immediately prior to the Effective Time and that had an exercise price per share that was less than $5.35, whether or not then vested or exercisable, was cancelled and converted into the right to receive (i) an amount in cash,

F2 · derivative.exercise_date: (Continued from footnote 1) without interest and subject to any applicable withholding taxes, equal to (A) the total number of shares subject to such Company Option immediately prior to such cancellation multiplied by (B) the excess, if any, of (x) $5.35 over (y) the exercise price payable per share underlying such Company Option and (ii) one CVR in respect of each share subject to such Company Option.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 17,100 $0.00 Strike: $34.03 $0.00
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · derivative · entry 10

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,100 shares

Expires 2031-01-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 15,890 $0.00 Strike: $29.13 $0.00
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · derivative · entry 9

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 47,670

Underlying: Common Stock · 15,890 shares

Expires 2034-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 11,455 $0.00 Strike: $28.88 $0.00
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · derivative · entry 8

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 11,455 shares

Expires 2030-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 3,443 $0.00 Strike: $26.46 $0.00
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · derivative · entry 7

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,580

Underlying: Common Stock · 3,443 shares

Expires 2031-05-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 26,310 $103.03 $2,710,719.30
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · nonDerivative · entry 6

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,505

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 26,310 shares sold at prices ranging from $102.77 to $103.37 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 32,090 $102.38 $3,285,374.20
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · nonDerivative · entry 5

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 99,815

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 32,090 shares sold at prices ranging from $101.77 to $102.76 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 17,100 $34.03 $581,913.00
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · nonDerivative · entry 4

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 131,905

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 15,890 $29.13 $462,875.70
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · nonDerivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 114,805

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 11,455 $28.88 $330,820.40
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 98,915

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 21, 2025 Filed Jul 23, 2025 20:35 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 3,443 $26.46 $91,101.78
Disclosure

SEC source: 0001628280-25-035755 · wk-form4_1753302879.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 87,460

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 13,717 $0.00 Strike: $26.46 $0.00
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · derivative · entry 10

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,023

Underlying: Common Stock · 13,717 shares

Expires 2031-05-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 23,565 $0.00 Strike: $26.43 $0.00
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · derivative · entry 9

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,710

Underlying: Common Stock · 23,565 shares

Expires 2032-01-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,362 $0.00 Strike: $24.70 $0.00
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · derivative · entry 8

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,362 shares

Expires 2030-05-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,244 $0.00 Strike: $19.74 $0.00
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · derivative · entry 7

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,880

Underlying: Common Stock · 6,244 shares

Expires 2033-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 22,181 $96.19 $2,133,590.39
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · nonDerivative · entry 6

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,017

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 22,181 shares sold at prices ranging from $96.01 to $96.95 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 35,583 $95.66 $3,403,869.78
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · nonDerivative · entry 5

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,198

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 35,583 shares sold at prices ranging from $95.01 to $96.00 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 13,717 $26.46 $362,951.82
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · nonDerivative · entry 4

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 141,781

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 23,565 $26.43 $622,822.95
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · nonDerivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 128,064

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,362 $24.70 $107,741.40
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 104,499

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
July 07, 2025 Filed Jul 9, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,244 $19.74 $123,256.56
Disclosure

SEC source: 0001604019-25-000003 · wk-form4_1752092291.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 100,137

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 357 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

Read SEC document
June 23, 2025 Filed Jun 25, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 12,636 $0.00 Strike: $19.74 $0.00
Disclosure

SEC source: 0001628280-25-033020 · wk-form4_1750882708.xml · derivative · entry 6

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,124

Underlying: Common Stock · 12,636 shares

Expires 2033-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
June 23, 2025 Filed Jun 25, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 35,253 $0.00 Strike: $18.95 $0.00
Disclosure

SEC source: 0001628280-25-033020 · wk-form4_1750882708.xml · derivative · entry 5

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 99,007

Underlying: Common Stock · 35,253 shares

Expires 2033-05-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
June 23, 2025 Filed Jun 25, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 8,661 $102.15 $884,721.15
Disclosure

SEC source: 0001628280-25-033020 · wk-form4_1750882708.xml · nonDerivative · entry 4

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 93,536

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 8,661 shares sold at prices ranging from $102.04 to $102.61 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 23, 2025 Filed Jun 25, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 49,104 $101.71 $4,994,367.84
Disclosure

SEC source: 0001628280-25-033020 · wk-form4_1750882708.xml · nonDerivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 102,197

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 49,104 shares sold at prices ranging from $101.04 to $102.03 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 23, 2025 Filed Jun 25, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 12,636 $19.74 $249,434.64
Disclosure

SEC source: 0001628280-25-033020 · wk-form4_1750882708.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 151,301

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 23, 2025 Filed Jun 25, 2025 20:18 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 35,253 $18.95 $668,044.35
Disclosure

SEC source: 0001628280-25-033020 · wk-form4_1750882708.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 138,665

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 11, 2025 Filed Jun 12, 2025 20:36 UTC Xilio Therapeutics, Inc. XLO · Entity 7122 GrantStock Option (right to buy) · Derivative 31,000 $0.00 Strike: $0.69 $0.00
Disclosure

SEC source: 0001415889-25-016970 · form4-06122025_080651.xml · derivative · entry 1

Bonstein Sara · CIK 0001604019 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Stock · 31,000 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The option was granted on June 11, 2025 and will vest as to 100% of the shares underlying the option on the earlier of (i) June 11, 2026 and (ii) the Issuer's next annual meeting of stockholders following the grant date, subject to the Reporting Person's continued service to the Issuer through the vesting date.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 23,740 $0.00 Strike: $17.07 $0.00
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · derivative · entry 10

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,610

Underlying: Common Stock · 23,740 shares

Expires 2032-05-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 24,150 $0.00 Strike: $18.95 $0.00
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · derivative · entry 9

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 134,260

Underlying: Common Stock · 24,150 shares

Expires 2033-05-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 100 $91.66 $9,166.00
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 8

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 103,412

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 6,328 $90.93 $575,405.04
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 7

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 103,512

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 6,328 shares sold at prices ranging from $90.55 to $91.44 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 15,825 $89.85 $1,421,876.25
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 6

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 109,840

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 15,825 shares sold at prices ranging from $89.54 to $90.53 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 20,926 $88.99 $1,862,204.74
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 5

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,665

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 20,926 shares sold at prices ranging from $88.54 to $89.53 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,310 $88.29 $645,399.90
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 4

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 146,591

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 7,310 shares sold at prices ranging from $87.54 to $88.53 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,277 $87.12 $633,972.24
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 3

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 153,901

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 7,277 shares sold at prices ranging from $86.43 to $87.39 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 23,740 $17.07 $405,241.80
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 161,178

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
June 10, 2025 Filed Jun 12, 2025 20:19 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 24,150 $18.95 $457,642.50
Disclosure

SEC source: 0001628280-25-030961 · wk-form4_1749759395.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 137,438

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.