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person · Reporting owner

MARAGANORE JOHN

Disclosed activity across 9 companies

Tapewire entity
32216
SEC CIK
0001180432

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AGIOS PHARMACEUTICALS, INC.AGIO · Entity 4499DirectorDecember 31, 2022February 03, 2023
ALNYLAM PHARMACEUTICALS, INC.ALNY · Entity 3132Director · Chief Executive OfficerDecember 21, 2021December 23, 2021
Beam Therapeutics Inc.BEAM · Entity 4227DirectorJune 03, 2026June 05, 2026
Hemab Therapeutics Holdings, Inc.COAG · Entity 4476DirectorJanuary 29, 2026May 04, 2026
Kymera Therapeutics, Inc.KYMR · Entity 3545DirectorJune 24, 2026June 25, 2026
PROKIDNEY CORP.PROK · Entity 5181DirectorJune 29, 2023July 03, 2023
Rapport Therapeutics, Inc.RAPP · Entity 4394DirectorJune 10, 2026June 10, 2026
TAKEDA PHARMACEUTICAL CO LTDTAK · Entity 2662DirectorJuly 01, 2026July 06, 2026
bluebird bio, Inc.BLUE · Entity 78923DirectorSeptember 14, 2017September 18, 2017

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AGIOS PHARMACEUTICALS, INC.

Report date December 31, 2022 · Filed February 03, 2023

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common stockSEC Table I · non-derivativeDirect28,528 Reported balance After 2022-09-20 transaction · row 1
1 source row

Row 1 · 2022-09-20 · Gift · Disposed 1,500 · Balance 28,528

F1: This disposition reflects a bona fide gift of 1,500 shares to charity.

Filing footnotes · ownership attribution and instrument terms

F1: This disposition reflects a bona fide gift of 1,500 shares to charity.

ALNYLAM PHARMACEUTICALS, INC.

Report date December 21, 2021 · Filed December 23, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect227,663 Ending reported balance After 2021-12-22 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2021-12-21 · Grant · Acquired 14,167 · Balance 234,299

F1: On February 28, 2019, the reporting person was granted performance-based restricted stock units (PSU) in connection with the 2018 year-end compensation review. One third of the PSU award vests upon the achievement of each of three specific clinical development, regulatory or commercial events. The People, Culture and Compensation Committee of the Board determined that the final performance criterion was met and the final one-third of the PSU award vested as of December 21, 2021.

Row 2 · 2021-12-22 · Tax withholding · Disposed 6,315 · Balance 227,984

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Row 3 · 2021-12-22 · Tax withholding · Disposed 2 · Balance 227,982

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Row 4 · 2021-12-22 · Tax withholding · Disposed 319 · Balance 227,663

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Common StockSEC Table I · non-derivativeIndirectby Managed Account3,133 Reported balance Holding disclosure · report date 2021-12-21 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 3,133

F3: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Filing footnotes · ownership attribution and instrument terms

F1: On February 28, 2019, the reporting person was granted performance-based restricted stock units (PSU) in connection with the 2018 year-end compensation review. One third of the PSU award vests upon the achievement of each of three specific clinical development, regulatory or commercial events. The People, Culture and Compensation Committee of the Board determined that the final performance criterion was met and the final one-third of the PSU award vested as of December 21, 2021.

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

F3: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Beam Therapeutics Inc.

Report date June 03, 2026 · Filed June 05, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $29.55 · Expires 2036-06-03Direct19,676 Reported balance After 2026-06-03 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-03 · Grant · Acquired 19,676 · Balance 19,676

F1: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Hemab Therapeutics Holdings, Inc.

Report date January 29, 2026 · Filed May 04, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect35,948 Ending reported balance After 2026-05-04 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2026-05-04 · Conversion · Acquired 17,974 · Balance 17,974

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Row 2 · 2026-05-04 · Conversion · Acquired 17,974 · Balance 35,948

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Warrants (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.00 · Expires 2036-01-28Direct107,338 Reported balance After 2026-01-29 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-01-29 · Grant · Acquired 107,338 · Balance 107,338

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Series B Preferred StockSEC Table II · derivative / convertible securityDirect0 Reported balance After 2026-05-04 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-05-04 · Conversion · Disposed 817 · Balance 0

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Series C Preferred StockSEC Table II · derivative / convertible securityDirect0 Reported balance After 2026-05-04 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-05-04 · Conversion · Disposed 817 · Balance 0

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Filing footnotes · ownership attribution and instrument terms

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Kymera Therapeutics, Inc.

Report date June 24, 2026 · Filed June 25, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $99.87 · Expires 2036-06-23Direct6,068 Reported balance After 2026-06-24 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-24 · Grant · Acquired 6,068 · Balance 6,068

F1: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.

PROKIDNEY CORP.

Report date June 29, 2023 · Filed July 03, 2023

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Director stock option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $10.56 · Expires 2033-06-29Direct48,128 Reported balance After 2023-06-29 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2023-06-29 · Grant · Acquired 48,128 · Balance 48,128

F1: These options were granted under the Issuer's non-employee director compensation policy.

F2: The options will vest in full on the sooner of the one-year anniversary of the date of grant or the date of Company's next annual general shareholder meeting.

Filing footnotes · ownership attribution and instrument terms

F1: These options were granted under the Issuer's non-employee director compensation policy.

F2: The options will vest in full on the sooner of the one-year anniversary of the date of grant or the date of Company's next annual general shareholder meeting.

Rapport Therapeutics, Inc.

Report date June 10, 2026 · Filed June 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.21 · Expires 2036-06-10Direct15,200 Reported balance After 2026-06-10 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-10 · Grant · Acquired 15,200 · Balance 15,200

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

TAKEDA PHARMACEUTICAL CO LTD

Report date July 01, 2026 · Filed July 06, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeDirect10,400 Reported balance After 2026-07-01 transaction · row 1 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 1 · 2026-07-01 · Grant · Acquired 3,800 · Balance 10,400

F1: Represents an award of restricted stock units (RSU). Each RSU represents a contingent right to receive one Ordinary Share, which will be converted into an equivalent number of American Depositary Shares following vest. The RSUs vest on June 1, 2029.

F2: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

Tax Obligation AwardSEC Table II · derivative / convertible security · Expires 2026-06-01Direct0 Reported balance After 2026-07-10 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-07-10 · Disposition to issuer · Disposed 1,152 · Balance 0

F3: Each Tax Obligation Award was the economic equivalent of one Ordinary Share that, upon vest, was converted into to a cash payment primarily to cover tax obligations. Any remaining proceeds from the disposition of the associated Ordinary Shares will be delivered to the reporting person on July 10.

F4: The price reported in Column 8 is a weighted average price denominated in Yen. These shares were sold in transactions at prices ranging from JPY 4,883 to JPY 5,045, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Tax Obligation AwardSEC Table II · derivative / convertible security · Expires 2029-06-01Direct1,319 Reported balance After 2026-07-01 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-07-01 · Grant · Acquired 1,319 · Balance 1,319

F5: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

American Depositary SharesSEC Table I · non-derivativeDirect13,800 Reported balance Holding disclosure · report date 2026-07-01 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 13,800

F2: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

Filing footnotes · ownership attribution and instrument terms

F1: Represents an award of restricted stock units (RSU). Each RSU represents a contingent right to receive one Ordinary Share, which will be converted into an equivalent number of American Depositary Shares following vest. The RSUs vest on June 1, 2029.

F2: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

F3: Each Tax Obligation Award was the economic equivalent of one Ordinary Share that, upon vest, was converted into to a cash payment primarily to cover tax obligations. Any remaining proceeds from the disposition of the associated Ordinary Shares will be delivered to the reporting person on July 10.

F4: The price reported in Column 8 is a weighted average price denominated in Yen. These shares were sold in transactions at prices ranging from JPY 4,883 to JPY 5,045, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F5: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

bluebird bio, Inc.

Report date September 14, 2017 · Filed September 18, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect5,843 Ending reported balance After 2017-09-14 transaction · row 3
3 source rows · reconciled sequence

Row 1 · 2017-09-14 · Exercise / conversion · Acquired 18,868 · Balance 24,711

Row 2 · 2017-09-14 · Sale · Disposed 18,268 · Balance 6,443

F1: The range in prices for the transaction reported on this line was $130.80 to $131.75. The average weighted price was $131.1935. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Row 3 · 2017-09-14 · Sale · Disposed 600 · Balance 5,843

F2: The range in prices for the transaction reported on this line was $131.80 to $131.90. The average weighted price was $131.8167. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.09 · Expires 2022-01-08Direct0 Reported balance After 2017-09-14 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2017-09-14 · Exercise / conversion · Acquired 18,868 · Balance 0

F3: This option vests in 48 equal monthly installments, commencing on April 1, 2011.

Filing footnotes · ownership attribution and instrument terms

F1: The range in prices for the transaction reported on this line was $130.80 to $131.75. The average weighted price was $131.1935. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

F2: The range in prices for the transaction reported on this line was $131.80 to $131.90. The average weighted price was $131.8167. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

F3: This option vests in 48 equal monthly installments, commencing on April 1, 2011.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
September 27, 2018 Filed Sep 28, 2018 20:56 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 16,250 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-18-000073 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,750

Underlying: Common Stock · 16,250 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective September 27, 2018, the compensation committee of the Company determined the third performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
September 12, 2018 Filed Sep 13, 2018 20:01 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 SaleCommon stock 14,162 $71.74 $1,015,981.88
Disclosure

SEC source: 0001209191-18-050824 · doc4.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,047

F3 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $71.70 to $72.17. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
September 12, 2018 Filed Nov 6, 2018 21:12 UTC Amendment AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 SaleCommon stock 0 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-18-057372 · doc4a.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,209

F1 · kind: On September 13, 2018, the reporting person filed a Form 4 reporting the sale of 14,162 shares of common stock. The previously reported transaction was subsequently broken and unwound by the broker and, therefore, did not in fact occur for the reporting person's account. As of September 12, 2018, the reporting person beneficially owned 36,209 shares of common stock of Agios Pharmaceuticals, Inc.

F1 · price: On September 13, 2018, the reporting person filed a Form 4 reporting the sale of 14,162 shares of common stock. The previously reported transaction was subsequently broken and unwound by the broker and, therefore, did not in fact occur for the reporting person's account. As of September 12, 2018, the reporting person beneficially owned 36,209 shares of common stock of Agios Pharmaceuticals, Inc.

Read SEC document
September 11, 2018 Filed Sep 13, 2018 20:01 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 SaleCommon stock 2,400 $73.82 $177,168.00
Disclosure

SEC source: 0001209191-18-050824 · doc4.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,209

F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $73.33 to $74.25. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
September 11, 2018 Filed Sep 13, 2018 20:01 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 SaleCommon stock 11,155 $72.52 $808,960.60
Disclosure

SEC source: 0001209191-18-050824 · doc4.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,609

F1 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $72.27 to $72.89. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

Read SEC document
August 21, 2018 Filed Aug 23, 2018 20:15 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 16,250 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-18-000062 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Common Stock · 16,250 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development or commercial events, as approved by our compensation committee. Effective August 21, 2018, the compensation committee of the Company determined the second performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
August 10, 2018 Filed Aug 14, 2018 22:33 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Based Stock Option 2014 (right to buy) · Derivative 25,000 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001325812-18-000029 · primary_doc.xml · derivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 25,000 shares

Expires 2024-12-17

F2 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective August 10, 2018, the compensation committee of the Company determined the final performance criteria had been met and the option vested as to the final third of the award.

Read SEC document
August 10, 2018 Filed Aug 14, 2018 22:33 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Based Stock Option 2013 (right to buy) · Derivative 25,000 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001325812-18-000029 · primary_doc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 15,000 shares

Expires 2023-12-18

F1 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective August 10, 2018, the compensation committee of the Company determined the final performance criteria had been met and the option will vest as to the final third of the award.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 50,000 $0.00 Strike: $21.35 $0.00
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · derivative · entry 9

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,636

Underlying: Common Stock · 50,000 shares

Expires 2018-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

F8 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 1,400 $106.25 $148,750.00
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,297

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

F6 · price: Sale prices ranged from $106.18 to $106.33.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 34,995 $105.83 $3,703,520.85
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,697

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

F5 · price: Sale prices ranged from $105.17 to $106.13.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 7,758 $104.83 $813,271.14
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 187,692

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

F4 · price: Sale prices ranged from $104.17 to $105.15.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 3,847 $103.69 $398,895.43
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 195,450

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

F3 · price: Sale prices ranged from $103.10 to $104.04.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 2,000 $102.51 $205,020.00
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 199,297

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

F2 · price: Sale prices ranged from $101.99 to $102.94.

Read SEC document
July 25, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 50,000 $21.35 $1,067,500.00
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 201,297

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 16, 2018. The 50,000 options exercised and sold by the reporting person were due to expire on December 8, 2018.

Read SEC document
July 10, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 31 $0.00 $0.00
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 8

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 3,021

F7 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F7 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F7 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
May 31, 2018 Filed Jun 4, 2018 20:26 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 GrantRestricted stock units · Derivative 1,400 $0.00 $0.00
Disclosure

SEC source: 0001209191-18-035082 · doc4.xml · derivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,400

Underlying: Common stock · 1,400 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on May 31, 2018. The shares underlying the stock units will vest in full on May 31, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on May 31, 2018. The shares underlying the stock units will vest in full on May 31, 2019. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
May 31, 2018 Filed Jun 4, 2018 20:26 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 GrantStock option (right to buy) · Derivative 5,700 $0.00 Strike: $93.50 $0.00
Disclosure

SEC source: 0001209191-18-035082 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,700

Underlying: Common stock · 5,700 shares

Expires 2028-05-30

F1 · derivative.exercise_date: This option was granted on May 31, 2018. The shares underlying this option vest as to 100% of the underlying shares on May 31, 2019.

Read SEC document
April 16, 2018 Filed Jul 27, 2018 20:07 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 OtherCommon Stock 30 $0.00 $0.00
Disclosure

SEC source: 0001735276-18-000039 · edgardoc.xml · nonDerivative · entry 7

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,990

F7 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F7 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F7 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
March 01, 2018 Filed Mar 5, 2018 22:49 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantStock Option (right to buy) · Derivative 52,500 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000012 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,500

Underlying: Common Stock · 52,500 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 52,500 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

Read SEC document
December 20, 2017 Filed Dec 21, 2017 21:36 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Based Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001325812-17-000035 · primary_doc.xml · derivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,250

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F2 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. Effective December 20, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
December 19, 2017 Filed Dec 21, 2017 21:36 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 1,587 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001325812-17-000035 · primary_doc.xml · derivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,413

Underlying: Common Stock · 1,587 shares

Expires 2023-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter

Read SEC document
December 19, 2017 Filed Dec 21, 2017 21:36 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 1,587 $63.00 $99,981.00
Disclosure

SEC source: 0001325812-17-000035 · primary_doc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 151,297

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (Right to Buy) · Derivative 73,415 $0.00 Strike: $31.39 $0.00
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · derivative · entry 7

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 73,415 shares

Expires 2017-12-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F7 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

F1 · derivative.expiration_date: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 2,683 $132.73 $356,114.59
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,710

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F5 · price: Sale prices ranged from $132.38 to $133.34.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 20,433 $131.82 $2,693,478.06
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,393

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F4 · price: Sale prices ranged from $131.38 to $132.36.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 25,036 $130.88 $3,276,711.68
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,826

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F3 · price: Sale prices ranged from $130.38 to $131.37.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 25,263 $129.97 $3,283,432.11
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 197,862

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F2 · price: Sale prices ranged from $129.39 to $130.35.

Read SEC document
November 22, 2017 Filed Nov 24, 2017 23:55 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 73,415 $31.39 $2,304,496.85
Disclosure

SEC source: 0001553878-17-000069 · primary_doc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,125

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 73,415 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (Right to Buy) · Derivative 74,000 $0.00 Strike: $31.39 $0.00
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · derivative · entry 9

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,415

Underlying: Common Stock · 74,000 shares

Expires 2017-12-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F9 · derivative.exercise_date: The stock option vested as to 25% of the shares on the first anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

F1 · derivative.expiration_date: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 600 $130.22 $78,130.80
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 7

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,710

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F7 · price: Sale prices ranged from $130.15 to $130.41.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 4,850 $129.57 $628,414.50
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,310

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F6 · price: Sale prices ranged from $129.11 to $130.00.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 10,571 $128.48 $1,358,204.36
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,160

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F5 · price: Sale prices ranged from $128.09 to $129.08.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 7,120 $127.54 $908,084.80
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 165,731

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F4 · price: Sale prices ranged from $127.08 to $128.06.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 28,399 $126.60 $3,595,398.60
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,851

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F3 · price: Sale prices ranged from $126.08 to $127.05.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 22,460 $125.54 $2,819,718.24
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 201,250

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

F2 · price: Sale prices ranged from $125.07 to $126.05.

Read SEC document
November 15, 2017 Filed Nov 17, 2017 22:35 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 74,000 $31.39 $2,322,860.00
Disclosure

SEC source: 0001553878-17-000068 · primary_doc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 223,710

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 13, 2017. The 74,000 options exercised and sold by the reporting person were due to expire on December 12, 2017.

Read SEC document
November 06, 2017 Filed Nov 8, 2017 22:25 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2015 (right to buy) · Derivative 16,250 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001553878-17-000065 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,250

Underlying: Common Stock · 16,250 shares

Expires 2025-12-18

F1 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option will vest upon the achievement of each of four specific clinical development and regulatory events, as approved by our compensation committee. Effective November 6, 2017, the compensation committee of the Company determined the first performance criterion had been met and the option vested as to one-quarter of the shares.

Read SEC document
September 20, 2017 Filed Sep 22, 2017 21:08 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2013 (right to buy) · Derivative 25,000 $0.00 Strike: $63.00 $0.00
Disclosure

SEC source: 0001553878-17-000051 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2023-12-17

F1 · kind: On December 18, 2013, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective September 20, 2017, the compensation committee of the company determined the second performance criteria had been met and the option will vest as to one-third of the shares.

Read SEC document
September 14, 2017 Filed Sep 18, 2017 20:09 UTC bluebird bio, Inc. BLUE · Entity 78923 Exercise / conversionStock Option (right to buy) · Derivative 18,868 $0.00 Strike: $2.09 $0.00
Disclosure

SEC source: 0001209191-17-053149 · doc4.xml · derivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: CommonStock · 18,868 shares

Expires 2022-01-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vests in 48 equal monthly installments, commencing on April 1, 2011.

Read SEC document
September 14, 2017 Filed Sep 18, 2017 20:09 UTC bluebird bio, Inc. BLUE · Entity 78923 SaleCommon Stock 600 $131.82 $79,090.02
Disclosure

SEC source: 0001209191-17-053149 · doc4.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,843

F2 · price: The range in prices for the transaction reported on this line was $131.80 to $131.90. The average weighted price was $131.8167. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
September 14, 2017 Filed Sep 18, 2017 20:09 UTC bluebird bio, Inc. BLUE · Entity 78923 SaleCommon Stock 18,268 $131.19 $2,396,642.86
Disclosure

SEC source: 0001209191-17-053149 · doc4.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,443

F1 · price: The range in prices for the transaction reported on this line was $130.80 to $131.75. The average weighted price was $131.1935. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
September 14, 2017 Filed Sep 18, 2017 20:09 UTC bluebird bio, Inc. BLUE · Entity 78923 Exercise / conversionCommon Stock 18,868 $2.09 $39,434.12
Disclosure

SEC source: 0001209191-17-053149 · doc4.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,711

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 24, 2017 Filed Aug 28, 2017 20:17 UTC bluebird bio, Inc. BLUE · Entity 78923 Exercise / conversionStock Option (right to buy) · Derivative 13,839 $0.00 Strike: $2.09 $0.00
Disclosure

SEC source: 0001209191-17-050378 · doc4.xml · derivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,868

Underlying: CommonStock · 13,839 shares

Expires 2022-01-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This option vests in 48 equal monthly installments, commencing on April 1, 2011.

Read SEC document
August 24, 2017 Filed Aug 28, 2017 20:17 UTC bluebird bio, Inc. BLUE · Entity 78923 SaleCommon Stock 6,385 $96.32 $615,019.16
Disclosure

SEC source: 0001209191-17-050378 · doc4.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,597

F2 · price: The range in prices for the transaction reported on this line was $95.65 to $96.60. The average weighted price was $96.3225. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
August 24, 2017 Filed Aug 28, 2017 20:17 UTC bluebird bio, Inc. BLUE · Entity 78923 SaleCommon Stock 4,700 $95.13 $447,088.91
Disclosure

SEC source: 0001209191-17-050378 · doc4.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,982

F1 · price: The range in prices for the transaction reported on this line was $94.65 to $95.60. The average weighted price was $95.1253. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
August 24, 2017 Filed Aug 28, 2017 20:17 UTC bluebird bio, Inc. BLUE · Entity 78923 Exercise / conversionCommon Stock 13,839 $2.09 $28,923.51
Disclosure

SEC source: 0001209191-17-050378 · doc4.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,682

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 02, 2017 Filed Aug 28, 2017 20:17 UTC bluebird bio, Inc. BLUE · Entity 78923 SaleCommon Stock 2,754 $96.74 $266,424.99
Disclosure

SEC source: 0001209191-17-050378 · doc4.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,843

F3 · price: The range in prices for the transaction reported on this line was $96.65 to $96.95. The average weighted price was $96.7411. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

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July 07, 2017 Filed Jul 11, 2017 20:34 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantPerformance Stock Option 2014 (right to buy) · Derivative 25,000 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001553878-17-000044 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 25,000 shares

Expires 2024-12-17

F1 · kind: On December 17, 2014, the reporting person was granted a performance based stock option to purchase shares of ALNY Common Stock. One-third of the shares subject to the option will vest upon the achievement of each of three specific clinical development and regulatory events, as approved by our compensation committee. Effective July 7, 2017, the compensation committee of the Company determined the second performance criteria had been met and the option vested as to one-third of the shares.

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June 13, 2017 Filed Jun 15, 2017 21:05 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 GrantStock option (right to buy) · Derivative 8,000 $0.00 Strike: $50.73 $0.00
Disclosure

SEC source: 0001209191-17-040193 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Common stock · 8,000 shares

Expires 2027-06-12

F1 · derivative.exercise_date: This option was granted on June 13, 2017. The shares underlying this option vest as to 100% of the underlying shares on June 13, 2018.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.