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Nasdaq · USD

AGIO

AGIOS PHARMACEUTICALS, INC.

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Tapewire entity
4499
SEC CIK
0001439222
Parsed reports
520

Last 12 months

Inside the activity.

0 purchase rows · 39 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202502
Dec 202506
Jan 202601
Feb 202600
Mar 2026021
Apr 202607
May 202600
Jun 202600
Jul 202601
Aug 202601
Sep 202600
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
August 04, 2026 Filed Aug 6, 2026 20:13 UTC
Gheuens SarahChief Medical Officer
SaleCommon stock 30,000 $30.48 $914,400.00
Disclosure

SEC source: 0001439222-26-000120 · wk-form4_1786047196.xml · nonDerivative · entry 1

Gheuens Sarah · CIK 0001881190 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,645

F1 · kind: This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The price reported is the weighted average of the shares sold. The shares were sold at varying prices in the range of $30.25 to $30.88. The reporting person undertakes, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.

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July 08, 2026 Filed Jul 10, 2026 16:18 UTC Exercise / conversionRestricted stock units · Derivative 1,447 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000112 · wk-form4_1783714678.xml · derivative · entry 2

Backstrom Jay T. · CIK 0001796398 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,894

Underlying: Common stock · 1,447 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on July 8, 2025. Beginning on July 8, 2026, the shares underlying the restricted stock units will vest in three equal annual installments.

F2 · derivative.expiration_date: The restricted stock units were granted on July 8, 2025. Beginning on July 8, 2026, the shares underlying the restricted stock units will vest in three equal annual installments.

Read SEC document
July 08, 2026 Filed Jul 10, 2026 16:18 UTC GrantCommon stock 1,447 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000112 · wk-form4_1783714678.xml · nonDerivative · entry 1

Backstrom Jay T. · CIK 0001796398 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,447

Read SEC document
July 01, 2026 Filed Jul 2, 2026 20:03 UTC
Gheuens SarahChief Medical Officer
Exercise / conversionRestricted stock units · Derivative 8,375 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000110 · wk-form4_1783022592.xml · derivative · entry 3

Gheuens Sarah · CIK 0001881190 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 8,375 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on July 1, 2023. Beginning on July 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments.

F3 · derivative.expiration_date: The restricted stock units were granted on July 1, 2023. Beginning on July 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 20:03 UTC
Gheuens SarahChief Medical Officer
SaleCommon stock 4,007 $37.56 $150,502.92
Disclosure

SEC source: 0001439222-26-000110 · wk-form4_1783022592.xml · nonDerivative · entry 2

Gheuens Sarah · CIK 0001881190 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,645

F1 · kind: Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated July 1, 2023.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 20:03 UTC
Gheuens SarahChief Medical Officer
Exercise / conversionCommon stock 8,375 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000110 · wk-form4_1783022592.xml · nonDerivative · entry 1

Gheuens Sarah · CIK 0001881190 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 88,652

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:13 UTC
Milanova TsvetaChief Commercial Officer
GrantRestricted stock units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000081 · wk-form4_1782249197.xml · derivative · entry 2

Milanova Tsveta · CIK 0001957180 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:13 UTC
Milanova TsvetaChief Commercial Officer
Exercise / conversionPerformance share units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000081 · wk-form4_1782249197.xml · derivative · entry 1

Milanova Tsveta · CIK 0001957180 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:15 UTC
Gheuens SarahChief Medical Officer
GrantRestricted stock units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000085 · wk-form4_1782249348.xml · derivative · entry 2

Gheuens Sarah · CIK 0001881190 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:15 UTC
Gheuens SarahChief Medical Officer
Exercise / conversionPerformance share units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000085 · wk-form4_1782249348.xml · derivative · entry 1

Gheuens Sarah · CIK 0001881190 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000097 · wk-form4_1782249676.xml · derivative · entry 4

Owen Adams Catherine · CIK 0001816838 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000097 · wk-form4_1782249676.xml · derivative · entry 3

Owen Adams Catherine · CIK 0001816838 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000097 · wk-form4_1782249676.xml · derivative · entry 2

Owen Adams Catherine · CIK 0001816838 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000097 · wk-form4_1782249676.xml · nonDerivative · entry 1

Owen Adams Catherine · CIK 0001816838 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,865

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:25 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000107 · wk-form4_1782249916.xml · derivative · entry 4

Ballal Rahul D. · CIK 0001805097 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:25 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000107 · wk-form4_1782249916.xml · derivative · entry 3

Ballal Rahul D. · CIK 0001805097 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:25 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000107 · wk-form4_1782249916.xml · derivative · entry 2

Ballal Rahul D. · CIK 0001805097 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:25 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000107 · wk-form4_1782249916.xml · nonDerivative · entry 1

Ballal Rahul D. · CIK 0001805097 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,230

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:12 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000079 · wk-form4_1782249139.xml · derivative · entry 2

Backstrom Jay T. · CIK 0001796398 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F3 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:12 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000079 · wk-form4_1782249139.xml · derivative · entry 1

Backstrom Jay T. · CIK 0001796398 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:24 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000105 · wk-form4_1782249875.xml · derivative · entry 4

CAPELLO JEFFREY D · CIK 0001224108 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:24 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000105 · wk-form4_1782249875.xml · derivative · entry 3

CAPELLO JEFFREY D · CIK 0001224108 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:24 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000105 · wk-form4_1782249875.xml · derivative · entry 2

CAPELLO JEFFREY D · CIK 0001224108 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:24 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000105 · wk-form4_1782249875.xml · nonDerivative · entry 1

CAPELLO JEFFREY D · CIK 0001224108 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,865

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:23 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000103 · wk-form4_1782249832.xml · derivative · entry 5

Foster-Cheek Kaye I · CIK 0001312622 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:23 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000103 · wk-form4_1782249832.xml · derivative · entry 4

Foster-Cheek Kaye I · CIK 0001312622 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:23 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000103 · wk-form4_1782249832.xml · derivative · entry 3

Foster-Cheek Kaye I · CIK 0001312622 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:23 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000103 · wk-form4_1782249832.xml · nonDerivative · entry 1

Foster-Cheek Kaye I · CIK 0001312622 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,284

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC
Ho MaykinDirector
GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000099 · wk-form4_1782249717.xml · derivative · entry 4

Ho Maykin · CIK 0001646395 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC
Ho MaykinDirector
GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000099 · wk-form4_1782249717.xml · derivative · entry 3

Ho Maykin · CIK 0001646395 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

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June 18, 2026 Filed Jun 23, 2026 21:21 UTC
Ho MaykinDirector
Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000099 · wk-form4_1782249717.xml · derivative · entry 2

Ho Maykin · CIK 0001646395 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:21 UTC
Ho MaykinDirector
Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000099 · wk-form4_1782249717.xml · nonDerivative · entry 1

Ho Maykin · CIK 0001646395 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,848

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:22 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000101 · wk-form4_1782249776.xml · derivative · entry 4

FOUSE JACQUALYN A · CIK 0001405288 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:22 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000101 · wk-form4_1782249776.xml · derivative · entry 3

FOUSE JACQUALYN A · CIK 0001405288 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:22 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000101 · wk-form4_1782249776.xml · derivative · entry 2

FOUSE JACQUALYN A · CIK 0001405288 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:22 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000101 · wk-form4_1782249776.xml · nonDerivative · entry 1

FOUSE JACQUALYN A · CIK 0001405288 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,156

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:20 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000095 · wk-form4_1782249639.xml · derivative · entry 4

Scadden David · CIK 0001707715 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:20 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000095 · wk-form4_1782249639.xml · derivative · entry 3

Scadden David · CIK 0001707715 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:20 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000095 · wk-form4_1782249639.xml · derivative · entry 2

Scadden David · CIK 0001707715 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:20 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000095 · wk-form4_1782249639.xml · nonDerivative · entry 1

Scadden David · CIK 0001707715 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,419

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:19 UTC GrantStock options (right to buy) · Derivative 14,950 $0.00 Strike: $34.16 $0.00
Disclosure

SEC source: 0001439222-26-000093 · wk-form4_1782249570.xml · derivative · entry 4

Smith Cynthia · CIK 0001609480 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,950

Underlying: Common stock · 14,950 shares

Expires 2036-06-18

F4 · derivative.exercise_date: These options were granted on June 18, 2026. The shares underlying these options vest as to 100% of the underlying shares on June 18, 2027.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:19 UTC GrantRestricted stock units · Derivative 2,927 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000093 · wk-form4_1782249570.xml · derivative · entry 3

Smith Cynthia · CIK 0001609480 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,927

Underlying: Common stock · 2,927 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F3 · derivative.expiration_date: The restricted stock units were granted on June 18, 2026. The shares underlying the stock units will vest in full on June 18, 2027. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:19 UTC Exercise / conversionRestricted stock units · Derivative 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000093 · wk-form4_1782249570.xml · derivative · entry 2

Smith Cynthia · CIK 0001609480 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 2,816 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 18, 2025. The shares underlying the stock units will vest in full on June 18, 2026. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:19 UTC Exercise / conversionCommon stock 2,816 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000093 · wk-form4_1782249570.xml · nonDerivative · entry 1

Smith Cynthia · CIK 0001609480 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,230

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:17 UTC
Goff BrianDirector · Chief Executive Officer
GrantRestricted stock units · Derivative 39,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000089 · wk-form4_1782249456.xml · derivative · entry 2

Goff Brian · CIK 0001546216 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,000

Underlying: Common stock · 39,000 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:17 UTC
Goff BrianDirector · Chief Executive Officer
Exercise / conversionPerformance share units · Derivative 39,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000089 · wk-form4_1782249456.xml · derivative · entry 1

Goff Brian · CIK 0001546216 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,000

Underlying: Common stock · 39,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:18 UTC
Viswanadhan KrishnanChief Strategy and Operations
GrantRestricted stock units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000091 · wk-form4_1782249510.xml · derivative · entry 2

Viswanadhan Krishnan · CIK 0001999913 · Chief Strategy and Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 5, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 5, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:18 UTC
Viswanadhan KrishnanChief Strategy and Operations
Exercise / conversionPerformance share units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000091 · wk-form4_1782249510.xml · derivative · entry 1

Viswanadhan Krishnan · CIK 0001999913 · Chief Strategy and Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 5, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 5, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:16 UTC
Burns James WilliamChief Legal Officer
GrantRestricted stock units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000087 · wk-form4_1782249398.xml · derivative · entry 2

Burns James William · CIK 0001900772 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document
June 18, 2026 Filed Jun 23, 2026 21:16 UTC
Burns James WilliamChief Legal Officer
Exercise / conversionPerformance share units · Derivative 3,000 $0.00 $0.00
Disclosure

SEC source: 0001439222-26-000087 · wk-form4_1782249398.xml · derivative · entry 1

Burns James William · CIK 0001900772 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common stock · 3,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

F2 · derivative.expiration_date: Performance stock units were granted on March 1, 2025, and provide for the vesting of underlying shares upon the achievement of three specified clinical and research milestones established by the compensation & people committee, or board of directors, as applicable. The performance criteria for the specified research milestone was determined by the compensation & people committee to be met as of June 18, 2026. The shares related to such milestone will vest on December 31, 2027, subject to the recipient's continued service.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.