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person · Reporting owner

MARAGANORE JOHN

Disclosed activity across 9 companies

Tapewire entity
32216
SEC CIK
0001180432

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AGIOS PHARMACEUTICALS, INC.AGIO · Entity 4499DirectorDecember 31, 2022February 03, 2023
ALNYLAM PHARMACEUTICALS, INC.ALNY · Entity 3132Director · Chief Executive OfficerDecember 21, 2021December 23, 2021
Beam Therapeutics Inc.BEAM · Entity 4227DirectorJune 03, 2026June 05, 2026
Hemab Therapeutics Holdings, Inc.COAG · Entity 4476DirectorJanuary 29, 2026May 04, 2026
Kymera Therapeutics, Inc.KYMR · Entity 3545DirectorJune 24, 2026June 25, 2026
PROKIDNEY CORP.PROK · Entity 5181DirectorJune 29, 2023July 03, 2023
Rapport Therapeutics, Inc.RAPP · Entity 4394DirectorJune 10, 2026June 10, 2026
TAKEDA PHARMACEUTICAL CO LTDTAK · Entity 2662DirectorJuly 01, 2026July 06, 2026
bluebird bio, Inc.BLUE · Entity 78923DirectorSeptember 14, 2017September 18, 2017

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AGIOS PHARMACEUTICALS, INC.

Report date December 31, 2022 · Filed February 03, 2023

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common stockSEC Table I · non-derivativeDirect28,528 Reported balance After 2022-09-20 transaction · row 1
1 source row

Row 1 · 2022-09-20 · Gift · Disposed 1,500 · Balance 28,528

F1: This disposition reflects a bona fide gift of 1,500 shares to charity.

Filing footnotes · ownership attribution and instrument terms

F1: This disposition reflects a bona fide gift of 1,500 shares to charity.

ALNYLAM PHARMACEUTICALS, INC.

Report date December 21, 2021 · Filed December 23, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect227,663 Ending reported balance After 2021-12-22 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2021-12-21 · Grant · Acquired 14,167 · Balance 234,299

F1: On February 28, 2019, the reporting person was granted performance-based restricted stock units (PSU) in connection with the 2018 year-end compensation review. One third of the PSU award vests upon the achievement of each of three specific clinical development, regulatory or commercial events. The People, Culture and Compensation Committee of the Board determined that the final performance criterion was met and the final one-third of the PSU award vested as of December 21, 2021.

Row 2 · 2021-12-22 · Tax withholding · Disposed 6,315 · Balance 227,984

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Row 3 · 2021-12-22 · Tax withholding · Disposed 2 · Balance 227,982

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Row 4 · 2021-12-22 · Tax withholding · Disposed 319 · Balance 227,663

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Common StockSEC Table I · non-derivativeIndirectby Managed Account3,133 Reported balance Holding disclosure · report date 2021-12-21 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 3,133

F3: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Filing footnotes · ownership attribution and instrument terms

F1: On February 28, 2019, the reporting person was granted performance-based restricted stock units (PSU) in connection with the 2018 year-end compensation review. One third of the PSU award vests upon the achievement of each of three specific clinical development, regulatory or commercial events. The People, Culture and Compensation Committee of the Board determined that the final performance criterion was met and the final one-third of the PSU award vested as of December 21, 2021.

F2: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

F3: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Beam Therapeutics Inc.

Report date June 03, 2026 · Filed June 05, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $29.55 · Expires 2036-06-03Direct19,676 Reported balance After 2026-06-03 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-03 · Grant · Acquired 19,676 · Balance 19,676

F1: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Hemab Therapeutics Holdings, Inc.

Report date January 29, 2026 · Filed May 04, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect35,948 Ending reported balance After 2026-05-04 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2026-05-04 · Conversion · Acquired 17,974 · Balance 17,974

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Row 2 · 2026-05-04 · Conversion · Acquired 17,974 · Balance 35,948

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Warrants (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.00 · Expires 2036-01-28Direct107,338 Reported balance After 2026-01-29 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-01-29 · Grant · Acquired 107,338 · Balance 107,338

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Series B Preferred StockSEC Table II · derivative / convertible securityDirect0 Reported balance After 2026-05-04 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-05-04 · Conversion · Disposed 817 · Balance 0

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Series C Preferred StockSEC Table II · derivative / convertible securityDirect0 Reported balance After 2026-05-04 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-05-04 · Conversion · Disposed 817 · Balance 0

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Filing footnotes · ownership attribution and instrument terms

F1: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Kymera Therapeutics, Inc.

Report date June 24, 2026 · Filed June 25, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $99.87 · Expires 2036-06-23Direct6,068 Reported balance After 2026-06-24 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-24 · Grant · Acquired 6,068 · Balance 6,068

F1: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.

PROKIDNEY CORP.

Report date June 29, 2023 · Filed July 03, 2023

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Director stock option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $10.56 · Expires 2033-06-29Direct48,128 Reported balance After 2023-06-29 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2023-06-29 · Grant · Acquired 48,128 · Balance 48,128

F1: These options were granted under the Issuer's non-employee director compensation policy.

F2: The options will vest in full on the sooner of the one-year anniversary of the date of grant or the date of Company's next annual general shareholder meeting.

Filing footnotes · ownership attribution and instrument terms

F1: These options were granted under the Issuer's non-employee director compensation policy.

F2: The options will vest in full on the sooner of the one-year anniversary of the date of grant or the date of Company's next annual general shareholder meeting.

Rapport Therapeutics, Inc.

Report date June 10, 2026 · Filed June 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.21 · Expires 2036-06-10Direct15,200 Reported balance After 2026-06-10 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-06-10 · Grant · Acquired 15,200 · Balance 15,200

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

TAKEDA PHARMACEUTICAL CO LTD

Report date July 01, 2026 · Filed July 06, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeDirect10,400 Reported balance After 2026-07-01 transaction · row 1 Account or security details depend on footnotes; rows are not merged.
1 source row

Row 1 · 2026-07-01 · Grant · Acquired 3,800 · Balance 10,400

F1: Represents an award of restricted stock units (RSU). Each RSU represents a contingent right to receive one Ordinary Share, which will be converted into an equivalent number of American Depositary Shares following vest. The RSUs vest on June 1, 2029.

F2: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

Tax Obligation AwardSEC Table II · derivative / convertible security · Expires 2026-06-01Direct0 Reported balance After 2026-07-10 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-07-10 · Disposition to issuer · Disposed 1,152 · Balance 0

F3: Each Tax Obligation Award was the economic equivalent of one Ordinary Share that, upon vest, was converted into to a cash payment primarily to cover tax obligations. Any remaining proceeds from the disposition of the associated Ordinary Shares will be delivered to the reporting person on July 10.

F4: The price reported in Column 8 is a weighted average price denominated in Yen. These shares were sold in transactions at prices ranging from JPY 4,883 to JPY 5,045, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Tax Obligation AwardSEC Table II · derivative / convertible security · Expires 2029-06-01Direct1,319 Reported balance After 2026-07-01 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-07-01 · Grant · Acquired 1,319 · Balance 1,319

F5: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

American Depositary SharesSEC Table I · non-derivativeDirect13,800 Reported balance Holding disclosure · report date 2026-07-01 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 13,800

F2: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

Filing footnotes · ownership attribution and instrument terms

F1: Represents an award of restricted stock units (RSU). Each RSU represents a contingent right to receive one Ordinary Share, which will be converted into an equivalent number of American Depositary Shares following vest. The RSUs vest on June 1, 2029.

F2: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

F3: Each Tax Obligation Award was the economic equivalent of one Ordinary Share that, upon vest, was converted into to a cash payment primarily to cover tax obligations. Any remaining proceeds from the disposition of the associated Ordinary Shares will be delivered to the reporting person on July 10.

F4: The price reported in Column 8 is a weighted average price denominated in Yen. These shares were sold in transactions at prices ranging from JPY 4,883 to JPY 5,045, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

F5: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

bluebird bio, Inc.

Report date September 14, 2017 · Filed September 18, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect5,843 Ending reported balance After 2017-09-14 transaction · row 3
3 source rows · reconciled sequence

Row 1 · 2017-09-14 · Exercise / conversion · Acquired 18,868 · Balance 24,711

Row 2 · 2017-09-14 · Sale · Disposed 18,268 · Balance 6,443

F1: The range in prices for the transaction reported on this line was $130.80 to $131.75. The average weighted price was $131.1935. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Row 3 · 2017-09-14 · Sale · Disposed 600 · Balance 5,843

F2: The range in prices for the transaction reported on this line was $131.80 to $131.90. The average weighted price was $131.8167. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $2.09 · Expires 2022-01-08Direct0 Reported balance After 2017-09-14 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2017-09-14 · Exercise / conversion · Acquired 18,868 · Balance 0

F3: This option vests in 48 equal monthly installments, commencing on April 1, 2011.

Filing footnotes · ownership attribution and instrument terms

F1: The range in prices for the transaction reported on this line was $130.80 to $131.75. The average weighted price was $131.1935. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

F2: The range in prices for the transaction reported on this line was $131.80 to $131.90. The average weighted price was $131.8167. The reporting person will provide, upon request by the SEC, the issuer or security holder of the issuer, full information regarding the number of shares sold at each separate price.

F3: This option vests in 48 equal monthly installments, commencing on April 1, 2011.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
July 10, 2026 Filed Jul 6, 2026 22:28 UTC TAKEDA PHARMACEUTICAL CO LTD TAK · Entity 2662 Disposition to issuerTax Obligation Award · Derivative 1,152 $4,931.20 $5,680,742.40
Disclosure

SEC source: 0001395064-26-000275 · wk-form4_1783376919.xml · derivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 1,152 shares

Expires 2026-06-01

F3 · derivative.exercise_price: Each Tax Obligation Award was the economic equivalent of one Ordinary Share that, upon vest, was converted into to a cash payment primarily to cover tax obligations. Any remaining proceeds from the disposition of the associated Ordinary Shares will be delivered to the reporting person on July 10.

F3 · date: Each Tax Obligation Award was the economic equivalent of one Ordinary Share that, upon vest, was converted into to a cash payment primarily to cover tax obligations. Any remaining proceeds from the disposition of the associated Ordinary Shares will be delivered to the reporting person on July 10.

F4 · price: The price reported in Column 8 is a weighted average price denominated in Yen. These shares were sold in transactions at prices ranging from JPY 4,883 to JPY 5,045, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.

Read SEC document
July 01, 2026 Filed Jul 6, 2026 22:28 UTC TAKEDA PHARMACEUTICAL CO LTD TAK · Entity 2662 GrantTax Obligation Award · Derivative 1,319 $0.00 $0.00
Disclosure

SEC source: 0001395064-26-000275 · wk-form4_1783376919.xml · derivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,319

Underlying: Ordinary Shares · 1,319 shares

Expires 2029-06-01

F5 · derivative.exercise_price: Each Tax Obligation Award is the economic equivalent of one Ordinary Share that, upon vest, will be converted to a cash payment primarily to cover tax obligations at the then-current market price of the Ordinary Shares.

Read SEC document
July 01, 2026 Filed Jul 6, 2026 22:28 UTC TAKEDA PHARMACEUTICAL CO LTD TAK · Entity 2662 GrantOrdinary Shares 3,800 $0.00 $0.00
Disclosure

SEC source: 0001395064-26-000275 · wk-form4_1783376919.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,400

F1 · kind: Represents an award of restricted stock units (RSU). Each RSU represents a contingent right to receive one Ordinary Share, which will be converted into an equivalent number of American Depositary Shares following vest. The RSUs vest on June 1, 2029.

F2 · balance_after: Reflects the conversion of 3,100 Ordinary Shares into 6,200 American Depositary Shares upon vesting of RSUs.

Read SEC document
June 24, 2026 Filed Jun 25, 2026 22:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 GrantStock Option (Right to Buy) · Derivative 6,068 $0.00 Strike: $99.87 $0.00
Disclosure

SEC source: 0001193125-26-283137 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,068

Underlying: Common Stock · 6,068 shares

Expires 2036-06-23

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.

Read SEC document
June 10, 2026 Filed Jun 10, 2026 21:57 UTC Rapport Therapeutics, Inc. RAPP · Entity 4394 GrantStock Option (Right to Buy) · Derivative 15,200 $0.00 Strike: $35.21 $0.00
Disclosure

SEC source: 0001193125-26-266155 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,200

Underlying: Common Stock · 15,200 shares

Expires 2036-06-10

F1 · derivative.exercise_date: The shares underlying this option shall vest upon the earlier of (i) June 10, 2027 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 03, 2026 Filed Jun 5, 2026 20:05 UTC Beam Therapeutics Inc. BEAM · Entity 4227 GrantStock Option (Right to Buy) · Derivative 19,676 $0.00 Strike: $29.55 $0.00
Disclosure

SEC source: 0001193125-26-259524 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,676

Underlying: Common Stock · 19,676 shares

Expires 2036-06-03

F1 · derivative.exercise_date: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Read SEC document
May 04, 2026 Filed May 4, 2026 20:20 UTC Hemab Therapeutics Holdings, Inc. COAG · Entity 4476 ConversionSeries C Preferred Stock · Derivative 817 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-204048 · ownership.xml · derivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,974 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2 · derivative.exercise_date: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F2 · derivative.expiration_date: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Read SEC document
May 04, 2026 Filed May 4, 2026 20:20 UTC Hemab Therapeutics Holdings, Inc. COAG · Entity 4476 ConversionSeries B Preferred Stock · Derivative 817 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-204048 · ownership.xml · derivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 17,974 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

F2 · derivative.exercise_date: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

F2 · derivative.expiration_date: Each share of Series B Preferred Stock and Series C Preferred Stock converted into 22 shares of common stock without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.

Read SEC document
May 04, 2026 Filed May 4, 2026 20:20 UTC Hemab Therapeutics Holdings, Inc. COAG · Entity 4476 ConversionCommon Stock 17,974 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-204048 · ownership.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,948

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Read SEC document
May 04, 2026 Filed May 4, 2026 20:20 UTC Hemab Therapeutics Holdings, Inc. COAG · Entity 4476 ConversionCommon Stock 17,974 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-204048 · ownership.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,974

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Read SEC document
January 29, 2026 Filed May 4, 2026 20:20 UTC Hemab Therapeutics Holdings, Inc. COAG · Entity 4476 GrantWarrants (Right to Buy) · Derivative 107,338 $0.00 Strike: $6.00 $0.00
Disclosure

SEC source: 0001193125-26-204048 · ownership.xml · derivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,338

Underlying: Common Stock · 107,338 shares

Expires 2036-01-28

F1 · derivative.exercise_date: The warrant was granted on January 29, 2026. The shares underlying the warrant vest over three years in equal monthly installments from January 1, 2026 through January 1, 2029.

Read SEC document
June 25, 2025 Filed Jun 27, 2025 01:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 GrantStock Option (Right to Buy) · Derivative 16,000 $0.00 Strike: $46.47 $0.00
Disclosure

SEC source: 0000950170-25-090582 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2035-06-24

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 25, 2026 and (ii) the date of the next annual meeting of the Issuer's stockholders.

Read SEC document
June 17, 2025 Filed Jun 18, 2025 20:15 UTC Rapport Therapeutics, Inc. RAPP · Entity 4394 GrantStock Option (Right to Buy) · Derivative 21,850 $0.00 Strike: $10.95 $0.00
Disclosure

SEC source: 0000950170-25-087902 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,850

Underlying: Common Stock · 21,850 shares

Expires 2035-06-17

F1 · derivative.exercise_date: The shares underlying this option shall vest upon the earlier of (i) June 17, 2026 and (ii) the date of the next Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 04, 2025 Filed Jun 6, 2025 20:05 UTC Beam Therapeutics Inc. BEAM · Entity 4227 GrantStock Option (Right to Buy) · Derivative 33,662 $0.00 Strike: $17.15 $0.00
Disclosure

SEC source: 0000950170-25-083053 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,662

Underlying: Common Stock · 33,662 shares

Expires 2035-06-04

F1 · derivative.exercise_date: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Read SEC document
June 18, 2024 Filed Jun 20, 2024 21:00 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 GrantStock Option (Right to Buy) · Derivative 16,000 $0.00 Strike: $31.20 $0.00
Disclosure

SEC source: 0000950170-24-075709 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2034-06-17

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 18, 2025 and (ii) the date of the next annual meeting of the Issuer's stockholders.

Read SEC document
June 05, 2024 Filed Jun 7, 2024 20:47 UTC Beam Therapeutics Inc. BEAM · Entity 4227 GrantStock Option (Right to Buy) · Derivative 23,114 $0.00 Strike: $24.49 $0.00
Disclosure

SEC source: 0000950170-24-070790 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,114

Underlying: Common Stock · 23,114 shares

Expires 2034-06-05

F1 · derivative.exercise_date: The option vests in full on the earlier of the first anniversary of the date of grant and immediately prior to the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Read SEC document
June 29, 2023 Filed Jul 3, 2023 13:17 UTC PROKIDNEY CORP. PROK · Entity 5181 GrantDirector stock option (right to buy) · Derivative 48,128 $0.00 Strike: $10.56 $0.00
Disclosure

SEC source: 0001209191-23-040423 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,128

Underlying: Class A Ordinary Shares · 48,128 shares

Expires 2033-06-29

F1 · shares: These options were granted under the Issuer's non-employee director compensation policy.

F2 · derivative.exercise_date: The options will vest in full on the sooner of the one-year anniversary of the date of grant or the date of Company's next annual general shareholder meeting.

Read SEC document
June 15, 2023 Filed Jun 20, 2023 20:15 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 GrantStock Option (Right to Buy) · Derivative 12,000 $0.00 Strike: $27.67 $0.00
Disclosure

SEC source: 0000899243-23-015965 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 12,000 shares

Expires 2033-06-14

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 15, 2024 and (ii) the date of the next annual meeting of the Issuer's stockholders.

Read SEC document
June 06, 2023 Filed Jun 8, 2023 20:47 UTC Beam Therapeutics Inc. BEAM · Entity 4227 GrantStock Option (Right to Buy) · Derivative 16,532 $0.00 Strike: $34.33 $0.00
Disclosure

SEC source: 0000950170-23-027037 · ownership.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,532

Underlying: Common Stock · 16,532 shares

Expires 2033-06-06

F1 · derivative.exercise_date: The option vests in full on the earlier of the first anniversary of the date of grant and the date of the next year's annual meeting of stockholders, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Read SEC document
September 20, 2022 Filed Feb 3, 2023 21:06 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 GiftCommon stock 1,500 $0.00 $0.00
Disclosure

SEC source: 0001439222-23-000012 · wf-form5_167545833893976.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,528

F1 · kind: This disposition reflects a bona fide gift of 1,500 shares to charity.

Read SEC document
September 01, 2022 Filed Sep 2, 2022 20:05 UTC Beam Therapeutics Inc. BEAM · Entity 4227 GrantStock Option (Right to Buy) · Derivative 10,391 $0.00 Strike: $55.58 $0.00
Disclosure

SEC source: 0000899243-22-030271 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,391

Underlying: Common Stock · 10,391 shares

Expires 2032-09-01

F1 · derivative.exercise_date: The option vests in full on the first anniversary of the date of grant, subject to the reporting person's continued service to the board of directors of Beam Therapeutics Inc. through the vesting date.

Read SEC document
July 11, 2022 Filed Jul 14, 2022 01:29 UTC PROKIDNEY CORP. PROK · Entity 5181 GrantCommon Units in ProKidney LP · Derivative 614,013 $0.00 $0.00
Disclosure

SEC source: 0000950103-22-012371 · dp177037_4-maraganore.xml · derivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 614,013

Underlying: Class A Ordinary Shares · 614,013 shares

Expires not disclosed

F3 · security: Each Common Unit may, at the election of the reporting person and subject to the limitations set forth in the Exchange Agreement and the Second Amended and Restated Company Partnership Agreement, be exchanged, together with the paired Class B Ordinary Share, into a Class A Ordinary Share on a one-for-one basis.

F3 · derivative.exercise_price: Each Common Unit may, at the election of the reporting person and subject to the limitations set forth in the Exchange Agreement and the Second Amended and Restated Company Partnership Agreement, be exchanged, together with the paired Class B Ordinary Share, into a Class A Ordinary Share on a one-for-one basis.

F4 · derivative.exercise_price: These 450,156 Common Units and 163,857 Restricted Common Units of ProKidney Equity LLC that upon vesting will settle in Common Units ("PMEL RCUs") were received pursuant to the terms of the Business Combination Agreement in exchange for historical interests held by the reporting person in ProKidney. The PMEL RCUs vest in installments over a period through June 1, 2025. The Common Units and the PMEL RCUs do not expire.

F4 · derivative.exercise_date: These 450,156 Common Units and 163,857 Restricted Common Units of ProKidney Equity LLC that upon vesting will settle in Common Units ("PMEL RCUs") were received pursuant to the terms of the Business Combination Agreement in exchange for historical interests held by the reporting person in ProKidney. The PMEL RCUs vest in installments over a period through June 1, 2025. The Common Units and the PMEL RCUs do not expire.

F4 · derivative.expiration_date: These 450,156 Common Units and 163,857 Restricted Common Units of ProKidney Equity LLC that upon vesting will settle in Common Units ("PMEL RCUs") were received pursuant to the terms of the Business Combination Agreement in exchange for historical interests held by the reporting person in ProKidney. The PMEL RCUs vest in installments over a period through June 1, 2025. The Common Units and the PMEL RCUs do not expire.

Read SEC document
July 11, 2022 Filed Jul 14, 2022 01:29 UTC PROKIDNEY CORP. PROK · Entity 5181 GrantClass B Ordinary Shares · Derivative 614,013 $0.00 $0.00
Disclosure

SEC source: 0000950103-22-012371 · dp177037_4-maraganore.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 614,013

Underlying: Class A Ordinary Shares · 614,013 shares

Expires not disclosed

F1 · derivative.exercise_price: Each Class B Ordinary Share has no economic rights but entitles the reporting person to vote on all matters on which shareholders of the issuer vote and may, at the election of the reporting person and subject to the limitations set forth in the Exchange Agreement and the Second Amended and Restated Company Partnership Agreement (each as defined and as described in the issuer's Definitive Proxy Statement filed with the Securities and Exchange Commission on June 10, 2022), be exchanged, together with the paired Common Unit in ProKidney LP ("ProKidney") (a "Common Unit"), for a Class A Ordinary Share on a one-for-one basis.

F2 · derivative.exercise_price: These 450,156 Class B Ordinary Shares and 163,857 Restricted Stock Rights in respect of Class B Ordinary Shares ("Class B PMEL RSRs") were received pursuant to the terms of the Business Combination Agreement by and between the issuer and ProKidney, dated as of January 18, 2022 (the "Business Combination Agreement") in exchange for historical interests held by the reporting person in ProKidney. The Class B PMEL RSRs vest in installments over a period through June 1, 2025, and upon vesting are immediately settled as Class B Ordinary Shares. The Class B Ordinary Shares and Class B PMEL RSRs do not expire.

F2 · derivative.exercise_date: These 450,156 Class B Ordinary Shares and 163,857 Restricted Stock Rights in respect of Class B Ordinary Shares ("Class B PMEL RSRs") were received pursuant to the terms of the Business Combination Agreement by and between the issuer and ProKidney, dated as of January 18, 2022 (the "Business Combination Agreement") in exchange for historical interests held by the reporting person in ProKidney. The Class B PMEL RSRs vest in installments over a period through June 1, 2025, and upon vesting are immediately settled as Class B Ordinary Shares. The Class B Ordinary Shares and Class B PMEL RSRs do not expire.

F2 · derivative.expiration_date: These 450,156 Class B Ordinary Shares and 163,857 Restricted Stock Rights in respect of Class B Ordinary Shares ("Class B PMEL RSRs") were received pursuant to the terms of the Business Combination Agreement by and between the issuer and ProKidney, dated as of January 18, 2022 (the "Business Combination Agreement") in exchange for historical interests held by the reporting person in ProKidney. The Class B PMEL RSRs vest in installments over a period through June 1, 2025, and upon vesting are immediately settled as Class B Ordinary Shares. The Class B Ordinary Shares and Class B PMEL RSRs do not expire.

Read SEC document
June 21, 2022 Filed Jun 23, 2022 20:11 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 GrantStock options (right to buy) · Derivative 29,307 $0.00 Strike: $18.09 $0.00
Disclosure

SEC source: 0001439222-22-000064 · wf-form4_165601503086291.xml · derivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,307

Underlying: Common stock · 29,307 shares

Expires 2032-06-21

F3 · derivative.exercise_date: This option was granted on June 21, 2022. The shares underlying this option vest as to 100% of the underlying shares on June 21, 2023.

Read SEC document
June 21, 2022 Filed Jun 23, 2022 20:11 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 GrantRestricted stock unit · Derivative 4,975 $0.00 $0.00
Disclosure

SEC source: 0001439222-22-000064 · wf-form4_165601503086291.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,975

Underlying: Common stock · 4,975 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on June 21, 2022. The shares underlying the stock units will vest in full on June 21, 2023. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

F2 · derivative.expiration_date: The restricted stock units were granted on June 21, 2022. The shares underlying the stock units will vest in full on June 21, 2023. Vested shares will be delivered to the reporting person within three business days after such shares become vested.

Read SEC document
May 20, 2022 Filed May 24, 2022 20:10 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 Exercise / conversionRestricted stock unit · Derivative 1,585 $0.00 $0.00
Disclosure

SEC source: 0001439222-22-000049 · wf-form4_165342304013278.xml · derivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common stock · 1,585 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.

F2 · derivative.exercise_date: The restricted stock units were granted on May 20, 2021. The shares underlying the stock units will vest in full on May 20, 2022. Vested shares will be delivered to the reporting person within three business days after such shares become vested

F2 · derivative.expiration_date: The restricted stock units were granted on May 20, 2021. The shares underlying the stock units will vest in full on May 20, 2022. Vested shares will be delivered to the reporting person within three business days after such shares become vested

Read SEC document
May 20, 2022 Filed May 24, 2022 20:10 UTC AGIOS PHARMACEUTICALS, INC. AGIO · Entity 4499 Exercise / conversionCommon stock 1,585 $0.00 $0.00
Disclosure

SEC source: 0001439222-22-000049 · wf-form4_165342304013278.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,028

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 18, 2022 Filed Jan 19, 2022 22:35 UTC Kymera Therapeutics, Inc. KYMR · Entity 3545 GrantStock Option (Right to Buy) · Derivative 24,000 $0.00 Strike: $39.61 $0.00
Disclosure

SEC source: 0000899243-22-002452 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,000

Underlying: Common Stock · 24,000 shares

Expires 2032-01-17

F1 · derivative.exercise_date: The shares subject to this option shall vest in thirty-six (36) equal monthly installments over three (3) years beginning on January 18, 2022.

Read SEC document
December 22, 2021 Filed Dec 23, 2021 22:00 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Tax withholdingCommon Stock 319 $186.02 $59,340.38
Disclosure

SEC source: 0001735276-21-000095 · edgardoc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 227,663

F2 · kind: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Read SEC document
December 22, 2021 Filed Dec 23, 2021 22:00 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Tax withholdingCommon Stock 2 $190.50 $381.00
Disclosure

SEC source: 0001735276-21-000095 · edgardoc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 227,982

F2 · kind: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Read SEC document
December 22, 2021 Filed Dec 23, 2021 22:00 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Tax withholdingCommon Stock 6,315 $189.13 $1,194,355.95
Disclosure

SEC source: 0001735276-21-000095 · edgardoc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 227,984

F2 · kind: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the PSU award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting event.

Read SEC document
December 21, 2021 Filed Dec 23, 2021 22:00 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 GrantCommon Stock 14,167 $0.00 $0.00
Disclosure

SEC source: 0001735276-21-000095 · edgardoc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 234,299

F1 · kind: On February 28, 2019, the reporting person was granted performance-based restricted stock units (PSU) in connection with the 2018 year-end compensation review. One third of the PSU award vests upon the achievement of each of three specific clinical development, regulatory or commercial events. The People, Culture and Compensation Committee of the Board determined that the final performance criterion was met and the final one-third of the PSU award vested as of December 21, 2021.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 839 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · derivative · entry 9

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,661

Underlying: Common Stock · 839 shares

Expires 2028-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 1,036 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · derivative · entry 8

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,964

Underlying: Common Stock · 1,036 shares

Expires 2024-12-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 1,124 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · derivative · entry 7

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,876

Underlying: Common Stock · 1,124 shares

Expires 2025-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 2,368 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · derivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,632

Underlying: Common Stock · 2,368 shares

Expires 2026-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 2,368 $42.22 $99,976.96
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 220,132

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 839 $119.13 $99,950.07
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 217,764

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 1,124 $88.95 $99,979.80
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 216,925

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 10, 2021 Filed Dec 14, 2021 21:05 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 1,036 $96.45 $99,922.20
Disclosure

SEC source: 0001735276-21-000091 · edgardoc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,801

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 33,978 $0.00 Strike: $7.10 $0.00
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · derivative · entry 8

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 33,978 shares

Expires 2021-11-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F8 · derivative.exercise_date: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 670 $174.34 $116,807.80
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · nonDerivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 214,765

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F6 · price: Sale prices ranged from $174.05 to $174.63.

Read SEC document
November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 683 $173.25 $118,329.75
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · nonDerivative · entry 5

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 215,435

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F5 · price: Sale prices ranged from $172.90 to $173.34.

Read SEC document
November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 14,518 $172.22 $2,500,289.96
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 216,118

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F4 · price: Sale prices ranged from $171.86 to $172.84.

Read SEC document
November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 7,742 $171.35 $1,326,591.70
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 230,636

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F3 · price: Sale prices ranged from $170.85 to $171.82.

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November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 10,365 $170.36 $1,765,781.40
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 238,378

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F2 · price: Sale prices ranged from $169.84 to $170.84.

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November 12, 2021 Filed Nov 12, 2021 22:52 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionCommon Stock 33,978 $7.10 $241,243.80
Disclosure

SEC source: 0001735276-21-000089 · edgardoc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 248,743

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,978 options exercised and sold by the reporting person were due to expire on November 30, 2021.

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November 05, 2021 Filed Nov 9, 2021 01:05 UTC Beam Therapeutics Inc. BEAM · Entity 4227 GrantStock Option (Right to Buy) · Derivative 13,133 $0.00 Strike: $89.53 $0.00
Disclosure

SEC source: 0000899243-21-043520 · doc4.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,133

Underlying: Common Stock · 13,133 shares

Expires 2031-11-05

F1 · derivative.exercise_date: The option vests as to one-third of the shares subject to the option on the first anniversary of the date of grant and in equal monthly installments as to the remainder of the shares for two years thereafter, subject to the Reporting Person's continued service with the Company through each vesting date.

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August 13, 2021 Filed Aug 16, 2021 20:38 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 Exercise / conversionStock Option (right to buy) · Derivative 33,979 $0.00 Strike: $7.10 $0.00
Disclosure

SEC source: 0001735276-21-000083 · edgardoc.xml · derivative · entry 8

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,978

Underlying: Common Stock · 33,979 shares

Expires 2021-11-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,979 options exercised and sold by the reporting person were due to expire on November 30, 2021.

F7 · derivative.exercise_date: The stock option vested as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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August 13, 2021 Filed Aug 16, 2021 20:38 UTC ALNYLAM PHARMACEUTICALS, INC. ALNY · Entity 3132 SaleCommon Stock 214 $201.55 $43,131.70
Disclosure

SEC source: 0001735276-21-000083 · edgardoc.xml · nonDerivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 214,765

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2020. The 33,979 options exercised and sold by the reporting person were due to expire on November 30, 2021.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.