MNPR

SEC source: 0001437749-26-029228 · rdgdoc.xml · nonDerivative · entry 1

Anderson Raymond · CIK 0001362489 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,775

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 Plan executed by the reporting person on May 26, 2026.

SEC source: 0001437749-26-022628 · rdgdoc.xml · derivative · entry 3

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,499

Underlying: Common Stock · 5,254 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F3 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On December 2, 2025, the reporting person was granted 13,919 restricted stock units, vesting 6/48ths (1,740) on June 30, 2026, and 3/48ths (870 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2029. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F3 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On December 2, 2025, the reporting person was granted 13,919 restricted stock units, vesting 6/48ths (1,740) on June 30, 2026, and 3/48ths (870 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2029. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-022628 · rdgdoc.xml · nonDerivative · entry 2

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,614

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-022628 · rdgdoc.xml · nonDerivative · entry 1

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,923

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-26-022630 · rdgdoc.xml · derivative · entry 4

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 93,403

Underlying: Common Stock · 12,873 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F4 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F6 · derivative.exercise_date: On December 2, 2025, the reporting person was granted 49,133 restricted stock units, vesting 6/48ths (6,142) on June 30, 2026, and 3/48ths (3,071 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2029. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F6 · derivative.expiration_date: On December 2, 2025, the reporting person was granted 49,133 restricted stock units, vesting 6/48ths (6,142) on June 30, 2026, and 3/48ths (3,071 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2029. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-022630 · rdgdoc.xml · nonDerivative · entry 2

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,267

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-022630 · rdgdoc.xml · nonDerivative · entry 1

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 103,351

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-26-022631 · rdgdoc.xml · derivative · entry 3

Vu Quan Anh · CIK 0001892297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,598

Underlying: Common Stock · 1,228 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F3 · derivative.exercise_date: On December 2, 2025, the reporting person was granted 9,826 restricted stock units, vesting 6/48ths (1,228) on June 30, 2026, and 3/48ths (614 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2029. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F3 · derivative.expiration_date: On December 2, 2025, the reporting person was granted 9,826 restricted stock units, vesting 6/48ths (1,228) on June 30, 2026, and 3/48ths (614 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2029. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-022631 · rdgdoc.xml · nonDerivative · entry 2

Vu Quan Anh · CIK 0001892297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,221

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-022631 · rdgdoc.xml · nonDerivative · entry 1

Vu Quan Anh · CIK 0001892297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,728

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-26-022164 · rdgdoc.xml · derivative · entry 1

Sweeny Nicole · CIK 0001827505 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,284

Underlying: Common Stock · 1,284 shares

Expires 2036-06-26

F1 · derivative.exercise_date: Options vest 50% on September 30, 2026, and 50% on December 31, 2026.

SEC source: 0001437749-26-011078 · rdgdoc.xml · derivative · entry 3

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,753

Underlying: Common Stock · 3,514 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F3 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F3 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-011078 · rdgdoc.xml · nonDerivative · entry 2

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,669

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-011078 · rdgdoc.xml · nonDerivative · entry 1

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,240

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-26-011079 · rdgdoc.xml · derivative · entry 4

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,276

Underlying: Common Stock · 6,732 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F4 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-011079 · rdgdoc.xml · nonDerivative · entry 2

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,478

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-011079 · rdgdoc.xml · nonDerivative · entry 1

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,450

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-26-006935 · rdgdoc.xml · derivative · entry 1

Rodriguez Susan · CIK 0001812511 · CCSO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,728

Underlying: Common Stock · 48,728 shares

Expires 2036-03-02

F1 · derivative.exercise_date: Options vest 6/48ths on September 2, 2026 and 1/48th per month thereafter.

SEC source: 0001437749-26-000304 · rdgdoc.xml · derivative · entry 1

RIOUX PATRICE · CIK 0001241033 · Acting Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 2,000 shares

Expires 2036-01-01

F1 · derivative.exercise_date: Stock Options vesting commenced on January 1, 2026 as follows: 1/12th of the 2,000 options vest on January 31, 2026 and each subsequent month-end thereafter.

SEC source: 0001437749-26-000305 · rdgdoc.xml · derivative · entry 3

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,267

Underlying: Common Stock · 4,326 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F3 · derivative.exercise_date: On February 2, 2022, the reporting person was granted 13,000 restricted stock units, vesting 6/48ths (1,625 shares) on June 30, 2022, and 3/48ths (813 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F3 · derivative.expiration_date: On February 2, 2022, the reporting person was granted 13,000 restricted stock units, vesting 6/48ths (1,625 shares) on June 30, 2022, and 3/48ths (813 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-000305 · rdgdoc.xml · nonDerivative · entry 2

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,726

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-000305 · rdgdoc.xml · nonDerivative · entry 1

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,615

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-26-000306 · rdgdoc.xml · derivative · entry 4

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 113,008

Underlying: Common Stock · 8,724 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F4 · derivative.exercise_date: On February 2, 2022, the reporting person was granted 31,905 restricted stock units, vesting 6/48ths (3,988 shares) on June 30, 2022, and 3/48ths (1,994 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F6 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On February 2, 2022, the reporting person was granted 31,905 restricted stock units, vesting 6/48ths (3,988 shares) on June 30, 2022, and 3/48ths (1,994 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F6 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-26-000306 · rdgdoc.xml · nonDerivative · entry 2

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,718

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-26-000306 · rdgdoc.xml · nonDerivative · entry 1

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 88,276

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-25-038804 · rdgdoc.xml · nonDerivative · entry 1

Vu Quan Anh · CIK 0001892297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,500

SEC source: 0001437749-25-038426 · rdgdoc.xml · nonDerivative · entry 2

KLAUSNER ARTHUR J · CIK 0001207790 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,762

F2 · price: The shares were sold in multiple transactions at prices ranging from $68.00 to $68.35, inclusive. This amount represents the weighted average sale price of such transactions. The reporting person undertakes to provide full information regarding the number of shares sold at each separate price upon request of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

SEC source: 0001437749-25-038426 · rdgdoc.xml · nonDerivative · entry 1

KLAUSNER ARTHUR J · CIK 0001207790 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,223

F1 · price: The shares were sold in multiple transactions at prices ranging from $67.00 to $67.28, inclusive. This amount represents the weighted average sale price of such transactions. The reporting person undertakes to provide full information regarding the number of shares sold at each separate price upon request of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

SEC source: 0001437749-25-038139 · rdgdoc.xml · nonDerivative · entry 1

Hendricks Diane · CIK 0001727478 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 567,580

F1 · kind: Reported disposition relates to pro rata distribution by Gem Pharmaceuticals, LLC ("Gem") to its members in which the reporting person has no pecuniary interest. Pharma Investments LLC ("Pharma") owns a controlling share of Gem and the reporting person, a manager of Gem, owns a controlling share of Pharma, so Pharma and its controlling shareholders have indirect control over the securities described herein. The managers of Gem and the controlling shareholders of Pharma each disclaim ownership of the shares of common stock owned by Gem, except to the extent of their pecuniary interest therein.

F1 · ownership.nature: Reported disposition relates to pro rata distribution by Gem Pharmaceuticals, LLC ("Gem") to its members in which the reporting person has no pecuniary interest. Pharma Investments LLC ("Pharma") owns a controlling share of Gem and the reporting person, a manager of Gem, owns a controlling share of Pharma, so Pharma and its controlling shareholders have indirect control over the securities described herein. The managers of Gem and the controlling shareholders of Pharma each disclaim ownership of the shares of common stock owned by Gem, except to the extent of their pecuniary interest therein.

SEC source: 0001437749-25-038138 · rdgdoc.xml · nonDerivative · entry 1

KLAUSNER ARTHUR J · CIK 0001207790 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,883

F1 · kind: Pro rata distribution from Gem Pharmaceuticals, LLC, of which the reporting person is a non-managing member.

SEC source: 0001437749-25-037167 · rdgdoc.xml · derivative · entry 1

Talukdar Lavina · CIK 0002059193 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,924

Underlying: Common Stock · 2,924 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 25% quarterly on March 31, 2026, June 30, 2026, September 30, 2026 and December 31, 2026.

SEC source: 0001437749-25-037171 · rdgdoc.xml · derivative · entry 2

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 52,593

Underlying: Common Stock · 13,919 shares

Expires not disclosed

F2 · derivative.exercise_date: RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.

F2 · derivative.expiration_date: RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.

SEC source: 0001437749-25-037171 · rdgdoc.xml · derivative · entry 1

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,969

Underlying: Common Stock · 8,969 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 6/48ths on June 30, 2026, and 1/48th per month thereafter.

SEC source: 0001437749-25-037170 · rdgdoc.xml · derivative · entry 1

STARR CHRISTOPHER M · CIK 0001235470 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,924

Underlying: Common Stock · 2,924 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 25% quarterly on March 31, 2026, June 30, 2026, September 30, 2026 and December 31, 2026.

SEC source: 0001437749-25-037169 · rdgdoc.xml · derivative · entry 1

KLAUSNER ARTHUR J · CIK 0001207790 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,924

Underlying: Common Stock · 2,924 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 25% quarterly on March 31, 2026, June 30, 2026, September 30, 2026 and December 31, 2026.

SEC source: 0001437749-25-037165 · rdgdoc.xml · derivative · entry 1

Tsuchimoto Kim R · CIK 0001333516 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,924

Underlying: Common Stock · 2,924 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 25% quarterly on March 31, 2026, June 30, 2026, September 30, 2026 and December 31, 2026.

SEC source: 0001437749-25-037168 · rdgdoc.xml · derivative · entry 1

Anderson Raymond · CIK 0001362489 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,924

Underlying: Common Stock · 2,924 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 25% quarterly on March 31, 2026, June 30, 2026, September 30, 2026 and December 31, 2026

SEC source: 0001437749-25-037164 · rdgdoc.xml · derivative · entry 2

Vu Quan Anh · CIK 0001892297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,826

Underlying: Common Stock · 9,826 shares

Expires not disclosed

F2 · derivative.exercise_date: RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.

F2 · derivative.expiration_date: RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.

SEC source: 0001437749-25-037164 · rdgdoc.xml · derivative · entry 1

Vu Quan Anh · CIK 0001892297 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,135

Underlying: Common Stock · 7,135 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 6/48ths on June 30, 2026, and 1/48th per month thereafter.

SEC source: 0001437749-25-037163 · rdgdoc.xml · derivative · entry 2

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,732

Underlying: Common Stock · 49,133 shares

Expires not disclosed

F2 · derivative.exercise_date: RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.

F2 · derivative.expiration_date: RSUs vest 6/48ths on June 30, 2026, and 3/48ths per quarter thereafter.

SEC source: 0001437749-25-037163 · rdgdoc.xml · derivative · entry 1

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,753

Underlying: Common Stock · 16,753 shares

Expires 2035-12-02

F1 · derivative.exercise_date: Options vest 6/48ths on June 30, 2026, and 1/48th per month thereafter.

SEC source: 0001437749-25-030285 · rdgdoc.xml · derivative · entry 3

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,674

Underlying: Common Stock · 4,327 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F3 · derivative.exercise_date: On February 2, 2022, the reporting person was granted 13,000 restricted stock units, vesting 6/48ths (1,625 shares) on June 30, 2022, and 3/48ths (813 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F3 · derivative.expiration_date: On February 2, 2022, the reporting person was granted 13,000 restricted stock units, vesting 6/48ths (1,625 shares) on June 30, 2022, and 3/48ths (813 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 15,647 restricted stock units, vesting 6/48ths (1,956 shares) on June 30, 2023, and 3/48ths (978 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 40,581 restricted stock units, vesting 6/48ths (5,073 shares) on June 30, 2025, and 3/48ths (2,536 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-25-030285 · rdgdoc.xml · nonDerivative · entry 2

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,289

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-25-030285 · rdgdoc.xml · nonDerivative · entry 1

Cittadine Andrew · CIK 0001863624 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,185

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-25-030284 · rdgdoc.xml · derivative · entry 4

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,599

Underlying: Common Stock · 8,726 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Represents shares acquired on vesting and settlement of restricted stock units.

F4 · derivative.exercise_date: On February 2, 2022, the reporting person was granted 31,905 restricted stock units, vesting 6/48ths (3,988 shares) on June 30, 2022, and 3/48ths (1,994 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.exercise_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F6 · derivative.exercise_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F4 · derivative.expiration_date: On February 2, 2022, the reporting person was granted 31,905 restricted stock units, vesting 6/48ths (3,988 shares) on June 30, 2022, and 3/48ths (1,994 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2025. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F5 · derivative.expiration_date: On February 1, 2023, the reporting person was granted 33,803 restricted stock units, vesting 6/48ths (4,225 shares) on June 30, 2023, and 3/48ths (2,113 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2026. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

F6 · derivative.expiration_date: On March 4, 2025, the reporting person was granted 79,899 restricted stock units of which 6,002 shares vested immediately as of the grant date. The remaining 73,897 restricted stock units vest 6/48ths (9,237 shares) on June 30, 2025, and 3/48ths (4,619 shares) every 3 months thereafter until the RSU is fully vested on December 31, 2028. Each restricted stock unit represents a contingent right to receive one share of common stock of the Issuer. Disposed of restricted stock units were surrendered in exchange for issuance of common stock upon vesting and settlement.

SEC source: 0001437749-25-030284 · rdgdoc.xml · nonDerivative · entry 2

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,552

F2 · shares: Represents shares withheld by the issuer to pay for the applicable withholding tax due upon vesting of restricted stock units.

SEC source: 0001437749-25-030284 · rdgdoc.xml · nonDerivative · entry 1

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 82,198

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Represents shares acquired on vesting and settlement of restricted stock units.

SEC source: 0001437749-25-029925 · rdgdoc.xml · nonDerivative · entry 1

Tactic Pharma LLC · CIK 0001727357 · 10% owner

Robinson Chandler · CIK 0001727334 · Director · Chief Executive Officer

Brown Michael J · CIK 0001035909 · Member of 10% Owner Group

O'Halloran Thomas V. · CIK 0001727481 · Member of 10% Owner Group

Mazar Andrew Paul · CIK 0001727393 · Member of 10% Owner Group

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 272,026

F1 · ownership.direct: This Form 4 is being filed on behalf of Tactic Pharma LLC, an Illinois limited liability company ("Tactic"), and its managers, Andrew P. Mazar, Chandler D. Robinson, Michael J. Brown, and Thomas V. O'Halloran (collectively, the "Reporting Persons"). The managers collectively have voting control over the securities described herein. The managers each disclaim ownership of the shares of common stock owned by Tactic, except to the extent of their pecuniary interest therein. The Reporting Persons are no longer subject to Section 16, except for Chandler D. Robinson, who serves as Chief Executive Officer of Monopar Therapeutics Inc.

SEC source: 0001437749-25-022862 · rdgdoc.xml · derivative · entry 4

STARR CHRISTOPHER M · CIK 0001235470 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 16,800 shares

Expires 2026-04-04

F4 · derivative.exercise_date: Reflects options to purchase up to 16,800 shares of common stock granted to Dr. Starr on April 4, 2016, for his services as a director of Monopar Therapeutics. The options vested 6/12ths upon the grant date and 3/12th every 6 months thereafter.

SEC source: 0001437749-25-022862 · rdgdoc.xml · nonDerivative · entry 2

STARR CHRISTOPHER M · CIK 0001235470 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,173

F2 · price: The shares were sold in multiple transactions at prices ranging from $40.00 to $40.25, inclusive. This amount represents the weighted average sale price of such transactions. The reporting person undertakes to provide full information regarding the number of shares sold at each separate price upon request of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.