MAZE

SEC source: 0002050172-25-000007 · form4-12312025_091232.xml · nonDerivative · entry 1

Bernstein Harold · CIK 0002050172 · President, R&D & CMO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 45,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

SEC source: 0002050422-25-000007 · form4-12312025_091203.xml · derivative · entry 9

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,834

Underlying: Common Stock · 9,876 shares

Expires 2034-04-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F6 · derivative.exercise_date: The option vested or vests as to 1/48th of the total award monthly, with the first tranche vested on April 1, 2024, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0002050422-25-000007 · form4-12312025_091203.xml · derivative · entry 8

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,396

Underlying: Common Stock · 124 shares

Expires 2031-02-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F5 · derivative.exercise_date: The option is fully vested. Pursuant to the terms of the reporting person's award agreement with the Issuer, the award became fully vested on February 1, 2025.

SEC source: 0002050422-25-000007 · form4-12312025_091203.xml · nonDerivative · entry 4

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,965

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $41.04 to $41.29 per share, inclusive.

SEC source: 0002050422-25-000007 · form4-12312025_091203.xml · nonDerivative · entry 3

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,565

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.04 to $40.94 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and in footnotes 3 and 4 of this Form 4.

SEC source: 0002050422-25-000007 · form4-12312025_091203.xml · nonDerivative · entry 2

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,965

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

SEC source: 0002050422-25-000007 · form4-12312025_091203.xml · nonDerivative · entry 1

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,089

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

SEC source: 0002050167-25-000007 · form4-12312025_091220.xml · derivative · entry 6

Dandekar Atul · CIK 0002050167 · CSBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 74,243

Underlying: Common Stock · 72,400 shares

Expires 2031-04-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F5 · derivative.exercise_date: The option is fully vested. Pursuant to the terms of the reporting person's award agreement with the Issuer, the award became fully vested on March 17, 2025.

SEC source: 0002050167-25-000007 · form4-12312025_091220.xml · nonDerivative · entry 3

Dandekar Atul · CIK 0002050167 · CSBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,503

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F4 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.99 to $41.51 per share, inclusive.

SEC source: 0002050167-25-000007 · form4-12312025_091220.xml · nonDerivative · entry 2

Dandekar Atul · CIK 0002050167 · CSBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,538

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.99 to $40.985 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and in footnote 4 of this Form 4.

SEC source: 0002050167-25-000007 · form4-12312025_091220.xml · nonDerivative · entry 1

Dandekar Atul · CIK 0002050167 · CSBO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 82,903

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025.

F2 · balance_after: The reported total includes 1,562 shares of the Issuer's Common Stock acquired by the reporting person in one or more transactions with the Issuer pursuant to its Employee Stock Purchase Plan, which transactions are exempt pursuant to Rules 16a3(f)(1)(i)(B) and 16b3(c).

SEC source: 0001192591-25-000010 · form4-11212025_091144.xml · nonDerivative · entry 1

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,113

F1 · kind: The reported transaction represents the receipt by the reporting person of his pro rata share of a distribution made by one or more entities affiliated with Third Rock Ventures, for no consideration, of shares of the Issuer's common stock, which distribution was made in accordance with the exemption afforded by Rule 16a-9 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001193125-25-266981 · ownership.xml · nonDerivative · entry 1

Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner

Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner

TRV GP IV, LLC · CIK 0001688325 · 10% owner

Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner

Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner

TRV GP V, LLC · CIK 0001990717 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,473,958

F1 · kind: On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended.

F1 · price: On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended.

F2 · ownership.direct: The shares are held directly by TRV IV. The general partner of TRV IV is TRV GP IV. The general partner of TRV GP IV is TRV GP IV LLC. Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

SEC source: 0001192591-25-000008 · form4-10272025_081019.xml · nonDerivative · entry 1

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,624

F1 · kind: The reported transaction represents a gift, for no consideration, which is exempt pursuant to Rule 16b-5.

SEC source: 0001596492-25-000006 · form4-10072025_081023.xml · derivative · entry 1

Hoppenot Herve · CIK 0001596492 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2035-10-05

F1 · derivative.exercise_date: The option shall vest as to 1/36th of the total award monthly, with the first tranche vesting on November 6, 2025, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0002050422-25-000004 · form4-09242025_080910.xml · derivative · entry 1

Bachrodt Amy · CIK 0002050422 · SVP, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,000

Underlying: Common Stock · 22,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award shall vest as to 1/2 of the total award on September 1, 2026 and September 1, 2027, subject to the reporting person's continued service to the Issuer on each vesting date.

F3 · derivative.expiration_date: These restricted stock units do not expire; they either vest or are cancelled prior to the vesting date.

SEC source: 0002050172-25-000004 · form4-09242025_080911.xml · derivative · entry 1

Bernstein Harold · CIK 0002050172 · President, R&D & CMO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award shall vest as to 1/2 of the total award on September 1, 2026 and September 1, 2027, subject to the reporting person's continued service to the Issuer on each vesting date.

F3 · derivative.expiration_date: These restricted stock units do not expire; they either vest or are cancelled prior to the vesting date.

SEC source: 0002050167-25-000004 · form4-09242025_080950.xml · derivative · entry 1

Dandekar Atul · CIK 0002050167 · CSBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award shall vest as to 1/2 of the total award on September 1, 2026 and September 1, 2027, subject to the reporting person's continued service to the Issuer on each vesting date.

F3 · derivative.expiration_date: These restricted stock units do not expire; they either vest or are cancelled prior to the vesting date.

SEC source: 0001864112-25-000004 · form4-09242025_080928.xml · derivative · entry 1

Kathiresan Sekar · CIK 0001864112 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001804999-25-000005 · form4-09242025_080904.xml · derivative · entry 1

Andrews Nancy C · CIK 0001804999 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001620014-25-000005 · form4-09242025_080901.xml · derivative · entry 1

Exter Neil · CIK 0001620014 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001283290-25-000005 · form4-09242025_080917.xml · derivative · entry 1

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001238403-25-000005 · form4-09242025_080900.xml · derivative · entry 1

SPIEGELMAN DANIEL K · CIK 0001238403 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001192591-25-000005 · form4-09242025_080916.xml · derivative · entry 1

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001214133-25-000007 · form4-09242025_080927.xml · derivative · entry 1

SCHELLER RICHARD H · CIK 0001214133 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001555132-25-000005 · form4-09242025_080925.xml · derivative · entry 1

Sohn Catherine A. · CIK 0001555132 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2035-09-21

F1 · derivative.exercise_date: The option shall vest as to 1/9 of the total award monthly with the first tranche vesting on October 1, 2025, subject to the reporting person's continued service to the Issuer on the applicable vesting date.

SEC source: 0001676170-25-000008 · form4-09242025_080943.xml · derivative · entry 1

Coloma Jason V · CIK 0001676170 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award shall vest as to 1/2 of the total award on September 1, 2026 and September 1, 2027, subject to the reporting person's continued service to the Issuer on each vesting date.

F3 · derivative.expiration_date: These restricted stock units do not expire; they either vest or are cancelled prior to the vesting date.

SEC source: 0001782758-25-000005 · form4-09242025_080937.xml · derivative · entry 1

Courtney Phillips · CIK 0001782758 · GC and Corp. Secretary

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,000

Underlying: Common Stock · 22,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement.

F2 · derivative.exercise_date: The award shall vest as to 1/2 of the total award on September 1, 2026 and September 1, 2027, subject to the reporting person's continued service to the Issuer on each vesting date.

F3 · derivative.expiration_date: These restricted stock units do not expire; they either vest or are cancelled prior to the vesting date.

SEC source: 0001214133-25-000005 · form4-09162025_080924.xml · nonDerivative · entry 1

SCHELLER RICHARD H · CIK 0001214133 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.14 to $22.585, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001415889-25-023463 · form4-09022025_100947.xml · derivative · entry 1

Tahir Misbah · CIK 0001787359 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 325,000

Underlying: Common Stock · 325,000 shares

Expires 2035-09-01

F1 · derivative.exercise_date: The option shall vest as to 1/4th of the total award on September 2, 2026, and thereafter shall vest as to 1/48th of the total award on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-25-022301 · form4-08192025_080831.xml · derivative · entry 1

Exter Neil · CIK 0001620014 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2035-08-16

F1 · derivative.exercise_date: The option vested as to 1/16th of the total award on March 3, 2025, and thereafter vested or vests as to an additional 1/16th of the total award on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0000950170-25-013760 · ownership.xml · derivative · entry 5

Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner

Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner

TRV GP IV, LLC · CIK 0001688325 · 10% owner

Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner

Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner

TRV GP V, LLC · CIK 0001990717 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 0

Underlying: Common Stock · 950,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F3 · ownership.nature: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

SEC source: 0000950170-25-013760 · ownership.xml · derivative · entry 4

Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner

Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner

TRV GP IV, LLC · CIK 0001688325 · 10% owner

Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner

Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner

TRV GP V, LLC · CIK 0001990717 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,008,786 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F2 · ownership.direct: The shares are held directly by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

SEC source: 0000950170-25-013760 · ownership.xml · derivative · entry 3

Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner

Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner

TRV GP IV, LLC · CIK 0001688325 · 10% owner

Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner

Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner

TRV GP V, LLC · CIK 0001990717 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,754,002 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F2 · ownership.direct: The shares are held directly by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

SEC source: 0000950170-25-013760 · ownership.xml · nonDerivative · entry 2

Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner

Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner

TRV GP IV, LLC · CIK 0001688325 · 10% owner

Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner

Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner

TRV GP V, LLC · CIK 0001990717 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 950,800

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F3 · ownership.nature: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

SEC source: 0000950170-25-013760 · ownership.xml · nonDerivative · entry 1

Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner

Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner

TRV GP IV, LLC · CIK 0001688325 · 10% owner

Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner

Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner

TRV GP V, LLC · CIK 0001990717 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,073,958

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date.

F2 · ownership.direct: The shares are held directly by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · derivative · entry 5

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · City Hill, LLC

Disclosed balance after: 0

Underlying: Common Stock · 270,232 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for- 0.1211056427. The securities have no expiration date.

F3 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for- 0.1211056427. The securities have no expiration date.

F3 · derivative.exercise_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for- 0.1211056427. The securities have no expiration date.

F3 · derivative.expiration_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for- 0.1211056427. The securities have no expiration date.

F2 · ownership.nature: These securities are directly held by City Hill, LLC, of which the reporting person is the managing partner.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · derivative · entry 4

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · City Hill, LLC

Disclosed balance after: 0

Underlying: Common Stock · 37,724 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series A Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F1 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series A Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F1 · derivative.exercise_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series A Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F1 · derivative.expiration_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series A Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F2 · ownership.nature: These securities are directly held by City Hill, LLC, of which the reporting person is the managing partner.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · nonDerivative · entry 2

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · City Hill, LLC

Disclosed balance after: 307,956

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for- 0.1211056427. The securities have no expiration date.

F2 · ownership.nature: These securities are directly held by City Hill, LLC, of which the reporting person is the managing partner.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · nonDerivative · entry 1

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · City Hill, LLC

Disclosed balance after: 37,724

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series A Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F2 · ownership.nature: These securities are directly held by City Hill, LLC, of which the reporting person is the managing partner.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · derivative · entry 6

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Trust

Disclosed balance after: 0

Underlying: Common Stock · 7,422 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series D-1 Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F3 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series D-1 Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F3 · derivative.exercise_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series D-1 Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F3 · derivative.expiration_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series D-1 Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F4 · ownership.nature: These securities are directly held by the Charles J. Homcy Revocable Trust UA 11/4/1998 (the "Trust"), of which the reporting person is the trustee.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · derivative · entry 5

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,717 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series C Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1222996332. The securities have no expiration date.

F2 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series C Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1222996332. The securities have no expiration date.

F2 · derivative.exercise_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series C Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1222996332. The securities have no expiration date.

F2 · derivative.expiration_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series C Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1222996332. The securities have no expiration date.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · derivative · entry 4

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 8,807 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1211056427. The securities have no expiration date.

F1 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1211056427. The securities have no expiration date.

F1 · derivative.exercise_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1211056427. The securities have no expiration date.

F1 · derivative.expiration_date: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1211056427. The securities have no expiration date.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · nonDerivative · entry 3

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Trust

Disclosed balance after: 7,422

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series D-1 Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1037236801. The securities have no expiration date.

F4 · ownership.nature: These securities are directly held by the Charles J. Homcy Revocable Trust UA 11/4/1998 (the "Trust"), of which the reporting person is the trustee.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · nonDerivative · entry 2

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,047

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series C Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1222996332. The securities have no expiration date.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · nonDerivative · entry 1

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,330

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Pursuant to the Issuer's Restated Certificate of Incorporation, upon closing of the Issuer's initial public offering of its Common Stock, each share of Series B Convertible Preferred Stock automatically converted into shares of Common Stock at a ratio of 1-for-0.1211056427. The securities have no expiration date.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · derivative · entry 8

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,086

Underlying: Common Stock · 9,086 shares

Expires 2034-12-08

F4 · date: This transaction is an exempt transaction with the Issuer which occurred prior to the Issuer registering a class of equity securities under Section 12 of the Securities Exchange Act of 1934, as amended. It is reported herein as a transaction pursuant to Rule 16a-2(a). All numbers of shares and exercise prices have been adjusted to reflect a 1:9.641 reverse stock split of the Issuer's Common Stock effected on January 24, 2025.

F7 · derivative.exercise_date: The option vested or vests as to 1/36th of the total award monthly, with the first tranche vesting on January 1, 2025, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · derivative · entry 7

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,704 shares

Expires 2033-03-08

F4 · date: This transaction is an exempt transaction with the Issuer which occurred prior to the Issuer registering a class of equity securities under Section 12 of the Securities Exchange Act of 1934, as amended. It is reported herein as a transaction pursuant to Rule 16a-2(a). All numbers of shares and exercise prices have been adjusted to reflect a 1:9.641 reverse stock split of the Issuer's Common Stock effected on January 24, 2025.

F6 · price: This option, which was first granted on March 9, 2023, was canceled and exchanged for a new option having a lower exercise price in connection with an option repricing approved by the Issuer's Board of Directors on December 9, 2024. All terms of the option remained unchanged other than the exercise price.

F5 · derivative.exercise_date: The option vested or vests as to 1/36th of the total award monthly, with the first tranche vesting on April 1, 2023, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-25-002957 · form4-02042025_090248.xml · derivative · entry 6

Lim Jonathan E · CIK 0001283290 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,704

Underlying: Common Stock · 5,704 shares

Expires 2033-03-08

F4 · date: This transaction is an exempt transaction with the Issuer which occurred prior to the Issuer registering a class of equity securities under Section 12 of the Securities Exchange Act of 1934, as amended. It is reported herein as a transaction pursuant to Rule 16a-2(a). All numbers of shares and exercise prices have been adjusted to reflect a 1:9.641 reverse stock split of the Issuer's Common Stock effected on January 24, 2025.

F6 · price: This option, which was first granted on March 9, 2023, was canceled and exchanged for a new option having a lower exercise price in connection with an option repricing approved by the Issuer's Board of Directors on December 9, 2024. All terms of the option remained unchanged other than the exercise price.

F5 · derivative.exercise_date: The option vested or vests as to 1/36th of the total award monthly, with the first tranche vesting on April 1, 2023, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.

SEC source: 0001415889-25-002956 · form4-02042025_090216.xml · derivative · entry 15

HOMCY CHARLES J · CIK 0001192591 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,638

Underlying: Common Stock · 45,638 shares

Expires 2034-12-08

F6 · date: This transaction is an exempt transaction with the Issuer which occurred prior to the Issuer registering a class of equity securities under Section 12 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). It is reported herein as a transaction pursuant to Rule 16a-2(a). All numbers of shares and applicable security prices have been adjusted to reflect a 1:9.641 reverse stock split of the Issuer's Common Stock effected on January 24, 2025 and, where applicable, the conversion of the Issuer's series of Preferred Stock to Common Stock upon completion of its initial public offering.

F13 · derivative.exercise_date: The option vested or vests as to 1/36th of the total award monthly, with the first tranche vesting on January 1, 2025, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date.