organization · Reporting owner

Third Rock Ventures V, L.P.

Disclosed activity across 4 companies

Tapewire entity: 23357
SEC CIK: 0001778071

Reported relationships

Latest disclosed role at each company.

Company	Last reported as	Report date	Published
Maze Therapeutics, Inc.MAZE · Entity 1775	10% owner	November 04, 2025	November 05, 2025
Rapport Therapeutics, Inc.RAPP · Entity 4394	10% owner	May 26, 2026	May 28, 2026
Septerna, Inc.SEPN · Entity 2452	10% owner	August 12, 2026	August 14, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Maze Therapeutics, Inc.

Report date November 04, 2025 · Filed November 05, 2025

Jointly reported with Third Rock Ventures IV, L.P., Third Rock Ventures GP IV, L.P., TRV GP IV, LLC, Third Rock Ventures GP V, LP, TRV GP V, LLC

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	Direct	4,473,958	Reported balance After 2025-11-04 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes. 1 source row Row 1 · 2025-11-04 · Other · Disposed 1,600,000 · Balance 4,473,958 F1: On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended. F2: The shares are held directly by TRV IV. The general partner of TRV IV is TRV GP IV. The general partner of TRV GP IV is TRV GP IV LLC. Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.
Common StockSEC Table I · non-derivative	IndirectSee Footnotes	950,800	Reported balance Holding disclosure · report date 2025-11-04 · row 2 Holding and transaction disclosures are not merged. 1 source row Row 2 · Balance 950,800 F3: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Filing footnotes · ownership attribution and instrument terms

F1: On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended.

F2: The shares are held directly by TRV IV. The general partner of TRV IV is TRV GP IV. The general partner of TRV GP IV is TRV GP IV LLC. Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F3: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Rapport Therapeutics, Inc.

Report date May 26, 2026 · Filed May 28, 2026

Jointly reported with Third Rock Ventures GP V, LP, TRV GP V, LLC, Third Rock Ventures VI, L.P., Third Rock Ventures GP VI, L.P., TRV GP VI, LLC

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	Direct	6,280,525	Reported balance After 2026-05-26 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes. 1 source row Row 1 · 2026-05-26 · Sale · Disposed 18,572 · Balance 6,280,525 F1: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person. F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.
Common StockSEC Table I · non-derivative	IndirectBy Third Rock Ventures VI, L.P.	969,218	Reported balance Holding disclosure · report date 2026-05-26 · row 2 Holding and transaction disclosures are not merged. 1 source row Row 2 · Balance 969,218 F4: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between any TRV V related parties and any TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Filing footnotes · ownership attribution and instrument terms

F1: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2).

F3: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.

F4: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between any TRV V related parties and any TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Septerna, Inc.

Report date August 12, 2026 · Filed August 14, 2026

Jointly reported with Third Rock Ventures GP V, LP, TRV GP V, LLC, Third Rock Ventures VI, L.P., Third Rock Ventures GP VI, L.P., TRV GP VI, LLC

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	Direct	6,068,532	Reported balance After 2026-08-12 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes. 1 source row Row 1 · 2026-08-12 · Sale · Acquired 147,059 · Balance 6,068,532 F1: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 26, 2026, previously adopted by the Reporting Person. F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.05 to $50.81, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.
Common StockSEC Table I · non-derivative	Direct	6,068,391	Reported balance After 2026-08-12 transaction · row 2 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes. 1 source row Row 2 · 2026-08-12 · Sale · Acquired 141 · Balance 6,068,391 F1: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 26, 2026, previously adopted by the Reporting Person. F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.00 to $51.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4). F3: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.
Common StockSEC Table I · non-derivative	IndirectBy Third Rock Ventures VI, L.P.	4,211,659	Reported balance Holding disclosure · report date 2026-08-12 · row 3 Holding and transaction disclosures are not merged. 1 source row Row 3 · Balance 4,211,659 F5: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between any TRV V related parties and any TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Filing footnotes · ownership attribution and instrument terms

F1: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 26, 2026, previously adopted by the Reporting Person.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.05 to $50.81, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2).

F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.00 to $51.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4).

F5: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between any TRV V related parties and any TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

CARGO Therapeutics, Inc.

Report date November 14, 2023 · Filed November 15, 2023

Jointly reported with Third Rock Ventures GP V, LP, TRV GP V, LLC, Third Rock Ventures VI, L.P., Third Rock Ventures GP VI, L.P., TRV GP VI, LLC

Section 16 reporting ended · disclosed 2023-11-15. Current position is not established by this disclosure.

Security / award	Ownership account	Disclosed shares / units	Disclosure context
Common StockSEC Table I · non-derivative	Direct	1,737,216	Reported balance After 2023-11-14 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes. 1 source row Row 1 · 2023-11-14 · Conversion · Acquired 1,737,216 · Balance 1,737,216 F1: Represents the total number of shares of Common Stock received by Third Rock Ventures V, L.P. ("TRV V") upon conversion of the preferred stock of the Issuer in connection with the closing of the Issuer's initial public offering. F2: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F3: These shares are directly held by TRV V. F4: The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of these shares except to the extent of its or his pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.
Common StockSEC Table I · non-derivative	IndirectSee Footnotes	1,807,119	Last balance in matching sequence After 2023-11-14 transaction · row 3 Source-order balances reconcile. Account continuity and personal attribution are not independently verified. 2 source rows Row 2 · 2023-11-14 · Conversion · Acquired 473,786 · Balance 473,786 F5: Represents the total number of shares of Common Stock received by Third Rock Ventures VI, L.P. ("TRV VI") upon conversion of the preferred stock of the Issuer in connection with the closing of the Issuer's initial public offering. F2: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F6: These shares are directly held by TRV VI. F7: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Row 3 · 2023-11-14 · Purchase · Acquired 1,333,333 · Balance 1,807,119 F6: These shares are directly held by TRV VI. F7: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.
Series A-1 Preferred StockSEC Table II · derivative / convertible security	Direct	0	Reported balance After 2023-11-14 transaction · row 4 Instrument identity requires review; Table II rows are not merged. 1 source row Row 4 · 2023-11-14 · Conversion · Disposed 23,571,429 · Balance 0 F2: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F3: These shares are directly held by TRV V. F4: The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of these shares except to the extent of its or his pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.
Series A-1 Preferred StockSEC Table II · derivative / convertible security	IndirectSee Footnotes	0	Reported balance After 2023-11-14 transaction · row 5 Instrument identity requires review; Table II rows are not merged. 1 source row Row 5 · 2023-11-14 · Conversion · Disposed 6,428,571 · Balance 0 F2: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F6: These shares are directly held by TRV VI. F7: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Filing footnotes · ownership attribution and instrument terms

F1: Represents the total number of shares of Common Stock received by Third Rock Ventures V, L.P. ("TRV V") upon conversion of the preferred stock of the Issuer in connection with the closing of the Issuer's initial public offering.

F2: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date.

F3: These shares are directly held by TRV V.

F4: The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of these shares except to the extent of its or his pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares.

F5: Represents the total number of shares of Common Stock received by Third Rock Ventures VI, L.P. ("TRV VI") upon conversion of the preferred stock of the Issuer in connection with the closing of the Issuer's initial public offering.

F6: These shares are directly held by TRV VI.

F7: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares.

F8: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties.

Transaction history

JSON API

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction date	Company	Activity / security	Shares / units	Reported price	Reported value	Details
August 12, 2026 Filed Aug 14, 2026 21:44 UTC	Septerna, Inc. SEPN · Entity 2452	SaleCommon Stock	141	$51.08	$7,202.28	Disclosure SEC source: 0001193125-26-352692 · ownership.xml · nonDerivative · entry 2 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,068,391 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 26, 2026, previously adopted by the Reporting Person. F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.00 to $51.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
August 12, 2026 Filed Aug 14, 2026 21:44 UTC	Septerna, Inc. SEPN · Entity 2452	SaleCommon Stock	147,059	$50.27	$7,392,655.93	Disclosure SEC source: 0001193125-26-352692 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,068,532 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated March 26, 2026, previously adopted by the Reporting Person. F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.05 to $50.81, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
May 26, 2026 Filed May 28, 2026 20:15 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	SaleCommon Stock	18,572	$40.05	$743,752.88	Disclosure SEC source: 0001193125-26-245259 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,280,525 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person. F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.10, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
May 11, 2026 Filed May 13, 2026 23:06 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	SaleCommon Stock	133,618	$40.24	$5,377,322.79	Disclosure SEC source: 0001193125-26-222185 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,299,097 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person. F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.665, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
May 08, 2026 Filed May 11, 2026 21:07 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	SaleCommon Stock	5,018	$40.31	$202,255.51	Disclosure SEC source: 0001193125-26-217092 · ownership.xml · nonDerivative · entry 2 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,432,715 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person. F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.10 to $40.80, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (4). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
May 07, 2026 Filed May 11, 2026 21:07 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	SaleCommon Stock	271,495	$40.12	$10,892,650.90	Disclosure SEC source: 0001193125-26-217092 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,437,733 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person. F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.60, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
April 17, 2026 Filed Apr 21, 2026 23:36 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	SaleCommon Stock	426,005	$40.32	$17,175,243.59	Disclosure SEC source: 0001193125-26-167636 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 6,709,228 F1 · kind: The reported transactions were effected pursuant to a Rule 10b5-1 trading plan dated November 21, 2025, previously adopted by the Reporting Person. F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $40.00 to $40.79, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (2). F3 · ownership.direct: These shares are directly held by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. Read SEC document
November 04, 2025 Filed Nov 5, 2025 21:15 UTC	Maze Therapeutics, Inc. MAZE · Entity 1775	OtherCommon Stock	1,600,000	Not disclosed	Not disclosed	Disclosure SEC source: 0001193125-25-266981 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner TRV GP IV, LLC · CIK 0001688325 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 4,473,958 F1 · kind: On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended. F1 · price: On November 4, 2025, Third Rock Ventures IV, L.P. ("TRV IV ") distributed, for no consideration, 1,600,000 shares of Common Stock of the Issuer (the "Shares") to its limited partners and to Third Rock Ventures GP IV, L.P. ("TRV GP IV "), the general partner of TRV IV, representing each such partner's pro rata interest in such Shares. On the same date, TRV GP IV distributed, for no consideration, the Shares it received in the distribution by TRV IV to its partners, representing each such partner's pro rata interest in such Shares. All of the aforementioned distributions were made in accordance with the exemptions afforded by Rules 16a-13 and 16a-9 of the Securities Exchange Act of 1934, as amended. F2 · ownership.direct: The shares are held directly by TRV IV. The general partner of TRV IV is TRV GP IV. The general partner of TRV GP IV is TRV GP IV LLC. Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 24, 2025 Filed Feb 26, 2025 21:15 UTC	Septerna, Inc. SEPN · Entity 2452	PurchaseCommon Stock	18,861	$6.00	$113,147.14	Disclosure SEC source: 0000950170-25-027754 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 4,211,659 F1 · price: The price reported in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $5.975 to $6.00, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price at which the transactions were effected. F2 · ownership.direct: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 21, 2025 Filed Feb 24, 2025 21:15 UTC	Septerna, Inc. SEPN · Entity 2452	PurchaseCommon Stock	427,668	$5.94	$2,540,347.92	Disclosure SEC source: 0000950170-25-025631 · ownership.xml · nonDerivative · entry 2 Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 4,192,798 F3 · price: The price reported in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $5.67 to $6.00, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price at which the transactions were effected. F2 · ownership.direct: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F5 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 20, 2025 Filed Feb 24, 2025 21:15 UTC	Septerna, Inc. SEPN · Entity 2452	PurchaseCommon Stock	612,674	$5.92	$3,627,030.08	Disclosure SEC source: 0000950170-25-025631 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 3,765,130 F1 · price: The price reported in Column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $5.39 to $6.00, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price at which the transactions were effected. F2 · ownership.direct: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F5 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 03, 2025 Filed Feb 4, 2025 22:31 UTC	Maze Therapeutics, Inc. MAZE · Entity 1775	ConversionSeries A Preferred Stock · Derivative	9,166,666	$0.00	$0.00	Disclosure SEC source: 0000950170-25-013760 · ownership.xml · derivative · entry 5 Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner TRV GP IV, LLC · CIK 0001688325 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 0 Underlying: Common Stock · 950,800 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 03, 2025 Filed Feb 4, 2025 22:31 UTC	Maze Therapeutics, Inc. MAZE · Entity 1775	ConversionSeries D-1 Preferred Stock · Derivative	9,725,709	$0.00	$0.00	Disclosure SEC source: 0000950170-25-013760 · ownership.xml · derivative · entry 4 Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner TRV GP IV, LLC · CIK 0001688325 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 1,008,786 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 03, 2025 Filed Feb 4, 2025 22:31 UTC	Maze Therapeutics, Inc. MAZE · Entity 1775	ConversionSeries A Preferred Stock · Derivative	45,833,334	$0.00	$0.00	Disclosure SEC source: 0000950170-25-013760 · ownership.xml · derivative · entry 3 Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner TRV GP IV, LLC · CIK 0001688325 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 4,754,002 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 03, 2025 Filed Feb 4, 2025 22:31 UTC	Maze Therapeutics, Inc. MAZE · Entity 1775	ConversionCommon Stock	950,800	$0.00	$0.00	Disclosure SEC source: 0000950170-25-013760 · ownership.xml · nonDerivative · entry 2 Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner TRV GP IV, LLC · CIK 0001688325 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 950,800 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
February 03, 2025 Filed Feb 4, 2025 22:31 UTC	Maze Therapeutics, Inc. MAZE · Entity 1775	ConversionCommon Stock	5,762,788	$0.00	$0.00	Disclosure SEC source: 0000950170-25-013760 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures IV, L.P. · CIK 0001688327 · 10% owner Third Rock Ventures GP IV, L.P. · CIK 0001688326 · 10% owner TRV GP IV, LLC · CIK 0001688325 · 10% owner Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 6,073,958 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series D-1 Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-0.1037 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV, and TRV GP IV LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV IV related parties and the TRV V related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
October 28, 2024 Filed Oct 28, 2024 20:53 UTC	Septerna, Inc. SEPN · Entity 2452	ConversionSeries B Preferred Stock · Derivative	24,737,017	$0.00	$0.00	Disclosure SEC source: 0000950170-24-117772 · ownership.xml · derivative · entry 6 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 0 Underlying: Common Stock · 2,872,956 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
October 28, 2024 Filed Oct 28, 2024 20:53 UTC	Septerna, Inc. SEPN · Entity 2452	ConversionSeries A Preferred Stock · Derivative	41,250,000	$0.00	$0.00	Disclosure SEC source: 0000950170-24-117772 · ownership.xml · derivative · entry 5 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 4,790,773 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
October 28, 2024 Filed Oct 28, 2024 20:53 UTC	Septerna, Inc. SEPN · Entity 2452	PurchaseCommon Stock	279,500	$18.00	$5,031,000.00	Disclosure SEC source: 0000950170-24-117772 · ownership.xml · nonDerivative · entry 4 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 3,152,456 F3 · ownership.nature: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
October 28, 2024 Filed Oct 28, 2024 20:53 UTC	Septerna, Inc. SEPN · Entity 2452	PurchaseCommon Stock	370,500	$18.00	$6,669,000.00	Disclosure SEC source: 0000950170-24-117772 · ownership.xml · nonDerivative · entry 3 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 6,215,591 F2 · ownership.direct: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
October 28, 2024 Filed Oct 28, 2024 20:53 UTC	Septerna, Inc. SEPN · Entity 2452	ConversionCommon Stock	2,872,956	$0.00	$0.00	Disclosure SEC source: 0000950170-24-117772 · ownership.xml · nonDerivative · entry 2 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 2,872,956 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
October 28, 2024 Filed Oct 28, 2024 20:53 UTC	Septerna, Inc. SEPN · Entity 2452	ConversionCommon Stock	4,790,773	$0.00	$0.00	Disclosure SEC source: 0000950170-24-117772 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 5,845,091 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.6103 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
June 10, 2024 Filed Jun 10, 2024 23:42 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	ConversionSeries B Preferred Stock · Derivative	298,103	$0.00	$0.00	Disclosure SEC source: 0000950170-24-071537 · ownership.xml · derivative · entry 5 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By Third Rock Ventures VI, L.P. Disclosed balance after: 0 Underlying: Common Stock · 34,818 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV III related parties and the TRV IV related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
June 10, 2024 Filed Jun 10, 2024 23:42 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	ConversionSeries A Preferred Stock · Derivative	8,000,000	$0.00	$0.00	Disclosure SEC source: 0000950170-24-071537 · ownership.xml · derivative · entry 4 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By Third Rock Ventures VI, L.P. Disclosed balance after: 0 Underlying: Common Stock · 934,400 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV III related parties and the TRV IV related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
June 10, 2024 Filed Jun 10, 2024 23:42 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	ConversionSeries A Preferred Stock · Derivative	56,091,177	$0.00	$0.00	Disclosure SEC source: 0000950170-24-071537 · ownership.xml · derivative · entry 3 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 6,551,449 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV III related parties and the TRV IV related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
June 10, 2024 Filed Jun 10, 2024 23:42 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	ConversionCommon Stock	969,218	$0.00	$0.00	Disclosure SEC source: 0000950170-24-071537 · ownership.xml · nonDerivative · entry 2 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · By Third Rock Ventures VI, L.P. Disclosed balance after: 969,218 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F3 · ownership.nature: The shares are held directly by Third Rock Ventures VI, L.P. ("TRV VI"). The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI, and TRV GP VI LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV III related parties and the TRV IV related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
June 10, 2024 Filed Jun 10, 2024 23:42 UTC	Rapport Therapeutics, Inc. RAPP · Entity 4394	ConversionCommon Stock	6,551,449	$0.00	$0.00	Disclosure SEC source: 0000950170-24-071537 · ownership.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 7,135,233 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: Upon the closing of the Issuer's initial public offering, each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") automatically converted into Common Stock on a one-for-8.5648 basis without payment of consideration. The Preferred Stock had no expiration date. F2 · ownership.direct: The shares are held directly by Third Rock Ventures V, L.P. ("TRV V"). The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V, and TRV GP V LLC, disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares. F4 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV III related parties and the TRV IV related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
November 14, 2023 Filed Nov 15, 2023 00:08 UTC	CARGO Therapeutics, Inc. CRGX · Entity 76319	ConversionSeries A-1 Preferred Stock · Derivative	6,428,571	$0.00	$0.00	Disclosure SEC source: 0000899243-23-020350 · doc4.xml · derivative · entry 5 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 0 Underlying: Common Stock · 473,786 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F2 · derivative.exercise_date: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F2 · derivative.expiration_date: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F6 · ownership.nature: These shares are directly held by TRV VI. F7 · ownership.nature: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
November 14, 2023 Filed Nov 15, 2023 00:08 UTC	CARGO Therapeutics, Inc. CRGX · Entity 76319	ConversionSeries A-1 Preferred Stock · Derivative	23,571,429	$0.00	$0.00	Disclosure SEC source: 0000899243-23-020350 · doc4.xml · derivative · entry 4 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 1,737,216 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_price: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F2 · derivative.exercise_date: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F2 · derivative.expiration_date: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F3 · ownership.direct: These shares are directly held by TRV V. F4 · ownership.direct: The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of these shares except to the extent of its or his pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
November 14, 2023 Filed Nov 15, 2023 00:08 UTC	CARGO Therapeutics, Inc. CRGX · Entity 76319	PurchaseCommon Stock	1,333,333	$15.00	$19,999,995.00	Disclosure SEC source: 0000899243-23-020350 · doc4.xml · nonDerivative · entry 3 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 1,807,119 F6 · ownership.nature: These shares are directly held by TRV VI. F7 · ownership.nature: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
November 14, 2023 Filed Nov 15, 2023 00:08 UTC	CARGO Therapeutics, Inc. CRGX · Entity 76319	ConversionCommon Stock	473,786	Not disclosed	Not disclosed	Disclosure SEC source: 0000899243-23-020350 · doc4.xml · nonDerivative · entry 2 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Indirect · See Footnotes Disclosed balance after: 473,786 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · shares: Represents the total number of shares of Common Stock received by Third Rock Ventures VI, L.P. ("TRV VI") upon conversion of the preferred stock of the Issuer in connection with the closing of the Issuer's initial public offering. F2 · price: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F6 · ownership.nature: These shares are directly held by TRV VI. F7 · ownership.nature: The general partner of TRV VI is Third Rock Ventures GP VI, L.P. ("TRV GP VI"). The general partner of TRV GP VI is TRV GP VI, LLC ("TRV GP VI LLC"). Each of TRV GP VI and TRV GP VI LLC disclaims beneficial ownership of these shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8 · ownership.nature: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document
November 14, 2023 Filed Nov 15, 2023 00:08 UTC	CARGO Therapeutics, Inc. CRGX · Entity 76319	ConversionCommon Stock	1,737,216	Not disclosed	Not disclosed	Disclosure SEC source: 0000899243-23-020350 · doc4.xml · nonDerivative · entry 1 Third Rock Ventures V, L.P. · CIK 0001778071 · 10% owner Third Rock Ventures GP V, LP · CIK 0001977498 · 10% owner TRV GP V, LLC · CIK 0001990717 · 10% owner Third Rock Ventures VI, L.P. · CIK 0001931056 · 10% owner Third Rock Ventures GP VI, L.P. · CIK 0001977499 · 10% owner TRV GP VI, LLC · CIK 0001990716 · 10% owner Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,737,216 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · shares: Represents the total number of shares of Common Stock received by Third Rock Ventures V, L.P. ("TRV V") upon conversion of the preferred stock of the Issuer in connection with the closing of the Issuer's initial public offering. F2 · price: The Series A-1 Preferred Stock converted into Common Stock on a 13.5685-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A-1 Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The Series A-1 Preferred Stock had no expiration date. F3 · ownership.direct: These shares are directly held by TRV V. F4 · ownership.direct: The general partner of TRV V is Third Rock Ventures GP V, L.P. ("TRV GP V"). The general partner of TRV GP V is TRV GP V, LLC ("TRV GP V LLC"). Each of TRV GP V and TRV GP V LLC disclaims beneficial ownership of these shares except to the extent of its or his pecuniary interest therein, if any, and this report shall not be deemed an admission that it or he is the beneficial owner of such shares. F8 · ownership.direct: Each of Reporting Persons disclaims the existence of a Section 13(d) "group" as between the TRV V related parties and the TRV VI related parties and this report shall not be deemed an admission that any of such parties is or may be part of such a group with any of the other parties. Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.