INSM

SEC source: 0001140361-21-017901 · form4.xml · nonDerivative · entry 1

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,204

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001140361-21-017898 · form4.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 110,247

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001140361-21-017895 · form4.xml · nonDerivative · entry 1

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,985

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001140361-21-017891 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,792

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001140361-21-017888 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 201,471

F1 · shares: Shares withheld by the Company to satisfy tax withholding requirements on vesting of time-based restricted stock units.

SEC source: 0001140361-21-017469 · form4.xml · derivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,640

Underlying: Common Stock · 68,640 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017469 · form4.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 112,724

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017464 · form4.xml · derivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,640

Underlying: Common Stock · 68,640 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017464 · form4.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,355

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017462 · form4.xml · derivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,640

Underlying: Common Stock · 68,640 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017462 · form4.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,768

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017456 · form4.xml · derivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 137,280

Underlying: Common Stock · 137,280 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017456 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 207,952

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017450 · form4.xml · derivative · entry 2

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,200

Underlying: Common Stock · 57,200 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017450 · form4.xml · nonDerivative · entry 1

Pellizzari Christine A · CIK 0001127430 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,531

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017444 · form4.xml · derivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,760

Underlying: Common Stock · 45,760 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017444 · form4.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,598

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017440 · form4.xml · derivative · entry 2

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,320

Underlying: Common Stock · 34,320 shares

Expires 2031-05-12

F3 · derivative.exercise_date: Stock options granted under the Company's 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-017440 · form4.xml · nonDerivative · entry 1

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,859

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017430 · form4.xml · nonDerivative · entry 1

ENGELSEN STEINAR J · CIK 0001218860 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 306,567

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017428 · form4.xml · nonDerivative · entry 1

LEE LEO · CIK 0001740789 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,620

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017425 · form4.xml · nonDerivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,916

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017421 · form4.xml · nonDerivative · entry 1

SCHAFER CAROL · CIK 0001272181 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,260

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017419 · form4.xml · nonDerivative · entry 1

ANDERSON ELIZABETH M · CIK 0001758247 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,672

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017417 · form4.xml · nonDerivative · entry 1

Brennan David R · CIK 0001609305 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,876

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017415 · form4.xml · nonDerivative · entry 1

Desjardins Clarissa · CIK 0001793390 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,950

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-017413 · form4.xml · nonDerivative · entry 1

ALTOMARI ALFRED · CIK 0001285644 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,496

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of vesting date.

F2 · price: Each Restricted Stock Unit was granted on May 12, 2021, for no consideration.

SEC source: 0001140361-21-017411 · form4.xml · nonDerivative · entry 8

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 236,876

F5 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock. The Restricted Stock Units have a one year cliff vesting period, provided that the director (a) remains a member of the Board on such vesting date, and (b) attends at least 75% of the meetings of the Board which take place between the grant date and the first anniversary of the grant date. Vested shares are delivered within 30 days of the vesting date.

F6 · price: Each Restricted Stock Unit was granted on May 12, 2021 for no consideration.

SEC source: 0001140361-21-009085 · form4.xml · derivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 130,630

Underlying: Common Stock · 50,000 shares

Expires 2022-09-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-009085 · form4.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 179,608

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 300 shares sold at prices ranging from $37.05 to $37.25 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-009085 · form4.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 179,908

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 26,061 shares sold at prices ranging from $36.15 to $37.04 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-009085 · form4.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 205,969

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 23,639 shares sold at prices ranging from $35.18 to $36.13 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-009085 · form4.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 229,608

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001140361-21-008324 · form4.xml · derivative · entry 3

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,550

Underlying: Common Stock · 23,717 shares

Expires 2028-01-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-008324 · form4.xml · nonDerivative · entry 2

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,773

F1 · price: This is the weighted average sales price representing the shares sold at prices ranging from $40.00 to $40.01 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-008324 · form4.xml · nonDerivative · entry 1

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,490

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-008183 · form4.xml · derivative · entry 12

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,267

Underlying: Common Stock · 500 shares

Expires 2028-01-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 8

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,773

F2 · price: This is the weighted average sales price representing the shares sold at prices ranging from $40.00 to $40.01 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 7

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,273

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-008183 · form4.xml · derivative · entry 11

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,390

Underlying: Common Stock · 14,130 shares

Expires 2030-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-008183 · form4.xml · derivative · entry 10

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,395

Underlying: Common Stock · 17,349 shares

Expires 2029-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-008183 · form4.xml · derivative · entry 9

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,767

Underlying: Common Stock · 13,433 shares

Expires 2028-01-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 6

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,773

F1 · price: This is the weighted average sales price representing the shares sold at prices ranging from $40.00 to $40.61 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 5

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,903

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 4

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,773

F1 · price: This is the weighted average sales price representing the shares sold at prices ranging from $40.00 to $40.61 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 3

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,122

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 2

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,773

F1 · price: This is the weighted average sales price representing the shares sold at prices ranging from $40.00 to $40.61 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001140361-21-008183 · form4.xml · nonDerivative · entry 1

SORIANO JOHN · CIK 0001740947 · Chief Compliance Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,206

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-21-008313 · form4.xml · derivative · entry 3

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,791

Underlying: Common Stock · 4,709 shares

Expires 2024-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Stock options granted under the Company's 2013 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001140361-21-008313 · form4.xml · nonDerivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,150