INSM

SEC source: 0001628280-25-029406 · wk-form4_1749073009.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 141,323

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-25-029405 · wk-form4_1749072980.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 113,288

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-25-029372 · wk-form4_1749069723.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 118,579

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-25-029368 · wk-form4_1749069612.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 308,758

F5 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-25-029370 · wk-form4_1749069680.xml · nonDerivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 100,723

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 3,250 shares sold at prices ranging from $71.09 to $71.54 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-029368 · wk-form4_1749069612.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 157,160

Underlying: Common Stock · 6,830 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 12, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

SEC source: 0001628280-25-029368 · wk-form4_1749069612.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 12, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 1,430 shares sold at prices ranging from $71.67 to $72.24 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-029368 · wk-form4_1749069612.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 235,354

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 12, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 4,400 shares sold at prices ranging from $70.67 to $71.66 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-029368 · wk-form4_1749069612.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 239,754

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 12, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 1,000 shares sold at prices ranging from $69.59 to $70.57 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-029368 · wk-form4_1749069612.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 12, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-25-029012 · wk-form4_1748980929.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,045

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 20,000 shares sold at prices ranging from $70.00 to $70.04 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-029012 · wk-form4_1748980929.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 91,045

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 6,327 shares sold at prices ranging from $68.13 to $68.88 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-028379 · wk-form4_1748551609.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,616

SEC source: 0001628280-25-027340 · wk-form4_1747948827.xml · nonDerivative · entry 2

Desjardins Clarissa · CIK 0001793390 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By spouse

Disclosed balance after: 3,025

SEC source: 0001628280-25-027344 · wk-form4_1747948965.xml · nonDerivative · entry 5

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Melvin Sharoky C/F Wren J. Sharoky UTMA/FL

Disclosed balance after: 100

F4 · ownership.nature: The Reporting Person is the custodian of Melvin Sharoky C/F Wren J. Sharoky UTMA/FL.

SEC source: 0001628280-25-027344 · wk-form4_1747948965.xml · nonDerivative · entry 4

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Melvin Sharoky C/F Leo J. Sharoky UTMA/FL

Disclosed balance after: 100

F3 · ownership.nature: The Reporting Person is the custodian of Melvin Sharoky C/F Leo J. Sharoky UTMA/FL.

SEC source: 0001628280-25-027344 · wk-form4_1747948965.xml · nonDerivative · entry 3

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Melvin Sharoky C/F Violet A. Paley UTMA/FL

Disclosed balance after: 100

F2 · ownership.nature: The Reporting Person is the custodian of Melvin Sharoky C/F Violet A. Paley UTMA/FL.

SEC source: 0001628280-25-027344 · wk-form4_1747948965.xml · nonDerivative · entry 2

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Melvin Sharoky C/F Owen F. Paley UTMA/FL

Disclosed balance after: 100

F1 · ownership.nature: The Reporting Person is the custodian of Melvin Sharoky C/F Owen F. Paley UTMA/FL.

SEC source: 0001628280-25-027344 · wk-form4_1747948965.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,816

SEC source: 0001628280-25-027340 · wk-form4_1747948827.xml · nonDerivative · entry 1

Desjardins Clarissa · CIK 0001793390 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By spouse

Disclosed balance after: 1,895

F1 · price: This is the weighted average purchase price representing 1,895 shares purchased at prices ranging from $66.75 to $66.98 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares purchased at each price within the price range upon request.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · derivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 163,990

Underlying: Common Stock · 6,830 shares

Expires 2026-05-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 1,716 shares sold at prices ranging from $68.50 to $68.59 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 235,640

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 2,251 shares sold at prices ranging from $67.49 to $68.47 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 237,891

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,863 shares sold at prices ranging from $66.42 to $67.35 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By the Katie Procter Dynasty Trust

Disclosed balance after: 240,754

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 314,230

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 7,088 shares sold at prices ranging from $68.38 to $68.59 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 321,318

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 4,480 shares sold at prices ranging from $67.38 to $68.37 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-027339 · wk-form4_1747948703.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 325,798

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 9,489 shares sold at prices ranging from $66.34 to $67.32 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-026581 · wk-form4_1747688735.xml · nonDerivative · entry 3

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 84,797

F3 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-25-026586 · wk-form4_1747688783.xml · derivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,610

Underlying: Common Stock · 31,610 shares

Expires 2035-05-15

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

SEC source: 0001628280-25-026586 · wk-form4_1747688783.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 114,867

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026585 · wk-form4_1747688771.xml · derivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,610

Underlying: Common Stock · 31,610 shares

Expires 2035-05-15

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

SEC source: 0001628280-25-026585 · wk-form4_1747688771.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 143,183

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026584 · wk-form4_1747688760.xml · derivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,100

Underlying: Common Stock · 27,100 shares

Expires 2035-05-15

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

SEC source: 0001628280-25-026584 · wk-form4_1747688760.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,221

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026583 · wk-form4_1747688749.xml · derivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,380

Underlying: Common Stock · 108,380 shares

Expires 2035-05-15

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

SEC source: 0001628280-25-026583 · wk-form4_1747688749.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 335,287

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026581 · wk-form4_1747688735.xml · derivative · entry 4

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,610

Underlying: Common Stock · 31,610 shares

Expires 2035-05-15

F5 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

SEC source: 0001628280-25-026581 · wk-form4_1747688735.xml · nonDerivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 86,596

F3 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 9,925 shares sold at prices ranging from $65.32 to $65.99 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-25-026581 · wk-form4_1747688735.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 96,521

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026580 · wk-form4_1747688723.xml · derivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,100

Underlying: Common Stock · 27,100 shares

Expires 2035-05-15

F3 · derivative.exercise_date: These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

SEC source: 0001628280-25-026580 · wk-form4_1747688723.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 97,372

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026569 · wk-form4_1747688264.xml · nonDerivative · entry 1

Brennan David R · CIK 0001609305 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,933

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026568 · wk-form4_1747688254.xml · nonDerivative · entry 1

SCHAFER CAROL · CIK 0001272181 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,317

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026567 · wk-form4_1747688244.xml · nonDerivative · entry 1

Desjardins Clarissa · CIK 0001793390 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,007

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026566 · wk-form4_1747688232.xml · nonDerivative · entry 1

SHAROKY MELVIN MD · CIK 0001182633 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 301,216

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026565 · wk-form4_1747688222.xml · nonDerivative · entry 1

ANDERSON ELIZABETH M · CIK 0001758247 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 73,729

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026564 · wk-form4_1747688210.xml · nonDerivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 103,973

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-026563 · wk-form4_1747688199.xml · nonDerivative · entry 1

LEE LEO · CIK 0001740789 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 129,677

F1 · shares: Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock. The RSUs have a one year cliff vesting period, provided that the director (a) remains a member of the Board of Directors of the issuer on such vesting date, and (b) attends at least 75% of the meetings of the Board of Directors which take place between the grant date and the first anniversary of the grant date.

F2 · price: Each RSU was granted on May 15, 2025 for no consideration.

SEC source: 0001628280-25-025995 · wk-form4_1747341358.xml · nonDerivative · entry 2

Smith Michael Alexander · CIK 0001870278 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,794

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.