GLUE

SEC source: 0000950170-25-081637 · ownership.xml · nonDerivative · entry 1

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,732

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.34 to $4.45, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-25-044633 · ownership.xml · nonDerivative · entry 1

Leo Chandra P. · CIK 0001855642 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

SEC source: 0000950170-25-002101 · ownership.xml · derivative · entry 2

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 135,000

Underlying: Common Stock · 135,000 shares

Expires 2035-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2026, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002101 · ownership.xml · nonDerivative · entry 1

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

F1 · shares: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F1 · price: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002103 · ownership.xml · derivative · entry 2

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,400

Underlying: Common Stock · 53,400 shares

Expires 2035-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2026, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002103 · ownership.xml · nonDerivative · entry 1

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,794

F1 · shares: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F1 · price: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002102 · ownership.xml · derivative · entry 2

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 161,000

Underlying: Common Stock · 161,000 shares

Expires 2035-01-01

F3 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2026, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002102 · ownership.xml · nonDerivative · entry 1

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,189

F1 · shares: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F1 · price: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F2 · balance_after: Includes 3,937 shares acquired under the Issuer's 2021 Employee Stock Purchase Program on June 28, 2024.

SEC source: 0000950170-25-002100 · ownership.xml · derivative · entry 2

Warmuth Markus · CIK 0001855643 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 575,000

Underlying: Common Stock · 575,000 shares

Expires 2035-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2026, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002100 · ownership.xml · nonDerivative · entry 1

Warmuth Markus · CIK 0001855643 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 544,538

F1 · shares: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F1 · price: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002099 · ownership.xml · derivative · entry 2

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 161,000

Underlying: Common Stock · 161,000 shares

Expires 2035-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2026, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002099 · ownership.xml · nonDerivative · entry 1

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

F1 · shares: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F1 · price: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002105 · ownership.xml · derivative · entry 2

Nickson Philip · CIK 0001911369 · Chief Business & Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 161,000

Underlying: Common Stock · 161,000 shares

Expires 2035-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2026, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-002105 · ownership.xml · nonDerivative · entry 1

Nickson Philip · CIK 0001911369 · Chief Business & Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

F1 · shares: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

F1 · price: Represents restricted stock units ("RSUs") granted under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the contingent right to receive one share of the Issuer's Common Stock upon vesting and settlement. 25% of the RSUs shall vest on January 1, 2026, with the remainder vesting in 3 equal annual installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-136056 · ownership.xml · derivative · entry 1

Hughes Eric A · CIK 0001938678 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,200

Underlying: Common Stock · 44,200 shares

Expires 2034-12-10

F1 · derivative.exercise_date: This option shall vest and become exercisable in 36 substantially equal monthly installments following the grant date, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 13

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,573,453

F19 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $9.33 to $9.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (19) to this Form 4.

F2 · ownership.nature: Shares held by Versant Vantage I, L.P. ("Versant Vantage I"). Versant Vantage I GP, L.P. ("Versant Vantage I GP") is the general partner of Versant Vantage I, and Versant Vantage I GP-GP, LLC ("Versant Vantage I GP-GP") is the general partner of Versant Vantage I GP. Each of Versant Vantage I GP-GP and Versant Vantage I GP may be deemed to share voting, investment and dispositive power over the shares held by Versant Vantage I and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 12

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,589,053

F18 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $8.36 to $9.32, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (18) to this Form 4.

F2 · ownership.nature: Shares held by Versant Vantage I, L.P. ("Versant Vantage I"). Versant Vantage I GP, L.P. ("Versant Vantage I GP") is the general partner of Versant Vantage I, and Versant Vantage I GP-GP, LLC ("Versant Vantage I GP-GP") is the general partner of Versant Vantage I GP. Each of Versant Vantage I GP-GP and Versant Vantage I GP may be deemed to share voting, investment and dispositive power over the shares held by Versant Vantage I and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 11

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F17 · kind: Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Vantage I GP-GP to its members.

F16 · ownership.nature: Shares held by Versant Vantage I GP-GP.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 10

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 5,454

F15 · kind: Represents a change in the form of ownership of Versant Vantage I GP-GP by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by Versant Vantage I GP.

F16 · ownership.nature: Shares held by Versant Vantage I GP-GP.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 9

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F14 · kind: Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Vantage I GP to its partners.

F13 · ownership.nature: Shares held by Versant Vantage I GP. Versant Vantage I GP-GP is the general partner of Versant Vantage I GP and may be deemed to share voting, investment and dispositive power over the shares held by Versant Vantage I GP and disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 8

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 5,499

F12 · kind: Represents a change in the form of ownership of Versant Vantage I GP by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by Versant Vantage I.

F13 · ownership.nature: Shares held by Versant Vantage I GP. Versant Vantage I GP-GP is the general partner of Versant Vantage I GP and may be deemed to share voting, investment and dispositive power over the shares held by Versant Vantage I GP and disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 7

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,641,358

F11 · kind: Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Vantage I to its partners.

F2 · ownership.nature: Shares held by Versant Vantage I, L.P. ("Versant Vantage I"). Versant Vantage I GP, L.P. ("Versant Vantage I GP") is the general partner of Versant Vantage I, and Versant Vantage I GP-GP, LLC ("Versant Vantage I GP-GP") is the general partner of Versant Vantage I GP. Each of Versant Vantage I GP-GP and Versant Vantage I GP may be deemed to share voting, investment and dispositive power over the shares held by Versant Vantage I and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 6

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F10 · kind: Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Ventures VI GP-GP to its members.

F9 · ownership.nature: Shares held by Versant Ventures VI GP-GP.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 5

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 17,595

F8 · kind: Represents a change in the form of ownership of Versant Ventures VI GP-GP by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by Versant Ventures VI GP.

F9 · ownership.nature: Shares held by Versant Ventures VI GP-GP.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 4

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F7 · kind: Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Ventures VI GP to its partners.

F6 · ownership.nature: Shares held by Versant Ventures VI GP. Versant Ventures VI GP-GP is the general partner of Versant Ventures VI GP and may be deemed to share voting, investment and dispositive power over the shares held by Versant Ventures VI GP and disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 3

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 20,397

F5 · kind: Represents a change in the form of ownership of Versant Ventures VI GP by virtue of the receipt of shares as a result of the pro-rata in-kind distribution of common stock of the Issuer for no consideration by Versant VI.

F6 · ownership.nature: Shares held by Versant Ventures VI GP. Versant Ventures VI GP-GP is the general partner of Versant Ventures VI GP and may be deemed to share voting, investment and dispositive power over the shares held by Versant Ventures VI GP and disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 2

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,079,469

F3 · kind: Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Versant Venture Capital VI, L.P. ("Versant VI") to its partners.

F4 · ownership.direct: Shares held by Versant VI. Versant Ventures VI GP, L.P. ("Versant Ventures VI GP") is the general partner of Versant VI, and Versant Ventures VI GP-GP, LLC ("Versant Ventures VI GP-GP") is the general partner of Versant Ventures VI GP. Each of Versant Ventures VI GP-GP and Versant Ventures VI GP may be deemed to share voting, investment and dispositive power over the shares held by Versant VI and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-119051 · ownership.xml · nonDerivative · entry 1

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 2,007,948

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $9.50 to $10.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (1) to this Form 4.

F2 · ownership.nature: Shares held by Versant Vantage I, L.P. ("Versant Vantage I"). Versant Vantage I GP, L.P. ("Versant Vantage I GP") is the general partner of Versant Vantage I, and Versant Vantage I GP-GP, LLC ("Versant Vantage I GP-GP") is the general partner of Versant Vantage I GP. Each of Versant Vantage I GP-GP and Versant Vantage I GP may be deemed to share voting, investment and dispositive power over the shares held by Versant Vantage I and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-109112 · ownership.xml · nonDerivative · entry 1

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,099,336

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $6.30 to $6.80, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (1) to this Form 4.

F2 · ownership.direct: Shares held by Versant Venture Capital VI, L.P. ("Versant VI"). Versant Ventures VI GP, L.P. ("Versant Ventures VI GP") is the general partner of Versant VI, and Versant Ventures VI GP-GP, LLC ("Versant Ventures VI GP-GP") is the general partner of Versant Ventures VI GP. Each of Versant VI GP-GP and Versant VI GP may be deemed to share voting, investment and dispositive power over the shares held by Versant VI and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-106387 · ownership.xml · derivative · entry 1

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2032-10-04

F1 · kind: On October 3, 2022, the Reporting Person was granted an option to purchase 30,000 shares of Common Stock, subject to the satisfaction of certain performance criteria. On September 13, 2024, the performance criteria underlying such shares were met.

F2 · derivative.exercise_date: The shares underlying this option shall vest in full on March 13, 2026, subject to the Reporting Person's continued service on such date.

SEC source: 0000950170-24-106532 · ownership.xml · nonDerivative · entry 3

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,231,902

F4 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $6.02 to $6.26, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (4) to this Form 4.

F2 · ownership.direct: Shares held by Versant Venture Capital VI, L.P. ("Versant VI"). Versant Ventures VI GP, L.P. ("Versant Ventures VI GP") is the general partner of Versant VI, and Versant Ventures VI GP-GP, LLC ("Versant Ventures VI GP-GP") is the general partner of Versant Ventures VI GP. Each of Versant VI GP-GP and Versant VI GP may be deemed to share voting, investment and dispositive power over the shares held by Versant VI and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-106532 · ownership.xml · nonDerivative · entry 2

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,241,171

F3 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $6.00 to $6.12, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (3) to this Form 4.

F2 · ownership.direct: Shares held by Versant Venture Capital VI, L.P. ("Versant VI"). Versant Ventures VI GP, L.P. ("Versant Ventures VI GP") is the general partner of Versant VI, and Versant Ventures VI GP-GP, LLC ("Versant Ventures VI GP-GP") is the general partner of Versant Ventures VI GP. Each of Versant VI GP-GP and Versant VI GP may be deemed to share voting, investment and dispositive power over the shares held by Versant VI and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-106532 · ownership.xml · nonDerivative · entry 1

Versant Venture Capital VI, L.P. · CIK 0001687880 · 10% owner

Versant Ventures VI GP, L.P. · CIK 0001777654 · 10% owner

Versant Ventures VI GP-GP, LLC · CIK 0001777652 · 10% owner

Versant Vantage I, L.P. · CIK 0001765253 · 10% owner

Versant Vantage I GP, L.P. · CIK 0001777651 · 10% owner

Versant Vantage I GP-GP, LLC · CIK 0001777653 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,257,218

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $6.00 to $6.01, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the ranges set forth in this footnote (1) to this Form 4.

F2 · ownership.direct: Shares held by Versant Venture Capital VI, L.P. ("Versant VI"). Versant Ventures VI GP, L.P. ("Versant Ventures VI GP") is the general partner of Versant VI, and Versant Ventures VI GP-GP, LLC ("Versant Ventures VI GP-GP") is the general partner of Versant Ventures VI GP. Each of Versant VI GP-GP and Versant VI GP may be deemed to share voting, investment and dispositive power over the shares held by Versant VI and disclaims beneficial ownership of such shares, except to the extent of their respective pecuniary interests therein.

SEC source: 0000950170-24-082416 · ownership.xml · nonDerivative · entry 1

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,944

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.83 to $3.84, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-073064 · ownership.xml · derivative · entry 1

SCHIFF ANDREW N · CIK 0001172252 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,100

Underlying: Common Stock · 22,100 shares

Expires 2034-06-12

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 12, 2025 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0000950170-24-073059 · ownership.xml · derivative · entry 1

Blackwell Kimberly · CIK 0001816465 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,100

Underlying: Common Stock · 22,100 shares

Expires 2034-06-12

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 12, 2025 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0000950170-24-073265 · ownership.xml · derivative · entry 1

Behbahani Ali · CIK 0001613867 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,100

Underlying: Common Stock · 22,100 shares

Expires 2034-06-12

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 12, 2025 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0000950170-24-073062 · ownership.xml · derivative · entry 1

Manning Anthony M. · CIK 0001716468 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,100

Underlying: Common Stock · 22,100 shares

Expires 2034-06-12

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 12, 2025 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0000950170-24-073073 · ownership.xml · derivative · entry 1

Siu Christine · CIK 0001743029 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,100

Underlying: Common Stock · 22,100 shares

Expires 2034-06-12

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 12, 2025 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0000950170-24-073063 · ownership.xml · derivative · entry 1

Skvarka Jan · CIK 0001838042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,100

Underlying: Common Stock · 22,100 shares

Expires 2034-06-12

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 12, 2025 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0000950170-24-069307 · ownership.xml · derivative · entry 1

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2034-06-03

F1 · derivative.exercise_date: 25% of this option shall vest and become exercisable on May 28, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-069310 · ownership.xml · nonDerivative · entry 1

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,554

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.0111 to $4.04, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0000950170-24-069308 · ownership.xml · derivative · entry 1

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2034-06-03

F1 · derivative.exercise_date: 25% of this option shall vest and become exercisable on May 28, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-069309 · ownership.xml · derivative · entry 1

Nickson Philip · CIK 0001911369 · Chief Business & Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Underlying: Common Stock · 40,000 shares

Expires 2034-06-03

F1 · derivative.exercise_date: 25% of this option shall vest and become exercisable on May 28, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-24-000765 · doc4.xml · derivative · entry 2

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,900

Underlying: Common Stock · 35,900 shares

Expires 2034-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-24-000765 · doc4.xml · derivative · entry 1

Dunn Edmund · CIK 0001989401 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2034-01-01

F1 · derivative.exercise_date: 25% of this option shall vest and become exercisable on October 2, 2024, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-24-000766 · doc4.xml · derivative · entry 1

Jones Jullian G · CIK 0001895356 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,000

Underlying: Common Stock · 79,000 shares

Expires 2034-01-01

F1 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-24-000764 · doc4.xml · derivative · entry 2

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,000

Underlying: Common Stock · 121,000 shares

Expires 2034-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-24-000767 · doc4.xml · derivative · entry 1

Warmuth Markus · CIK 0001855643 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 346,000

Underlying: Common Stock · 346,000 shares

Expires 2034-01-01

F1 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001209191-24-000768 · doc4.xml · derivative · entry 2

Wallace Owen B. · CIK 0001778843 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,000

Underlying: Common Stock · 119,000 shares

Expires 2034-01-01

F2 · derivative.exercise_date: 25% of this option shall vest and become exercisable on January 1, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.