GLUE

SEC source: 0001193125-26-415540 · ownership.xml · nonDerivative · entry 1

Bowen Matthew · CIK 0002115025 · Principal Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,891

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

SEC source: 0001193125-26-307791 · ownership.xml · nonDerivative · entry 1

Warmuth Markus · CIK 0001855643 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 585,038

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.18 to $23.23, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-306110 · ownership.xml · derivative · entry 3

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 26,947

Underlying: Common Stock · 4,351 shares

Expires 2034-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

F3 · derivative.exercise_date: 25% of the shares underlying this option vested on May 28, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-306110 · ownership.xml · nonDerivative · entry 2

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,371

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.83 to $23.71, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-306110 · ownership.xml · nonDerivative · entry 1

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,722

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

SEC source: 0001193125-26-297558 · ownership.xml · derivative · entry 4

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 197,290

Underlying: Common Stock · 6,000 shares

Expires 2031-04-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F3 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-297558 · ownership.xml · nonDerivative · entry 3

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,845

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

SEC source: 0001193125-26-297558 · ownership.xml · nonDerivative · entry 2

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,245

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.97 to $23.65, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-297558 · ownership.xml · nonDerivative · entry 1

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 73,845

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

SEC source: 0001193125-26-296490 · ownership.xml · nonDerivative · entry 3

Behbahani Ali · CIK 0001613867 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 4

Disclosed balance after: 0

F5 · kind: NEA Partners 17 made a distribution of 15,000 shares of Common Stock of the Issuer for no consideration on July 1, 2026.

F4 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, the sole general partner of NEA Partners 17, the direct beneficial owner of the shares. The Reporting Person disclaims beneficial ownership, within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Partners 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-296490 · ownership.xml · nonDerivative · entry 2

Behbahani Ali · CIK 0001613867 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 4

Disclosed balance after: 15,000

F3 · kind: NEA Partners 17 received 15,000 shares of Common Stock of the Issuer in the distribution made by NEA 17 on July 1, 2026.

F4 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, the sole general partner of NEA Partners 17, the direct beneficial owner of the shares. The Reporting Person disclaims beneficial ownership, within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Partners 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-296490 · ownership.xml · nonDerivative · entry 1

Behbahani Ali · CIK 0001613867 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 6,692,298

F1 · kind: New Enterprise Associates 17, L.P. ("NEA 17") made a pro rata distribution of 1,000,000 shares of Common Stock of the Issuer to its general partner and limited partners for no consideration on July 1, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC ("NEA 17 GP"), which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of NEA 17, the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership, within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-292767 · ownership.xml · derivative · entry 3

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 81,093

Underlying: Common Stock · 5,407 shares

Expires 2032-02-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F3 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-292767 · ownership.xml · nonDerivative · entry 2

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,612

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

SEC source: 0001193125-26-292767 · ownership.xml · nonDerivative · entry 1

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,019

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F2 · balance_after: Includes 620 shares acquired under the Issuer's 2021 Employee Stock Purchase Program on June 30, 2026.

SEC source: 0001193125-26-290486 · ownership.xml · derivative · entry 3

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 6,000 shares

Expires 2032-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F2 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-290486 · ownership.xml · nonDerivative · entry 2

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 59,992

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

SEC source: 0001193125-26-290486 · ownership.xml · nonDerivative · entry 1

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 65,992

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

SEC source: 0001193125-26-290484 · ownership.xml · derivative · entry 3

Manning Anthony M. · CIK 0001716468 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,100

Underlying: Common Stock · 10,000 shares

Expires 2034-06-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-290484 · ownership.xml · nonDerivative · entry 2

Manning Anthony M. · CIK 0001716468 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

SEC source: 0001193125-26-290484 · ownership.xml · nonDerivative · entry 1

Manning Anthony M. · CIK 0001716468 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001193125-26-282740 · ownership.xml · derivative · entry 6

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,000

Underlying: Common Stock · 30,000 shares

Expires 2032-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F4 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-282740 · ownership.xml · nonDerivative · entry 4

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 59,992

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $21.30 to $21.59, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-282740 · ownership.xml · nonDerivative · entry 3

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 89,992

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

SEC source: 0001193125-26-282735 · ownership.xml · derivative · entry 3

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,298

Underlying: Common Stock · 2,175 shares

Expires 2034-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

F2 · derivative.exercise_date: 25% of this option vested on May 28, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-282735 · ownership.xml · nonDerivative · entry 2

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,371

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

SEC source: 0001193125-26-282735 · ownership.xml · nonDerivative · entry 1

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 64,546

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

SEC source: 0001193125-26-282740 · ownership.xml · derivative · entry 5

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 6,000 shares

Expires 2032-10-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F4 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-282740 · ownership.xml · nonDerivative · entry 2

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 59,992

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.95 to $20.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-282740 · ownership.xml · nonDerivative · entry 1

Janku Filip · CIK 0001862930 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,837

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 4, 2026.

SEC source: 0001193125-26-282736 · ownership.xml · derivative · entry 3

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 203,290

Underlying: Common Stock · 3,000 shares

Expires 2031-04-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F2 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

SEC source: 0001193125-26-282736 · ownership.xml · nonDerivative · entry 2

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,845

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

SEC source: 0001193125-26-282736 · ownership.xml · nonDerivative · entry 1

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,845

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

SEC source: 0001193125-26-275806 · ownership.xml · derivative · entry 3

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 33,473

Underlying: Common Stock · 2,176 shares

Expires 2034-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

F2 · derivative.exercise_date: 25% of this option vested on May 28, 2025, with the remainder vesting in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-275806 · ownership.xml · nonDerivative · entry 2

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,371

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

SEC source: 0001193125-26-275806 · ownership.xml · nonDerivative · entry 1

Champoux Jennifer · CIK 0002025233 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 64,547

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 19, 2026.

SEC source: 0001193125-26-275805 · ownership.xml · derivative · entry 3

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 206,290

Underlying: Common Stock · 3,000 shares

Expires 2031-04-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F2 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001193125-26-275805 · ownership.xml · nonDerivative · entry 2

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,845

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

SEC source: 0001193125-26-275805 · ownership.xml · nonDerivative · entry 1

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 70,845

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

SEC source: 0001193125-26-269365 · ownership.xml · derivative · entry 1

SCHIFF ANDREW N · CIK 0001172252 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-269348 · ownership.xml · derivative · entry 1

Hughes Eric A · CIK 0001938678 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-269349 · ownership.xml · derivative · entry 1

Blackwell Kimberly · CIK 0001816465 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-269885 · ownership.xml · derivative · entry 1

Behbahani Ali · CIK 0001613867 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-269354 · ownership.xml · derivative · entry 1

Manning Anthony M. · CIK 0001716468 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-269368 · ownership.xml · derivative · entry 1

Siu Christine · CIK 0001743029 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-269378 · ownership.xml · derivative · entry 1

Skvarka Jan · CIK 0001838042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,800

Underlying: Common Stock · 25,800 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable in full upon the earlier to occur of (i) June 11, 2027 or (ii) the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service at such time.

SEC source: 0001193125-26-253472 · ownership.xml · nonDerivative · entry 2

Warmuth Markus · CIK 0001855643 · Director · President & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 594,538

F1 · kind: These transactions were effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on May 14, 2025.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.69 to $19.77, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-253472 · ownership.xml · nonDerivative · entry 1

Warmuth Markus · CIK 0001855643 · Director · President & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 595,006

F1 · kind: These transactions were effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted on May 14, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $18.69 to $19.68, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

SEC source: 0001193125-26-251395 · ownership.xml · derivative · entry 3

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 209,290

Underlying: Common Stock · 6,000 shares

Expires 2031-04-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F3 · derivative.exercise_date: This option is fully vested and exercisable.

SEC source: 0001193125-26-251395 · ownership.xml · nonDerivative · entry 2

Townson Sharon · CIK 0001855689 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,845

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 27, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $19.74 to $20.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.