APRE

SEC source: 0001104659-23-095020 · tm2324788-7_4seq1.xml · derivative · entry 2

Grissinger Michael · CIK 0001757601 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 2,000 shares

Expires 2033-08-23

F2 · derivative.exercise_date: The option vests in full on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095020 · tm2324788-7_4seq1.xml · nonDerivative · entry 1

Grissinger Michael · CIK 0001757601 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 799

F1 · shares: These shares represent restricted stock units which were granted on August 23, 2023, and which will vest and be settled in common stock on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095019 · tm2324788-6_4seq1.xml · derivative · entry 2

HENNEMAN JOHN B III · CIK 0001187572 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 2,000 shares

Expires 2033-08-23

F2 · derivative.exercise_date: The option vests in full on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095019 · tm2324788-6_4seq1.xml · nonDerivative · entry 1

HENNEMAN JOHN B III · CIK 0001187572 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,279

F1 · shares: These shares represent restricted stock units which were granted on August 23, 2023, and which will vest and be settled in common stock on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095014 · tm2324788-3_4seq1.xml · derivative · entry 1

BIZZARI JEAN-PIERRE · CIK 0001630914 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2033-08-23

F1 · derivative.exercise_date: These options shall vest in full on the two year anniversary of the grant date, subject to the reporting person's continued service on the Issuer's board of Directors through and including the applicable vesting date.

SEC source: 0001104659-23-095018 · tm2324788-5_4seq1.xml · derivative · entry 2

Peters Richard · CIK 0001697628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 2,000 shares

Expires 2033-08-23

F2 · derivative.exercise_date: The option vests in full on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095018 · tm2324788-5_4seq1.xml · nonDerivative · entry 1

Peters Richard · CIK 0001697628 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,029

F1 · shares: These shares represent restricted stock units which were granted on August 23, 2023, and which will vest and be settled in common stock on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095016 · tm2324788-1_4seq1.xml · derivative · entry 2

Seizinger Bernd R. · CIK 0001789042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000

Underlying: Common Stock · 2,000 shares

Expires 2033-08-23

F2 · derivative.exercise_date: The option vests in full on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-095016 · tm2324788-1_4seq1.xml · nonDerivative · entry 1

Seizinger Bernd R. · CIK 0001789042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,825

F1 · shares: These shares represent restricted stock units which were granted on August 23, 2023, and which will vest and be settled in common stock on August 23, 2024, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-23-069421 · tm2318158-1_4seq1.xml · nonDerivative · entry 2

Seizinger Bernd R. · CIK 0001789042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,325

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.65 to $3.70, inclusive. The reporting person undertakes to provide to Aprea Therapeutics, Inc., any security holder of Aprea Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth.

F3 · balance_after: Reflects a one-for-20 reverse split, effective as of 5:00 p.m. Eastern Time on February 10, 2023.

SEC source: 0001104659-23-069421 · tm2318158-1_4seq1.xml · nonDerivative · entry 1

Seizinger Bernd R. · CIK 0001789042 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,296

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.4984 to $3.75, inclusive. The reporting person undertakes to provide to Aprea Therapeutics, Inc., any security holder of Aprea Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth.

SEC source: 0001104659-23-057260 · tm2314936-2_4seq1.xml · derivative · entry 1

Gruia Gabriela · CIK 0001860326 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2033-05-05

F1 · derivative.exercise_date: These options shall vest in full on May 5, 2024, subject to the reporting person's continued service through and including the applicable vesting date.

SEC source: 0001104659-23-031882 · tm239268d1_4.xml · derivative · entry 4

Gilad Oren · CIK 0001929300 · Director · President, CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2033-03-09

F3 · derivative.exercise_date: Twenty-five percent of these options vest on March 9, 2024, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-23-031882 · tm239268d1_4.xml · nonDerivative · entry 2

Gilad Oren · CIK 0001929300 · Director · President, CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 322,770

F1 · shares: These shares represent restricted stock units ("RSUs") and shall vest and be settled in the Issuer's common stock ("Common Stock") in three (3) equal annual installments beginning on March 9, 2024 until vested in full, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

F4 · balance_after: Reflects a one-for-20 reverse split, effective as of 5:00 p.m. Eastern Time on February 10, 2023.

SEC source: 0001104659-23-026159 · tm238004-1_4seq1.xml · nonDerivative · entry 1

Hamill John P. · CIK 0001716213 · SrVP/CFO/Prin Fin & Acct Ofcr

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,493

F1 · balance_after: Effective February 13, 2023, the Issuer completed a 1-for-20 reverse stock split (the "Reverse Stock Split") of its outstanding Common Stock. The number of securities reported on this Form 4 has been adjusted to reflect the Reverse Stock Split.

SEC source: 0001104659-23-008064 · tm234680-2_4seq1.xml · derivative · entry 2

Hamill John P. · CIK 0001716213 · SrVP/CFO/Prin. Fin&Acctg. Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 539,758

Underlying: Common Stock · 539,758 shares

Expires 2033-01-30

F2 · derivative.exercise_date: Twenty-five percent of these options vest on January 30, 2024, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-23-008064 · tm234680-2_4seq1.xml · nonDerivative · entry 1

Hamill John P. · CIK 0001716213 · SrVP/CFO/Prin. Fin&Acctg. Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 269,879

F1 · shares: These shares represent restricted stock units which were granted on January 30, 2023, and which will vest and be settled in common stock in three equal, annual installments beginning on January 30, 2024, January 30, 2025, and January 30, 2026, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-23-031882 · tm239268d1_4.xml · derivative · entry 3

Gilad Oren · CIK 0001929300 · Director · President, CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,045,100 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of Common Stock any time at the option of the holder thereof, subject to certain limitations. On August 23, 2022, the Reporting Person converted 604,510 shares of Series A Non-Voting Convertible Preferred Stock into 6,045,100 shares of Common Stock.

F2 · derivative.exercise_date: Each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of Common Stock any time at the option of the holder thereof, subject to certain limitations. On August 23, 2022, the Reporting Person converted 604,510 shares of Series A Non-Voting Convertible Preferred Stock into 6,045,100 shares of Common Stock.

F2 · derivative.expiration_date: Each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of Common Stock any time at the option of the holder thereof, subject to certain limitations. On August 23, 2022, the Reporting Person converted 604,510 shares of Series A Non-Voting Convertible Preferred Stock into 6,045,100 shares of Common Stock.

SEC source: 0001104659-23-031882 · tm239268d1_4.xml · nonDerivative · entry 1

Gilad Oren · CIK 0001929300 · Director · President, CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,375,414

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · shares: Each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of Common Stock any time at the option of the holder thereof, subject to certain limitations. On August 23, 2022, the Reporting Person converted 604,510 shares of Series A Non-Voting Convertible Preferred Stock into 6,045,100 shares of Common Stock.

SEC source: 0001104659-23-095021 · tm2324788-8_4seq1.xml · derivative · entry 5

Pamukcu Rifat · CIK 0001929298 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By ZNZ Holdings LLC

Disclosed balance after: 0

Underlying: Common Stock · 271,870 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F1 · derivative.expiration_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F4 · ownership.nature: The Reporting Person serves as Manager Partner of ZNZ Holdings L.L.C.

SEC source: 0001104659-23-095021 · tm2324788-8_4seq1.xml · derivative · entry 4

Pamukcu Rifat · CIK 0001929298 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 49,280 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F1 · derivative.expiration_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

SEC source: 0001104659-23-095021 · tm2324788-8_4seq1.xml · nonDerivative · entry 3

Pamukcu Rifat · CIK 0001929298 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By ZNZ Holdings LLC

Disclosed balance after: 14,108

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F3 · balance_after: Reflects a one-for-20 reverse split, effective as of 5:00 p.m. Eastern Time on February 10, 2023

F4 · ownership.nature: The Reporting Person serves as Manager Partner of ZNZ Holdings L.L.C.

SEC source: 0001104659-23-095021 · tm2324788-8_4seq1.xml · nonDerivative · entry 1

Pamukcu Rifat · CIK 0001929298 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 57,142

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

SEC source: 0001104659-23-095017 · tm2324788-4_4seq1.xml · derivative · entry 5

Duey Marc · CIK 0001925150 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 0

Underlying: Common Stock · 11,610 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F4 · derivative.expiration_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F3 · ownership.nature: The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose.

SEC source: 0001104659-23-095017 · tm2324788-4_4seq1.xml · derivative · entry 4

Duey Marc · CIK 0001925150 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,009,690 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

F4 · derivative.expiration_date: Following stockholder approval at the Issuer's annual stockholder's meeting, each share of Series A Non-Voting Convertible Preferred Stock is convertible into 10 shares of the Issuer's common stock ("Common Stock") at any time at the option of the holder thereof, subject to certain limitations, including that a holder of Series A Non-Voting Convertible Preferred Stock is prohibited from converting shares of Series A Non-Voting Convertible Preferred Stock into shares of Common Stock if, as a result of such conversion, such holder, together with its affiliates, would beneficially own more than a specified percentage (to be established by the holder between 4.9% and 19.9%) of the total number of shares of Common Stock issued and outstanding immediately after giving effect to such conversion. The Series A Non-Voting Convertible Preferred Stock has no expiration date.

SEC source: 0001104659-23-095017 · tm2324788-4_4seq1.xml · nonDerivative · entry 3

Duey Marc · CIK 0001925150 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 602

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · balance_after: Reflects a one-for-20 reverse split, effective as of 5:00 p.m. Eastern Time on February 10, 2023

F3 · ownership.nature: The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose.

SEC source: 0001104659-23-095017 · tm2324788-4_4seq1.xml · nonDerivative · entry 1

Duey Marc · CIK 0001925150 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,167,589

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001104659-22-084768 · tm2222147-7_4seq1.xml · derivative · entry 3

Pamukcu Rifat · CIK 0001929298 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,575

Underlying: Common Stock · 29,575 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084768 · tm2222147-7_4seq1.xml · nonDerivative · entry 1

Pamukcu Rifat · CIK 0001929298 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,862

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084763 · tm2222147-3_4seq1.xml · derivative · entry 2

Gilad Oren · CIK 0001929300 · President, CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 148,700

Underlying: Common Stock · 148,700 shares

Expires 2032-07-28

F2 · derivative.exercise_date: Twenty-five percent of these options vest on July 28, 2023, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084763 · tm2222147-3_4seq1.xml · nonDerivative · entry 1

Gilad Oren · CIK 0001929300 · President, CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 330,314

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock as follows: (i) 33,766 shares on July 28, 2023, (ii) 33,767 shares on July 28, 2024 and (iii) 33,767 shares on July 28, 2025, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084762 · tm2222147-2_4seq1.xml · derivative · entry 3

Duey Marc · CIK 0001925150 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,575

Underlying: Common Stock · 29,575 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084762 · tm2222147-2_4seq1.xml · nonDerivative · entry 1

Duey Marc · CIK 0001925150 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 157,899

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084764 · tm2222147-4_4seq1.xml · derivative · entry 2

Grissinger Michael · CIK 0001757601 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,575

Underlying: Common Stock · 29,575 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084764 · tm2222147-4_4seq1.xml · nonDerivative · entry 1

Grissinger Michael · CIK 0001757601 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,995

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084765 · tm2222147-5_4seq1.xml · derivative · entry 2

HENNEMAN JOHN B III · CIK 0001187572 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,575

Underlying: Common Stock · 29,575 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084765 · tm2222147-5_4seq1.xml · nonDerivative · entry 1

HENNEMAN JOHN B III · CIK 0001187572 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,605

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084772 · tm2222147-9_4seq1.xml · derivative · entry 9

SCHADE CHRISTIAN S · CIK 0001214496 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,600

Underlying: Common Stock · 47,600 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084772 · tm2222147-9_4seq1.xml · nonDerivative · entry 1

SCHADE CHRISTIAN S · CIK 0001214496 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 259,246

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084760 · tm2222147-1_4seq1.xml · derivative · entry 2

Coiante Scott M · CIK 0001608536 · SVP, Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 89,200

Underlying: Common Stock · 89,200 shares

Expires 2032-07-28

F2 · derivative.exercise_date: Twenty-five percent of these options vest on July 28, 2023, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084760 · tm2222147-1_4seq1.xml · nonDerivative · entry 1

Coiante Scott M · CIK 0001608536 · SVP, Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,065

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock as follows: (i) 20,266 shares on July 28, 2023, (ii) 20,267 shares on July 28, 2024 and (iii) 20,267 shares on July 28, 2025, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084770 · tm2222147-8_4seq1.xml · derivative · entry 2

Peters Richard · CIK 0001697628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,575

Underlying: Common Stock · 29,575 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084770 · tm2222147-8_4seq1.xml · nonDerivative · entry 1

Peters Richard · CIK 0001697628 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,605

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084775 · tm2222147-10_4seq1.xml · derivative · entry 2

Seizinger Bernd R. · CIK 0001789042 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,575

Underlying: Common Stock · 29,575 shares

Expires 2032-07-28

F2 · derivative.exercise_date: The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084775 · tm2222147-10_4seq1.xml · nonDerivative · entry 1

Seizinger Bernd R. · CIK 0001789042 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 324,575

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084767 · tm2222147-6_4seq1.xml · derivative · entry 2

Korbel Gregory Alan · CIK 0001789032 · SVP, Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,700

Underlying: Common Stock · 35,700 shares

Expires 2032-07-28

F2 · derivative.exercise_date: Twenty-five percent of these options vest on July 28, 2023, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-22-084767 · tm2222147-6_4seq1.xml · nonDerivative · entry 1

Korbel Gregory Alan · CIK 0001789032 · SVP, Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,762

F1 · shares: These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock as follows: (i) 8,100 shares on July 28, 2023, (ii) 8,100 shares on July 28, 2024 and (iii) 8,100 shares on July 28, 2025, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions.

SEC source: 0001104659-22-069015 · tm2217848-4_4seq1.xml · nonDerivative · entry 1

SCHADE CHRISTIAN S · CIK 0001214496 · Director · Chairman & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 226,846

F1 · shares: Represents shares withheld to satisfy tax withholding obligations in connection with the vesting of 180,934 restricted stock units.

SEC source: 0001104659-22-069009 · tm2217848-3_4seq1.xml · nonDerivative · entry 1

Coiante Scott M · CIK 0001608536 · Director · SVP, Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 84,265

F1 · shares: Represents shares withheld to satisfy tax withholding obligations in connection with the vesting of 86,067 restricted stock units.

SEC source: 0001104659-22-069001 · tm2217848-2_4seq1.xml · nonDerivative · entry 1

Korbel Gregory Alan · CIK 0001789032 · Director · SVP, Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,462

F1 · shares: Represents shares withheld to satisfy tax withholding obligations in connection with the vesting of 24,334 restricted stock units