ANTX

SEC source: 0000899243-22-034497 · doc4.xml · nonDerivative · entry 2

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,907

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034497 · doc4.xml · nonDerivative · entry 1

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,590

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034294 · doc4.xml · nonDerivative · entry 4

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,907

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034294 · doc4.xml · nonDerivative · entry 3

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,585

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034294 · doc4.xml · nonDerivative · entry 2

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,119

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034294 · doc4.xml · nonDerivative · entry 1

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,391

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034092 · doc4.xml · nonDerivative · entry 4

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,907

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034092 · doc4.xml · nonDerivative · entry 3

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,257

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034092 · doc4.xml · nonDerivative · entry 2

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,858

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034092 · doc4.xml · nonDerivative · entry 1

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,889

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0000899243-22-034442 · doc4.xml · derivative · entry 1

Eizen Joshua M · CIK 0001949621 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,000

Underlying: Common Stock · 92,000 shares

Expires 2032-10-13

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 25% of the shares shall vest on the anniversary of September 29, 2022, and the remainder of the shares shall vest ratably monthly over the subsequent 36 months.

SEC source: 0001104659-22-086686 · tm2222743-1_4seq1.xml · nonDerivative · entry 2

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 3,773,517

F3 · balance_after: These securities include 3,357,905 shares held directly by the Fund and 415,612 shares held by the Nexus Fund II.

F4 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0001104659-22-086686 · tm2222743-1_4seq1.xml · nonDerivative · entry 1

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,773,417

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.34 to $7.68; the price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which these transactions, and all other transactions reported in this Form 4, were effected upon request to the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

F1 · balance_after: These securities include 3,357,805 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F1 · ownership.nature: These securities include 3,357,805 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F4 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0001104659-22-083728 · tm2222103-1_4seq1.xml · nonDerivative · entry 2

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,771,608

F4 · price: This transaction was executed in multiple trades at prices ranging from $7.67 to $8.00; the price reported above reflects the weighted average purchase price.

F3 · balance_after: These securities include 3,355,996 shares held directly by the Fund and 415,612 shares held by the Nexus Fund II.

F3 · ownership.nature: These securities include 3,355,996 shares held directly by the Fund and 415,612 shares held by the Nexus Fund II.

F5 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0001104659-22-083728 · tm2222103-1_4seq1.xml · nonDerivative · entry 1

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,763,327

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.43 to $7.92; the price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which these transactions, and all other transactions reported in this Form 4, were effected upon request to the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

F1 · balance_after: These securities include 3,347,715 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F1 · ownership.nature: These securities include 3,347,715 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F5 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0001104659-22-073920 · tm2219316-1_4seq1.xml · nonDerivative · entry 1

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,748,389

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.99 to $8.00; the price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which these transactions, and all other transactions reported in this Form 4, were effected upon request to the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

F1 · balance_after: These securities include 3,332,777 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F1 · ownership.nature: These securities include 3,332,777 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F3 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0001104659-22-071465 · tm2218531-1_4seq1.xml · nonDerivative · entry 2

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,748,087

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.725 to $8.00; the price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide full information regarding the number of shares and prices at which these transactions, and all other transactions reported in this Form 4, were effected upon request to the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

F3 · balance_after: These securities include 3,332,475 shares held directly by the Fund and 415,612 shares held by Nexus Fund II.

F3 · ownership.nature: These securities include 3,332,475 shares held directly by the Fund and 415,612 shares held by Nexus Fund II.

F4 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0001104659-22-071465 · tm2218531-1_4seq1.xml · nonDerivative · entry 1

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · 10% owner

RA Capital Nexus Fund II, L.P. · CIK 0001825376 · 10% owner

Kolchinsky Peter · CIK 0001384859 · 10% owner

Shah Rajeev M. · CIK 0001619841 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 3,686,663

F1 · balance_after: These securities include 3,271,051 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F1 · ownership.nature: These securities include 3,271,051 shares held directly by RA Capital Healthcare Fund, L.P. (the "Fund") and 415,612 shares held by RA Capital Nexus Fund II, L.P. (the "Nexus Fund II").

F4 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for the Fund and the Nexus Fund II. The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. The Adviser, the Adviser GP, Dr. Kolchinsky and Mr. Shah disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein.

SEC source: 0000899243-22-024050 · doc4.xml · nonDerivative · entry 2

Adjuvant Global Health Technology Fund, L.P. · CIK 0001783165 · 10% owner

Adjuvant Global Health Technology Fund DE, L.P. · CIK 0001799812 · 10% owner

Adjuvant Capital GP, L.P. · CIK 0001935100 · 10% owner

Adjuvant Capital Management, LLC · CIK 0001935084 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Adjuvant Global Health Technology Fund DE, L.P.

Disclosed balance after: 413,156

F1 · kind: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F1 · price: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F3 · ownership.nature: Shares held directly by AGHT Fund DE. The sole general partner of AGHT Fund DE is AC GP and the sole general partner of AC GP is AC MGMT. Kabeer Aziz, a member of the Issuer's board of directors, is Secretary of AC MGMT, and may be deemed to share voting and dispositive power over the securities held by such entities. Each such person and entity disclaims beneficial ownership of the securities, except to the extent of such person's or entity's pecuniary interest in such securities.

SEC source: 0000899243-22-024050 · doc4.xml · nonDerivative · entry 1

Adjuvant Global Health Technology Fund, L.P. · CIK 0001783165 · 10% owner

Adjuvant Global Health Technology Fund DE, L.P. · CIK 0001799812 · 10% owner

Adjuvant Capital GP, L.P. · CIK 0001935100 · 10% owner

Adjuvant Capital Management, LLC · CIK 0001935084 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,184,224

F1 · kind: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F1 · price: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F2 · ownership.direct: Shares held directly by AGHT Fund. The sole general partner of AGHT Fund is Adjuvant Capital GP, L.P. ("AC GP") and the sole general partner of AC GP is Adjuvant Capital Management, L.L.C. ("AC MGMT"). Kabeer Aziz, a member of the Issuer's board of directors, is Secretary of AC MGMT, and may be deemed to share voting and dispositive power over the securities held by such entities. Each such person and entity disclaims beneficial ownership of the securities, except to the extent of such person's or entity's pecuniary interest in such securities.

SEC source: 0000899243-22-024054 · doc4.xml · nonDerivative · entry 2

Aziz Kabeer · CIK 0001914847 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Adjuvant Global Health Technology Fund DE, L.P.

Disclosed balance after: 413,156

F1 · kind: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F1 · price: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F3 · ownership.nature: Shares held directly by AGHT Fund DE. The sole general partner of AGHT Fund DE is AC GP and the sole general partner of AC GP is AC MGMT. The Reporting Person is a member of the Issuer's board of directors and is Secretary of AC MGMT, and may be deemed to share voting and dispositive power over the securities held by such entities. Each such person and entity disclaims beneficial ownership of the securities, except to the extent of such person's or entity's pecuniary interest in such securities.

SEC source: 0000899243-22-024054 · doc4.xml · nonDerivative · entry 1

Aziz Kabeer · CIK 0001914847 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Adjuvant Global Health Technology Fund, L.P.

Disclosed balance after: 2,184,224

F1 · kind: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F1 · price: On June 6, 2022, Adjuvant Global Health Technology Fund, L.P. ("AGHT Fund") transferred to Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE") 26,511 shares of the Issuer's common stock, with a value of $15.00 per share, which is the per share cost of the shares acquired by AGHT Fund.

F2 · ownership.nature: Shares held directly by AGHT Fund. The sole general partner of AGHT Fund is Adjuvant Capital GP, L.P. ("AC GP") and the sole general partner of AC GP is Adjuvant Capital Management, L.L.C. ("AC MGMT"). The Reporting Person is a member of the Issuer's board of directors and is Secretary of AC MGMT, and may be deemed to share voting and dispositive power over the securities held by such entities. Each such person and entity disclaims beneficial ownership of the securities, except to the extent of such person's or entity's pecuniary interest in such securities.

SEC source: 0000899243-22-018296 · doc4.xml · derivative · entry 1

Chanda Sanjay · CIK 0001571820 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,000

Underlying: Common Stock · 66,000 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/48 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018293 · doc4.xml · derivative · entry 1

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,724

Underlying: Common Stock · 20,724 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/36 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018292 · doc4.xml · derivative · entry 1

Eckburg Paul · CIK 0001914512 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,000

Underlying: Common Stock · 66,000 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/48 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018289 · doc4.xml · derivative · entry 1

Wong Stephanie · CIK 0001555744 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018290 · doc4.xml · derivative · entry 1

Martin Patricia A. · CIK 0001916764 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018287 · doc4.xml · derivative · entry 1

Nazak Michael Adrian · CIK 0001799731 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,300

Underlying: Common Stock · 14,300 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/48 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018286 · doc4.xml · derivative · entry 1

FitzPatrick Margaret M · CIK 0001873879 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from May 5, 2022.

SEC source: 0000899243-22-018282 · doc4.xml · derivative · entry 1

Aziz Kabeer · CIK 0001914847 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,724

Underlying: Common Stock · 20,724 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/36 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018281 · doc4.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018278 · doc4.xml · derivative · entry 1

Krause Kevin Michael · CIK 0001916925 · Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,000

Underlying: Common Stock · 66,000 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/48 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018276 · doc4.xml · derivative · entry 1

Day Lucy · CIK 0001914510 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,000

Underlying: Common Stock · 66,000 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/48 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018273 · doc4.xml · derivative · entry 1

Zakrzewski Joseph S · CIK 0001331852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018272 · doc4.xml · derivative · entry 1

Marks Gilbert Lynn · CIK 0001916940 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-018271 · doc4.xml · derivative · entry 1

Easom Eric · CIK 0001914503 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 225,000

Underlying: Common Stock · 225,000 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/48 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

SEC source: 0000899243-22-017371 · doc4.xml · derivative · entry 1

FitzPatrick Margaret M · CIK 0001873879 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,463

Underlying: Common Stock · 11,463 shares

Expires 2032-05-04

F1 · derivative.exercise_date: The shares subject to the Option shall vest on a monthly basis over a three-year period as measured from May 5, 2022.

SEC source: 0000899243-22-012991 · doc4.xml · derivative · entry 10

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 71,839 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.exercise_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.expiration_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F3 · ownership.nature: Shares held directly by MGC Venture Partners QP 2018 LP ("MGC 2018 QP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · derivative · entry 9

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 61,491 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.exercise_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.expiration_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F2 · ownership.nature: Shares held directly by MGC Venture Partners 2018, LP. ("MGC 2018 LP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · derivative · entry 8

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 333,135 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.exercise_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.expiration_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F3 · ownership.nature: Shares held directly by MGC Venture Partners QP 2018 LP ("MGC 2018 QP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · derivative · entry 7

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 0

Underlying: Common Stock · 285,156 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.exercise_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.expiration_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F2 · ownership.nature: Shares held directly by MGC Venture Partners 2018, LP. ("MGC 2018 LP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · nonDerivative · entry 6

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 487,592

F3 · ownership.nature: Shares held directly by MGC Venture Partners QP 2018 LP ("MGC 2018 QP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · nonDerivative · entry 5

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 417,363

F2 · ownership.nature: Shares held directly by MGC Venture Partners 2018, LP. ("MGC 2018 LP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · nonDerivative · entry 4

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 404,974

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F3 · ownership.nature: Shares held directly by MGC Venture Partners QP 2018 LP ("MGC 2018 QP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · nonDerivative · entry 3

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 346,647

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F2 · ownership.nature: Shares held directly by MGC Venture Partners 2018, LP. ("MGC 2018 LP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · nonDerivative · entry 2

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 333,135

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F3 · ownership.nature: Shares held directly by MGC Venture Partners QP 2018 LP ("MGC 2018 QP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012991 · doc4.xml · nonDerivative · entry 1

Readnour Robin Shane · CIK 0001914883 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnotes

Disclosed balance after: 285,156

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F2 · ownership.nature: Shares held directly by MGC Venture Partners 2018, LP. ("MGC 2018 LP").

F4 · ownership.nature: MGC Venture Partners 2018 GP, LLC ("MGC 2018 GP") is the general partner of MGC 2018 LP and MGC 2018 QP. MGC 2018 GP has shared voting and shared dispositive power over the shares held by MGC 2018 LP and MGC 2018 QP. The Reporting Person is a member of the Issuer's board of directors and is a member of MGC 2018 QP and MGC 2018 LP and a managing partner of MGC 2018 GP and has shared voting power and shared dispositive power over the shares of common stock held by MGC 2018 LP and MGC 2018 QP. The Reporting Person disclaims beneficial ownership of the securities, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0000899243-22-012992 · doc4.xml · derivative · entry 2

Zakrzewski Joseph S · CIK 0001331852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 98,199 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.exercise_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.expiration_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

SEC source: 0000899243-22-012992 · doc4.xml · nonDerivative · entry 1

Zakrzewski Joseph S · CIK 0001331852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,199

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

SEC source: 0000899243-22-012990 · doc4.xml · derivative · entry 9

Adjuvant Global Health Technology Fund, L.P. · CIK 0001783165 · 10% owner

Adjuvant Global Health Technology Fund DE, L.P. · CIK 0001799812 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Adjuvant Global Health Technology Fund DE, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 74,230 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.exercise_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F1 · derivative.expiration_date: Each share of Preferred Stock automatically converts on a one-for-one basis into Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO"), for no additional consideration. The shares of Preferred Stock have no expiration date.

F3 · ownership.nature: Shares held directly by Adjuvant Global Health Technology Fund DE, L.P. ("AGHT Fund DE"). The sole general partner of AGHT Fund DE is AC GP and the sole general partner of AC GP is AC MGMT. Kabeer Aziz, a member of the Issuer's board of directors, is Secretary of AC MGMT, and may be deemed to share voting and dispositive power over the securities held by such entities. Each such person and entity disclaims beneficial ownership of the securities, except to the extent of such person's or entity's pecuniary interest in such securities.