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person · Reporting owner

Spigelman Melvin K

Disclosed activity across 3 companies

Tapewire entity
56571
SEC CIK
0001339901

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
AN2 Therapeutics, Inc.ANTX · Entity 1085DirectorMarch 19, 2026March 23, 2026
MEDICINES CO /DEMDCO · Entity 152552DirectorMay 25, 2018May 29, 2018
SYNERGY PHARMACEUTICALS, INC.SGYP · Entity 164269DirectorAugust 15, 2018August 16, 2018

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

AN2 Therapeutics, Inc.

Report date March 19, 2026 · Filed March 23, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.91 · Expires 2032-02-17Direct16,941 Reported balance After 2026-03-19 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-03-19 · Grant · Acquired 16,941 · Balance 16,941

F1: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2: The option is fully vested.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $9.31 · Expires 2032-02-17Direct0 Reported balance After 2026-03-19 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-03-19 · Disposition to issuer · Disposed 16,941 · Balance 0

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2: The option is fully vested.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.91 · Expires 2032-05-11Direct10,362 Reported balance After 2026-03-19 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-03-19 · Grant · Acquired 10,362 · Balance 10,362

F1: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2: The option is fully vested.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.28 · Expires 2032-05-11Direct0 Reported balance After 2026-03-19 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-03-19 · Disposition to issuer · Disposed 10,362 · Balance 0

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2: The option is fully vested.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $3.91 · Expires 2033-06-06Direct23,742 Reported balance After 2026-03-19 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-03-19 · Grant · Acquired 23,742 · Balance 23,742

F1: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2: The option is fully vested.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.91 · Expires 2033-06-06Direct0 Reported balance After 2026-03-19 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-03-19 · Disposition to issuer · Disposed 23,742 · Balance 0

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2: The option is fully vested.

Filing footnotes · ownership attribution and instrument terms

F1: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F2: The option is fully vested.

F3: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

MEDICINES CO /DE

Report date May 25, 2018 · Filed May 29, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect53,133 Ending reported balance After 2018-05-25 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2018-05-25 · Exercise / conversion · Acquired 7,500 · Balance 60,633

Row 2 · 2018-05-25 · Sale · Disposed 7,500 · Balance 53,133

Stock Option (right-to-buy)SEC Table II · derivative / convertible security · Conversion / exercise price $18.30 · Expires 2018-05-29Direct0 Reported balance After 2018-05-25 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2018-05-25 · Exercise / conversion · Disposed 7,500 · Balance 0

F1: This option vested in twelve equal monthly installments beginning June 29, 2008.

Filing footnotes · ownership attribution and instrument terms

F1: This option vested in twelve equal monthly installments beginning June 29, 2008.

SYNERGY PHARMACEUTICALS, INC.

Report date August 15, 2018 · Filed August 16, 2018

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect48,305 Ending reported balance After 2018-08-15 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2018-08-15 · Exercise / conversion · Acquired 150,000 · Balance 150,000

Row 2 · 2018-08-15 · Tax withholding · Disposed 101,695 · Balance 48,305

F1: Represents the number of shares forfeited to the Company in payment of the exercise price of the stock options.

Stock OptionsSEC Table II · derivative / convertible security · Conversion / exercise price $1.20 · Expires 2018-08-21Direct474,364 Reported balance After 2018-08-15 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2018-08-15 · Exercise / conversion · Disposed 150,000 · Balance 474,364

F2: Options became exercisable on 8/21/2009, 2010 and 2011.

Filing footnotes · ownership attribution and instrument terms

F1: Represents the number of shares forfeited to the Company in payment of the exercise price of the stock options.

F2: Options became exercisable on 8/21/2009, 2010 and 2011.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 19, 2026 Filed Mar 23, 2026 23:04 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 Disposition to issuerStock Option (right to buy) · Derivative 23,742 Not disclosed Strike: $5.91 Not disclosed
Disclosure

SEC source: 0001193125-26-120207 · ownership.xml · derivative · entry 6

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 23,742 shares

Expires 2033-06-06

F3 · price: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2 · derivative.exercise_date: The option is fully vested.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 23:04 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (right to buy) · Derivative 23,742 Not disclosed Strike: $3.91 Not disclosed
Disclosure

SEC source: 0001193125-26-120207 · ownership.xml · derivative · entry 5

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,742

Underlying: Common Stock · 23,742 shares

Expires 2033-06-06

F1 · derivative.exercise_price: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F3 · price: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2 · derivative.exercise_date: The option is fully vested.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 23:04 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 Disposition to issuerStock Option (right to buy) · Derivative 10,362 Not disclosed Strike: $17.28 Not disclosed
Disclosure

SEC source: 0001193125-26-120207 · ownership.xml · derivative · entry 4

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F3 · price: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2 · derivative.exercise_date: The option is fully vested.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 23:04 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (right to buy) · Derivative 10,362 Not disclosed Strike: $3.91 Not disclosed
Disclosure

SEC source: 0001193125-26-120207 · ownership.xml · derivative · entry 3

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_price: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F3 · price: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2 · derivative.exercise_date: The option is fully vested.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 23:04 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 Disposition to issuerStock Option (right to buy) · Derivative 16,941 Not disclosed Strike: $9.31 Not disclosed
Disclosure

SEC source: 0001193125-26-120207 · ownership.xml · derivative · entry 2

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 16,941 shares

Expires 2032-02-17

F3 · price: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2 · derivative.exercise_date: The option is fully vested.

Read SEC document
March 19, 2026 Filed Mar 23, 2026 23:04 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (right to buy) · Derivative 16,941 Not disclosed Strike: $3.91 Not disclosed
Disclosure

SEC source: 0001193125-26-120207 · ownership.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,941

Underlying: Common Stock · 16,941 shares

Expires 2032-02-17

F1 · derivative.exercise_price: The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the "Premium End Date" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The "Premium End Date" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability.

F3 · price: On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged.

F2 · derivative.exercise_date: The option is fully vested.

Read SEC document
February 20, 2026 Filed Feb 23, 2026 21:21 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (Right to Buy) · Derivative 20,400 $0.00 Strike: $1.04 $0.00
Disclosure

SEC source: 0001193125-26-064061 · ownership.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,400

Underlying: Common Stock · 20,400 shares

Expires 2036-02-19

F1 · derivative.exercise_date: The option shares shall vest on February 20, 2027, subject to the Reporting Person providing continuous service through such date.

Read SEC document
May 22, 2025 Filed May 23, 2025 20:57 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (Right to Buy) · Derivative 19,111 $0.00 Strike: $1.19 $0.00
Disclosure

SEC source: 0000950170-25-077058 · ownership.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,111

Underlying: Common Stock · 19,111 shares

Expires 2035-05-21

F1 · derivative.exercise_date: The option shares shall vest on March 31, 2026, subject to the Reporting Person providing continuous service through such date.

Read SEC document
June 19, 2024 Filed Jun 21, 2024 21:58 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (Right to Buy) · Derivative 64,503 $0.00 Strike: $2.00 $0.00
Disclosure

SEC source: 0000950170-24-076374 · ownership.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,503

Underlying: Common Stock · 64,503 shares

Expires 2034-06-18

F1 · derivative.exercise_date: The option shares shall vest on the earlier of (a) the one-year anniversary of June 19, 2024 or (b) the day prior to the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person providing continuous service through such vesting date.

Read SEC document
June 07, 2023 Filed Jun 10, 2023 00:37 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (right to buy) · Derivative 23,742 $0.00 Strike: $5.91 $0.00
Disclosure

SEC source: 0000899243-23-015310 · doc4.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,742

Underlying: Common Stock · 23,742 shares

Expires 2033-06-06

F1 · derivative.exercise_date: The option shares shall vest on the earlier of (a) the one-year anniversary of June 7, 2023 or (b) the day prior to the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person providing continuous service through such vesting date.

Read SEC document
May 12, 2022 Filed May 17, 2022 01:18 UTC AN2 Therapeutics, Inc. ANTX · Entity 1085 GrantStock Option (right to buy) · Derivative 10,362 $0.00 Strike: $17.28 $0.00
Disclosure

SEC source: 0000899243-22-018281 · doc4.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,362

Underlying: Common Stock · 10,362 shares

Expires 2032-05-11

F1 · derivative.exercise_date: The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022.

Read SEC document
August 15, 2018 Filed Aug 16, 2018 17:00 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 Exercise / conversionStock Options · Derivative 150,000 $0.00 Strike: $1.20 $0.00
Disclosure

SEC source: 0001104659-18-052475 · a4.xml · derivative · entry 3

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 474,364

Underlying: Common Stock · 150,000 shares

Expires 2018-08-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Options became exercisable on 8/21/2009, 2010 and 2011.

Read SEC document
August 15, 2018 Filed Aug 16, 2018 17:00 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 Tax withholdingCommon Stock 101,695 $0.00 $0.00
Disclosure

SEC source: 0001104659-18-052475 · a4.xml · nonDerivative · entry 2

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,305

F1 · shares: Represents the number of shares forfeited to the Company in payment of the exercise price of the stock options.

Read SEC document
August 15, 2018 Filed Aug 16, 2018 17:00 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 Exercise / conversionCommon Stock 150,000 $1.20 $180,000.00
Disclosure

SEC source: 0001104659-18-052475 · a4.xml · nonDerivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 16, 2018 Filed Jun 19, 2018 16:32 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 GrantStock Options · Derivative 114,750 $0.00 Strike: $1.80 $0.00
Disclosure

SEC source: 0001104659-18-041066 · a4.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 624,364

Underlying: Common Stock · 114,750 shares

Expires 2028-06-16

F1 · shares: Represents the annual grant of stock options to each outside independent board member of the issuer.

Read SEC document
May 25, 2018 Filed May 29, 2018 17:03 UTC MEDICINES CO /DE MDCO · Entity 152552 Exercise / conversionStock Option (right-to-buy) · Derivative 7,500 $0.00 Strike: $18.30 $0.00
Disclosure

SEC source: 0001179110-18-007621 · edgar.xml · derivative · entry 3

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2018-05-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: This option vested in twelve equal monthly installments beginning June 29, 2008.

Read SEC document
May 25, 2018 Filed May 29, 2018 17:03 UTC MEDICINES CO /DE MDCO · Entity 152552 SaleCommon Stock 7,500 $32.20 $241,500.00
Disclosure

SEC source: 0001179110-18-007621 · edgar.xml · nonDerivative · entry 2

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,133

Read SEC document
May 25, 2018 Filed May 29, 2018 17:03 UTC MEDICINES CO /DE MDCO · Entity 152552 Exercise / conversionCommon Stock 7,500 $18.30 $137,250.00
Disclosure

SEC source: 0001179110-18-007621 · edgar.xml · nonDerivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,633

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 28, 2017 Filed Jun 30, 2017 17:08 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 GrantStock Options · Derivative 12,000 $0.00 Strike: $1.40 $0.00
Disclosure

SEC source: 0001104659-17-043012 · a4.xml · derivative · entry 3

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 509,614

Underlying: Common Stock · 12,000 shares

Expires 2019-11-20

F1 · shares: The reported transactions with this same footnote involved an amendment of an outstanding option, resulting in the deemed cancellation of the old option and the grant of a replacement option. The old option was originally granted on November 20, 2009. The vesting schedule of the old option was reported on a Form 3 filed by the reporting person on August 3, 2011.

Read SEC document
June 28, 2017 Filed Jun 30, 2017 17:08 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 Disposition to issuerStock Options · Derivative 12,000 $0.00 Strike: $1.40 $0.00
Disclosure

SEC source: 0001104659-17-043012 · a4.xml · derivative · entry 2

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 497,614

Underlying: Common Stock · 12,000 shares

Expires 2019-11-20

F1 · shares: The reported transactions with this same footnote involved an amendment of an outstanding option, resulting in the deemed cancellation of the old option and the grant of a replacement option. The old option was originally granted on November 20, 2009. The vesting schedule of the old option was reported on a Form 3 filed by the reporting person on August 3, 2011.

F1 · derivative.exercise_date: The reported transactions with this same footnote involved an amendment of an outstanding option, resulting in the deemed cancellation of the old option and the grant of a replacement option. The old option was originally granted on November 20, 2009. The vesting schedule of the old option was reported on a Form 3 filed by the reporting person on August 3, 2011.

Read SEC document
June 28, 2017 Filed Jun 30, 2017 17:08 UTC SYNERGY PHARMACEUTICALS, INC. SGYP · Entity 164269 GrantStock Options · Derivative 62,500 $0.00 Strike: $4.50 $0.00
Disclosure

SEC source: 0001104659-17-043012 · a4.xml · derivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 509,614

Underlying: Common Stock · 62,500 shares

Expires 2027-06-28

Read SEC document
May 25, 2017 Filed May 30, 2017 19:40 UTC MEDICINES CO /DE MDCO · Entity 152552 GrantStock Option (right-to-buy · Derivative 8,577 $0.00 Strike: $39.39 $0.00
Disclosure

SEC source: 0001179110-17-008214 · edgar.xml · derivative · entry 2

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,577

Underlying: Common Stock · 8,577 shares

Expires 2027-05-25

F2 · derivative.exercise_date: This option vests in one installment on May 25, 2018 and is made as part of and pursuant to Issuer's director compensation package.

Read SEC document
May 25, 2017 Filed May 30, 2017 19:40 UTC MEDICINES CO /DE MDCO · Entity 152552 GrantCommon Stock 3,237 $0.00 $0.00
Disclosure

SEC source: 0001179110-17-008214 · edgar.xml · nonDerivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,133

F1 · shares: This restricted stock award vests on May 25, 2018 and is made as part of and pursuant to Issuer's director compensation package.

Read SEC document
May 23, 2017 Filed May 25, 2017 17:08 UTC MEDICINES CO /DE MDCO · Entity 152552 Exercise / conversionStock Option (right-to-buy) · Derivative 7,500 Not disclosed Strike: $19.60 Not disclosed
Disclosure

SEC source: 0001179110-17-008011 · edgar.xml · derivative · entry 2

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 7,500 shares

Expires 2017-05-24

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · price: Not applicable.

F1 · derivative.exercise_date: This option vested in twelve equal monthly installments beginning on June 24, 2007.

Read SEC document
May 23, 2017 Filed May 25, 2017 17:08 UTC MEDICINES CO /DE MDCO · Entity 152552 Exercise / conversionCommon Stock 7,500 $19.60 $147,000.00
Disclosure

SEC source: 0001179110-17-008011 · edgar.xml · nonDerivative · entry 1

Spigelman Melvin K · CIK 0001339901 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,896

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.