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Nasdaq · USD

ALNY

ALNYLAM PHARMACEUTICALS, INC.

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3132
SEC CIK
0001178670
Parsed reports
483

Last 12 months

Inside the activity.

0 purchase rows · 279 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025031
Dec 202500
Jan 20260111
Feb 2026011
Mar 20260106
Apr 2026014
May 202600
Jun 202605
Jul 202600
Aug 202600
Sep 202600
Oct 202601

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
June 25, 2024 Filed Jun 26, 2024 20:26 UTC
Fitzgerald Kevin JosephCSO & EVP, Head of Research
SaleCommon Stock 45 $221.71 $9,976.95
Disclosure

SEC source: 0001735276-24-000065 · edgardoc.xml · nonDerivative · entry 2

Fitzgerald Kevin Joseph · CIK 0001886431 · CSO & EVP, Head of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,334

F2 · kind: Represents shares automatically sold by the Company on behalf of the reporting person pursuant to a mandatory sell-to-cover provision in the award agreement required to cover minimum statutory tax withholding obligations that became due upon the vesting and settlement of restricted stock units reported in this form.

F3 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $221.37 to $222.00. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
June 25, 2024 Filed Jun 27, 2024 20:04 UTC Exercise / conversionStock Option (right to buy) · Derivative 8,500 $0.00 Strike: $131.21 $0.00
Disclosure

SEC source: 0001735276-24-000072 · edgardoc.xml · derivative · entry 3

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,750

Underlying: Common Stock · 8,500 shares

Expires 2025-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024.

F2 · derivative.exercise_date: This stock option was fully vested and exercisable as of June 1, 2016.

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June 25, 2024 Filed Jun 27, 2024 20:04 UTC SaleCommon Stock 8,500 $240.00 $2,040,000.00
Disclosure

SEC source: 0001735276-24-000072 · edgardoc.xml · nonDerivative · entry 2

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,436

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024.

Read SEC document
June 25, 2024 Filed Jun 27, 2024 20:04 UTC Exercise / conversionCommon Stock 8,500 $131.21 $1,115,285.00
Disclosure

SEC source: 0001735276-24-000072 · edgardoc.xml · nonDerivative · entry 1

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,936

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC Exercise / conversionStock Option (right to buy) · Derivative 17,560 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · derivative · entry 10

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,440

Underlying: Common Stock · 17,560 shares

Expires 2025-12-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

F5 · derivative.exercise_date: This stock option was fully vested and exercisable as of December 18, 2018.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC Exercise / conversionStock Option (right to buy) · Derivative 7,470 $0.00 Strike: $71.99 $0.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · derivative · entry 9

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,780

Underlying: Common Stock · 7,470 shares

Expires 2027-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

F4 · derivative.exercise_date: This stock option was fully vested and exercisable as of June 2, 2018.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC Exercise / conversionStock Option (right to buy) · Derivative 7,420 $0.00 Strike: $70.20 $0.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · derivative · entry 8

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,830

Underlying: Common Stock · 7,420 shares

Expires 2026-06-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

F3 · derivative.exercise_date: This stock option was fully vested and exercisable as of June 3, 2017.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC SaleCommon Stock 7,470 $222.00 $1,658,340.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 6

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 136

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC SaleCommon Stock 7,420 $221.00 $1,639,820.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 5

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,606

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC SaleCommon Stock 17,560 $220.00 $3,863,200.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 4

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,026

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC Exercise / conversionCommon Stock 7,470 $71.99 $537,765.30
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 3

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,586

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC Exercise / conversionCommon Stock 7,420 $70.20 $520,884.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 2

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,116

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC Exercise / conversionCommon Stock 17,560 $88.95 $1,561,962.00
Disclosure

SEC source: 0001735276-24-000070 · edgardoc.xml · nonDerivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,696

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported on this Form 4 were made pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on August 11, 2023.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:28 UTC
Garg PushkalCMO & EVP Dev & Med Affairs
GrantCommon Stock 4,295 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000069 · edgardoc.xml · nonDerivative · entry 1

Garg Pushkal · CIK 0001829252 · CMO & EVP Dev & Med Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,712

F1 · kind: On February 23, 2022, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of one-third of the shares subject to the PSU based on the issuer publicly reporting of a positive, statistically significant result on a clinical outcomes endpoint from a Phase 3 clinical study in ATTR amyloidosis with cardiomyopathy, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on June 24, 2024.

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June 24, 2024 Filed Jun 26, 2024 20:27 UTC
Greenstreet YvonneDirector · Chief Executive Officer
GrantCommon Stock 16,953 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000068 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 88,835

F1 · kind: On February 23, 2022, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of one-third of the shares subject to the PSU based on the issuer publicly reporting of a positive, statistically significant result on a clinical outcomes endpoint from a Phase 3 clinical study in ATTR amyloidosis with cardiomyopathy, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on June 24, 2024.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:26 UTC
Poulton Jeffrey V.EVP, Chief Financial Officer
GrantCommon Stock 3,278 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000067 · edgardoc.xml · nonDerivative · entry 1

Poulton Jeffrey V. · CIK 0001782962 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,497

F1 · kind: On February 23, 2022, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of one-third of the shares subject to the PSU based on the issuer publicly reporting of a positive, statistically significant result on a clinical outcomes endpoint from a Phase 3 clinical study in ATTR amyloidosis with cardiomyopathy, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on June 24, 2024.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:26 UTC
Tanguler TolgaEVP, Chief Commercial Officer
GrantCommon Stock 3,278 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000066 · edgardoc.xml · nonDerivative · entry 1

Tanguler Tolga · CIK 0001849458 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,265

F1 · kind: On February 23, 2022, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of one-third of the shares subject to the PSU based on the issuer publicly reporting of a positive, statistically significant result on a clinical outcomes endpoint from a Phase 3 clinical study in ATTR amyloidosis with cardiomyopathy, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on June 24, 2024.

Read SEC document
June 24, 2024 Filed Jun 26, 2024 20:26 UTC
Fitzgerald Kevin JosephCSO & EVP, Head of Research
GrantCommon Stock 2,498 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000065 · edgardoc.xml · nonDerivative · entry 1

Fitzgerald Kevin Joseph · CIK 0001886431 · CSO & EVP, Head of Research

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,379

F1 · kind: On February 23, 2022, the reporting person was granted a performance-based stock unit (PSU) under the 2018 Stock Incentive Plan. The shares subject to the PSU vest based on the achievement of three specified performance measures. The shares reported were issued to the reporting person upon vesting of one-third of the shares subject to the PSU based on the issuer publicly reporting of a positive, statistically significant result on a clinical outcomes endpoint from a Phase 3 clinical study in ATTR amyloidosis with cardiomyopathy, as determined by The People, Culture and Compensation Committee of the Issuer Board of Directors on June 24, 2024.

Read SEC document
May 29, 2024 Filed May 31, 2024 23:00 UTC Exercise / conversionStock Option (right to buy) · Derivative 30,000 $0.00 Strike: $66.83 $0.00
Disclosure

SEC source: 0001735276-24-000058 · edgardoc.xml · derivative · entry 5

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2024-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects shares sold to cover option cost and tax obligations upon the option exercise pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024. The 30,000 options exercised by the reporting person were due to expire on July 1, 2024.

F4 · derivative.exercise_date: This stock option was fully vested and exercisable as of July 1, 2017.

Read SEC document
May 29, 2024 Filed May 31, 2024 23:00 UTC SaleCommon Stock 63 $149.76 $9,434.88
Disclosure

SEC source: 0001735276-24-000058 · edgardoc.xml · nonDerivative · entry 4

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,436

F1 · kind: Reflects shares sold to cover option cost and tax obligations upon the option exercise pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024. The 30,000 options exercised by the reporting person were due to expire on July 1, 2024.

Read SEC document
May 29, 2024 Filed May 31, 2024 23:00 UTC SaleCommon Stock 11,516 $148.93 $1,715,077.88
Disclosure

SEC source: 0001735276-24-000058 · edgardoc.xml · nonDerivative · entry 3

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,499

F1 · kind: Reflects shares sold to cover option cost and tax obligations upon the option exercise pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024. The 30,000 options exercised by the reporting person were due to expire on July 1, 2024.

F3 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $148.63 to $149.52. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
May 29, 2024 Filed May 31, 2024 23:00 UTC SaleCommon Stock 10,121 $148.21 $1,500,033.41
Disclosure

SEC source: 0001735276-24-000058 · edgardoc.xml · nonDerivative · entry 2

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,015

F1 · kind: Reflects shares sold to cover option cost and tax obligations upon the option exercise pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024. The 30,000 options exercised by the reporting person were due to expire on July 1, 2024.

F2 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $147.62 to $148.60. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
May 29, 2024 Filed May 31, 2024 23:00 UTC Exercise / conversionCommon Stock 30,000 $66.83 $2,004,900.00
Disclosure

SEC source: 0001735276-24-000058 · edgardoc.xml · nonDerivative · entry 1

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,136

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects shares sold to cover option cost and tax obligations upon the option exercise pursuant to a Rule 10b5-1(c) trading plan adopted by the reporting person on February 28, 2024. The 30,000 options exercised by the reporting person were due to expire on July 1, 2024.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:11 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000055 · edgardoc.xml · derivative · entry 1

PYOTT DAVID E I · CIK 0001051578 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:10 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000054 · edgardoc.xml · derivative · entry 1

KELLOGG PETER N · CIK 0001226287 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:09 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000053 · edgardoc.xml · derivative · entry 1

Bertozzi Carolyn R · CIK 0001698766 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:08 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000052 · edgardoc.xml · derivative · entry 1

Sigal Charles Elliott · CIK 0001661908 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:07 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000051 · edgardoc.xml · derivative · entry 1

BRANDICOURT OLIVIER · CIK 0001508518 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:06 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000050 · edgardoc.xml · derivative · entry 1

HAMBURG MARGARET A · CIK 0001266917 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:06 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000049 · edgardoc.xml · derivative · entry 1

Reitan Colleen F · CIK 0001740730 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:04 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000047 · edgardoc.xml · derivative · entry 1

SCHULMAN AMY W · CIK 0001438226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:05 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000048 · edgardoc.xml · derivative · entry 1

BONNEY MICHAEL W · CIK 0001219016 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:02 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000045 · edgardoc.xml · derivative · entry 1

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
May 16, 2024 Filed May 20, 2024 20:03 UTC GrantStock Option (right to buy) · Derivative 5,228 $0.00 Strike: $151.22 $0.00
Disclosure

SEC source: 0001735276-24-000046 · edgardoc.xml · derivative · entry 1

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,228

Underlying: Common Stock · 5,228 shares

Expires 2034-05-16

F1 · derivative.exercise_date: This award vests in full upon the earlier of the first anniversary of the grant date and the date of any earlier retirement or resignation of the Reporting Person, provided such date of retirement or resignation occurs no more than 90 days prior to the first anniversary of the grant date.

Read SEC document
March 01, 2024 Filed Mar 5, 2024 21:22 UTC
Tanguler TolgaEVP, Chief Commercial Officer
GrantStock Option (right to buy) · Derivative 9,279 $0.00 Strike: $152.61 $0.00
Disclosure

SEC source: 0001735276-24-000030 · edgardoc.xml · derivative · entry 2

Tanguler Tolga · CIK 0001849458 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,279

Underlying: Common Stock · 9,279 shares

Expires 2034-03-01

F3 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vesting in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

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March 01, 2024 Filed Mar 5, 2024 21:22 UTC
Tanguler TolgaEVP, Chief Commercial Officer
GrantCommon Stock 4,751 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000030 · edgardoc.xml · nonDerivative · entry 1

Tanguler Tolga · CIK 0001849458 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,987

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

F2 · balance_after: The Reporting Person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 4,751 newly awarded RSUs and 5,236 shares of common stock. The Reporting Person also holds 3,333 unvested RSUs that were previously reported in Table II.

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March 01, 2024 Filed Mar 5, 2024 21:21 UTC
Garg PushkalCMO & EVP Dev & Med Affairs
GrantStock Option (right to buy) · Derivative 9,279 $0.00 Strike: $152.61 $0.00
Disclosure

SEC source: 0001735276-24-000029 · edgardoc.xml · derivative · entry 4

Garg Pushkal · CIK 0001829252 · CMO & EVP Dev & Med Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,279

Underlying: Common Stock · 9,279 shares

Expires 2034-03-01

F5 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vesting in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

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March 01, 2024 Filed Mar 5, 2024 21:21 UTC
Garg PushkalCMO & EVP Dev & Med Affairs
GrantCommon Stock 4,751 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000029 · edgardoc.xml · nonDerivative · entry 1

Garg Pushkal · CIK 0001829252 · CMO & EVP Dev & Med Affairs

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,417

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

F2 · balance_after: The Reporting Person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 4,751 newly awarded RSUs and 8,666 shares of common stock. The Reporting Person also holds 3,816 unvested RSUs that were previously reported in Table II.

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March 01, 2024 Filed Mar 5, 2024 21:21 UTC
Poulton Jeffrey V.EVP, Chief Financial Officer
GrantStock Option (right to buy) · Derivative 15,118 $0.00 Strike: $152.61 $0.00
Disclosure

SEC source: 0001735276-24-000028 · edgardoc.xml · derivative · entry 3

Poulton Jeffrey V. · CIK 0001782962 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,118

Underlying: Common Stock · 15,118 shares

Expires 2034-03-01

F4 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vesting in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

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March 01, 2024 Filed Mar 5, 2024 21:21 UTC
Poulton Jeffrey V.EVP, Chief Financial Officer
GrantCommon Stock 7,741 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000028 · edgardoc.xml · nonDerivative · entry 1

Poulton Jeffrey V. · CIK 0001782962 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,219

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

F2 · balance_after: The Reporting Person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 7,741 newly awarded RSUs and 19,478 shares of common stock. The Reporting Person also holds 3,816 unvested RSUs that were previously reported in Table II.

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March 01, 2024 Filed Mar 5, 2024 21:20 UTC
Greenstreet YvonneDirector · Chief Executive Officer
GrantStock Option (right to buy) · Derivative 46,394 $0.00 Strike: $152.61 $0.00
Disclosure

SEC source: 0001735276-24-000027 · edgardoc.xml · derivative · entry 3

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 46,394

Underlying: Common Stock · 46,394 shares

Expires 2034-03-01

F4 · derivative.exercise_date: The stock option vests as to 25% of the shares on the first anniversary of the grant date and the remaining shares vesting in equal installments at the end of each successive three-month period thereafter until the fourth anniversary of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

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March 01, 2024 Filed Mar 5, 2024 21:20 UTC
Greenstreet YvonneDirector · Chief Executive Officer
GrantCommon Stock 23,754 $0.00 $0.00
Disclosure

SEC source: 0001735276-24-000027 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,882

F1 · shares: These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

F2 · balance_after: The Reporting Person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 23,754 newly awarded RSUs and 48,128 shares of common stock. The Reporting Person also holds 11,842 unvested RSUs that were previously reported in Table II.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC Exercise / conversionStock Option (right to buy) · Derivative 30,000 $0.00 Strike: $59.25 $0.00
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · derivative · entry 9

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC SaleCommon Stock 516 $156.54 $80,774.64
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 7

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

F7 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $156.15 to $156.98. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC SaleCommon Stock 101 $154.07 $15,561.07
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 6

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 516

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

F6 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $154.06 to $154.99. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC SaleCommon Stock 1,906 $153.62 $292,799.72
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 5

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 617

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

F5 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $153.04 to $154.03. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC SaleCommon Stock 915 $152.40 $139,446.00
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 4

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,523

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

F4 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $152.02 to $152.91. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC SaleCommon Stock 13,557 $151.43 $2,052,936.51
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 3

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,438

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

F3 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $151.01 to $151.99. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC SaleCommon Stock 13,005 $150.60 $1,958,553.00
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 2

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,995

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

F2 · price: The price reported represents the weighted average sales price of shares sold in multiple transactions at prices ranging from $150.00 to $151.00. The reporting person will provide to the issuer, any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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February 29, 2024 Filed Mar 1, 2024 21:12 UTC Exercise / conversionCommon Stock 30,000 $59.25 $1,777,500.00
Disclosure

SEC source: 0001735276-24-000022 · edgardoc.xml · nonDerivative · entry 1

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 16, 2023. The 30,000 options exercised and sold by the reporting person were due to expire on June 4, 2024.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.