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person · Reporting owner

Lee Jennifer Kayden

Disclosed activity across 2 companies

Tapewire entity
23364
SEC CIK
0001801372

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Krystal Biotech, Inc.KRYS · Entity 3500Chief Commercial OfficerJanuary 31, 2020February 04, 2020
RHYTHM PHARMACEUTICALS, INC.RYTM · Entity 3693EVP, Head of North AmericaAugust 13, 2026August 14, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Krystal Biotech, Inc.

Report date January 31, 2020 · Filed February 04, 2020

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $52.26 · Expires 2030-01-30Direct125,000 Reported balance After 2020-01-31 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2020-01-31 · Grant · Acquired 125,000 · Balance 125,000

F1: The options vest ratably over a four-year period beginning on January 20, 2020.

Filing footnotes · ownership attribution and instrument terms

F1: The options vest ratably over a four-year period beginning on January 20, 2020.

RHYTHM PHARMACEUTICALS, INC.

Report date August 13, 2026 · Filed August 14, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Ending reported balance After 2026-08-13 transaction · row 3
3 source rows · reconciled sequence

Row 1 · 2026-08-13 · Exercise / conversion · Acquired 35,000 · Balance 54,233

F1: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

Row 2 · 2026-08-13 · Exercise / conversion · Acquired 21,601 · Balance 75,834

F1: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

Row 3 · 2026-08-13 · Sale · Disposed 75,834 · Balance 0

F1: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

Stock Options (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $24.29 · Expires 2030-11-09Direct36,283 Reported balance After 2026-08-13 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2026-08-13 · Exercise / conversion · Disposed 35,000 · Balance 36,283

F1: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

F2: The stock options were granted on November 9, 2020. 25% of the shares subject to the option vested and become exercisable on November 9, 2021 and the remaining 75% of the shares subject to the option vested and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.

Stock Options (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $6.80 · Expires 2032-02-08Direct0 Reported balance After 2026-08-13 transaction · row 5 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 5 · 2026-08-13 · Exercise / conversion · Disposed 21,601 · Balance 0

F1: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

F3: The stock options were granted on February 9, 2022. The options vested and became exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Filing footnotes · ownership attribution and instrument terms

F1: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

F2: The stock options were granted on November 9, 2020. 25% of the shares subject to the option vested and become exercisable on November 9, 2021 and the remaining 75% of the shares subject to the option vested and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.

F3: The stock options were granted on February 9, 2022. The options vested and became exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
August 13, 2026 Filed Aug 14, 2026 23:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionStock Options (Right to Buy) · Derivative 21,601 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001649904-26-000009 · form4.xml · derivative · entry 5

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 21,601 shares

Expires 2032-02-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

F3 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vested and became exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
August 13, 2026 Filed Aug 14, 2026 23:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionStock Options (Right to Buy) · Derivative 35,000 $0.00 Strike: $24.29 $0.00
Disclosure

SEC source: 0001649904-26-000009 · form4.xml · derivative · entry 4

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,283

Underlying: Common Stock · 35,000 shares

Expires 2030-11-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

F2 · derivative.exercise_date: The stock options were granted on November 9, 2020. 25% of the shares subject to the option vested and become exercisable on November 9, 2021 and the remaining 75% of the shares subject to the option vested and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.

Read SEC document
August 13, 2026 Filed Aug 14, 2026 23:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 75,834 $117.38 $8,901,531.42
Disclosure

SEC source: 0001649904-26-000009 · form4.xml · nonDerivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

Read SEC document
August 13, 2026 Filed Aug 14, 2026 23:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 21,601 $6.80 $146,886.80
Disclosure

SEC source: 0001649904-26-000009 · form4.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,834

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

Read SEC document
August 13, 2026 Filed Aug 14, 2026 23:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 35,000 $24.29 $850,150.00
Disclosure

SEC source: 0001649904-26-000009 · form4.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.

Read SEC document
February 11, 2026 Filed Feb 13, 2026 22:49 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 GrantStock Options (Right to Buy) · Derivative 32,500 $0.00 Strike: $98.47 $0.00
Disclosure

SEC source: 0001104659-26-015399 · tm266366-4_4seq1.xml · derivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,500

Underlying: Common Stock · 32,500 shares

Expires 2036-02-10

F3 · derivative.exercise_date: The stock options were granted on February 11, 2026. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 11, 2026 Filed Feb 13, 2026 22:49 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 GrantRestricted Stock Units · Derivative 21,650 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-015399 · tm266366-4_4seq1.xml · derivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,650

Underlying: Common Stock · 21,650 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 1, 2027, February 1, 2028, February 1, 2029 and February 1, 2030. The restricted stock units have no expiration date.

F2 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 1, 2027, February 1, 2028, February 1, 2029 and February 1, 2030. The restricted stock units have no expiration date.

Read SEC document
February 01, 2026 Filed Feb 3, 2026 21:33 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 9,163 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-009767 · tm264963-4_4seq1.xml · derivative · entry 6

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,487

Underlying: Common Stock · 9,163 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F6 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 1, 2026, February 1, 2027, February 1, 2028 and February 1, 2029. The restricted stock units have no expiration date.

F6 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 1, 2026, February 1, 2027, February 1, 2028 and February 1, 2029. The restricted stock units have no expiration date.

Read SEC document
February 01, 2026 Filed Feb 3, 2026 21:33 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 5,500 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-009767 · tm264963-4_4seq1.xml · derivative · entry 5

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,000

Underlying: Common Stock · 5,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F5 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 16, 2025, February 1, 2026, February 1, 2027 and February 1, 2028. The restricted stock units have no expiration date.

F5 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 16, 2025, February 1, 2026, February 1, 2027 and February 1, 2028. The restricted stock units have no expiration date.

Read SEC document
February 01, 2026 Filed Feb 3, 2026 21:33 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 4,512 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-009767 · tm264963-4_4seq1.xml · derivative · entry 4

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,512

Underlying: Common Stock · 4,512 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F4 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 1, 2024, February 1, 2025, February 1, 2026 and February 1, 2027. The restricted stock units have no expiration date.

F4 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 1, 2024, February 1, 2025, February 1, 2026 and February 1, 2027. The restricted stock units have no expiration date.

Read SEC document
February 01, 2026 Filed Feb 3, 2026 21:33 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 3,437 $0.00 $0.00
Disclosure

SEC source: 0001104659-26-009767 · tm264963-4_4seq1.xml · derivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,437 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 1, 2026. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 1, 2026. The restricted stock units have no expiration date.

Read SEC document
February 01, 2026 Filed Feb 3, 2026 21:33 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Tax withholdingCommon Stock 9,237 $108.99 $1,006,740.63
Disclosure

SEC source: 0001104659-26-009767 · tm264963-4_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,233

F2 · kind: These shares were withheld for payment of the withholding taxes upon the vesting of the restricted stock units reported herein.

Read SEC document
February 01, 2026 Filed Feb 3, 2026 21:33 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 22,612 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-26-009767 · tm264963-4_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,470

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 19, 2025 Filed Feb 20, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 2,035 $57.22 $116,442.70
Disclosure

SEC source: 0001104659-25-015320 · tm257103-4_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,858

F2 · kind: The sales reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
February 16, 2025 Filed Feb 20, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 5,500 $0.00 $0.00
Disclosure

SEC source: 0001104659-25-015320 · tm257103-4_4seq1.xml · derivative · entry 5

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,500

Underlying: Common Stock · 5,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F5 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 16, 2025, February 16, 2026, February 16, 2027 and February 16, 2028. The restricted stock units have no expiration date.

F5 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 16, 2025, February 16, 2026, February 16, 2027 and February 16, 2028. The restricted stock units have no expiration date.

Read SEC document
February 16, 2025 Filed Feb 20, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 5,500 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-25-015320 · tm257103-4_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,893

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 14, 2025 Filed Feb 20, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 GrantStock Options (Right to Buy) · Derivative 55,000 $0.00 Strike: $56.69 $0.00
Disclosure

SEC source: 0001104659-25-015320 · tm257103-4_4seq1.xml · derivative · entry 4

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,000

Underlying: Common Stock · 55,000 shares

Expires 2035-02-13

F4 · derivative.exercise_date: The stock options were granted on February 14, 2025. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 14, 2025 Filed Feb 20, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 GrantRestricted Stock Units · Derivative 36,650 $0.00 $0.00
Disclosure

SEC source: 0001104659-25-015320 · tm257103-4_4seq1.xml · derivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,650

Underlying: Common Stock · 36,650 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 14, 2026, February 14, 2027, February 14, 2028 and February 14, 2029. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 14, 2026, February 14, 2027, February 14, 2028 and February 14, 2029. The restricted stock units have no expiration date.

Read SEC document
February 13, 2025 Filed Feb 14, 2025 21:55 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,205 $58.00 $69,890.00
Disclosure

SEC source: 0001104659-25-014257 · tm256729-1_4seq1.xml · nonDerivative · entry 4

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,393

F2 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

Read SEC document
February 12, 2025 Filed Feb 14, 2025 21:55 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,205 $56.39 $67,949.95
Disclosure

SEC source: 0001104659-25-014257 · tm256729-1_4seq1.xml · nonDerivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,598

F2 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

Read SEC document
February 12, 2025 Filed Feb 14, 2025 21:55 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 10 $56.41 $564.10
Disclosure

SEC source: 0001104659-25-014257 · tm256729-1_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,803

F1 · kind: The sales reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
February 12, 2025 Filed Feb 14, 2025 21:55 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 600 $56.39 $33,834.00
Disclosure

SEC source: 0001104659-25-014257 · tm256729-1_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,813

F1 · kind: The sales reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
February 11, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 2,031 $0.00 $0.00
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · derivative · entry 10

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,031 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F8 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

F8 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

Read SEC document
February 11, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 4 $57.50 $230.00
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 7

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,413

F5 · kind: The sales reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
February 11, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,023 $57.51 $58,832.73
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 6

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,417

F5 · kind: The sales reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

Read SEC document
February 11, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 2,031 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 5

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,440

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 10, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 2,295 $59.34 $136,187.14
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 4

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,409

F2 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F4 · price: The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $59.1400 to $59.3600 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote

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February 10, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,894 $58.39 $110,595.96
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,704

F2 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F3 · price: The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $58.0750 to $58.8900 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote

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February 09, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionStock Option (Right to Buy) · Derivative 4,189 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · derivative · entry 9

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,601

Underlying: Common Stock · 4,189 shares

Expires 2032-02-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

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February 09, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 3,437 $0.00 $0.00
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · derivative · entry 8

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 3,437

Underlying: Common Stock · 3,437 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F6 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F6 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

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February 09, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 4,189 $6.80 $28,485.20
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 8,598

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 09, 2025 Filed Feb 12, 2025 02:46 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 3,437 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-25-011677 · tm256299-3_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,409

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

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February 05, 2025 Filed Feb 7, 2025 22:05 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 200 $61.95 $12,390.00
Disclosure

SEC source: 0001104659-25-010610 · tm255903-1_4seq1.xml · nonDerivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 972

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

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February 05, 2025 Filed Feb 7, 2025 22:05 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,133 $61.01 $69,129.66
Disclosure

SEC source: 0001104659-25-010610 · tm255903-1_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,172

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at per share prices ranging from $60.67 to $61.49. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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February 05, 2025 Filed Feb 7, 2025 22:05 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,733 $60.08 $104,120.55
Disclosure

SEC source: 0001104659-25-010610 · tm255903-1_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,305

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at per share prices ranging from $59.54 to $60.43. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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February 04, 2025 Filed Feb 5, 2025 02:23 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 1,447 $59.43 $85,995.21
Disclosure

SEC source: 0001104659-25-009284 · tm255457-2_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,038

F2 · kind: The sale reported in this Form 4 was effected pursuant to Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

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February 01, 2025 Filed Feb 5, 2025 02:23 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionRestricted Stock Units · Derivative 4,513 $0.00 $0.00
Disclosure

SEC source: 0001104659-25-009284 · tm255457-2_4seq1.xml · derivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,024

Underlying: Common Stock · 4,513 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 1, 2024, February 1, 2025, February 1, 2026 and February 1, 2027. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 1, 2024, February 1, 2025, February 1, 2026 and February 1, 2027. The restricted stock units have no expiration date.

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February 01, 2025 Filed Feb 5, 2025 02:23 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 4,513 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-25-009284 · tm255457-2_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,485

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionStock Option (Right to Buy) · Derivative 11,642 $0.00 Strike: $30.66 $0.00
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · derivative · entry 10

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,108

Underlying: Common Stock · 11,642 shares

Expires 2031-02-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The stock options were granted on February 11, 2021. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionStock Option (Right to Buy) · Derivative 28,717 $0.00 Strike: $24.29 $0.00
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · derivative · entry 9

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,283

Underlying: Common Stock · 28,717 shares

Expires 2030-11-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The stock options were granted on November 9, 2020. The options are fully vested.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionStock Option (Right to Buy) · Derivative 20,622 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · derivative · entry 8

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,790

Underlying: Common Stock · 20,622 shares

Expires 2032-02-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 200 $68.43 $13,686.00
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 7

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 972

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 11,070 $67.56 $747,872.60
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 6

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,172

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F4 · price: The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $67.33 to $68.3299 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 17,540 $66.95 $1,174,274.94
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 5

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,242

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F3 · price: The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $66.33 to $67.3299 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 38,051 $65.68 $2,499,048.89
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 4

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 29,782

F1 · kind: The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 8, 2024.

F2 · price: The price reported in Column 4 is a weighted average price. The securities were sold in multiple transactions at prices ranging from $65.18 to $66.1799 per common stock. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 11,642 $30.66 $356,943.72
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 3

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 67,833

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 28,717 $24.29 $697,535.93
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,191

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
November 11, 2024 Filed Nov 14, 2024 02:04 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 Exercise / conversionCommon Stock 20,622 $6.80 $140,229.60
Disclosure

SEC source: 0001104659-24-117942 · tm2428383-1_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 27,474

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 20, 2024 Filed Mar 22, 2024 20:16 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 9,066 $39.33 $356,565.78
Disclosure

SEC source: 0001104659-24-037880 · tm249484-1_4seq1.xml · nonDerivative · entry 2

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,852

F1 · kind: The sale reported in this Form 4 was effected pursuant to Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at per share prices ranging from $38.75 to $39.72. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 20, 2024 Filed Mar 22, 2024 20:16 UTC RHYTHM PHARMACEUTICALS, INC. RYTM · Entity 3693 SaleCommon Stock 9,169 $38.22 $350,439.18
Disclosure

SEC source: 0001104659-24-037880 · tm249484-1_4seq1.xml · nonDerivative · entry 1

Lee Jennifer Kayden · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,918

F1 · kind: The sale reported in this Form 4 was effected pursuant to Rule 10b5-1 instruction adopted prior to February 27, 2023 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at per share prices ranging from $37.75 to $38.68. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.