Tapewire

Nasdaq · USD

KRYS

Krystal Biotech, Inc.

Export transactions ↓
Tapewire entity
3500
SEC CIK
0001711279
Parsed reports
185

Last 12 months

Inside the activity.

0 purchase rows · 142 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 2025032
Jan 202600
Feb 2026031
Mar 2026021
Apr 202600
May 202601
Jun 2026023
Jul 202600
Aug 202608
Sep 2026026
Oct 202600

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
September 14, 2026 Filed Sep 17, 2026 00:05 UTC
ROSSI DINO ADirector
GrantRestricted Stock Units · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001209059-26-000008 · wk-form4_1789603516.xml · derivative · entry 2

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:05 UTC
ROSSI DINO ADirector
GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001209059-26-000008 · wk-form4_1789603516.xml · derivative · entry 1

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:03 UTC GrantRestricted Stock Units · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001852880-26-000002 · wk-form4_1789603389.xml · derivative · entry 2

Sutherland Everett Rand · CIK 0001852880 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:03 UTC GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001852880-26-000002 · wk-form4_1789603389.xml · derivative · entry 1

Sutherland Everett Rand · CIK 0001852880 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:02 UTC GrantRestricted Stock Units · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001967722-26-000002 · wk-form4_1789603333.xml · derivative · entry 2

Mazzacco Catherine · CIK 0001967722 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:02 UTC GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001967722-26-000002 · wk-form4_1789603333.xml · derivative · entry 1

Mazzacco Catherine · CIK 0001967722 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:01 UTC GrantRestricted Stock Units · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001836440-26-000002 · wk-form4_1789603304.xml · derivative · entry 2

Mason Christopher · CIK 0001836440 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:01 UTC GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001836440-26-000002 · wk-form4_1789603304.xml · derivative · entry 1

Mason Christopher · CIK 0001836440 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:01 UTC GrantRestricted Stock Award · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001711279-26-000060 · wk-form4_1789603273.xml · derivative · entry 2

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:01 UTC GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001711279-26-000060 · wk-form4_1789603273.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:00 UTC GrantRestricted Stock Units · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001532023-26-000002 · wk-form4_1789603228.xml · derivative · entry 2

Gangolli Julian S · CIK 0001532023 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:00 UTC GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001532023-26-000002 · wk-form4_1789603228.xml · derivative · entry 1

Gangolli Julian S · CIK 0001532023 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 399 $366.56 $146,255.84
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 13

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,302,145

F15 · price: The transaction was executed in multiple trades ranging from $366.39 to $366.91. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 826 $365.41 $301,831.88
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 12

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,302,544

F14 · price: The transaction was executed in multiple trades ranging from $365.07 to $366.03. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 1,329 $364.48 $484,390.07
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 11

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,303,370

F13 · price: The transaction was executed in multiple trades ranging from $364.07 to $365.05. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 565 $363.34 $205,287.33
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 10

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,304,699

F12 · price: The transaction was executed in multiple trades ranging from $363.05 to $364.01. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 1,992 $362.65 $722,404.18
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 9

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,305,264

F11 · price: The transaction was executed in multiple trades ranging from $362.02 to $363.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 1,242 $361.61 $449,119.62
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 8

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,307,256

F10 · price: The transaction was executed in multiple trades ranging from $361.02 to $362.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 2,320 $360.47 $836,281.12
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 7

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,308,498

F9 · price: The transaction was executed in multiple trades ranging from $360.01 to $361.005. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 3,392 $359.39 $1,219,037.99
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 6

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,310,818

F8 · price: The transaction was executed in multiple trades ranging from $358.99 to $359.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 3,180 $358.42 $1,139,776.55
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 5

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,314,210

F7 · price: The transaction was executed in multiple trades ranging from $357.99 to $358.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 3,962 $357.57 $1,416,708.98
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 4

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,317,390

F6 · price: The transaction was executed in multiple trades ranging from $356.99 to $357.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 3,267 $356.37 $1,164,253.93
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 3

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,321,352

F5 · price: The transaction was executed in multiple trades ranging from $355.98 to $356.96. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 2,006 $355.57 $713,277.23
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 2

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,324,619

F4 · price: The transaction was executed in multiple trades ranging from $354.98 to $355.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC
Krishnan SumaDirector · President, R&D · 10% owner
SaleCommon Stock 520 $354.54 $184,360.80
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 1

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,326,625

F1 · kind: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Krish S. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by her spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of her pecuniary interest therein.

F2 · price: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated.

F3 · price: The transaction was executed in multiple trades ranging from $353.98 to $354.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 405 $366.56 $148,455.46
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 13

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,347,543

F15 · price: The transaction was executed in multiple trades ranging from $366.39 to $366.91. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 847 $365.42 $309,507.61
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 12

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,347,948

F14 · price: The transaction was executed in multiple trades ranging from $365.07 to $366.03. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 1,358 $364.48 $494,963.03
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 11

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,348,795

F13 · price: The transaction was executed in multiple trades ranging from $364.07 to $365.05. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 573 $363.34 $208,195.20
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 10

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,350,153

F12 · price: The transaction was executed in multiple trades ranging from $363.05 to $364.01. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 2,010 $362.65 $728,927.30
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 9

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,350,726

F11 · price: The transaction was executed in multiple trades ranging from $362.02 to $363.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 1,214 $361.61 $438,993.45
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 8

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,352,736

F10 · price: The transaction was executed in multiple trades ranging from $361.02 to $362.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 2,266 $360.46 $816,809.16
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 7

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,353,950

F9 · price: The transaction was executed in multiple trades ranging from $360.01 to $361.005. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 3,357 $359.39 $1,206,459.14
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 6

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,356,216

F8 · price: The transaction was executed in multiple trades ranging from $358.99 to $359.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 3,143 $358.42 $1,126,508.40
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 5

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,359,573

F7 · price: The transaction was executed in multiple trades ranging from $357.99 to $358.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 3,981 $357.57 $1,423,501.30
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 4

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,362,716

F6 · price: The transaction was executed in multiple trades ranging from $356.99 to $357.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 3,297 $356.37 $1,174,947.60
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 3

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,366,697

F5 · price: The transaction was executed in multiple trades ranging from $355.98 to $356.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 2,029 $355.57 $721,455.39
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 2

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,369,994

F4 · price: The transaction was executed in multiple trades ranging from $354.98 to $355.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:14 UTC
Krishnan Krish SDirector · President and CEO · 10% owner
SaleCommon Stock 520 $354.54 $184,360.80
Disclosure

SEC source: 0001298709-26-000011 · wk-form4_1788563646.xml · nonDerivative · entry 1

Krishnan Krish S · CIK 0001298709 · Director · President and CEO · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,372,023

F1 · kind: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Suma M. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by his spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

F2 · price: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated.

F3 · price: The transaction was executed in multiple trades ranging from $353.98 to $354.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 40 $333.23 $13,329.20
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 9

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 3,095 $331.43 $1,025,786.06
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 8

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,040

F8 · price: The transaction was executed in multiple trades ranging from $331.02 to $331.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 4,896 $330.36 $1,617,422.00
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 7

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,135

F7 · price: The transaction was executed in multiple trades ranging from $330 to $330.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 7,428 $329.60 $2,448,279.94
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 6

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,031

F6 · price: The transaction was executed in multiple trades ranging from $329.01 to $329.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 1,687 $328.52 $554,205.14
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 5

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,459

F5 · price: The transaction was executed in multiple trades ranging from $328.01 to $328.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 5,226 $327.39 $1,710,960.52
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 4

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,146

F4 · price: The transaction was executed in multiple trades ranging from $327 to $327.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 2,287 $326.60 $746,940.60
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 3

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,372

F3 · price: The transaction was executed in multiple trades ranging from $326.04 to $326.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
SaleCommon Stock 341 $325.60 $111,029.09
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 2

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,659

F2 · price: The transaction was executed in multiple trades ranging from $325 to $325.96. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
August 14, 2026 Filed Aug 14, 2026 22:22 UTC
ROSSI DINO ADirector
GiftCommon Stock 3,691 $0.00 $0.00
Disclosure

SEC source: 0001209059-26-000006 · wk-form4_1786746156.xml · nonDerivative · entry 1

ROSSI DINO A · CIK 0001209059 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

F1 · kind: Represents a bona fide gift of Krystal Biotech, Inc.'s Common Stock to a charitable donor-advised fund.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 22:45 UTC
Thomas John CharlesEVP, General Counsel
Exercise / conversionStock Option (Right to Buy) · Derivative 1,000 $0.00 Strike: $179.25 $0.00
Disclosure

SEC source: 0002114900-26-000009 · wk-form4_1782513949.xml · derivative · entry 3

Thomas John Charles · CIK 0002114900 · EVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,500

Underlying: Common Stock · 1,000 shares

Expires 2035-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The options vest ratably over a four-year period beginning on February 28, 2026.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 22:45 UTC
Thomas John CharlesEVP, General Counsel
SaleCommon Stock 1,000 $347.27 $347,270.00
Disclosure

SEC source: 0002114900-26-000009 · wk-form4_1782513949.xml · nonDerivative · entry 2

Thomas John Charles · CIK 0002114900 · EVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · shares: The acquisition and sale of shares of the Company's common stock reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 23, 2026. All transactions contemplated by the plan have been completed, and the plan has terminated in accordance with its terms.

Read SEC document
June 25, 2026 Filed Jun 26, 2026 22:45 UTC
Thomas John CharlesEVP, General Counsel
Exercise / conversionCommon Stock 1,000 $179.25 $179,250.00
Disclosure

SEC source: 0002114900-26-000009 · wk-form4_1782513949.xml · nonDerivative · entry 1

Thomas John Charles · CIK 0002114900 · EVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: The acquisition and sale of shares of the Company's common stock reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on February 23, 2026. All transactions contemplated by the plan have been completed, and the plan has terminated in accordance with its terms.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.