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Nasdaq · USD

RYTM

RHYTHM PHARMACEUTICALS, INC.

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3693
SEC CIK
0001649904
Parsed reports
430

Last 12 months

Inside the activity.

0 purchase rows · 50 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202503
Dec 202501
Jan 202600
Feb 2026023
Mar 202601
Apr 202600
May 202601
Jun 202601
Jul 202600
Aug 2026015
Sep 202605
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 29, 2022 Filed Mar 31, 2022 16:31 UTC
Roberts William T.Chief Accounting Officer
SaleCommon Stock 1,023 $11.13 $11,385.99
Disclosure

SEC source: 0001104659-22-041079 · tm2211062-1_4seq1.xml · nonDerivative · entry 2

Roberts William T. · CIK 0001852360 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,477

F2 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.

Read SEC document
March 29, 2022 Filed Mar 31, 2022 16:31 UTC
Roberts William T.Chief Accounting Officer
Exercise / conversionCommon Stock 2,500 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-22-041079 · tm2211062-1_4seq1.xml · nonDerivative · entry 1

Roberts William T. · CIK 0001852360 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 15, 2022 Filed Feb 16, 2022 00:28 UTC
Lee Jennifer KaydenEVP, Head of North America
SaleCommon Stock 722 $6.10 $4,404.20
Disclosure

SEC source: 0001104659-22-023948 · tm226880-1_4seq1.xml · nonDerivative · entry 2

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,310

F2 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.

Read SEC document
February 15, 2022 Filed Feb 16, 2022 00:31 UTC
Smith Hunter CChief Financial Officer
SaleCommon Stock 833 $6.10 $5,081.30
Disclosure

SEC source: 0001104659-22-023951 · tm226880-3_4seq1.xml · nonDerivative · entry 2

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,161

F2 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.

Read SEC document
February 15, 2022 Filed Feb 16, 2022 00:32 UTC
Shulman JosephChief Technical Officer
SaleCommon Stock 557 $6.10 $3,397.70
Disclosure

SEC source: 0001104659-22-023952 · tm226880d4_4seq1.xml · nonDerivative · entry 2

Shulman Joseph · CIK 0001909855 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,006

F2 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.

Read SEC document
February 15, 2022 Filed Feb 16, 2022 00:29 UTC
Mazabraud YannEVP, Head of International
SaleCommon Stock 934 $6.10 $5,697.40
Disclosure

SEC source: 0001104659-22-023949 · tm226880-2_4seq1.xml · nonDerivative · entry 2

Mazabraud Yann · CIK 0001774702 · EVP, Head of International

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,098

F2 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:28 UTC
Lee Jennifer KaydenEVP, Head of North America
Exercise / conversionRestricted Stock Units · Derivative 2,032 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-023948 · tm226880-1_4seq1.xml · derivative · entry 3

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,093

Underlying: Common Stock · 2,032 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:28 UTC
Lee Jennifer KaydenEVP, Head of North America
Exercise / conversionCommon Stock 2,032 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-22-023948 · tm226880-1_4seq1.xml · nonDerivative · entry 1

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,032

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:31 UTC
Smith Hunter CChief Financial Officer
Exercise / conversionRestricted Stock Units · Derivative 2,344 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-023951 · tm226880-3_4seq1.xml · derivative · entry 3

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,031

Underlying: Common Stock · 2,344 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:31 UTC
Smith Hunter CChief Financial Officer
Exercise / conversionCommon Stock 2,344 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-22-023951 · tm226880-3_4seq1.xml · nonDerivative · entry 1

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,994

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:32 UTC
Shulman JosephChief Technical Officer
Exercise / conversionRestricted Stock Units · Derivative 1,563 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-023952 · tm226880d4_4seq1.xml · derivative · entry 3

Shulman Joseph · CIK 0001909855 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,687

Underlying: Common Stock · 1,563 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:32 UTC
Shulman JosephChief Technical Officer
Exercise / conversionCommon Stock 1,563 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-22-023952 · tm226880d4_4seq1.xml · nonDerivative · entry 1

Shulman Joseph · CIK 0001909855 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,563

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:29 UTC
Mazabraud YannEVP, Head of International
Exercise / conversionRestricted Stock Units · Derivative 2,032 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-023949 · tm226880-2_4seq1.xml · derivative · entry 3

Mazabraud Yann · CIK 0001774702 · EVP, Head of International

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,093

Underlying: Common Stock · 2,032 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest or have vested as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date.

Read SEC document
February 11, 2022 Filed Feb 16, 2022 00:29 UTC
Mazabraud YannEVP, Head of International
Exercise / conversionCommon Stock 2,032 Not disclosed Not disclosed
Disclosure

SEC source: 0001104659-22-023949 · tm226880-2_4seq1.xml · nonDerivative · entry 1

Mazabraud Yann · CIK 0001774702 · EVP, Head of International

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,032

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 09, 2022 Filed Feb 11, 2022 21:34 UTC
Manning Linda ShapiroChief Medical Officer
GrantRestricted Stock Units · Derivative 12,500 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020894 · tm226394-5_4seq1.xml · derivative · entry 2

Manning Linda Shapiro · CIK 0001883256 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
February 09, 2022 Filed Feb 11, 2022 21:34 UTC
Manning Linda ShapiroChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020894 · tm226394-5_4seq1.xml · derivative · entry 1

Manning Linda Shapiro · CIK 0001883256 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2032-02-08

F1 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:32 UTC
Cramer Pamela J.Chief Human Resources Officer
GrantRestricted Stock Units · Derivative 9,375 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020889 · tm226394-2_4seq1.xml · derivative · entry 2

Cramer Pamela J. · CIK 0001873517 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,375

Underlying: Common Stock · 9,375 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:32 UTC
Cramer Pamela J.Chief Human Resources Officer
GrantStock Option (Right to Buy) · Derivative 56,250 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020889 · tm226394-2_4seq1.xml · derivative · entry 1

Cramer Pamela J. · CIK 0001873517 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,250

Underlying: Common Stock · 56,250 shares

Expires 2032-02-08

F1 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 11, 2022 21:35 UTC
Roberts William T.Chief Accounting Officer
GrantRestricted Stock Units · Derivative 9,250 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020898 · tm226394-9_4seq1.xml · derivative · entry 2

Roberts William T. · CIK 0001852360 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,250

Underlying: Common Stock · 9,250 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
February 09, 2022 Filed Feb 11, 2022 21:35 UTC
Roberts William T.Chief Accounting Officer
GrantStock Option (Right to Buy) · Derivative 18,500 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020898 · tm226394-9_4seq1.xml · derivative · entry 1

Roberts William T. · CIK 0001852360 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,500

Underlying: Common Stock · 18,500 shares

Expires 2032-02-08

F1 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:31 UTC
Lee Jennifer KaydenEVP, Head of North America
GrantStock Option (Right to Buy) · Derivative 82,500 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020887 · tm226394-1_4seq1.xml · derivative · entry 2

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,500

Underlying: Common Stock · 82,500 shares

Expires 2032-02-08

F3 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:31 UTC
Lee Jennifer KaydenEVP, Head of North America
GrantRestricted Stock Units · Derivative 13,750 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020887 · tm226394-1_4seq1.xml · derivative · entry 1

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,750

Underlying: Common Stock · 13,750 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F2 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:33 UTC
Meeker David PDirector · President and CEO
GrantStock Option (Right to Buy) · Derivative 510,000 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020892 · tm226394-4_4seq1.xml · derivative · entry 1

Meeker David P · CIK 0001385155 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 510,000

Underlying: Common Stock · 510,000 shares

Expires 2032-02-08

F1 · derivative.exercise_date: The stock options were granted on February 9, 2022. The option vests and becomes exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:35 UTC
Smith Hunter CChief Financial Officer
GrantStock Option (Right to Buy) · Derivative 97,500 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020896 · tm226394-7_4seq1.xml · derivative · entry 2

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,500

Underlying: Common Stock · 97,500 shares

Expires 2032-02-08

F3 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:35 UTC
Smith Hunter CChief Financial Officer
GrantRestricted Stock Units · Derivative 16,250 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020896 · tm226394-7_4seq1.xml · derivative · entry 1

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,250

Underlying: Common Stock · 16,250 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F2 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:34 UTC
Shulman JosephChief Technical Officer
GrantStock Option (Right to Buy) · Derivative 63,750 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020895 · tm226394-6_4seq1.xml · derivative · entry 2

Shulman Joseph · CIK 0001909855 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,750

Underlying: Common Stock · 63,750 shares

Expires 2032-02-08

F3 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:34 UTC
Shulman JosephChief Technical Officer
GrantRestricted Stock Units · Derivative 10,625 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020895 · tm226394-6_4seq1.xml · derivative · entry 1

Shulman Joseph · CIK 0001909855 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,625

Underlying: Common Stock · 10,625 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F2 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:33 UTC
Mazabraud YannEVP, Head of International
GrantStock Option (Right to Buy) · Derivative 82,500 $0.00 Strike: $6.80 $0.00
Disclosure

SEC source: 0001104659-22-020890 · tm226394-3_4seq1.xml · derivative · entry 2

Mazabraud Yann · CIK 0001774702 · EVP, Head of International

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,500

Underlying: Common Stock · 82,500 shares

Expires 2032-02-08

F3 · derivative.exercise_date: The stock options were granted on February 9, 2022. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

Read SEC document
February 09, 2022 Filed Feb 12, 2022 02:33 UTC
Mazabraud YannEVP, Head of International
GrantRestricted Stock Units · Derivative 13,750 $0.00 $0.00
Disclosure

SEC source: 0001104659-22-020890 · tm226394-3_4seq1.xml · derivative · entry 1

Mazabraud Yann · CIK 0001774702 · EVP, Head of International

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,750

Underlying: Common Stock · 13,750 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

F2 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 9, 2023, February 9, 2024, February 9, 2025 and February 9, 2026. The restricted stock units have no expiration date.

Read SEC document
September 10, 2021 Filed Sep 15, 2021 18:51 UTC
Manning Linda ShapiroChief Medical Officer
GrantRestricted Stock Units · Derivative 2,500 $0.00 $0.00
Disclosure

SEC source: 0001104659-21-116017 · tm2127623-2_4seq1.xml · derivative · entry 2

Manning Linda Shapiro · CIK 0001883256 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,500

Underlying: Common Stock · 2,500 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of September 10, 2022, September 10, 2023, September 10, 2024 and September 10, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of September 10, 2022, September 10, 2023, September 10, 2024 and September 10, 2025. The restricted stock units have no expiration date.

Read SEC document
September 10, 2021 Filed Sep 15, 2021 18:51 UTC
Manning Linda ShapiroChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $12.98 $0.00
Disclosure

SEC source: 0001104659-21-116017 · tm2127623-2_4seq1.xml · derivative · entry 1

Manning Linda Shapiro · CIK 0001883256 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-09-09

F1 · derivative.exercise_date: The stock options were granted on September 10, 2021. 25% of the shares subject to the option will vest and become exercisable on September 10, 2022 and the remaining 75% of the shares subject to the option shall vest and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.

Read SEC document
July 26, 2021 Filed Jul 28, 2021 00:12 UTC
Cramer Pamela J.Chief Human Resources Officer
GrantRestricted Stock Units · Derivative 12,500 $0.00 $0.00
Disclosure

SEC source: 0001104659-21-096480 · tm2123454-2_4seq1.xml · derivative · entry 2

Cramer Pamela J. · CIK 0001873517 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of July 26, 2022, July 26, 2023, July 26, 2024 and July 26, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of July 26, 2022, July 26, 2023, July 26, 2024 and July 26, 2025. The restricted stock units have no expiration date.

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July 26, 2021 Filed Jul 28, 2021 00:12 UTC
Cramer Pamela J.Chief Human Resources Officer
GrantStock Option (Right to Buy) · Derivative 75,000 $0.00 Strike: $19.02 $0.00
Disclosure

SEC source: 0001104659-21-096480 · tm2123454-2_4seq1.xml · derivative · entry 1

Cramer Pamela J. · CIK 0001873517 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires 2031-07-25

F1 · derivative.exercise_date: The stock options were granted on July 26, 2021. 25% of the shares subject to the option will vest and become exercisable on July 26, 2022 and the remaining 75% of the shares subject to the option shall vest and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.

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June 09, 2021 Filed Jun 11, 2021 20:06 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001104659-21-080103 · tm2119501-3_4seq1.xml · derivative · entry 1

GOOD JENNIFER L · CIK 0001229245 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 11, 2021 20:06 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001104659-21-080107 · tm2119501-5_4seq1.xml · derivative · entry 1

MCGIRR DAVID W J · CIK 0001219023 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 11, 2021 20:05 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001104659-21-080099 · tm2119501-2_4seq1.xml · derivative · entry 1

Bedrosian Camille L · CIK 0001326969 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 11, 2021 21:39 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001209191-21-039958 · doc4.xml · derivative · entry 1

Mathers Edward T · CIK 0001328625 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 11, 2021 20:06 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001104659-21-080106 · tm2119501-4_4seq1.xml · derivative · entry 1

JEAN CHRISTOPHE · CIK 0001378435 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 11, 2021 20:06 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001104659-21-080098 · tm2119501-1_4seq1.xml · derivative · entry 1

Arbuckle Stuart A · CIK 0001557290 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 11, 2021 20:06 UTC GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001104659-21-080109 · tm2119501-6_4seq1.xml · derivative · entry 1

TETRAULT LYNN A. · CIK 0001645512 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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June 09, 2021 Filed Jun 16, 2021 20:16 UTC Amendment GrantStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $18.99 $0.00
Disclosure

SEC source: 0001209191-21-040902 · doc4a.xml · derivative · entry 1

Mathers Edward T · CIK 0001328625 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2031-06-08

F1 · derivative.exercise_date: The options fully vest upon the earlier of (i) June 9, 2022 or (ii) the date of the Issuer's next annual meeting of the stockholders.

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April 21, 2021 Filed Apr 23, 2021 10:08 UTC
Smith Hunter CChief Financial Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $6.88 $0.00
Disclosure

SEC source: 0001104659-21-054045 · tm2113817-1_4seq1.xml · derivative · entry 2

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 163,094

Underlying: Common Stock · 5,000 shares

Expires 2027-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock options were granted on August 9, 2017. 25% of the stock options vested and became exercisable on July 31, 2018. 75% of the stock options shall vest in 36 successive, equal monthly installments with the first such installment vesting and becoming exercisable on August 31, 2018.

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April 21, 2021 Filed Apr 23, 2021 10:08 UTC
Smith Hunter CChief Financial Officer
Exercise / conversionCommon Stock 5,000 $6.88 $34,400.00
Disclosure

SEC source: 0001104659-21-054045 · tm2113817-1_4seq1.xml · nonDerivative · entry 1

Smith Hunter C · CIK 0001636385 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,650

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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March 30, 2021 Filed Mar 31, 2021 20:08 UTC
Meeker David PDirector · President and CEO
PurchaseCommon Stock 10,000 $20.17 $201,713.00
Disclosure

SEC source: 0001104659-21-044745 · tm2111512-1_4seq1.xml · nonDerivative · entry 1

Meeker David P · CIK 0001385155 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,335

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $20.03 to $20.22, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 29, 2021 Filed Mar 30, 2021 16:49 UTC
Roberts William T.Chief Accounting Officer
GrantRestricted Stock Units · Derivative 10,000 $0.00 $0.00
Disclosure

SEC source: 0001104659-21-043951 · tm2111372-1_4seq1.xml · derivative · entry 2

Roberts William T. · CIK 0001852360 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Underlying: Common Stock · 10,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F3 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of March 29, 2022, March 29, 2023, March 29, 2024 and March 29, 2025. The restricted stock units have no expiration date.

F3 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of March 29, 2022, March 29, 2023, March 29, 2024 and March 29, 2025. The restricted stock units have no expiration date.

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March 29, 2021 Filed Mar 30, 2021 16:49 UTC
Roberts William T.Chief Accounting Officer
GrantStock Option (Right to Buy) · Derivative 20,000 $0.00 Strike: $20.25 $0.00
Disclosure

SEC source: 0001104659-21-043951 · tm2111372-1_4seq1.xml · derivative · entry 1

Roberts William T. · CIK 0001852360 · Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2031-03-28

F1 · derivative.exercise_date: The stock options were granted on March 29, 2021. 25% of the shares subject to the option will vest and become exercisable on March 29, 2022 and the remaining 75% of the shares subject to the option shall vest and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.

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March 15, 2021 Filed Mar 16, 2021 21:13 UTC
Foley ToddDirector
SaleCommon Stock 1,000,000 $25.10 $25,100,000.00
Disclosure

SEC source: 0001209191-21-020931 · doc4.xml · nonDerivative · entry 1

Foley Todd · CIK 0001473930 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 909,258

F1 · shares: The shares were sold as follows: 962,604 by MPM BioVentures V, L.P. ("BV V") and 37,396 by MPM Asset Management Investors BV5 LLC ("AM BV5"). MPM BioVentures V GP LLC and MPM BioVentures V LLC ("BV LLC") are the direct and indirect general partners of BV V and BV LLC is the manager of AM BV5. The Reporting Person is a member of BV LLC. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

F2 · ownership.nature: Shares are held as follows: 875,256 by BV V and 34,002 by AM BV5. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

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February 11, 2021 Filed Feb 16, 2021 22:29 UTC
Lee Jennifer KaydenEVP, Head of North America
GrantStock Option (Right to Buy) · Derivative 48,750 $0.00 Strike: $30.66 $0.00
Disclosure

SEC source: 0001104659-21-024421 · tm216849-6_4seq1.xml · derivative · entry 2

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 48,750

Underlying: Common Stock · 48,750 shares

Expires 2031-02-10

F3 · derivative.exercise_date: The stock options were granted on February 11, 2021. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

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February 11, 2021 Filed Feb 16, 2021 22:29 UTC
Lee Jennifer KaydenEVP, Head of North America
GrantRestricted Stock Units · Derivative 8,125 $0.00 $0.00
Disclosure

SEC source: 0001104659-21-024421 · tm216849-6_4seq1.xml · derivative · entry 1

Chien Jennifer · CIK 0001801372 · EVP, Head of North America

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,125

Underlying: Common Stock · 8,125 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.

F2 · derivative.exercise_date: The restricted stock units vest as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date

F2 · derivative.expiration_date: The restricted stock units vest as to 25% of the total shares on each of February 11, 2022, February 11, 2023, February 11, 2024 and February 11, 2025. The restricted stock units have no expiration date

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February 11, 2021 Filed Feb 16, 2021 22:26 UTC
Meeker David PDirector · President and CEO
GrantStock Option (right to buy) · Derivative 220,000 $0.00 Strike: $30.66 $0.00
Disclosure

SEC source: 0001104659-21-024406 · tm216849-1_4seq1.xml · derivative · entry 1

Meeker David P · CIK 0001385155 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 220,000

Underlying: Common Stock · 220,000 shares

Expires 2031-02-10

F1 · derivative.exercise_date: The stock options were granted on February 11, 2021. The option vests and becomes exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.