RLMD

SEC source: 0001213900-23-007438 · ownership.xml · derivative · entry 1

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41

Underlying: Common Stock · 4,800 shares

Expires 2025-11-12

F1 · kind: Represents a bona fide gift of stock options to family members and a family trust. An independent trustee is trustee of the trust.

F2 · derivative.exercise_date: The options were granted on November 12, 2015. 25% of the options vested one year from the grant date and the remaining 75% of the options vested in equal quarterly increments of 6.25% of the initial option grant over the following three year period.

SEC source: 0001213900-23-007440 · ownership.xml · derivative · entry 6

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 162,500

Underlying: Common Stock · 87,500 shares

Expires 2031-01-07

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F7 · derivative.exercise_date: The options were granted on January 7, 2021. 25% of the options vested one year from the grant date, and thereafter in equal quarterly increments of 6.25% over the following three years.

SEC source: 0001213900-23-007440 · ownership.xml · derivative · entry 5

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 162,500

Underlying: Common Stock · 93,750 shares

Expires 2031-01-07

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F6 · derivative.exercise_date: The options were granted on January 7, 2021. 6.25% of the options vest each quarter from the date of grant.

SEC source: 0001213900-23-007440 · ownership.xml · derivative · entry 4

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 218,750

Underlying: Common Stock · 131,250 shares

Expires 2029-12-19

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F5 · derivative.exercise_date: The options were granted on December 19, 2019. 6.25% of the options vest each quarter from the date of grant.

SEC source: 0001213900-23-007440 · ownership.xml · derivative · entry 3

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,019

Underlying: Common Stock · 8,231 shares

Expires 2025-02-23

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F4 · derivative.exercise_date: The options were granted on February 15, 2015. 6.25% of the options vested each quarter from the date of grant.

SEC source: 0001213900-23-007440 · ownership.xml · derivative · entry 2

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,165

Underlying: Common Stock · 27,123 shares

Expires 2023-09-30

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F3 · derivative.exercise_date: The options were granted on September 30, 2013. 25% of the options vested upon the date of grant and the remaining 75% of the options vested in equal quarterly increments over the next four (4) years, so that the last set of options vested in September 2017.

SEC source: 0001213900-23-007440 · ownership.xml · derivative · entry 1

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,131 shares

Expires 2022-07-10

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F2 · derivative.exercise_date: The options were granted on July 10, 2012. 25% of the options vested upon the grant date and the remaining 75% of the options vested in equal quarterly increments over the next four (4) years, so that the last set of options vested in July 2016.

SEC source: 0001213900-23-008514 · ownership.xml · derivative · entry 5

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 225,000

Underlying: Common Stock · 31,250 shares

Expires 2031-01-07

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F6 · derivative.exercise_date: The options were granted on January 7, 2021. 6.25% of the options vest each quarter from the date of grant.

SEC source: 0001213900-23-008514 · ownership.xml · derivative · entry 4

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 218,750

Underlying: Common Stock · 131,250 shares

Expires 2029-12-19

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F5 · derivative.exercise_date: The options were granted on December 19, 2019. 6.25% of the options vest each quarter from the date of grant.

SEC source: 0001213900-23-008514 · ownership.xml · derivative · entry 3

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,019

Underlying: Common Stock · 8,231 shares

Expires 2025-02-23

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F4 · derivative.exercise_date: The options were granted on February 15, 2015. 6.25% of the options vested each quarter from the date of grant.

SEC source: 0001213900-23-008514 · ownership.xml · derivative · entry 2

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,165

Underlying: Common Stock · 27,123 shares

Expires 2023-09-30

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F3 · derivative.exercise_date: The options were granted on September 30, 2013. 25% of the options vested upon the date of grant and the remaining 75% of the options vested in equal quarterly increments over the next four (4) years, so that the last set of options vested in September 2017.

SEC source: 0001213900-23-008514 · ownership.xml · derivative · entry 1

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,131 shares

Expires 2022-07-10

F1 · kind: Represents a bona fide gift of stock options to a family trust. An independent trustee is trustee of the trust.

F2 · derivative.exercise_date: The options were granted on July 10, 2012. 25% of the options vested upon the grant date and the remaining 75% of the options vested in equal quarterly increments over the next four (4) years, so that the last set of options vested in July 2016.

SEC source: 0001213900-21-030571 · ownership.xml · nonDerivative · entry 2

CASAMENTO CHARLES J · CIK 0001117167 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,950

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 29, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $32.85 to $33.42 per share, inclusive.

SEC source: 0001213900-21-030571 · ownership.xml · nonDerivative · entry 1

CASAMENTO CHARLES J · CIK 0001117167 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,430

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 29, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $33.84 to $34.54 per share, inclusive.

SEC source: 0001213900-21-024716 · ownership.xml · nonDerivative · entry 1

CASAMENTO CHARLES J · CIK 0001117167 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,950

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 29, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $37.94 to $38.94 per share, inclusive.

SEC source: 0001213900-21-020123 · ownership.xml · nonDerivative · entry 2

CASAMENTO CHARLES J · CIK 0001117167 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,950

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 29, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $34.69 to $35.49 per share, inclusive.

SEC source: 0001213900-21-020123 · ownership.xml · nonDerivative · entry 1

CASAMENTO CHARLES J · CIK 0001117167 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,641

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 29, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $35.80 to $36.12 per share, inclusive.

SEC source: 0001213900-21-014656 · ownership.xml · nonDerivative · entry 5

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,228

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F5 · price: Sales prices range from $35.00 to $35.37 per share, inclusive.

SEC source: 0001213900-21-014918 · ownership.xml · nonDerivative · entry 4

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,774

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F5 · price: Sales prices range from $35.00 to $35.37 per share, inclusive.

SEC source: 0001213900-21-014656 · ownership.xml · nonDerivative · entry 4

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,601

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $36.02 to $36.51 per share, inclusive.

SEC source: 0001213900-21-014656 · ownership.xml · nonDerivative · entry 3

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,401

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $35.02 to $35.95 per share, inclusive.

SEC source: 0001213900-21-014917 · ownership.xml · derivative · entry 4

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,500

Underlying: Common Stock · 5,000 shares

Expires 2027-10-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · price: Not applicable.

F5 · derivative.exercise_date: The options vest from the date of grant in equal quarterly increments of 6.25% over a four year period.

SEC source: 0001213900-21-014917 · ownership.xml · nonDerivative · entry 3

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,295

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $36.07 to $36.55 per share, inclusive.

SEC source: 0001213900-21-014917 · ownership.xml · nonDerivative · entry 2

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 168,907

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $35.00 to $35.94 per share, inclusive.

SEC source: 0001213900-21-014917 · ownership.xml · nonDerivative · entry 1

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,295

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-014918 · ownership.xml · derivative · entry 5

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,211

Underlying: Common Stock · 10,000 shares

Expires 2027-10-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: Not applicable.

F6 · derivative.exercise_date: The options vest from the date of grant in equal quarterly increments of 6.25% over a four year period.

SEC source: 0001213900-21-014918 · ownership.xml · nonDerivative · entry 3

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 91,757

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $36.02 to $36.65 per share, inclusive.

SEC source: 0001213900-21-014918 · ownership.xml · nonDerivative · entry 2

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,937

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $35.00 to $35.94 per share, inclusive.

SEC source: 0001213900-21-014918 · ownership.xml · nonDerivative · entry 1

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,774

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-014656 · ownership.xml · derivative · entry 6

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,350

Underlying: Common Stock · 10,000 shares

Expires 2027-10-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: Not applicable

F6 · derivative.exercise_date: The options vest from the date of grant in equal quarterly increments of 6.25% over a four year period.

SEC source: 0001213900-21-014656 · ownership.xml · nonDerivative · entry 2

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,128

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

SEC source: 0001213900-21-014656 · ownership.xml · nonDerivative · entry 1

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,228

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-012891 · ownership.xml · nonDerivative · entry 1

CASAMENTO CHARLES J · CIK 0001117167 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,950

F1 · kind: The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 29, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $33.56 to $34.28 per share, inclusive.

SEC source: 0001213900-21-012171 · ownership.xml · nonDerivative · entry 4

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,295

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F5 · price: Sales prices range from $35.49 to $35.59 per share, inclusive.

SEC source: 0001213900-21-012171 · ownership.xml · nonDerivative · entry 3

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,403

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $34.29 to $35.15 per share, inclusive.

SEC source: 0001213900-21-012171 · ownership.xml · nonDerivative · entry 2

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 169,866

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $33.29 to $34.28 per share, inclusive.

SEC source: 0001213900-21-012171 · ownership.xml · nonDerivative · entry 1

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 172,295

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-012169 · ownership.xml · derivative · entry 4

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,250

Underlying: Common Stock · 3,000 shares

Expires 2027-10-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · price: Not applicable

F5 · derivative.exercise_date: The options vest from the date of grant in equal quarterly increments of 6.25% over a four year period.

SEC source: 0001213900-21-012169 · ownership.xml · nonDerivative · entry 3

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,228

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $34.47 to $35.03 per share, inclusive.

SEC source: 0001213900-21-012169 · ownership.xml · nonDerivative · entry 2

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,628

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $33.35 to $34.30 per share, inclusive.

SEC source: 0001213900-21-012169 · ownership.xml · nonDerivative · entry 1

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,228

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-012174 · ownership.xml · derivative · entry 5

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,211

Underlying: Common Stock · 10,000 shares

Expires 2027-10-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: Not applicable.

F6 · derivative.exercise_date: The options vest from the date of grant in equal quarterly increments of 6.25% over a four year period.

SEC source: 0001213900-21-012174 · ownership.xml · nonDerivative · entry 4

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 88,774

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F5 · price: Sales prices range from $35.45 to $35.65 per share, inclusive.

SEC source: 0001213900-21-012174 · ownership.xml · nonDerivative · entry 3

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 89,077

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F4 · price: Sales prices range from $34.41 to $35.33 per share, inclusive.

SEC source: 0001213900-21-012174 · ownership.xml · nonDerivative · entry 2

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,937

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b51 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $33.34 to $34.28 per share, inclusive.

SEC source: 0001213900-21-012174 · ownership.xml · nonDerivative · entry 1

TRAVERSA SERGIO · CIK 0001565832 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,774

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-010148 · ownership.xml · derivative · entry 2

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 5,000 shares

Expires 2024-10-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: This Warrant was previously reported as covering 100,000 shares of common stock at an exercise price of $1.50 per share, but was adjusted to reflect the stock split that occurred on September 30, 2019.

F1 · balance_after: This Warrant was previously reported as covering 100,000 shares of common stock at an exercise price of $1.50 per share, but was adjusted to reflect the stock split that occurred on September 30, 2019.

SEC source: 0001213900-21-010148 · ownership.xml · nonDerivative · entry 1

Kelly Paul Edward · CIK 0001658544 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,295

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001213900-21-009696 · ownership.xml · derivative · entry 3

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 83,250

Underlying: Common Stock · 1,428 shares

Expires 2027-10-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · price: Not applicable

F4 · derivative.exercise_date: The options vest from the date of grant in equal quarterly increments of 6.25% over a four year period.

SEC source: 0001213900-21-009696 · ownership.xml · nonDerivative · entry 2

Shenouda Maged · CIK 0001658369 · CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,228

F1 · kind: The sales reported on this Form 4 were effectuated pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 22, 2020.

F2 · shares: The number of securities reported represents an aggregate number of shares sold in multiple open market transactions over a range of sales prices. The price reported represents the weighted average price. The Reporting Person undertakes to provide to the staff of the SEC, the Issuer, or a stockholder of the Issuer, upon request, the number of shares sold by the Reporting Person at each separate price within the range.

F3 · price: Sales prices range from $35.12 to $35.96 per share, inclusive.