QURE

SEC source: 0000904454-22-000633 · edgar.xml · derivative · entry 5

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,000

Underlying: Ordinary Shares · 3,000 shares

Expires 2027-01-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000633 · edgar.xml · nonDerivative · entry 2

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,382

F1 · kind: The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000633 · edgar.xml · nonDerivative · entry 1

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,382

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000611 · edgar.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 368,481

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $22.39 to $22.60. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000619 · edgar.xml · nonDerivative · entry 1

Dolmetsch Ricardo · CIK 0001825206 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 127,406

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $22.23 to $22.60. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000617 · edgar.xml · nonDerivative · entry 1

CALOZ PIERRE · CIK 0001867944 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 68,870

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $22.15 to $22.60. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000615 · edgar.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,180

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $22.29 to $22.60. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000613 · edgar.xml · nonDerivative · entry 1

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,652

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of performance-based restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $22.33 to $22.60. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000601 · edgar.xml · derivative · entry 3

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,800

Underlying: Ordinary Shares · 6,200 shares

Expires 2023-06-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: The Stock Option exercise price was EUR 10.10 per share or $10.46, as converted, based on the exchange rate at exercise of EUR 1 to $1.036.

F1 · kind: The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · derivative.exercise_date: The Stock Option was granted on June 6, 2013 and vested 25% after one year, with the remainder vesting in weekly installments over a two year period ending on June 10, 2016.

SEC source: 0000904454-22-000601 · edgar.xml · nonDerivative · entry 2

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,382

F1 · kind: The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F4 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $25.33 to $25.48. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000601 · edgar.xml · nonDerivative · entry 1

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,582

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · price: The Stock Option exercise price was EUR 10.10 per share or $10.46, as converted, based on the exchange rate at exercise of EUR 1 to $1.036.

SEC source: 0000899243-22-037030 · doc4.xml · nonDerivative · entry 1

CALOZ PIERRE · CIK 0001867944 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,811

F1 · shares: Represents performance-based restricted share units ("PRSUs") granted to the Reporting Person on December 8, 2021 under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on November 22, 2022 as the result of the satisfaction of certain performance criteria. Each PRSU represents the contingent right to receive one Ordinary Share.

SEC source: 0000899243-22-037024 · doc4.xml · nonDerivative · entry 1

Dolmetsch Ricardo · CIK 0001825206 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 129,625

F1 · shares: Represents performance-based restricted share units ("PRSUs") granted to the Reporting Person on December 8, 2021 under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on November 22, 2022 as the result of the satisfaction of certain performance criteria. Each PRSU represents the contingent right to receive one Ordinary Share.

SEC source: 0000899243-22-037025 · doc4.xml · nonDerivative · entry 1

Kapusta Matthew C · CIK 0001536290 · Director · CEO, Managing Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 375,129

F1 · shares: Represents performance-based restricted share units ("PRSUs") granted to the Reporting Person on December 8, 2021 under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on November 22, 2022 as the result of the satisfaction of certain performance criteria. Each PRSU represents the contingent right to receive one Ordinary Share.

SEC source: 0000899243-22-037027 · doc4.xml · nonDerivative · entry 1

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,990

F1 · shares: Represents performance-based restricted share units ("PRSUs") granted to the Reporting Person on December 8, 2021 under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on November 22, 2022 as the result of the satisfaction of certain performance criteria. Each PRSU represents the contingent right to receive one Ordinary Share.

SEC source: 0000899243-22-037026 · doc4.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,788

F1 · shares: Represents performance-based restricted share units ("PRSUs") granted to the Reporting Person on December 8, 2021 under the Issuer's 2014 Share Incentive Plan, as amended and restated, which vested on November 22, 2022 as the result of the satisfaction of certain performance criteria. Each PRSU represents the contingent right to receive one Ordinary Share.

SEC source: 0000904454-22-000474 · edgar.xml · nonDerivative · entry 1

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 92,890

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

SEC source: 0000904454-22-000400 · edgar.xml · derivative · entry 7

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Ordinary Shares · 27,358 shares

Expires 2027-01-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · derivative.exercise_date: The Stock Option vested 25% on January 23, 2018 (the first anniversary of the date of grant), and vests 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-22-000400 · edgar.xml · nonDerivative · entry 5

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,196

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000400 · edgar.xml · nonDerivative · entry 4

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,602

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000400 · edgar.xml · nonDerivative · entry 3

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 122,554

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000400 · edgar.xml · derivative · entry 6

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,358

Underlying: Ordinary Shares · 10,404 shares

Expires 2027-01-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · derivative.exercise_date: The Stock Option vested 25% on January 23, 2018 (the first anniversary of the date of grant), and vests 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-22-000400 · edgar.xml · nonDerivative · entry 2

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,196

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000400 · edgar.xml · nonDerivative · entry 1

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,600

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000398 · edgar.xml · derivative · entry 6

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,762

Underlying: Ordinary Shares · 5,643 shares

Expires 2027-01-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · derivative.exercise_date: The Stock Option vested 25% on January 23, 2018 (the first anniversary of the date of grant), and vests 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-22-000398 · edgar.xml · nonDerivative · entry 4

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,196

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000398 · edgar.xml · nonDerivative · entry 3

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,839

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000398 · edgar.xml · derivative · entry 5

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,405

Underlying: Ordinary Shares · 595 shares

Expires 2027-01-23

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F2 · derivative.exercise_date: The Stock Option vested 25% on January 23, 2018 (the first anniversary of the date of grant), and vests 6.25% quarterly thereafter until fully vested, subject to the Reporting Person's continued relationship with the Issuer through such dates.

SEC source: 0000904454-22-000398 · edgar.xml · nonDerivative · entry 2

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,196

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

SEC source: 0000904454-22-000398 · edgar.xml · nonDerivative · entry 1

Kuta Alexander Edward III · CIK 0001696698 · Executive VP, Operations

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,791

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transactions reported herein were effected pursuant to a sales plan dated March 3, 2021 adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934.

F3 · balance_after: Adjusted to correct a typographical error on the Reporting Person's last Form 4, pursuant to which the number of Ordinary Shares held after the reported transaction was inadvertently under-reported by 40 shares.

SEC source: 0000904454-22-000368 · edgar.xml · nonDerivative · entry 1

CALOZ PIERRE · CIK 0001867944 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,511

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $13.06 to $13.26. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000366 · edgar.xml · nonDerivative · entry 1

KLEMT CHRISTIAN · CIK 0001711885 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,688

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $13.01 to $13.23. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000356 · edgar.xml · derivative · entry 2

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000356 · edgar.xml · nonDerivative · entry 1

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,382

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000362 · edgar.xml · derivative · entry 2

POST LEONARD E · CIK 0001235862 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000362 · edgar.xml · nonDerivative · entry 1

POST LEONARD E · CIK 0001235862 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,201

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000360 · edgar.xml · derivative · entry 2

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000360 · edgar.xml · nonDerivative · entry 1

Kaye Jack · CIK 0001376099 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,083

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000352 · edgar.xml · derivative · entry 2

Meek David D. · CIK 0001555337 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000352 · edgar.xml · nonDerivative · entry 1

Meek David D. · CIK 0001555337 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,460

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000354 · edgar.xml · derivative · entry 2

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000354 · edgar.xml · nonDerivative · entry 1

Balachandran Madhavan · CIK 0001555508 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,957

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000364 · edgar.xml · derivative · entry 2

Jacques Rachelle Suzanne · CIK 0001772610 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000364 · edgar.xml · nonDerivative · entry 1

Jacques Rachelle Suzanne · CIK 0001772610 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,614

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000358 · edgar.xml · derivative · entry 2

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000358 · edgar.xml · nonDerivative · entry 1

Gut Robert · CIK 0001716268 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,165

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000350 · edgar.xml · derivative · entry 2

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,810

Underlying: Ordinary Shares · 17,810 shares

Expires 2032-06-15

F2 · derivative.exercise_date: The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000350 · edgar.xml · nonDerivative · entry 1

Springhorn Jeremy P. · CIK 0001717852 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,957

F1 · shares: Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date.

SEC source: 0000904454-22-000211 · edgar.xml · nonDerivative · entry 1

Soteropoulos Paula · CIK 0001692444 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,302

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $16.82 to $16.88. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000904454-22-000221 · edgar.xml · nonDerivative · entry 1

POST LEONARD E · CIK 0001235862 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,121

F1 · kind: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F1 · shares: As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $16.64 to $16.80. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.