Last 12 months
Inside the activity.
4 purchase rows · 11 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 0 |
| Dec 2025 | 0 | 2 |
| Jan 2026 | 0 | 0 |
| Feb 2026 | 0 | 3 |
| Mar 2026 | 0 | 0 |
| Apr 2026 | 0 | 0 |
| May 2026 | 4 | 0 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 0 |
| Aug 2026 | 0 | 3 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 3 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| December 24, 2019 Filed Dec 28, 2019 00:09 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 151,233 | $21.95 | $3,319,579.47 |
DisclosureSEC source: 0001193805-19-001981 · e619266_4-homology.xml · nonDerivative · entry 2 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Healthcare Innovations Fund, L.P. Disclosed balance after: 1,766,106 F1 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.95 to $22.01, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 24, 2019 Filed Dec 28, 2019 00:09 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 198,767 | $21.95 | $4,362,955.53 |
DisclosureSEC source: 0001193805-19-001981 · e619266_4-homology.xml · nonDerivative · entry 1 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Private Design Fund III, L.P. Disclosed balance after: 2,321,199 F1 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.95 to $22.01, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 23, 2019 Filed Dec 24, 2019 00:57 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 56,595 | $21.83 | $1,235,434.89 |
DisclosureSEC source: 0001193805-19-001976 · e619262_4-homology.xml · nonDerivative · entry 6 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Healthcare Innovations Fund, L.P. Disclosed balance after: 1,917,339 F5 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.50 to $22.30, inclusive. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 23, 2019 Filed Dec 24, 2019 00:57 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 74,384 | $21.83 | $1,623,758.09 |
DisclosureSEC source: 0001193805-19-001976 · e619262_4-homology.xml · nonDerivative · entry 5 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Private Design Fund III, L.P. Disclosed balance after: 2,519,966 F5 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.50 to $22.30, inclusive. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 20, 2019 Filed Dec 24, 2019 00:57 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 9,130 | $21.50 | $196,296.83 |
DisclosureSEC source: 0001193805-19-001976 · e619262_4-homology.xml · nonDerivative · entry 4 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Healthcare Innovations Fund, L.P. Disclosed balance after: 1,973,934 F4 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.50 to $21.54, inclusive. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 20, 2019 Filed Dec 24, 2019 00:57 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 11,999 | $21.50 | $257,980.90 |
DisclosureSEC source: 0001193805-19-001976 · e619262_4-homology.xml · nonDerivative · entry 3 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Private Design Fund III, L.P. Disclosed balance after: 2,594,350 F4 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.50 to $21.54, inclusive. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 19, 2019 Filed Dec 24, 2019 00:57 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 5,454 | $21.68 | $118,218.72 |
DisclosureSEC source: 0001193805-19-001976 · e619262_4-homology.xml · nonDerivative · entry 2 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Healthcare Innovations Fund, L.P. Disclosed balance after: 1,983,064 F1 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.55 to $21.94, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1), (4) and (5) of this Form 4. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 19, 2019 Filed Dec 24, 2019 00:57 UTC |
Flynn James E10% owner · Possible Member of 10% Group
DEERFIELD MANAGEMENT COMPANY, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt L.P.10% owner · Possible Member of 10% Group
DEERFIELD PARTNERS, L.P.10% owner · Possible Member of 10% Group
Deerfield Private Design Fund III, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt III, L.P.10% owner · Possible Member of 10% Group
Deerfield Healthcare Innovations Fund, L.P.10% owner · Possible Member of 10% Group
Deerfield Mgmt HIF, L.P.10% owner · Possible Member of 10% Group
|
SaleCommon Stock | 7,168 | $21.68 | $155,370.70 |
DisclosureSEC source: 0001193805-19-001976 · e619262_4-homology.xml · nonDerivative · entry 1 Flynn James E · CIK 0001352546 · 10% owner · Possible Member of 10% Group DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) · CIK 0001009258 · 10% owner · Possible Member of 10% Group Deerfield Mgmt L.P. · CIK 0001010823 · 10% owner · Possible Member of 10% Group DEERFIELD PARTNERS, L.P. · CIK 0001301041 · 10% owner · Possible Member of 10% Group Deerfield Private Design Fund III, L.P. · CIK 0001603333 · 10% owner · Possible Member of 10% Group Deerfield Mgmt III, L.P. · CIK 0001610540 · 10% owner · Possible Member of 10% Group Deerfield Healthcare Innovations Fund, L.P. · CIK 0001646981 · 10% owner · Possible Member of 10% Group Deerfield Mgmt HIF, L.P. · CIK 0001665736 · 10% owner · Possible Member of 10% Group Joint disclosure: these amounts are not allocated separately to each reporting owner. 10b5-1 filing: Not disclosed Ownership: Indirect · Through Deerfield Private Design Fund III, L.P. Disclosed balance after: 2,606,349 F1 · price: The price reported in Column 4 represents a weighted average price. The shares were sold in multiple transactions at prices ranging from $21.55 to $21.94, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1), (4) and (5) of this Form 4. F2 · ownership.nature: This Form 4 is being filed by the undersigned as well as the entities listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt III, L.P. is the general partner of Deerfield Private Design Fund III, L.P. ("Fund III"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Fund III and Deerfield Partners, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. F3 · ownership.nature: In accordance with Instruction 4 (b)(iv) to Form 4, the entire amount of the Issuer's securities held by the Funds is reported herein. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Read SEC document |
| December 11, 2019 Filed Dec 13, 2019 21:05 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
GrantEmployee Stock Option (Right to Buy) · Derivative | 111,000 | $0.00 Strike: $19.92 | $0.00 |
DisclosureSEC source: 0000899243-19-029153 · doc4.xml · derivative · entry 1 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 111,000 Underlying: Common Stock · 111,000 shares Expires 2029-12-11 F1 · derivative.exercise_date: The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2020. Read SEC document |
| December 11, 2019 Filed Dec 13, 2019 21:07 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
GrantEmployee Stock Option (Right to Buy) · Derivative | 358,000 | $0.00 Strike: $19.92 | $0.00 |
DisclosureSEC source: 0000899243-19-029158 · doc4.xml · derivative · entry 1 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 358,000 Underlying: Common Stock · 358,000 shares Expires 2029-12-11 F1 · derivative.exercise_date: The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2020. Read SEC document |
| December 11, 2019 Filed Dec 13, 2019 21:07 UTC |
Cohn GabrielChief Medical Officer
|
GrantEmployee Stock Option (Right to Buy) · Derivative | 15,000 | $0.00 Strike: $19.92 | $0.00 |
DisclosureSEC source: 0000899243-19-029157 · doc4.xml · derivative · entry 1 Cohn Gabriel · CIK 0001794702 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,000 Underlying: Common Stock · 15,000 shares Expires 2029-12-11 F1 · derivative.exercise_date: The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2020. Read SEC document |
| December 11, 2019 Filed Dec 13, 2019 21:06 UTC |
Seymour AlbertChief Scientific Officer
|
GrantEmployee Stock Option (Right to Buy) · Derivative | 110,000 | $0.00 Strike: $19.92 | $0.00 |
DisclosureSEC source: 0000899243-19-029156 · doc4.xml · derivative · entry 1 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 110,000 Underlying: Common Stock · 110,000 shares Expires 2029-12-11 F1 · derivative.exercise_date: The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2020. Read SEC document |
| December 11, 2019 Filed Dec 13, 2019 21:05 UTC |
Kelly Timothy PSee Remarks
|
GrantEmployee Stock Option (Right to Buy) · Derivative | 112,000 | $0.00 Strike: $19.92 | $0.00 |
DisclosureSEC source: 0000899243-19-029154 · doc4.xml · derivative · entry 1 Kelly Timothy P · CIK 0001754067 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 112,000 Underlying: Common Stock · 112,000 shares Expires 2029-12-11 F1 · derivative.exercise_date: The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2020. Read SEC document |
| December 02, 2019 Filed Dec 3, 2019 21:07 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionEmployee Stock Option · Derivative | 6,000 | $0.00 Strike: $0.64 | $0.00 |
DisclosureSEC source: 0000899243-19-028395 · doc4.xml · derivative · entry 6 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 121,404 Underlying: Common Stock · 6,000 shares Expires 2027-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was April 3, 2017. Read SEC document |
| December 02, 2019 Filed Dec 3, 2019 21:07 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 6,000 | $16.21 | $97,266.00 |
DisclosureSEC source: 0000899243-19-028395 · doc4.xml · nonDerivative · entry 4 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.03 to $16.35. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| December 02, 2019 Filed Dec 3, 2019 21:07 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionCommon Stock | 6,000 | $0.64 | $3,840.00 |
DisclosureSEC source: 0000899243-19-028395 · doc4.xml · nonDerivative · entry 3 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| December 02, 2019 Filed Dec 3, 2019 21:06 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
SaleCommon Stock | 12,500 | $16.25 | $203,176.25 |
DisclosureSEC source: 0000899243-19-028394 · doc4.xml · nonDerivative · entry 2 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 102,505 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F3 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.02 to $16.39. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| December 02, 2019 Filed Dec 3, 2019 21:09 UTC |
Cohn GabrielChief Medical Officer
|
GrantEmployee Stock Option (Right to Buy) · Derivative | 120,000 | $0.00 Strike: $17.14 | $0.00 |
DisclosureSEC source: 0000899243-19-028397 · doc4.xml · derivative · entry 1 Cohn Gabriel · CIK 0001794702 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 120,000 Underlying: Common Stock · 120,000 shares Expires 2029-12-02 F1 · derivative.exercise_date: The option vests and becomes exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was December 2, 2019. Read SEC document |
| December 02, 2019 Filed Dec 3, 2019 21:05 UTC |
Seymour AlbertChief Scientific Officer
|
SaleCommon Stock | 9,300 | $16.23 | $150,969.69 |
DisclosureSEC source: 0000899243-19-028392 · doc4.xml · nonDerivative · entry 2 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 163,150 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F3 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.04 to $16.355. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| November 29, 2019 Filed Dec 3, 2019 21:07 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionEmployee Stock Option · Derivative | 6,000 | $0.00 Strike: $0.64 | $0.00 |
DisclosureSEC source: 0000899243-19-028395 · doc4.xml · derivative · entry 5 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 127,404 Underlying: Common Stock · 6,000 shares Expires 2027-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was April 3, 2017. Read SEC document |
| November 29, 2019 Filed Dec 3, 2019 21:07 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 6,000 | $16.00 | $96,000.00 |
DisclosureSEC source: 0000899243-19-028395 · doc4.xml · nonDerivative · entry 2 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. Read SEC document |
| November 29, 2019 Filed Dec 3, 2019 21:07 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionCommon Stock | 6,000 | $0.64 | $3,840.00 |
DisclosureSEC source: 0000899243-19-028395 · doc4.xml · nonDerivative · entry 1 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| November 29, 2019 Filed Dec 3, 2019 21:06 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
SaleCommon Stock | 12,500 | $16.04 | $200,558.75 |
DisclosureSEC source: 0000899243-19-028394 · doc4.xml · nonDerivative · entry 1 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 115,005 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.00 to $16.1550. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| November 29, 2019 Filed Dec 3, 2019 21:05 UTC |
Seymour AlbertChief Scientific Officer
|
SaleCommon Stock | 9,300 | $16.06 | $149,389.62 |
DisclosureSEC source: 0000899243-19-028392 · doc4.xml · nonDerivative · entry 1 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 172,450 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.00 to $16.24. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| November 18, 2019 Filed Jan 29, 2020 18:43 UTC |
Gregory Richard J.Director
|
Exercise / conversionEmployee Stock Option · Derivative | 10,806 | $0.00 Strike: $0.03 | $0.00 |
DisclosureSEC source: 0000899243-20-002311 · doc4.xml · derivative · entry 2 Gregory Richard J. · CIK 0001629767 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 10,806 shares Expires 2025-05-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: This option is fully vested. Read SEC document |
| November 18, 2019 Filed Jan 29, 2020 18:43 UTC |
Gregory Richard J.Director
|
Exercise / conversionCOMMON STOCK | 10,806 | $0.03 | $324.18 |
DisclosureSEC source: 0000899243-20-002311 · doc4.xml · nonDerivative · entry 1 Gregory Richard J. · CIK 0001629767 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,806 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:08 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionEmployee Stock Option · Derivative | 6,000 | $0.00 Strike: $0.64 | $0.00 |
DisclosureSEC source: 0000899243-19-024658 · doc4.xml · derivative · entry 4 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 133,404 Underlying: Common Stock · 6,000 shares Expires 2027-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was April 3, 2017. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:08 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 100 | $18.23 | $1,823.00 |
DisclosureSEC source: 0000899243-19-024658 · doc4.xml · nonDerivative · entry 3 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:08 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 5,900 | $17.38 | $102,543.77 |
DisclosureSEC source: 0000899243-19-024658 · doc4.xml · nonDerivative · entry 2 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $17.10 to $17.85. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:08 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionCommon Stock | 6,000 | $0.64 | $3,840.00 |
DisclosureSEC source: 0000899243-19-024658 · doc4.xml · nonDerivative · entry 1 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:08 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
SaleCommon Stock | 100 | $18.23 | $1,823.00 |
DisclosureSEC source: 0000899243-19-024657 · doc4.xml · nonDerivative · entry 2 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 127,505 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:08 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
SaleCommon Stock | 12,400 | $17.39 | $215,644.68 |
DisclosureSEC source: 0000899243-19-024657 · doc4.xml · nonDerivative · entry 1 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 127,605 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $17.07 to $18.02. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:07 UTC |
Seymour AlbertChief Scientific Officer
|
SaleCommon Stock | 100 | $18.23 | $1,823.00 |
DisclosureSEC source: 0000899243-19-024656 · doc4.xml · nonDerivative · entry 2 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 181,750 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. Read SEC document |
| October 01, 2019 Filed Oct 2, 2019 20:07 UTC |
Seymour AlbertChief Scientific Officer
|
SaleCommon Stock | 9,200 | $17.38 | $159,936.48 |
DisclosureSEC source: 0000899243-19-024656 · doc4.xml · nonDerivative · entry 1 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 181,850 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $17.09 to $17.85. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| September 05, 2019 Filed Sep 9, 2019 20:05 UTC |
Kelly Timothy PSee Remarks
|
SaleCommon Stock | 1,166 | $19.94 | $23,251.44 |
DisclosureSEC source: 0000899243-19-023114 · doc4.xml · nonDerivative · entry 1 Kelly Timothy P · CIK 0001754067 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · shares: Consists of 1,166 shares acquired under the Issuer's Employee Stock Purchase Plan. Read SEC document |
| September 03, 2019 Filed Sep 5, 2019 20:42 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionEmployee Stock Option · Derivative | 6,000 | $0.00 Strike: $0.64 | $0.00 |
DisclosureSEC source: 0000899243-19-022841 · doc4.xml · derivative · entry 3 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 139,404 Underlying: Common Stock · 6,000 shares Expires 2027-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was April 3, 2017. Read SEC document |
| September 03, 2019 Filed Sep 5, 2019 20:42 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 6,000 | $18.74 | $112,419.00 |
DisclosureSEC source: 0000899243-19-022841 · doc4.xml · nonDerivative · entry 2 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $18.36 to $19.00. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| September 03, 2019 Filed Sep 5, 2019 20:42 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionCommon Stock | 6,000 | $0.64 | $3,840.00 |
DisclosureSEC source: 0000899243-19-022841 · doc4.xml · nonDerivative · entry 1 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| September 03, 2019 Filed Sep 5, 2019 20:40 UTC |
Seymour AlbertChief Scientific Officer
|
SaleCommon Stock | 9,300 | $18.74 | $174,283.86 |
DisclosureSEC source: 0000899243-19-022840 · doc4.xml · nonDerivative · entry 1 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 191,050 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $18.29 to $19.06. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| September 03, 2019 Filed Sep 5, 2019 20:39 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
SaleCommon Stock | 12,500 | $18.75 | $234,320.00 |
DisclosureSEC source: 0000899243-19-022839 · doc4.xml · nonDerivative · entry 1 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 140,005 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $18.30 to $19.06. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| August 01, 2019 Filed Aug 5, 2019 20:16 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionEmployee Stock Option · Derivative | 6,000 | $0.00 Strike: $0.64 | $0.00 |
DisclosureSEC source: 0000899243-19-020992 · doc4.xml · derivative · entry 3 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 145,404 Underlying: Common Stock · 6,000 shares Expires 2027-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was April 3, 2017. Read SEC document |
| August 01, 2019 Filed Aug 5, 2019 20:16 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 6,000 | $17.37 | $104,190.60 |
DisclosureSEC source: 0000899243-19-020992 · doc4.xml · nonDerivative · entry 2 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.73 to $17.68. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| August 01, 2019 Filed Aug 5, 2019 20:16 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionCommon Stock | 6,000 | $0.64 | $3,840.00 |
DisclosureSEC source: 0000899243-19-020992 · doc4.xml · nonDerivative · entry 1 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| August 01, 2019 Filed Aug 5, 2019 20:15 UTC |
TZIANABOS ARTHURDirector · President & CEO
|
SaleCommon Stock | 12,500 | $17.37 | $217,111.25 |
DisclosureSEC source: 0000899243-19-020990 · doc4.xml · nonDerivative · entry 1 TZIANABOS ARTHUR · CIK 0001586226 · Director · President & CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 152,505 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.88 to $17.66. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| August 01, 2019 Filed Aug 5, 2019 20:18 UTC |
Seymour AlbertChief Scientific Officer
|
SaleCommon Stock | 9,300 | $17.37 | $161,523.33 |
DisclosureSEC source: 0000899243-19-020993 · doc4.xml · nonDerivative · entry 1 Seymour Albert · CIK 0001735324 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 200,350 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $16.87 to $17.65. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| July 11, 2019 Filed Jul 15, 2019 21:36 UTC |
REICIN ALISEDirector
|
GrantOption (Right to Buy) · Derivative | 31,160 | $0.00 Strike: $19.25 | $0.00 |
DisclosureSEC source: 0000899243-19-019625 · doc4.xml · derivative · entry 1 REICIN ALISE · CIK 0001757533 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 31,160 Underlying: Common Stock · 31,160 shares Expires 2029-07-11 F1 · derivative.exercise_date: The option vests and becomes exercisable in three substantially equal annual installments following the date of grant, subject to the Non-Employee Director continuing service on the Board as a Non-Employee Director through each such vesting date. Read SEC document |
| July 09, 2019 Filed Jul 11, 2019 16:30 UTC |
Rasty SiyamakChief Operating Officer
|
SaleCommon Stock | 8,000 | $20.00 | $160,000.00 |
DisclosureSEC source: 0000899243-19-019474 · doc4.xml · nonDerivative · entry 1 Rasty Siyamak · CIK 0001735450 · Chief Operating Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 222,707 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. Read SEC document |
| July 01, 2019 Filed Jul 3, 2019 20:30 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionEmployee Stock Option · Derivative | 6,000 | $0.00 Strike: $0.64 | $0.00 |
DisclosureSEC source: 0000899243-19-019175 · doc4.xml · derivative · entry 3 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 151,404 Underlying: Common Stock · 6,000 shares Expires 2027-04-05 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The option vested and became exercisable as to 25% of the total grant on the first anniversary of the vesting commencement date and vests in equal monthly installments over a three year period thereafter. The vesting commencement date for this option was April 3, 2017. Read SEC document |
| July 01, 2019 Filed Jul 3, 2019 20:30 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
SaleCommon Stock | 6,000 | $19.00 | $113,971.20 |
DisclosureSEC source: 0000899243-19-019175 · doc4.xml · nonDerivative · entry 2 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018. F2 · price: The price reported is a weighted average price. The shares were sold in multiple transactions at per share prices ranging from $18.53 to $19.48. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Read SEC document |
| July 01, 2019 Filed Jul 3, 2019 20:30 UTC |
Smith W BradfordCFO, Treasurer & Secretary
|
Exercise / conversionCommon Stock | 6,000 | $0.64 | $3,840.00 |
DisclosureSEC source: 0000899243-19-019175 · doc4.xml · nonDerivative · entry 1 Smith W Bradford · CIK 0001317678 · CFO, Treasurer & Secretary 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.