Tapewire

Nasdaq · USD

QTTB

Q32 Bio Inc.

Export transactions ↓
Tapewire entity
5594
SEC CIK
0001661998
Parsed reports
295

Last 12 months

Inside the activity.

4 purchase rows · 11 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202502
Jan 202600
Feb 202603
Mar 202600
Apr 202600
May 202640
Jun 202600
Jul 202600
Aug 202603
Sep 202600
Oct 202603

Latest available

Insider transactions

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
October 06, 2026 Filed Oct 14, 2026 21:30 UTC
Violette Shelia M.Chief Scientific Officer
SaleCommon Stock 917 $8.32 $7,629.16
Disclosure

SEC source: 0001193125-26-421835 · ownership.xml · nonDerivative · entry 1

Violette Shelia M. · CIK 0002016144 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,854

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of performance-based restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $8.07 to $8.32. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
October 06, 2026 Filed Oct 14, 2026 21:30 UTC
Morrison Jodie PopeDirector · CEO
SaleCommon Stock 3,221 $8.32 $26,798.08
Disclosure

SEC source: 0001193125-26-421836 · ownership.xml · nonDerivative · entry 1

Morrison Jodie Pope · CIK 0001618247 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 340,038

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of performance-based restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $8.08 to $8.32. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
October 06, 2026 Filed Oct 14, 2026 21:30 UTC
Kalowski LeeCFO and President
SaleCommon Stock 1,301 $8.32 $10,824.06
Disclosure

SEC source: 0001193125-26-421834 · ownership.xml · nonDerivative · entry 1

Kalowski Lee · CIK 0001618273 · CFO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 137,170

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of performance-based restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $8.08 to $8.32. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
August 25, 2026 Filed Aug 27, 2026 20:10 UTC
Violette Shelia M.Chief Scientific Officer
SaleCommon Stock 2,798 $16.56 $46,334.88
Disclosure

SEC source: 0001193125-26-371291 · ownership.xml · nonDerivative · entry 1

Violette Shelia M. · CIK 0002016144 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 127,771

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

Read SEC document
August 25, 2026 Filed Aug 27, 2026 20:10 UTC
Kalowski LeeCFO and President
SaleCommon Stock 3,972 $16.56 $65,776.32
Disclosure

SEC source: 0001193125-26-371293 · ownership.xml · nonDerivative · entry 1

Kalowski Lee · CIK 0001618273 · CFO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 138,471

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

Read SEC document
August 25, 2026 Filed Aug 27, 2026 20:10 UTC
Morrison Jodie PopeDirector · CEO
SaleCommon Stock 9,845 $16.56 $163,033.20
Disclosure

SEC source: 0001193125-26-371292 · ownership.xml · nonDerivative · entry 1

Morrison Jodie Pope · CIK 0001618247 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 343,259

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

Read SEC document
July 16, 2026 Filed Jul 21, 2026 01:31 UTC
Violette Shelia M.Chief Scientific Officer
GrantCommon Stock 37,500 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-309331 · ownership.xml · nonDerivative · entry 1

Violette Shelia M. · CIK 0002016144 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,569

F1 · kind: Represents shares of Issuer common stock underlying performance-based restricted stock units ("PSUs") granted on July 6, 2026, which vested on July 16, 2026 with respect to a performance-based condition, upon achievement of the closing of a financing of at least $100,000,000 in gross proceeds on or before December 31, 2026. Such PSUs are also subject to a time-based condition, which provides that the PSUs shall vest in equal quarterly installments over three years from July 1, 2026, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. Each PSU represents a contingent right to receive one share of Issuer common stock.

Read SEC document
July 16, 2026 Filed Jul 21, 2026 01:25 UTC
Kalowski LeeCFO and President
GrantCommon Stock 53,250 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-309324 · ownership.xml · nonDerivative · entry 1

Kalowski Lee · CIK 0001618273 · CFO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 142,443

F1 · kind: Represents shares of Issuer common stock underlying performance-based restricted stock units ("PSUs") granted on July 6, 2026, which vested on July 16, 2026 with respect to a performance-based condition, upon achievement of the closing of a financing of at least $100,000,000 in gross proceeds on or before December 31, 2026. Such PSUs are also subject to a time-based condition, which provides that the PSUs shall vest in equal quarterly installments over three years from July 1, 2026, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. Each PSU represents a contingent right to receive one share of Issuer common stock.

Read SEC document
July 16, 2026 Filed Jul 21, 2026 01:27 UTC
Morrison Jodie PopeDirector · CEO
GrantCommon Stock 132,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-309327 · ownership.xml · nonDerivative · entry 1

Morrison Jodie Pope · CIK 0001618247 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 353,104

F1 · kind: Represents shares of Issuer common stock underlying performance-based restricted stock units ("PSUs") granted on July 6, 2026, which vested on July 16, 2026 with respect to a performance-based condition, upon achievement of the closing of a financing of at least $100,000,000 in gross proceeds on or before December 31, 2026. Such PSUs are also subject to a time-based condition, which provides that the PSUs shall vest in equal quarterly installments over three years from July 1, 2026, subject to the Reporting Person's continued service to the Issuer through each applicable vesting date. Each PSU represents a contingent right to receive one share of Issuer common stock.

Read SEC document
June 30, 2026 Filed Jul 2, 2026 20:30 UTC
Manke IsaacDirector
Exercise / conversionStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-26-294694 · ownership.xml · derivative · entry 2

Manke Isaac · CIK 0001622769 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The shares underlying this option are fully vested and exercisable.

Read SEC document
June 30, 2026 Filed Jul 2, 2026 20:30 UTC
Manke IsaacDirector
Exercise / conversionCommon Stock 53,521 $2.80 $149,858.80
Disclosure

SEC source: 0001193125-26-294694 · ownership.xml · nonDerivative · entry 1

Manke Isaac · CIK 0001622769 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272701 · ownership.xml · derivative · entry 1

LAPORTE KATHLEEN · CIK 0001196201 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC
Manke IsaacDirector
GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272698 · ownership.xml · derivative · entry 1

Manke Isaac · CIK 0001622769 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272700 · ownership.xml · derivative · entry 1

Iwicki Mark T · CIK 0001415537 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC
Thistle MaryDirector
GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272690 · ownership.xml · derivative · entry 1

Thistle Mary · CIK 0001317917 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272697 · ownership.xml · derivative · entry 1

TZIANABOS ARTHUR · CIK 0001586226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272692 · ownership.xml · derivative · entry 1

GRAYZEL DAVID S. · CIK 0001732786 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F2 · ownership.direct: This option was granted to the Reporting Person, a director of the Issuer. The proceeds of any sale of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Life Science Advisors, LLC and as such, the Reporting Person disclaims ownership of such securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC
Xu DiyongDirector · 10% owner
GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272686 · ownership.xml · derivative · entry 1

Xu Diyong · CIK 0001995088 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F2 · ownership.direct: Pursuant to an agreement with OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, the Reporting Person is obligated to transfer any securities issued under any such stock options or other awards, or the economic benefit thereof, to OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, which will in turn ensure that such securities or economic benefits are provided to OrbiMed Private Investments VII, LP.

Read SEC document
June 12, 2026 Filed Jun 16, 2026 20:30 UTC GrantStock Option (Right to Buy) · Derivative 9,810 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-272684 · ownership.xml · derivative · entry 1

Lundberg Sven Ante · CIK 0001682126 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,810

Underlying: Common Stock · 9,810 shares

Expires 2036-06-11

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:39 UTC Amendment GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310980 · ownership.xml · derivative · entry 1

LAPORTE KATHLEEN · CIK 0001196201 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:25 UTC Amendment
Manke IsaacDirector
GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310969 · ownership.xml · derivative · entry 1

Manke Isaac · CIK 0001622769 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:37 UTC Amendment GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310978 · ownership.xml · derivative · entry 1

Iwicki Mark T · CIK 0001415537 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:22 UTC Amendment
Thistle MaryDirector
GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310965 · ownership.xml · derivative · entry 1

Thistle Mary · CIK 0001317917 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:40 UTC Amendment GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310983 · ownership.xml · derivative · entry 1

TZIANABOS ARTHUR · CIK 0001586226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:39 UTC Amendment GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310982 · ownership.xml · derivative · entry 1

Lundberg Sven Ante · CIK 0001682126 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:25 UTC Amendment
Xu DiyongDirector · 10% owner
GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310970 · ownership.xml · derivative · entry 1

Xu Diyong · CIK 0001995088 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F3 · ownership.direct: Pursuant to an agreement with OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, the Reporting Person is obligated to transfer any securities issued under any such stock options or other awards, or the economic benefit thereof, to OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, which will in turn ensure that such securities or economic benefits are provided to OrbiMed Private Investments VII, LP.

Read SEC document
June 12, 2026 Filed Jul 22, 2026 00:24 UTC Amendment GrantStock Option (Right to Buy) · Derivative 10,826 $0.00 Strike: $12.64 $0.00
Disclosure

SEC source: 0001193125-26-310967 · ownership.xml · derivative · entry 1

GRAYZEL DAVID S. · CIK 0001732786 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,826

Underlying: Common Stock · 10,826 shares

Expires 2036-06-11

F1 · shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F2 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F1 · derivative.underlying_shares: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F1 · balance_after: This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026.

F3 · ownership.direct: This option was granted to the Reporting Person, a director of the Issuer. The proceeds of any sale of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Life Science Advisors, LLC and as such, the Reporting Person disclaims ownership of such securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

Read SEC document
May 28, 2026 Filed Jun 2, 2026 01:13 UTC
ORBIMED ADVISORS LLCDirector · 10% owner
OrbiMed Capital GP VII LLCDirector · 10% owner
OrbiMed Genesis GP LLCDirector · 10% owner
PurchaseCommon Stock 625,000 $8.00 $5,000,000.00
Disclosure

SEC source: 0000947871-26-000593 · ownership.xml · nonDerivative · entry 2

ORBIMED ADVISORS LLC · CIK 0001055951 · Director · 10% owner

OrbiMed Capital GP VII LLC · CIK 0001760648 · Director · 10% owner

OrbiMed Genesis GP LLC · CIK 0001808744 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 625,000

F1 · shares: These shares of the Issuer's common stock were purchased from the Issuer in a private placement.

F3 · ownership.nature: These securities are held of record by OrbiMed Genesis Master Fund, L.P. ("Genesis"). OrbiMed Genesis GP LLC ("Genesis GP") is the general partner of Genesis and OrbiMed Advisors is the managing member of Genesis GP. By virtue of such relationships, Genesis GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by Genesis and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by Genesis.

F4 · ownership.nature: This report on Form 4 is jointly filed by OrbiMed Advisors, OrbiMed GP, and Genesis GP. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. The Reporting Persons have designated a representative, Diyong Xu, an employee of OrbiMed Advisors, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any such person or entity, including the Reporting Persons, is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
May 28, 2026 Filed Jun 2, 2026 01:13 UTC
ORBIMED ADVISORS LLCDirector · 10% owner
OrbiMed Capital GP VII LLCDirector · 10% owner
OrbiMed Genesis GP LLCDirector · 10% owner
PurchaseCommon Stock 1,250,000 $8.00 $10,000,000.00
Disclosure

SEC source: 0000947871-26-000593 · ownership.xml · nonDerivative · entry 1

ORBIMED ADVISORS LLC · CIK 0001055951 · Director · 10% owner

OrbiMed Capital GP VII LLC · CIK 0001760648 · Director · 10% owner

OrbiMed Genesis GP LLC · CIK 0001808744 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,502,987

F1 · shares: These shares of the Issuer's common stock were purchased from the Issuer in a private placement.

F2 · ownership.nature: These securities are held of record by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital GP VII LLC ("OrbiMed GP") is the general partner of OPI VII and OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of OrbiMed GP. By virtue of such relationships, OrbiMed GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OPI VII and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by OPI VII.

F4 · ownership.nature: This report on Form 4 is jointly filed by OrbiMed Advisors, OrbiMed GP, and Genesis GP. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. The Reporting Persons have designated a representative, Diyong Xu, an employee of OrbiMed Advisors, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any such person or entity, including the Reporting Persons, is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
May 28, 2026 Filed Jun 2, 2026 01:15 UTC
Xu DiyongDirector · 10% owner
PurchaseCommon Stock 625,000 $8.00 $5,000,000.00
Disclosure

SEC source: 0000947871-26-000594 · ownership.xml · nonDerivative · entry 2

Xu Diyong · CIK 0001995088 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 625,000

F1 · shares: These shares of the Issuer's common stock were purchased from the Issuer in a private placement.

F3 · ownership.nature: These securities are held of record by OrbiMed Genesis Master Fund, L.P. ("Genesis"). OrbiMed Genesis GP LLC ("Genesis GP") is the general partner of Genesis and OrbiMed Advisors is the managing member of Genesis GP. By virtue of such relationships, Genesis GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by Genesis and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by Genesis.

F4 · ownership.nature: Each of the Reporting Person, OrbiMed Advisors, OrbiMed GP, and Genesis GP disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any such person or entity is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
May 28, 2026 Filed Jun 2, 2026 01:15 UTC
Xu DiyongDirector · 10% owner
PurchaseCommon Stock 1,250,000 $8.00 $10,000,000.00
Disclosure

SEC source: 0000947871-26-000594 · ownership.xml · nonDerivative · entry 1

Xu Diyong · CIK 0001995088 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 3,502,987

F1 · shares: These shares of the Issuer's common stock were purchased from the Issuer in a private placement.

F2 · ownership.nature: These securities are held of record by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital GP VII LLC ("OrbiMed GP") is the general partner of OPI VII and OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of OrbiMed GP. By virtue of such relationships, OrbiMed GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OPI VII and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and W. Carter Neild, each of whom disclaims beneficial ownership of the shares held by OPI VII.

F4 · ownership.nature: Each of the Reporting Person, OrbiMed Advisors, OrbiMed GP, and Genesis GP disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report shall not be deemed an admission that any such person or entity is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
February 25, 2026 Filed Feb 28, 2026 00:00 UTC
Violette Shelia M.Chief Scientific Officer
SaleCommon Stock 2,815 $4.51 $12,708.04
Disclosure

SEC source: 0001193125-26-083584 · ownership.xml · nonDerivative · entry 1

Violette Shelia M. · CIK 0002016144 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,569

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.35 to $4.69. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
February 25, 2026 Filed Feb 28, 2026 00:00 UTC
Kalowski LeeCFO and President
SaleCommon Stock 3,995 $4.51 $18,035.03
Disclosure

SEC source: 0001193125-26-083588 · ownership.xml · nonDerivative · entry 1

Kalowski Lee · CIK 0001618273 · CFO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,943

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.35 to $4.69. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
February 25, 2026 Filed Feb 28, 2026 00:00 UTC
Morrison Jodie PopeDirector · CEO
SaleCommon Stock 9,896 $4.51 $44,674.50
Disclosure

SEC source: 0001193125-26-083585 · ownership.xml · nonDerivative · entry 1

Morrison Jodie Pope · CIK 0001618247 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,104

F1 · kind: Represents shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. These sales were automatic and not in the discretion of the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $4.35 to $4.69. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, on request, full information regarding the number of shares sold at each separate price within the range set forth above.

Read SEC document
February 24, 2026 Filed Mar 20, 2026 23:00 UTC
Violette Shelia M.Chief Scientific Officer
GrantCommon Stock 37,500 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-118054 · ownership.xml · nonDerivative · entry 1

Violette Shelia M. · CIK 0002016144 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 93,069

F1 · kind: The restricted stock units ("RSUs") vest in four equal installments, 25% shall vest 6 months from February 24, 2026 (the "Grant Date"), 25% shall vest 12 months from the Grant Date, 25% shall vest 24 months from the Grant Date, and 25% shall vest 36 months from Grant Date. Each RSU represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 24, 2026 Filed Mar 20, 2026 23:00 UTC
Kalowski LeeCFO and President
GrantCommon Stock 53,250 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-118052 · ownership.xml · nonDerivative · entry 1

Kalowski Lee · CIK 0001618273 · CFO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,193

F1 · kind: The restricted stock units ("RSUs") vest in four equal installments, 25% shall vest 6 months from February 24, 2026 (the "Grant Date"), 25% shall vest 12 months from the Grant Date, 25% shall vest 24 months from the Grant Date, and 25% shall vest 36 months from Grant Date. Each RSU represents a contingent right to receive one share of Issuer common stock.

Read SEC document
February 24, 2026 Filed Mar 20, 2026 23:00 UTC
Morrison Jodie PopeDirector · CEO
GrantCommon Stock 132,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-118053 · ownership.xml · nonDerivative · entry 1

Morrison Jodie Pope · CIK 0001618247 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 221,104

F1 · kind: The restricted stock units ("RSUs") vest in four equal installments, 25% shall vest 6 months from February 24, 2026 (the "Grant Date"), 25% shall vest 12 months from the Grant Date, 25% shall vest 24 months from the Grant Date, and 25% shall vest 36 months from Grant Date. Each RSU represents a contingent right to receive one share of Issuer common stock.

Read SEC document
January 15, 2026 Filed Jan 31, 2026 00:00 UTC GrantStock Option (Right to Buy) · Derivative 23,272 $2.75 Strike: $3.60 $63,998.00
Disclosure

SEC source: 0001193125-26-032248 · ownership.xml · derivative · entry 1

LAPORTE KATHLEEN · CIK 0001196201 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,272

Underlying: Common Stock · 23,272 shares

Expires 2036-01-14

F1 · price: This option was granted to the Reporting Person, a director of the Issuer pursuant to the 2024 Stock Option and Incentive Plan and pursuant to the Issuer's non-employee director compensation policy. This option shall vest in four equal quarterly installments as of the last date of each calendar quarter subject to the Reporting Person's continued service through such date and represents the Reporting Person's election to receive stock options in lieu of cash retainer fees. Due to administrative oversight this option award initially was not reported.

F1 · derivative.exercise_date: This option was granted to the Reporting Person, a director of the Issuer pursuant to the 2024 Stock Option and Incentive Plan and pursuant to the Issuer's non-employee director compensation policy. This option shall vest in four equal quarterly installments as of the last date of each calendar quarter subject to the Reporting Person's continued service through such date and represents the Reporting Person's election to receive stock options in lieu of cash retainer fees. Due to administrative oversight this option award initially was not reported.

Read SEC document
January 15, 2026 Filed Jan 31, 2026 00:00 UTC GrantStock Option (Right to Buy) · Derivative 16,363 $2.75 Strike: $3.60 $44,998.25
Disclosure

SEC source: 0001193125-26-032247 · ownership.xml · derivative · entry 1

GRAYZEL DAVID S. · CIK 0001732786 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,363

Underlying: Common Stock · 16,363 shares

Expires 2036-01-14

F1 · price: This option was granted to the Reporting Person, a director of the Issuer pursuant to the 2024 Stock Option and Incentive Plan and pursuant to the Issuer's non-employee director compensation policy. This option shall vest in four equal quarterly installments as of the last date of each calendar quarter subject to the Reporting Person's continued service through such date and represents the Reporting Person's election to receive stock options in lieu of cash retainer fees. Due to administrative oversight this option award initially was not reported.

F1 · derivative.exercise_date: This option was granted to the Reporting Person, a director of the Issuer pursuant to the 2024 Stock Option and Incentive Plan and pursuant to the Issuer's non-employee director compensation policy. This option shall vest in four equal quarterly installments as of the last date of each calendar quarter subject to the Reporting Person's continued service through such date and represents the Reporting Person's election to receive stock options in lieu of cash retainer fees. Due to administrative oversight this option award initially was not reported.

F2 · ownership.direct: This option was granted to the Reporting Person, a director of the Issuer. The proceeds of any sale of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Life Science Advisors, LLC and as such, the Reporting Person disclaims ownership of such securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

Read SEC document
January 15, 2026 Filed Jan 31, 2026 00:00 UTC GrantStock Option (Right to Buy) · Derivative 20,363 $2.75 Strike: $3.60 $55,998.25
Disclosure

SEC source: 0001193125-26-032246 · ownership.xml · derivative · entry 1

Lundberg Sven Ante · CIK 0001682126 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,363

Underlying: Common Stock · 20,363 shares

Expires 2036-01-14

F1 · price: This option was granted to the Reporting Person, a director of the Issuer pursuant to the 2024 Stock Option and Incentive Plan and pursuant to the Issuer's non-employee director compensation policy. This option shall vest in four equal quarterly installments as of the last date of each calendar quarter subject to the Reporting Person's continued service through such date and represents the Reporting Person's election to receive stock options in lieu of cash retainer fees. Due to administrative oversight this option award initially was not reported.

F1 · derivative.exercise_date: This option was granted to the Reporting Person, a director of the Issuer pursuant to the 2024 Stock Option and Incentive Plan and pursuant to the Issuer's non-employee director compensation policy. This option shall vest in four equal quarterly installments as of the last date of each calendar quarter subject to the Reporting Person's continued service through such date and represents the Reporting Person's election to receive stock options in lieu of cash retainer fees. Due to administrative oversight this option award initially was not reported.

Read SEC document
December 02, 2025 Filed Dec 5, 2025 00:00 UTC
Kalowski LeeCFO and President
SaleCommon Stock 9,072 $3.46 $31,395.47
Disclosure

SEC source: 0001193125-25-308327 · ownership.xml · nonDerivative · entry 1

Kalowski Lee · CIK 0001618273 · CFO and President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,938

Read SEC document
December 02, 2025 Filed Dec 5, 2025 00:00 UTC
Morrison Jodie PopeDirector · CEO
SaleCommon Stock 22,506 $3.46 $77,870.76
Disclosure

SEC source: 0001193125-25-308328 · ownership.xml · nonDerivative · entry 1

Morrison Jodie Pope · CIK 0001618247 · Director · CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 99,000

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:16 UTC GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251978 · ownership.xml · derivative · entry 1

LAPORTE KATHLEEN · CIK 0001196201 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:26 UTC
Manke IsaacDirector
GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251993 · ownership.xml · derivative · entry 1

Manke Isaac · CIK 0001622769 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:26 UTC GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251994 · ownership.xml · derivative · entry 1

Iwicki Mark T · CIK 0001415537 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:19 UTC
Thistle MaryDirector
GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251986 · ownership.xml · derivative · entry 1

Thistle Mary · CIK 0001317917 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:16 UTC GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251981 · ownership.xml · derivative · entry 1

TZIANABOS ARTHUR · CIK 0001586226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:17 UTC GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251983 · ownership.xml · derivative · entry 1

GRAYZEL DAVID S. · CIK 0001732786 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F2 · ownership.direct: This option was granted to the Reporting Person, a director of the Issuer. The proceeds of any sale of shares of common stock issued to the Reporting Person upon exercise of this option will be transferred to Atlas Venture Life Science Advisors, LLC and as such, the Reporting Person disclaims ownership of such securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of his pecuniary interest therein, if any.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:34 UTC GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-252000 · ownership.xml · derivative · entry 1

Lundberg Sven Ante · CIK 0001682126 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
October 23, 2025 Filed Oct 28, 2025 01:25 UTC
Xu DiyongDirector
GrantStock Option (Right to Buy) · Derivative 53,521 $0.00 Strike: $2.80 $0.00
Disclosure

SEC source: 0001193125-25-251992 · ownership.xml · derivative · entry 1

Xu Diyong · CIK 0001995088 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,521

Underlying: Common Stock · 53,521 shares

Expires 2035-10-22

F1 · derivative.exercise_date: The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date.

F2 · ownership.direct: Pursuant to an agreement with OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, the Reporting Person is obligated to transfer any securities issued under any such stock options or other awards, or the economic benefit thereof, to OrbiMed Advisors LLC and OrbiMed Capital GP VII LLC, which will in turn ensure that such securities or economic benefits are provided to OrbiMed Private Investments VII, LP.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.