Last 12 months
Inside the activity.
15 purchase rows · 2 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 0 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 0 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 0 |
| Apr 2026 | 0 | 0 |
| May 2026 | 1 | 0 |
| Jun 2026 | 4 | 0 |
| Jul 2026 | 0 | 2 |
| Aug 2026 | 3 | 0 |
| Sep 2026 | 4 | 0 |
| Oct 2026 | 3 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| July 17, 2017 Filed Jul 19, 2017 16:10 UTC |
HENNEY CHRISTOPHER SDirector
|
SaleOrdinary Shares, par value $0.01 per share | 5,000 | $66.13 | $330,670.50 |
DisclosureSEC source: 0000899243-17-018555 · doc4.xml · nonDerivative · entry 2 HENNEY CHRISTOPHER S · CIK 0001242880 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $66.00 to $66.30, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| July 17, 2017 Filed Jul 19, 2017 16:10 UTC |
HENNEY CHRISTOPHER SDirector
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 5,000 | $6.65 | $33,250.00 |
DisclosureSEC source: 0000899243-17-018555 · doc4.xml · nonDerivative · entry 1 HENNEY CHRISTOPHER S · CIK 0001242880 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| July 17, 2017 Filed Jul 19, 2017 20:05 UTC |
Walker Karin LSee Remarks
|
Exercise / conversionStock Option(right to buy) · Derivative | 5,000 | $0.00 Strike: $9.75 | $0.00 |
DisclosureSEC source: 0000899243-17-018551 · doc4.xml · derivative · entry 4 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 5,000 shares Expires 2023-06-02 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on May 20, 2014 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. Read SEC document |
| July 17, 2017 Filed Jul 19, 2017 20:05 UTC |
Walker Karin LSee Remarks
|
SaleOrdinary Shares, par value $0.01 per share | 3,600 | $65.21 | $234,754.92 |
DisclosureSEC source: 0000899243-17-018551 · doc4.xml · nonDerivative · entry 3 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F3 · price: The transaction was executed in multiple trades in prices ranging from $64.69 to $65.63, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| July 17, 2017 Filed Jul 19, 2017 20:05 UTC |
Walker Karin LSee Remarks
|
SaleOrdinary Shares, par value $0.01 per share | 1,400 | $64.06 | $89,684.56 |
DisclosureSEC source: 0000899243-17-018551 · doc4.xml · nonDerivative · entry 2 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,600 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $63.65 to $64.62, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| July 17, 2017 Filed Jul 19, 2017 20:05 UTC |
Walker Karin LSee Remarks
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 5,000 | $9.75 | $48,750.00 |
DisclosureSEC source: 0000899243-17-018551 · doc4.xml · nonDerivative · entry 1 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| July 07, 2017 Filed Jul 7, 2017 21:02 UTC |
Selkoe Dennis J.Director
|
Exercise / conversionStock Option (right to buy) · Derivative | 3,500 | $0.00 Strike: $16.42 | $0.00 |
DisclosureSEC source: 0000899243-17-018074 · doc4.xml · derivative · entry 5 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 7,000 Underlying: Ordinary Shares · 3,500 shares Expires 2023-07-21 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| July 07, 2017 Filed Jul 7, 2017 21:02 UTC |
Selkoe Dennis J.Director
|
SaleOrdinary Shares, par value $0.01 per share | 500 | $58.55 | $29,274.00 |
DisclosureSEC source: 0000899243-17-018074 · doc4.xml · nonDerivative · entry 3 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,845 F1 · kind: The sale reported on this Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F3 · price: The transaction was executed in multiple trades in prices ranging from $58.52 to $58.57, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| July 07, 2017 Filed Jul 7, 2017 21:02 UTC |
Selkoe Dennis J.Director
|
SaleOrdinary Shares, par value $0.01 per share | 3,000 | $58.04 | $174,124.80 |
DisclosureSEC source: 0000899243-17-018074 · doc4.xml · nonDerivative · entry 2 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,345 F1 · kind: The sale reported on this Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $57.49 to $58.46, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| July 07, 2017 Filed Jul 7, 2017 21:02 UTC |
Selkoe Dennis J.Director
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 3,500 | $16.42 | $57,470.00 |
DisclosureSEC source: 0000899243-17-018074 · doc4.xml · nonDerivative · entry 1 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,345 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| June 09, 2017 Filed Jun 13, 2017 20:07 UTC |
Zago Wagner M.Chief Scientific Officer
|
GrantStock Option (right to buy) · Derivative | 20,000 | $0.00 Strike: $51.32 | $0.00 |
DisclosureSEC source: 0000899243-17-016222 · doc4.xml · derivative · entry 1 Zago Wagner M. · CIK 0001708681 · Chief Scientific Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Ordinary Shares · 20,000 shares Expires 2027-06-09 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on June 9, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| May 18, 2017 Filed May 19, 2017 20:05 UTC |
COLLIER RICHARD TDirector
|
GrantStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $56.23 | $0.00 |
DisclosureSEC source: 0000899243-17-013893 · doc4.xml · derivative · entry 2 COLLIER RICHARD T · CIK 0001110751 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Underlying: Ordinary Shares · 12,000 shares Expires 2027-05-18 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual general meeting in 2018 of the Issuer's shareholders, assuming continuous service as a director until such vesting date. Read SEC document |
| May 18, 2017 Filed May 19, 2017 20:05 UTC |
Cooke ShaneDirector
|
GrantStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $56.23 | $0.00 |
DisclosureSEC source: 0000899243-17-013891 · doc4.xml · derivative · entry 1 Cooke Shane · CIK 0001524823 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Underlying: Ordinary Shares · 12,000 shares Expires 2027-05-18 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual general meeting in 2018 of the Issuer's shareholders, assuming continuous service as a director until such vesting date. Read SEC document |
| May 18, 2017 Filed May 19, 2017 16:07 UTC |
HENNEY CHRISTOPHER SDirector
|
GrantStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $56.23 | $0.00 |
DisclosureSEC source: 0000899243-17-013899 · doc4.xml · derivative · entry 1 HENNEY CHRISTOPHER S · CIK 0001242880 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Underlying: Ordinary Shares · 12,000 shares Expires 2027-05-18 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual general meeting in 2018 of the Issuer's shareholders, assuming continuous service as a director until such vesting date. Read SEC document |
| May 18, 2017 Filed May 19, 2017 20:08 UTC |
Ekman LarsDirector
|
GrantStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $56.23 | $0.00 |
DisclosureSEC source: 0000899243-17-013904 · doc4.xml · derivative · entry 2 Ekman Lars · CIK 0001376117 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Underlying: Ordinary Shares · 12,000 shares Expires 2027-05-18 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual general meeting in 2018 of the Issuer's shareholders, assuming continuous service as a director until such vesting date. Read SEC document |
| May 18, 2017 Filed May 19, 2017 20:05 UTC |
Selkoe Dennis J.Director
|
GrantStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $56.23 | $0.00 |
DisclosureSEC source: 0000899243-17-013890 · doc4.xml · derivative · entry 3 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Underlying: Ordinary Shares · 12,000 shares Expires 2027-05-18 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual general meeting in 2018 of the Issuer's shareholders, assuming continuous service as a director until such vesting date. Read SEC document |
| May 18, 2017 Filed May 19, 2017 20:08 UTC |
Harfstrand Karl Anders OlofDirector
|
GrantStock Option (right to buy) · Derivative | 12,000 | $0.00 Strike: $56.23 | $0.00 |
DisclosureSEC source: 0000899243-17-013902 · doc4.xml · derivative · entry 1 Harfstrand Karl Anders Olof · CIK 0001646451 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 12,000 Underlying: Ordinary Shares · 12,000 shares Expires 2027-05-18 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 100% of the total number of shares subject to the option on the earlier of the first anniversary of the grant date or the day prior to the annual general meeting in 2018 of the Issuer's shareholders, assuming continuous service as a director until such vesting date. Read SEC document |
| May 16, 2017 Filed May 18, 2017 16:08 UTC |
Noonberg Sarah B.Chief Medical Officer
|
GrantStock Option (right to buy) · Derivative | 100,000 | $0.00 Strike: $56.37 | $0.00 |
DisclosureSEC source: 0000899243-17-013685 · doc4.xml · derivative · entry 1 Noonberg Sarah B. · CIK 0001706301 · Chief Medical Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100,000 Underlying: Ordinary Shares · 100,000 shares Expires 2027-05-16 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on May 16, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
Exercise / conversionStock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $29.81 | $0.00 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · derivative · entry 7 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,000 Underlying: Ordinary Shares · 2,000 shares Expires 2024-02-04 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 4, 2015 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
Exercise / conversionStock Option (right to buy) · Derivative | 3,000 | $0.00 Strike: $9.75 | $0.00 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · derivative · entry 6 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,000 Underlying: Ordinary Shares · 3,000 shares Expires 2023-06-02 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on May 20, 2014 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
SaleOrdinary Shares, par value $0.01 per share | 2,000 | $52.29 | $104,581.60 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · nonDerivative · entry 5 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F3 · price: The transaction was executed in multiple trades in prices ranging from $51.68 to $52.66, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 2,000 | $29.81 | $59,620.00 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · nonDerivative · entry 4 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
SaleOrdinary Shares, par value $0.01 per share | 100 | $52.70 | $5,270.00 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · nonDerivative · entry 3 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
SaleOrdinary Shares, par value $0.01 per share | 2,900 | $52.21 | $151,410.45 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · nonDerivative · entry 2 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 100 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $51.68 to $52.64, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| April 17, 2017 Filed Apr 19, 2017 20:06 UTC |
Walker Karin LSee Remarks
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 3,000 | $9.75 | $29,250.00 |
DisclosureSEC source: 0000899243-17-010521 · doc4.xml · nonDerivative · entry 1 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 03, 2017 Filed Apr 5, 2017 20:06 UTC |
Selkoe Dennis J.Director
|
Exercise / conversionStock Option (right to buy) · Derivative | 3,500 | $0.00 Strike: $16.42 | $0.00 |
DisclosureSEC source: 0000899243-17-009487 · doc4.xml · derivative · entry 4 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 10,500 Underlying: Ordinary Shares · 3,500 shares Expires 2023-07-21 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 03, 2017 Filed Apr 5, 2017 20:06 UTC |
Selkoe Dennis J.Director
|
SaleOrdinary Shares, par value $0.01 per share | 3,500 | $55.86 | $195,522.95 |
DisclosureSEC source: 0000899243-17-009487 · doc4.xml · nonDerivative · entry 2 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,845 F1 · kind: The sale reported on this Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $55.39 to $56.14, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| April 03, 2017 Filed Apr 5, 2017 20:06 UTC |
Selkoe Dennis J.Director
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 3,500 | $16.42 | $57,470.00 |
DisclosureSEC source: 0000899243-17-009487 · doc4.xml · nonDerivative · entry 1 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,345 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 09, 2017 Filed Mar 9, 2017 21:06 UTC |
Nguyen TranChief Financial Officer
|
PurchaseOrdinary Shares, par value $0.01 per share | 1,000 | $51.32 | $51,317.20 |
DisclosureSEC source: 0000899243-17-006986 · doc4.xml · nonDerivative · entry 1 Nguyen Tran · CIK 0001457013 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,200 F1 · price: The shares were purchased in multiple trades at prices ranging from $51.2492 to $51.46 inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 16:07 UTC |
HOMAN ARTHUR WChief Legal Officer
|
Exercise / conversionStock Option (right to buy) · Derivative | 3,125 | $0.00 Strike: $22.14 | $0.00 |
DisclosureSEC source: 0000899243-17-006351 · doc4.xml · derivative · entry 4 HOMAN ARTHUR W · CIK 0001232119 · Chief Legal Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 68,750 Underlying: Ordinary Shares · 3,125 shares Expires 2024-05-01 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on April 30, 2015 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment or service relationship with the Issuer on each such vesting date. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 16:07 UTC |
HOMAN ARTHUR WChief Legal Officer
|
SaleOrdinary Shares, par value $0.01 per share | 3,125 | $59.28 | $185,257.50 |
DisclosureSEC source: 0000899243-17-006351 · doc4.xml · nonDerivative · entry 2 HOMAN ARTHUR W · CIK 0001232119 · Chief Legal Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $58.86 to $59.785, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 16:07 UTC |
HOMAN ARTHUR WChief Legal Officer
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 3,125 | $22.14 | $69,187.50 |
DisclosureSEC source: 0000899243-17-006351 · doc4.xml · nonDerivative · entry 1 HOMAN ARTHUR W · CIK 0001232119 · Chief Legal Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 3,125 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:16 UTC |
Selkoe Dennis J.Director
|
Exercise / conversionStock Option (right to buy) · Derivative | 3,500 | $0.00 Strike: $16.42 | $0.00 |
DisclosureSEC source: 0000899243-17-006354 · doc4.xml · derivative · entry 4 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 14,000 Underlying: Ordinary Shares · 3,500 shares Expires 2023-07-21 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:16 UTC |
Selkoe Dennis J.Director
|
SaleOrdinary Shares, par value $0.01 per share | 3,500 | $59.25 | $207,364.15 |
DisclosureSEC source: 0000899243-17-006354 · doc4.xml · nonDerivative · entry 2 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,845 F1 · kind: The sale reported on this Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $58.70 to $59.62, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:16 UTC |
Selkoe Dennis J.Director
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 3,500 | $16.42 | $57,470.00 |
DisclosureSEC source: 0000899243-17-006354 · doc4.xml · nonDerivative · entry 1 Selkoe Dennis J. · CIK 0001582306 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,345 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
Exercise / conversionStock Option (right to buy) · Derivative | 25,163 | $0.00 Strike: $6.41 | $0.00 |
DisclosureSEC source: 0000899243-17-006338 · doc4.xml · derivative · entry 4 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 111,874 Underlying: Ordinary Shares · 25,163 shares Expires 2023-01-29 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on January 29, 2014 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
SaleOrdinary Shares, par value $0.01 per share | 12,822 | $61.24 | $785,275.70 |
DisclosureSEC source: 0000899243-17-006338 · doc4.xml · nonDerivative · entry 3 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,793 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F3 · price: The transaction was executed in multiple trades in prices ranging from $61.00 to $61.66, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
SaleOrdinary Shares, par value $0.01 per share | 12,341 | $60.28 | $743,972.25 |
DisclosureSEC source: 0000899243-17-006338 · doc4.xml · nonDerivative · entry 2 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 15,615 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $60.00 to $60.995, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| March 01, 2017 Filed Mar 3, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 25,163 | $6.41 | $161,294.83 |
DisclosureSEC source: 0000899243-17-006338 · doc4.xml · nonDerivative · entry 1 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 27,956 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| February 28, 2017 Filed Mar 2, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
Exercise / conversionStock Option (right to buy) · Derivative | 3,796 | $0.00 Strike: $6.41 | $0.00 |
DisclosureSEC source: 0000899243-17-006027 · doc4.xml · derivative · entry 3 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 137,037 Underlying: Ordinary Shares · 3,796 shares Expires 2023-01-29 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on January 29, 2014 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| February 28, 2017 Filed Mar 2, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
SaleOrdinary Shares, par value $0.01 per share | 3,796 | $60.00 | $227,760.00 |
DisclosureSEC source: 0000899243-17-006027 · doc4.xml · nonDerivative · entry 2 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 2,793 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. Read SEC document |
| February 28, 2017 Filed Mar 2, 2017 21:05 UTC |
Kinney Gene G.Director · President and CEO
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 3,796 | $6.41 | $24,332.36 |
DisclosureSEC source: 0000899243-17-006027 · doc4.xml · nonDerivative · entry 1 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 6,589 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| February 27, 2017 Filed Mar 1, 2017 16:05 UTC |
HENNEY CHRISTOPHER SDirector
|
Exercise / conversionStock Option (right to buy) · Derivative | 5,989 | $0.00 Strike: $6.65 | $0.00 |
DisclosureSEC source: 0000899243-17-005786 · doc4.xml · derivative · entry 3 HENNEY CHRISTOPHER S · CIK 0001242880 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 20,000 Underlying: Ordinary Shares · 5,989 shares Expires 2023-03-18 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F3 · derivative.exercise_date: The shares subject to the option are fully vested and exercisable as of the date hereof. Read SEC document |
| February 27, 2017 Filed Mar 1, 2017 16:05 UTC |
HENNEY CHRISTOPHER SDirector
|
SaleOrdinary Shares, par value $0.01 per share | 5,989 | $57.16 | $342,350.40 |
DisclosureSEC source: 0000899243-17-005786 · doc4.xml · nonDerivative · entry 2 HENNEY CHRISTOPHER S · CIK 0001242880 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 0 F1 · kind: The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. F2 · price: The transaction was executed in multiple trades in prices ranging from $57.00 to $57.80, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. Read SEC document |
| February 27, 2017 Filed Mar 1, 2017 16:05 UTC |
HENNEY CHRISTOPHER SDirector
|
Exercise / conversionOrdinary Shares, par value $0.01 per share | 5,989 | $6.65 | $39,826.85 |
DisclosureSEC source: 0000899243-17-005786 · doc4.xml · nonDerivative · entry 1 HENNEY CHRISTOPHER S · CIK 0001242880 · Director 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 5,989 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| February 22, 2017 Filed Feb 24, 2017 21:05 UTC |
Nguyen TranChief Financial Officer
|
GrantStock Option (right to buy) · Derivative | 75,000 | $0.00 Strike: $55.00 | $0.00 |
DisclosureSEC source: 0000899243-17-005217 · doc4.xml · derivative · entry 2 Nguyen Tran · CIK 0001457013 · Chief Financial Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 75,000 Underlying: Ordinary Shares · 75,000 shares Expires 2027-02-22 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| February 22, 2017 Filed Feb 24, 2017 16:07 UTC |
HOMAN ARTHUR WChief Legal Officer
|
GrantStock Option (right to buy) · Derivative | 55,000 | $0.00 Strike: $55.00 | $0.00 |
DisclosureSEC source: 0000899243-17-005225 · doc4.xml · derivative · entry 2 HOMAN ARTHUR W · CIK 0001232119 · Chief Legal Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 55,000 Underlying: Ordinary Shares · 55,000 shares Expires 2027-02-22 F2 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| February 22, 2017 Filed Feb 24, 2017 21:06 UTC |
Nickerson TaraChief Business Officer
|
GrantStock Option (right to buy) · Derivative | 45,000 | $0.00 Strike: $55.00 | $0.00 |
DisclosureSEC source: 0000899243-17-005223 · doc4.xml · derivative · entry 2 Nickerson Tara · CIK 0001564461 · Chief Business Officer 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 45,000 Underlying: Ordinary Shares · 45,000 shares Expires 2027-02-22 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| February 22, 2017 Filed Feb 24, 2017 21:06 UTC |
Kinney Gene G.Director · President and CEO
|
GrantStock Option (right to buy) · Derivative | 120,000 | $0.00 Strike: $55.00 | $0.00 |
DisclosureSEC source: 0000899243-17-005221 · doc4.xml · derivative · entry 2 Kinney Gene G. · CIK 0001564380 · Director · President and CEO 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 120,000 Underlying: Ordinary Shares · 120,000 shares Expires 2027-02-22 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
| February 22, 2017 Filed Feb 24, 2017 21:05 UTC |
Walker Karin LSee Remarks
|
GrantStock Option (right to buy) · Derivative | 30,000 | $0.00 Strike: $55.00 | $0.00 |
DisclosureSEC source: 0000899243-17-005218 · doc4.xml · derivative · entry 1 Walker Karin L · CIK 0001559422 · See Remarks 10b5-1 filing: Not disclosed Ownership: Direct Disclosed balance after: 30,000 Underlying: Ordinary Shares · 30,000 shares Expires 2027-02-22 F1 · derivative.exercise_date: The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.