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Nasdaq · USD

NERV

Minerva Neurosciences, Inc.

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6245
SEC CIK
0001598646
Parsed reports
199

Last 12 months

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0 purchase rows · 0 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
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MonthPurchasesSales
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Dec 202500
Jan 202600
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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
February 06, 2017 Filed Feb 7, 2017 21:32 UTC
Race GeoffEVP, CFO & CBO
SaleCommon Stock 1,692 $11.00 $18,612.00
Disclosure

SEC source: 0001209191-17-008360 · doc4.xml · nonDerivative · entry 2

Race Geoff · CIK 0001610382 · EVP, CFO & CBO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 185,198

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 15, 2016.

Read SEC document
February 06, 2017 Filed Feb 7, 2017 21:31 UTC
Luthringer RemyDirector · President & CEO
Exercise / conversionStock Option (Right to Buy) · Derivative 2,185 $0.00 Strike: $4.71 $0.00
Disclosure

SEC source: 0001209191-17-008356 · doc4.xml · derivative · entry 7

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 285,719

Underlying: Common Stock · 2,185 shares

Expires 2025-12-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option shall vest as follows: 25% vested on December 4, 2016 and the remainder vests in quarterly installments over 3 years thereafter.

Read SEC document
February 06, 2017 Filed Feb 7, 2017 21:31 UTC
Luthringer RemyDirector · President & CEO
SaleCommon Stock 2,185 $11.00 $24,035.00
Disclosure

SEC source: 0001209191-17-008356 · doc4.xml · nonDerivative · entry 4

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 15, 2016.

Read SEC document
February 06, 2017 Filed Feb 7, 2017 21:31 UTC
Luthringer RemyDirector · President & CEO
Exercise / conversionCommon Stock 2,185 $4.71 $10,291.35
Disclosure

SEC source: 0001209191-17-008356 · doc4.xml · nonDerivative · entry 3

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,185

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
February 03, 2017 Filed Feb 7, 2017 21:32 UTC
Race GeoffEVP, CFO & CBO
SaleCommon Stock 19,758 $11.02 $217,733.16
Disclosure

SEC source: 0001209191-17-008360 · doc4.xml · nonDerivative · entry 1

Race Geoff · CIK 0001610382 · EVP, CFO & CBO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 186,890

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 15, 2016.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $11.00 - $11.10, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote (2) to this Form 4.

Read SEC document
February 03, 2017 Filed Feb 7, 2017 21:31 UTC
Luthringer RemyDirector · President & CEO
Exercise / conversionStock Option (Right to Buy) · Derivative 32,096 $0.00 Strike: $4.71 $0.00
Disclosure

SEC source: 0001209191-17-008356 · doc4.xml · derivative · entry 6

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 287,904

Underlying: Common Stock · 32,096 shares

Expires 2025-12-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option shall vest as follows: 25% vested on December 4, 2016 and the remainder vests in quarterly installments over 3 years thereafter.

Read SEC document
February 03, 2017 Filed Feb 7, 2017 21:31 UTC
Luthringer RemyDirector · President & CEO
SaleCommon Stock 32,096 $11.02 $353,697.92
Disclosure

SEC source: 0001209191-17-008356 · doc4.xml · nonDerivative · entry 2

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 15, 2016.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $11.00 - $11.10, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote (2) to this Form 4.

Read SEC document
February 03, 2017 Filed Feb 7, 2017 21:31 UTC
Luthringer RemyDirector · President & CEO
Exercise / conversionCommon Stock 32,096 $4.71 $151,172.16
Disclosure

SEC source: 0001209191-17-008356 · doc4.xml · nonDerivative · entry 1

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,096

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 11, 2017 Filed Jan 13, 2017 21:30 UTC
Reilly Joseph H.SVP & Chief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 1,600 $0.00 Strike: $4.71 $0.00
Disclosure

SEC source: 0001209191-17-003672 · doc4.xml · derivative · entry 3

Reilly Joseph H. · CIK 0001610499 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,400

Underlying: Common Stock · 1,600 shares

Expires 2025-12-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option shall vest as follows: 25% vested December 14, 2016 and then in quarterly installments over 3 years thereafter.

Read SEC document
January 11, 2017 Filed Jan 13, 2017 21:30 UTC
Reilly Joseph H.SVP & Chief Operating Officer
SaleCommon Stock 1,600 $12.03 $19,248.00
Disclosure

SEC source: 0001209191-17-003672 · doc4.xml · nonDerivative · entry 2

Reilly Joseph H. · CIK 0001610499 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,333

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 12, 2016.

Read SEC document
January 11, 2017 Filed Jan 13, 2017 21:30 UTC
Reilly Joseph H.SVP & Chief Operating Officer
Exercise / conversionCommon Stock 1,600 $4.71 $7,536.00
Disclosure

SEC source: 0001209191-17-003672 · doc4.xml · nonDerivative · entry 1

Reilly Joseph H. · CIK 0001610499 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,933

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 04, 2017 Filed Jan 6, 2017 21:28 UTC
Levine Mark S.SVP,General Counsel & Sec.
Exercise / conversionStock Option (Right to Buy) · Derivative 250 $0.00 Strike: $5.19 $0.00
Disclosure

SEC source: 0001209191-17-002652 · doc4.xml · derivative · entry 5

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,274

Underlying: Common Stock · 250 shares

Expires 2025-04-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vests as follows: 25% on April 14, 2016; and then in quarterly installments over 3 years thereafter.

Read SEC document
January 04, 2017 Filed Jan 6, 2017 21:28 UTC
Levine Mark S.SVP,General Counsel & Sec.
Exercise / conversionStock Option (Right to Buy) · Derivative 17,250 $0.00 Strike: $4.71 $0.00
Disclosure

SEC source: 0001209191-17-002652 · doc4.xml · derivative · entry 4

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,750

Underlying: Common Stock · 17,250 shares

Expires 2025-12-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This option vests as follows: 25% on December 4, 2016 and then in quarterly installments over 3 years thereafter.

Read SEC document
January 04, 2017 Filed Jan 6, 2017 21:28 UTC
Levine Mark S.SVP,General Counsel & Sec.
SaleCommon Stock 17,500 $12.00 $210,000.00
Disclosure

SEC source: 0001209191-17-002652 · doc4.xml · nonDerivative · entry 3

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 22, 2016.

Read SEC document
January 04, 2017 Filed Jan 6, 2017 21:28 UTC
Levine Mark S.SVP,General Counsel & Sec.
Exercise / conversionCommon Stock 250 $5.19 $1,297.50
Disclosure

SEC source: 0001209191-17-002652 · doc4.xml · nonDerivative · entry 2

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 04, 2017 Filed Jan 6, 2017 21:28 UTC
Levine Mark S.SVP,General Counsel & Sec.
Exercise / conversionCommon Stock 17,250 $4.71 $81,247.50
Disclosure

SEC source: 0001209191-17-002652 · doc4.xml · nonDerivative · entry 1

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,250

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 03, 2017 Filed Jan 5, 2017 16:39 UTC
Davidson MichaelChief Medical Officer
GrantStock Option (Right to Buy) · Derivative 145,000 $0.00 Strike: $11.75 $0.00
Disclosure

SEC source: 0001209191-17-002130 · doc4.xml · derivative · entry 1

Davidson Michael · CIK 0001691467 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 145,000

Underlying: Common Stock · 145,000 shares

Expires 2027-01-02

F1 · derivative.exercise_date: The shares underlying the option shall vest and become exercisable as to 25% on January 3, 2018; the balance of the shares underlying the option shall vest and become exercisable in 12 successive equal quarterly installments, in each case so long as the Reporting Person provides continuous service to the Issuer on each such date.

Read SEC document
December 27, 2016 Filed Dec 29, 2016 21:41 UTC
Ahlholm Frederick WSVP, Chief Accounting Officer
Exercise / conversionEmployee Stock Option (Right to Buy) · Derivative 12,000 $0.00 Strike: $4.71 $0.00
Disclosure

SEC source: 0001209191-16-157015 · doc4.xml · derivative · entry 3

Ahlholm Frederick W · CIK 0001405279 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,000

Underlying: Common Stock · 12,000 shares

Expires 2025-12-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option vested as to 25% of the shares on December 4, 2016 and then in quarterly installments over 3 years thereafter.

Read SEC document
December 27, 2016 Filed Dec 29, 2016 21:41 UTC
Ahlholm Frederick WSVP, Chief Accounting Officer
SaleCommon Stock 17,000 $12.51 $212,670.00
Disclosure

SEC source: 0001209191-16-157015 · doc4.xml · nonDerivative · entry 2

Ahlholm Frederick W · CIK 0001405279 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

F1 · kind: These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 22, 2016.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.20 - $13.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote (2) to this Form 4.

Read SEC document
December 27, 2016 Filed Dec 29, 2016 21:41 UTC
Ahlholm Frederick WSVP, Chief Accounting Officer
Exercise / conversionCommon Stock 12,000 $4.71 $56,520.00
Disclosure

SEC source: 0001209191-16-157015 · doc4.xml · nonDerivative · entry 1

Ahlholm Frederick W · CIK 0001405279 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 21:49 UTC
Ahlholm Frederick WSVP, Chief Accounting Officer
GrantEmployee Stock Option (Right to Buy) · Derivative 35,000 $0.00 Strike: $13.45 $0.00
Disclosure

SEC source: 0001209191-16-155671 · doc4.xml · derivative · entry 2

Ahlholm Frederick W · CIK 0001405279 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2026-12-13

F3 · derivative.exercise_price: The exercise price is the closing price of the Issuer's common stock on December 14, 2016.

F4 · derivative.exercise_date: This option shall vest as follows: 25% on December 14, 2017 and then in quarterly installments over 3 years thereafter.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 21:49 UTC
Ahlholm Frederick WSVP, Chief Accounting Officer
GrantRestricted Stock Unit · Derivative 20,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-16-155671 · doc4.xml · derivative · entry 1

Ahlholm Frederick W · CIK 0001405279 · SVP, Chief Accounting Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock

F2 · derivative.exercise_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

F2 · derivative.expiration_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:02 UTC
Reilly Joseph H.SVP & Chief Operating Officer
GrantEmployee Stock Option (Right to Buy) · Derivative 60,000 $0.00 Strike: $13.45 $0.00
Disclosure

SEC source: 0001209191-16-155685 · doc4.xml · derivative · entry 2

Reilly Joseph H. · CIK 0001610499 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2026-12-13

F3 · derivative.exercise_price: The exercise price is the closing price of the Issuer's common stock on December 14, 2016.

F4 · derivative.exercise_date: This option shall vest as follows: 25% on December 14, 2017 and then in quarterly installments over 3 years thereafter.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:02 UTC
Reilly Joseph H.SVP & Chief Operating Officer
GrantRestricted Stock Unit · Derivative 35,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-16-155685 · doc4.xml · derivative · entry 1

Reilly Joseph H. · CIK 0001610499 · SVP & Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock

F2 · derivative.exercise_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

F2 · derivative.expiration_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:04 UTC
Race GeoffEVP, CFO & Chief Business Off.
GrantEmployee Stock Option (Right to Buy) · Derivative 100,000 $0.00 Strike: $13.45 $0.00
Disclosure

SEC source: 0001209191-16-155688 · doc4.xml · derivative · entry 2

Race Geoff · CIK 0001610382 · EVP, CFO & Chief Business Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2026-12-13

F3 · derivative.exercise_price: The exercise price is the closing price of the Issuer's common stock on December 14, 2016.

F4 · derivative.exercise_date: This option shall vest as follows: 25% on December 14, 2017 and then in quarterly installments over 3 years thereafter.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:04 UTC
Race GeoffEVP, CFO & Chief Business Off.
GrantRestricted Stock Unit · Derivative 50,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-16-155688 · doc4.xml · derivative · entry 1

Race Geoff · CIK 0001610382 · EVP, CFO & Chief Business Off.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock

F2 · derivative.exercise_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

F2 · derivative.expiration_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:06 UTC
Luthringer RemyDirector · President & CEO
GrantStock Option (Right to Buy) · Derivative 150,000 $0.00 Strike: $13.45 $0.00
Disclosure

SEC source: 0001209191-16-155690 · doc4.xml · derivative · entry 2

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Common Stock · 150,000 shares

Expires 2026-12-13

F3 · derivative.exercise_price: The exercise price is the closing price of the Issuer's common stock on December 14, 2016.

F4 · derivative.exercise_date: This option shall vest as follows: 25% on December 14, 2017 and then in quarterly installments over 3 years thereafter.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:06 UTC
Luthringer RemyDirector · President & CEO
GrantRestricted Stock Unit · Derivative 75,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-16-155690 · doc4.xml · derivative · entry 1

Luthringer Remy · CIK 0001610384 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock

F2 · derivative.exercise_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

F2 · derivative.expiration_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:01 UTC
Levine Mark S.SVP,General Counsel & Sec.
GrantEmployee Stock Option (Right to Buy) · Derivative 35,000 $0.00 Strike: $13.45 $0.00
Disclosure

SEC source: 0001209191-16-155681 · doc4.xml · derivative · entry 2

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2026-12-13

F3 · derivative.exercise_price: The exercise price is the closing price of the Issuer's common stock on December 14, 2016.

F4 · derivative.exercise_date: This option shall vest as follows: 25% on December 14, 2017 and then in quarterly installments over 3 years thereafter.

Read SEC document
December 14, 2016 Filed Dec 16, 2016 22:01 UTC
Levine Mark S.SVP,General Counsel & Sec.
GrantRestricted Stock Units · Derivative 20,000 $0.00 $0.00
Disclosure

SEC source: 0001209191-16-155681 · doc4.xml · derivative · entry 1

Levine Mark S. · CIK 0001617236 · SVP,General Counsel & Sec.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock

F2 · derivative.exercise_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

F2 · derivative.expiration_date: Represents shares issuable upon the vesting of restricted stock units ("RSUs") awarded to the Reporting Person on December 14, 2016. The RSUs vest in 4 equal annual installments beginning on December 14, 2017 and will be fully vested on December 14, 2020, in all cases so long as there has been no break in the Reporting Person's continuous service through such date.

Read SEC document
December 12, 2016 Filed Dec 14, 2016 14:17 UTC OtherWarrant Shares · Derivative 202,634 $0.00 Strike: $5.77 $0.00
Disclosure

SEC source: 0001140361-16-089635 · doc1.xml · derivative · entry 2

Index Venture Associates III Ltd · CIK 0001503683 · 10% owner

Index Venture Associates IV Ltd · CIK 0001447962 · 10% owner

Index Venture Associates V Ltd · CIK 0001611751 · 10% owner

Yucca (Jersey) SLP · CIK 0001591294 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 0

Underlying: Common Shares · 202,634 shares

Expires 2017-03-18

F4 · shares: Composed of 35,376 warrant shares exercised by Index Ventures III (Jersey), L.P., 71,862 warrant shares exercised by Index Ventures III (Delaware), L.P., 1,280 warrant shares exercised by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 warrant shares exercised by Index Ventures IV (Jersey), L.P., 4,631 warrant shares exercised by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 warrant shares exercised by Index Ventures V (Jersey), L.P., 313 warrant shares exercised by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 warrant shares exercised by Yucca (Jersey) SLP.

F2 · derivative.underlying_shares: Composed of 35,376 common shares acquired by Index Ventures III (Jersey), L.P., 71,862 common shares acquired by Index Ventures III (Delaware), L.P., 1,280 common shares acquired by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 common shares acquired by Index Ventures IV (Jersey), L.P., 4,631 common shares acquired by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 common shares acquired by Index Ventures V (Jersey), L.P., 313 common shares acquired by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 common shares acquired by Yucca (Jersey) SLP.

F1 · ownership.nature: Index Venture Associates III Limited is the general partner of Index Ventures III (Jersey), L.P., Index Ventures III (Delaware), L.P., and Index Ventures III Parallel Entrepreneur Fund (Jersey) L.P. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Elian Employee Benefit Services Limited. Index Venture Associates IV Limited is the general partner of Index Ventures IV (Jersey) L.P. and Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. Index Venture Associates V Limited is the general partner of Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. and Index Ventures V (Jersey), L.P.

F3 · ownership.nature: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F5 · ownership.nature: Michele Ollier, Director of the Issuer, is a partner of Medicxi Ventures (Jersey) Limited Succursale de Geneve which provides sub-advisory services to the foregoing funds and Dr. Ollier disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of her proportionate pecuniary interest therein. Francesco De Rubertis, Director of the Issuer, is a partner of Medicxi Ventures (UK) LLP which provides sub-advisory services to the foregoing funds and Dr. De Rubertis disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of his proportionate pecuniary interest therein. Index Venture Associates III Limited, Index Venture Associates IV Limited, Index Venture Associates V Limited and Yucca (Jersey) SLP (collectively, the "Index Entities") are members of a "group" for purposes of Section 13(d) of the Exchange Act.

F6 · ownership.nature: This Statement Form 4 is being filed jointly by the Index Entities. Each of the Index Entities disclaims beneficial ownership held of record by any of the other Index Entities, except to the extent of their respective proportionate pecuniary interest(s) therein.

Read SEC document
December 12, 2016 Filed Dec 14, 2016 14:17 UTC OtherCommon Stock 202,634 $5.77 $1,169,603.45
Disclosure

SEC source: 0001140361-16-089635 · doc1.xml · nonDerivative · entry 1

Index Venture Associates III Ltd · CIK 0001503683 · 10% owner

Index Venture Associates IV Ltd · CIK 0001447962 · 10% owner

Index Venture Associates V Ltd · CIK 0001611751 · 10% owner

Yucca (Jersey) SLP · CIK 0001591294 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,690,906

F2 · shares: Composed of 35,376 common shares acquired by Index Ventures III (Jersey), L.P., 71,862 common shares acquired by Index Ventures III (Delaware), L.P., 1,280 common shares acquired by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 common shares acquired by Index Ventures IV (Jersey), L.P., 4,631 common shares acquired by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 common shares acquired by Index Ventures V (Jersey), L.P., 313 common shares acquired by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 common shares acquired by Yucca (Jersey) SLP.

F3 · balance_after: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F1 · ownership.nature: Index Venture Associates III Limited is the general partner of Index Ventures III (Jersey), L.P., Index Ventures III (Delaware), L.P., and Index Ventures III Parallel Entrepreneur Fund (Jersey) L.P. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Elian Employee Benefit Services Limited. Index Venture Associates IV Limited is the general partner of Index Ventures IV (Jersey) L.P. and Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. Index Venture Associates V Limited is the general partner of Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. and Index Ventures V (Jersey), L.P.

F3 · ownership.nature: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F5 · ownership.nature: Michele Ollier, Director of the Issuer, is a partner of Medicxi Ventures (Jersey) Limited Succursale de Geneve which provides sub-advisory services to the foregoing funds and Dr. Ollier disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of her proportionate pecuniary interest therein. Francesco De Rubertis, Director of the Issuer, is a partner of Medicxi Ventures (UK) LLP which provides sub-advisory services to the foregoing funds and Dr. De Rubertis disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of his proportionate pecuniary interest therein. Index Venture Associates III Limited, Index Venture Associates IV Limited, Index Venture Associates V Limited and Yucca (Jersey) SLP (collectively, the "Index Entities") are members of a "group" for purposes of Section 13(d) of the Exchange Act.

F6 · ownership.nature: This Statement Form 4 is being filed jointly by the Index Entities. Each of the Index Entities disclaims beneficial ownership held of record by any of the other Index Entities, except to the extent of their respective proportionate pecuniary interest(s) therein.

Read SEC document
December 12, 2016 Filed Dec 14, 2016 14:24 UTC
Ollier MicheleDirector · 10% owner
OtherWarrant Shares · Derivative 202,634 $0.00 Strike: $5.77 $0.00
Disclosure

SEC source: 0001140361-16-089642 · doc1.xml · derivative · entry 2

Ollier Michele · CIK 0001503685 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 0

Underlying: Common Shares · 202,634 shares

Expires 2017-03-18

F4 · shares: Composed of 35,376 warrant shares exercised by Index Ventures III (Jersey), L.P., 71,862 warrant shares exercised by Index Ventures III (Delaware), L.P., 1,280 warrant shares exercised by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 warrant shares exercised by Index Ventures IV (Jersey), L.P., 4,631 warrant shares exercised by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 warrant shares exercised by Index Ventures V (Jersey), L.P., 313 warrant shares exercised by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 warrant shares exercised by Yucca (Jersey) SLP.

F2 · derivative.underlying_shares: Composed of 35,376 common shares acquired by Index Ventures III (Jersey), L.P., 71,862 common shares acquired by Index Ventures III (Delaware), L.P., 1,280 common shares acquired by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 common shares acquired by Index Ventures IV (Jersey), L.P., 4,631 common shares acquired by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 common shares acquired by Index Ventures V (Jersey), L.P., 313 common shares acquired by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 common shares acquired by Yucca (Jersey) SLP.

F1 · ownership.nature: Index Venture Associates III Limited is the general partner of Index Ventures III (Jersey), L.P., Index Ventures III (Delaware), L.P., and Index Ventures III Parallel Entrepreneur Fund (Jersey)L.P. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Elian Employee Benefit Services Limited. Index Venture Associates IV Limited is the general partner of Index Ventures IV (Jersey) L.P. and Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. Index Venture Associates V Limited is the general partner of Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. and Index Ventures V (Jersey), L.P.

F3 · ownership.nature: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F5 · ownership.nature: Michele Ollier, Director of the Issuer, is a partner of Medicxi Ventures (Jersey) Limited Succursale de Geneve which provides sub-advisory services to the foregoing funds and Dr. Ollier disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of her proportionate pecuniary interest therein. Francesco De Rubertis, Director of the Issuer, is a partner of Medicxi Ventures (UK) LLP which provides sub-advisory services to the foregoing funds and Dr. De Rubertis disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of his proportionate pecuniary interest therein. Index Venture Associates III Limited, Index Venture Associates IV Limited, Index Venture Associates V Limited and Yucca (Jersey) SLP (collectively, the "Index Entities") are members of a "group" for purposes of Section 13(d) of the Exchange Act.

Read SEC document
December 12, 2016 Filed Dec 14, 2016 14:24 UTC
Ollier MicheleDirector · 10% owner
OtherCommon Stock 202,634 $5.77 $1,169,603.45
Disclosure

SEC source: 0001140361-16-089642 · doc1.xml · nonDerivative · entry 1

Ollier Michele · CIK 0001503685 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,690,906

F2 · shares: Composed of 35,376 common shares acquired by Index Ventures III (Jersey), L.P., 71,862 common shares acquired by Index Ventures III (Delaware), L.P., 1,280 common shares acquired by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 common shares acquired by Index Ventures IV (Jersey), L.P., 4,631 common shares acquired by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 common shares acquired by Index Ventures V (Jersey), L.P., 313 common shares acquired by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 common shares acquired by Yucca (Jersey) SLP.

F3 · balance_after: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F1 · ownership.nature: Index Venture Associates III Limited is the general partner of Index Ventures III (Jersey), L.P., Index Ventures III (Delaware), L.P., and Index Ventures III Parallel Entrepreneur Fund (Jersey)L.P. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Elian Employee Benefit Services Limited. Index Venture Associates IV Limited is the general partner of Index Ventures IV (Jersey) L.P. and Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. Index Venture Associates V Limited is the general partner of Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. and Index Ventures V (Jersey), L.P.

F3 · ownership.nature: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F5 · ownership.nature: Michele Ollier, Director of the Issuer, is a partner of Medicxi Ventures (Jersey) Limited Succursale de Geneve which provides sub-advisory services to the foregoing funds and Dr. Ollier disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of her proportionate pecuniary interest therein. Francesco De Rubertis, Director of the Issuer, is a partner of Medicxi Ventures (UK) LLP which provides sub-advisory services to the foregoing funds and Dr. De Rubertis disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of his proportionate pecuniary interest therein. Index Venture Associates III Limited, Index Venture Associates IV Limited, Index Venture Associates V Limited and Yucca (Jersey) SLP (collectively, the "Index Entities") are members of a "group" for purposes of Section 13(d) of the Exchange Act.

Read SEC document
December 12, 2016 Filed Dec 14, 2016 19:22 UTC
De Rubertis FrancescoDirector · 10% owner
OtherWarrant Shares · Derivative 202,634 $0.00 Strike: $5.77 $0.00
Disclosure

SEC source: 0001140361-16-089639 · doc1.xml · derivative · entry 2

De Rubertis Francesco · CIK 0001601521 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 0

Underlying: Common Shares · 202,634 shares

Expires 2017-03-18

F4 · shares: Composed of 35,376 warrant shares exercised by Index Ventures III (Jersey), L.P., 71,862 warrant shares exercised by Index Ventures III (Delaware), L.P., 1,280 warrant shares exercised by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 warrant shares exercised by Index Ventures IV (Jersey), L.P., 4,631 warrant shares exercised by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 warrant shares exercised by Index Ventures V (Jersey), L.P., 313 warrant shares exercised by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 warrant shares exercised by Yucca (Jersey) SLP.

F2 · derivative.underlying_shares: Composed of 35,376 common shares acquired by Index Ventures III (Jersey), L.P., 71,862 common shares acquired by Index Ventures III (Delaware), L.P., 1,280 common shares acquired by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 common shares acquired by Index Ventures IV (Jersey), L.P., 4,631 common shares acquired by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 common shares acquired by Index Ventures V (Jersey), L.P., 313 common shares acquired by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 common shares acquired by Yucca (Jersey) SLP.

F1 · ownership.nature: Index Venture Associates III Limited is the general partner of Index Ventures III (Jersey), L.P., Index Ventures III (Delaware), L.P., and Index Ventures III Parallel Entrepreneur Fund (Jersey)L.P. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Elian Employee Benefit Services Limited. Index Venture Associates IV Limited is the general partner of Index Ventures IV (Jersey) L.P. and Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. Index Venture Associates V Limited is the general partner of Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. and Index Ventures V (Jersey), L.P.

F3 · ownership.nature: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F5 · ownership.nature: Michele Ollier, Director of the Issuer, is a partner of Medicxi Ventures (Jersey) Limited Succursale de Geneve which provides sub-advisory services to the foregoing funds and Dr. Ollier disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of her proportionate pecuniary interest therein. Francesco De Rubertis, Director of the Issuer, is a partner of Medicxi Ventures (UK) LLP which provides sub-advisory services to the foregoing funds and Dr. De Rubertis disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of his proportionate pecuniary interest therein. Index Venture Associates III Limited, Index Venture Associates IV Limited, Index Venture Associates V Limited and Yucca (Jersey) SLP (collectively, the "Index Entities") are members of a "group" for purposes of Section 13(d) of the Exchange Act.

Read SEC document
December 12, 2016 Filed Dec 14, 2016 19:22 UTC
De Rubertis FrancescoDirector · 10% owner
OtherCommon Stock 202,634 $5.77 $1,169,603.45
Disclosure

SEC source: 0001140361-16-089639 · doc1.xml · nonDerivative · entry 1

De Rubertis Francesco · CIK 0001601521 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,690,906

F2 · shares: Composed of 35,376 common shares acquired by Index Ventures III (Jersey), L.P., 71,862 common shares acquired by Index Ventures III (Delaware), L.P., 1,280 common shares acquired by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 48,790 common shares acquired by Index Ventures IV (Jersey), L.P., 4,631 common shares acquired by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 38,584 common shares acquired by Index Ventures V (Jersey), L.P., 313 common shares acquired by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 1,798 common shares acquired by Yucca (Jersey) SLP.

F3 · balance_after: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F1 · ownership.nature: Index Venture Associates III Limited is the general partner of Index Ventures III (Jersey), L.P., Index Ventures III (Delaware), L.P., and Index Ventures III Parallel Entrepreneur Fund (Jersey)L.P. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Elian Employee Benefit Services Limited. Index Venture Associates IV Limited is the general partner of Index Ventures IV (Jersey) L.P. and Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. Index Venture Associates V Limited is the general partner of Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. and Index Ventures V (Jersey), L.P.

F3 · ownership.nature: Composed of 813,095 common shares held by Index Ventures III (Jersey), L.P., 1,651,714 common shares held by Index Ventures III (Delaware), L.P., 29,424 common shares held by Index Ventures III Parallel Entrepreneur Fund (Jersey), L.P., 1,129,474 common shares held by Index Ventures IV (Jersey), L.P., 107,210 common shares held by Index Ventures IV Parallel Entrepreneur Fund (Jersey), L.P., 893,199 common shares held by Index Ventures V (Jersey), L.P., 7,238 common shares held by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P., and 59,552 common shares held by Yucca (Jersey) SLP.

F5 · ownership.nature: Michele Ollier, Director of the Issuer, is a partner of Medicxi Ventures (Jersey) Limited Succursale de Geneve which provides sub-advisory services to the foregoing funds and Dr. Ollier disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of her proportionate pecuniary interest therein. Francesco De Rubertis, Director of the Issuer, is a partner of Medicxi Ventures (UK) LLP which provides sub-advisory services to the foregoing funds and Dr. De Rubertis disclaims beneficial ownership of all such shares held by the foregoing funds, except to the extent of his proportionate pecuniary interest therein. Index Venture Associates III Limited, Index Venture Associates IV Limited, Index Venture Associates V Limited and Yucca (Jersey) SLP (collectively, the "Index Entities") are members of a "group" for purposes of Section 13(d) of the Exchange Act.

Read SEC document
March 18, 2015 Filed Feb 12, 2016 16:54 UTC PurchaseCommon Stock 607,903 $4.93 $2,996,961.79
Disclosure

SEC source: 0000904454-16-000987 · edgar.xml · nonDerivative · entry 1

JOHNSON & JOHNSON · CIK 0000200406 · 10% owner

Johnson & Johnson Innovation - JJDC, Inc. · CIK 0000924020 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Johnson & Johnson Innovation - JJDC, Inc.

Disclosed balance after: 3,892,256

F1 · ownership.nature: The securities reported as being indirectly beneficially owned by the Reporting Person are directly beneficially owned by Johnson & Johnson Innovation - JJDC, Inc., a wholly-owed subsidiary of the Reporting Person.

Read SEC document
March 13, 2015 Filed Mar 17, 2015 22:43 UTC PurchaseWarrants (right to buy) · Derivative 607,903 $0.13 Strike: $5.77 $75,987.88
Disclosure

SEC source: 0001144204-15-016825 · v404607_4.xml · derivative · entry 2

JOHNSON & JOHNSON · CIK 0000200406 · 10% owner

Johnson & Johnson Innovation - JJDC, Inc. · CIK 0000924020 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Johnson & Johnson Innovation- JJDC, Inc.

Disclosed balance after: 607,903

Underlying: Common Stock · 607,903 shares

Expires 2017-03-18

F1 · date: The transaction is subject to customary closing conditions and is expected to close on or about 03/18/2015.

F1 · derivative.exercise_date: The transaction is subject to customary closing conditions and is expected to close on or about 03/18/2015.

F3 · ownership.nature: The securities reported as being indirectly beneficially owned by the designated Reporting Person are directly beneficially owned by Johnson & Johnson Innovation - JJDC, Inc., a wholly-owned subsidiary of the designated Reporting Person (formerly known as Johnson & Johnson Development Corporation).

Read SEC document
March 13, 2015 Filed Mar 17, 2015 22:43 UTC PurchaseCommon Stock 607,903 $4.81 $2,924,013.43
Disclosure

SEC source: 0001144204-15-016825 · v404607_4.xml · nonDerivative · entry 1

JOHNSON & JOHNSON · CIK 0000200406 · 10% owner

Johnson & Johnson Innovation - JJDC, Inc. · CIK 0000924020 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Johnson & Johnson Innovation - JJDC, Inc.

Disclosed balance after: 4,500,159

F1 · date: The transaction is subject to customary closing conditions and is expected to close on or about 03/18/2015.

F2 · balance_after: Consists of 3,892,256 shares of Common Stock and 607,903 shares of Common Stock underlying immediately exercisable warrants.

F3 · ownership.nature: The securities reported as being indirectly beneficially owned by the designated Reporting Person are directly beneficially owned by Johnson & Johnson Innovation - JJDC, Inc., a wholly-owned subsidiary of the designated Reporting Person (formerly known as Johnson & Johnson Development Corporation).

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.