MPLT

SEC source: 0001789970-26-000016 · form4-09182026_040901.xml · nonDerivative · entry 1

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 137,044

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 29, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $11.38 to $12.17 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021238-26-000012 · form4-08192026_060813.xml · derivative · entry 2

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,455

Underlying: Voting Common Stock · 24,455 shares

Expires 2036-08-16

F3 · derivative.exercise_date: 1/4th of the total shares underlying the option shall vest on July 1, 2027, and 1/48th of the total shares shall vest each month thereafter on the same day of the month, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0002021238-26-000012 · form4-08192026_060813.xml · nonDerivative · entry 1

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 180,926

F1 · shares: Represents a restricted stock unit ("RSU") award. 1/4th of the RSUs shall vest on July 1, 2027, and 1/16th of the RSUs shall vest on each subsequent October 1, January 1, April 1 and July 1 thereafter, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0002021233-26-000014 · form4-08192026_060804.xml · derivative · entry 2

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,240

Underlying: Voting Common Stock · 54,240 shares

Expires 2036-08-16

F3 · derivative.exercise_date: 1/4th of the total shares underlying the option shall vest on July 1, 2027, and 1/48th of the total shares shall vest each month thereafter on the same day of the month, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0002021233-26-000014 · form4-08192026_060804.xml · nonDerivative · entry 1

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 312,261

F1 · shares: Represents a restricted stock unit ("RSU") award. 1/4th of the RSUs shall vest on July 1, 2027, and 1/16th of the RSUs shall vest on each subsequent October 1, January 1, April 1 and July 1 thereafter, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0001658918-26-000016 · form4-08192026_060801.xml · derivative · entry 3

Kroeger Christopher A. · CIK 0001658918 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 93,955

Underlying: Voting Common Stock · 93,955 shares

Expires 2036-08-16

F4 · derivative.exercise_date: 1/4th of the total shares underlying the option shall vest on July 1, 2027, and 1/48th of the total shares shall vest each month thereafter on the same day of the month, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001658918-26-000016 · form4-08192026_060801.xml · nonDerivative · entry 1

Kroeger Christopher A. · CIK 0001658918 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,269,600

F1 · shares: Represents a restricted stock unit ("RSU") award. 1/4th of the RSUs shall vest on July 1, 2027, and 1/16th of the RSUs shall vest on each subsequent October 1, January 1, April 1 and July 1 thereafter, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0001709954-26-000012 · form4-08192026_060811.xml · derivative · entry 4

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,813

Underlying: Voting Common Stock · 2,813 shares

Expires 2036-08-16

F5 · derivative.exercise_date: The option share vest in 24 equal monthly installments commencing on August 1, 2026, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001709954-26-000012 · form4-08192026_060811.xml · derivative · entry 3

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,455

Underlying: Voting Common Stock · 24,455 shares

Expires 2036-08-16

F4 · derivative.exercise_date: 1/4th of the total shares underlying the option shall vest on July 1, 2027, and 1/48th of the total shares shall vest each month thereafter on the same day of the month, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001709954-26-000012 · form4-08192026_060811.xml · nonDerivative · entry 2

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 152,482

F3 · shares: Represents an RSU award. The RSUs shall vest in 8 equal quarterly installments commencing on October 1, 2026, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0001709954-26-000012 · form4-08192026_060811.xml · nonDerivative · entry 1

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,260

F1 · shares: Represents a restricted stock unit ("RSU") award. 1/4th of the RSUs shall vest on July 1, 2027, and 1/16th of the RSUs shall vest on each subsequent October 1, January 1, April 1 and July 1 thereafter, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0001728746-26-000016 · form4-08192026_060808.xml · derivative · entry 2

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,395

Underlying: Voting Common Stock · 31,395 shares

Expires 2036-08-16

F3 · derivative.exercise_date: 1/4th of the total shares underlying the option shall vest on July 1, 2027, and 1/48th of the total shares shall vest each month thereafter on the same day of the month, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001728746-26-000016 · form4-08192026_060808.xml · nonDerivative · entry 1

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 210,110

F1 · shares: Represents a restricted stock unit ("RSU") award. 1/4th of the RSUs shall vest on July 1, 2027, and 1/16th of the RSUs shall vest on each subsequent October 1, January 1, April 1 and July 1 thereafter, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0001789970-26-000014 · form4-08192026_060806.xml · derivative · entry 2

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,395

Underlying: Voting Common Stock · 31,395 shares

Expires 2036-08-16

F3 · derivative.exercise_date: 1/4th of the total shares underlying the option shall vest on July 1, 2027, and 1/48th of the total shares shall vest each month thereafter on the same day of the month, subject to the Reporting Person's continued service through each vesting date.

SEC source: 0001789970-26-000014 · form4-08192026_060806.xml · nonDerivative · entry 1

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,553

F1 · shares: Represents a restricted stock unit ("RSU") award. 1/4th of the RSUs shall vest on July 1, 2027, and 1/16th of the RSUs shall vest on each subsequent October 1, January 1, April 1 and July 1 thereafter, subject to the Reporting Person's continued service through each vesting date.

F2 · price: Each RSU represents a contingent right to receive one share of voting common stock of the Issuer.

SEC source: 0001900201-26-000005 · form4-08182026_100832.xml · derivative · entry 2

Catalyst4, Inc. · CIK 0001900201 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 2,928,686

Underlying: Voting Common Stock · 2,928,686 shares

Expires not disclosed

F2 · derivative.exercise_date: The warrant is immediately exercisable, however, the warrant may not be exercised if the aggregate number of shares of voting common stock beneficially owned by the reporting person immediately following such exercise would exceed 49.99%.

F3 · derivative.expiration_date: The warrants will not expire until exercised in full.

F1 · ownership.nature: The shares are held of record by Catalyst4, Inc. ("Catalyst4"). As the members of the board of directors of Catalyst4, Robert Brown, Ekemini Riley and Mark Vorsatz share voting and dispositive power with respect to the shares held by Catalyst4. Each of Mr. Brown, Ms. Riley and Mr. Vorsatz disclaims beneficial ownership of the shares reported herein.

SEC source: 0001900201-26-000005 · form4-08182026_100832.xml · nonDerivative · entry 1

Catalyst4, Inc. · CIK 0001900201 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 25,306,689

F1 · ownership.nature: The shares are held of record by Catalyst4, Inc. ("Catalyst4"). As the members of the board of directors of Catalyst4, Robert Brown, Ekemini Riley and Mark Vorsatz share voting and dispositive power with respect to the shares held by Catalyst4. Each of Mr. Brown, Ms. Riley and Mr. Vorsatz disclaims beneficial ownership of the shares reported herein.

SEC source: 0001728746-26-000014 · form4-08052026_120851.xml · nonDerivative · entry 1

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 202,380

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 29, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.12 to $12.99 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001900201-26-000003 · form4-07302026_100713.xml · nonDerivative · entry 4

Catalyst4, Inc. · CIK 0001900201 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 20,906,689

F2 · ownership.nature: The shares are held of record by Catalyst4, Inc. ("Catalyst4"). As the members of the board of directors of Catalyst4, Robert Brown, Ekemini Riley and Mark Vorsatz share voting and dispositive power with respect to the shares held by Catalyst4. Each of Mr. Brown, Ms. Riley and Mr. Vorsatz disclaims beneficial ownership of the shares reported herein.

SEC source: 0001900201-26-000003 · form4-07302026_100713.xml · nonDerivative · entry 3

Catalyst4, Inc. · CIK 0001900201 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 19,906,689

F2 · ownership.nature: The shares are held of record by Catalyst4, Inc. ("Catalyst4"). As the members of the board of directors of Catalyst4, Robert Brown, Ekemini Riley and Mark Vorsatz share voting and dispositive power with respect to the shares held by Catalyst4. Each of Mr. Brown, Ms. Riley and Mr. Vorsatz disclaims beneficial ownership of the shares reported herein.

SEC source: 0001696923-26-000007 · form4-07292026_010736.xml · nonDerivative · entry 1

Cox Troy · CIK 0001696923 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By trust

Disclosed balance after: 15,620

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.305 to $9.78 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

F2 · ownership.nature: The shares are held by the Troy M Cox & Adeo C Alday JT Revocable Trust dtd 5/28/25, of which the Reporting Person is co-trustee with his spouse and has voting and dispositive power.

SEC source: 0001900201-26-000003 · form4-07302026_100713.xml · nonDerivative · entry 2

Catalyst4, Inc. · CIK 0001900201 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 19,903,689

F3 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $11.31 to $12.00, inclusive.

F2 · ownership.nature: The shares are held of record by Catalyst4, Inc. ("Catalyst4"). As the members of the board of directors of Catalyst4, Robert Brown, Ekemini Riley and Mark Vorsatz share voting and dispositive power with respect to the shares held by Catalyst4. Each of Mr. Brown, Ms. Riley and Mr. Vorsatz disclaims beneficial ownership of the shares reported herein.

SEC source: 0001900201-26-000003 · form4-07302026_100713.xml · nonDerivative · entry 1

Catalyst4, Inc. · CIK 0001900201 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 19,838,552

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $10.295 to $11.28, inclusive. The reporting person undertakes to provide the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in footnotes (1) and (3) to this Form 4.

F2 · ownership.nature: The shares are held of record by Catalyst4, Inc. ("Catalyst4"). As the members of the board of directors of Catalyst4, Robert Brown, Ekemini Riley and Mark Vorsatz share voting and dispositive power with respect to the shares held by Catalyst4. Each of Mr. Brown, Ms. Riley and Mr. Vorsatz disclaims beneficial ownership of the shares reported herein.

SEC source: 0002021233-26-000012 · form4-07182026_010714.xml · nonDerivative · entry 9

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 298,901

F4 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.49 to $37.925 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001658918-26-000014 · form4-07182026_010744.xml · nonDerivative · entry 7

Kroeger Christopher A. · CIK 0001658918 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,246,455

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.49 to $37.925 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001728746-26-000012 · form4-07182026_010728.xml · nonDerivative · entry 7

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 224,462

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.49 to $37.925 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001789970-26-000012 · form4-07182026_010724.xml · nonDerivative · entry 7

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 145,823

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.49 to $37.925 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021238-26-000010 · form4-07202026_060701.xml · nonDerivative · entry 7

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 174,906

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 24, 2025.

F6 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 24, 2025.

SEC source: 0002021238-26-000010 · form4-07202026_060701.xml · nonDerivative · entry 6

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 175,106

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 24, 2025.

F6 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 24, 2025.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.36 to $38.21 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021238-26-000010 · form4-07202026_060701.xml · nonDerivative · entry 5

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 189,246

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 24, 2025.

F6 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 24, 2025.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.36 to $37.335 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001709954-26-000010 · form4-07202026_060704.xml · nonDerivative · entry 7

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 144,240

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 26, 2025.

F6 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 26, 2025.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.00 to $38.37 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001709954-26-000010 · form4-07202026_060704.xml · nonDerivative · entry 6

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,140

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 26, 2025.

F6 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 26, 2025.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.00 to $37.99 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001709954-26-000010 · form4-07202026_060704.xml · nonDerivative · entry 5

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 162,109

F6 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 26, 2025.

F6 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 26, 2025.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.91 to $36.89 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021233-26-000012 · form4-07182026_010714.xml · nonDerivative · entry 8

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,557

F4 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

SEC source: 0002021233-26-000012 · form4-07182026_010714.xml · nonDerivative · entry 7

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,576

F4 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.9082 to $37.89 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021233-26-000012 · form4-07182026_010714.xml · nonDerivative · entry 6

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 308,441

F4 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.9075 to $36.9013 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001658918-26-000014 · form4-07182026_010744.xml · nonDerivative · entry 6

Kroeger Christopher A. · CIK 0001658918 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,263,234

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

SEC source: 0001658918-26-000014 · form4-07182026_010744.xml · nonDerivative · entry 5

Kroeger Christopher A. · CIK 0001658918 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,263,326

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.9082 to $37.89 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001658918-26-000014 · form4-07182026_010744.xml · nonDerivative · entry 4

Kroeger Christopher A. · CIK 0001658918 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,291,417

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.9075 to $36.9013 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001728746-26-000012 · form4-07182026_010728.xml · nonDerivative · entry 6

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 226,539

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

SEC source: 0001728746-26-000012 · form4-07182026_010728.xml · nonDerivative · entry 5

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 226,551

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.9082 to $37.89 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001728746-26-000012 · form4-07182026_010728.xml · nonDerivative · entry 4

Lillie James Woodruff · CIK 0001728746 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 230,077

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.9075 to $36.9013 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001789970-26-000012 · form4-07182026_010724.xml · nonDerivative · entry 6

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 146,953

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

SEC source: 0001789970-26-000012 · form4-07182026_010724.xml · nonDerivative · entry 5

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 146,964

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.9082 to $37.89 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001789970-26-000012 · form4-07182026_010724.xml · nonDerivative · entry 4

Hanson Kristopher · CIK 0001789970 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,295

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $35.9075 to $36.9013 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021238-26-000010 · form4-07202026_060701.xml · nonDerivative · entry 4

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 192,079

F1 · kind: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.26 to $37.70 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021238-26-000010 · form4-07202026_060701.xml · nonDerivative · entry 3

Kreitzer Anatol · CIK 0002021238 · Chief Discovery Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 193,671

F1 · kind: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.12 to $37.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001709954-26-000010 · form4-07202026_060704.xml · nonDerivative · entry 4

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 162,709

F1 · kind: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.26 to $37.70 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001709954-26-000010 · form4-07202026_060704.xml · nonDerivative · entry 3

GILLIS JONATHAN · CIK 0001709954 · CAO and Interim CFO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 164,185

F1 · kind: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F1 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $36.12 to $37.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002021233-26-000012 · form4-07182026_010714.xml · nonDerivative · entry 5

Foff Erin Pennock · CIK 0002021233 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 317,604

F4 · shares: Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting of the restricted stock units. This sale is mandated by the Issuer's election under its equity incentive plans to require the satisfaction of minimum statutory tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary sale by the Reporting Person.