LXEO

SEC source: 0001415889-25-001283 · form4-01102025_040101.xml · derivative · entry 2

Adler Eric · CIK 0001994972 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,500

Underlying: Common Stock · 87,500 shares

Expires 2035-01-06

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on January 7, 2026, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-25-001283 · form4-01102025_040101.xml · nonDerivative · entry 1

Adler Eric · CIK 0001994972 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,625

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2026, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

F2 · balance_after: The reported securities are RSUs.

SEC source: 0001415889-24-029143 · form4-12122024_051206.xml · derivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 118,655

Underlying: Common Stock · 2,500 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F4 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-029143 · form4-12122024_051206.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.98 to $8.54. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-029143 · form4-12122024_051206.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 123,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001415889-24-027746 · form4-11262024_051101.xml · nonDerivative · entry 1

CHOLMONDELEY PAULA H · CIK 0001193675 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,627

F1 · balance_after: 15,627 of the shares are subject to vesting and vest at the following rate: 1/48th of the shares vested or vest in monthly installments commencing on December 1, 2021, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-026739 · form4-11132024_101138.xml · derivative · entry 1

Tanguler Tolga · CIK 0001849458 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2034-11-10

F1 · derivative.exercise_date: The shares subject to the option shall vest and become exercisable in equal annual installments over a three year period such that the option is fully vested on the third anniversary of the date of grant, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-026737 · form4-11132024_101126.xml · derivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 121,155

Underlying: Common Stock · 2,500 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F4 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-026737 · form4-11132024_101126.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.49 to $8.00. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-026737 · form4-11132024_101126.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 123,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001415889-24-025110 · form4-10152024_011001.xml · derivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 123,655

Underlying: Common Stock · 5,000 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F4 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-025110 · form4-10152024_011001.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $7.99 to $8.3591. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-025110 · form4-10152024_011001.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001415889-24-023233 · form4-09112024_090900.xml · derivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 128,655

Underlying: Common Stock · 5,000 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F4 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-023233 · form4-09112024_090900.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $10.37 to $10.925. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-023233 · form4-09112024_090900.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001415889-24-021245 · form4-08132024_100801.xml · derivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 133,655

Underlying: Common Stock · 5,000 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F4 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-021245 · form4-08132024_100801.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $11.05 to $11.94. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-021245 · form4-08132024_100801.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001415889-24-019526 · form4-07122024_040703.xml · nonDerivative · entry 5

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F5 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-019526 · form4-07122024_040703.xml · nonDerivative · entry 4

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 120,795

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F4 · price: This transaction was executed in multiple trades at prices ranging from $16.7476 to $17.4703. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-019526 · form4-07122024_040703.xml · derivative · entry 6

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 138,655

Underlying: Common Stock · 5,000 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F6 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-019526 · form4-07122024_040703.xml · nonDerivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 148,726

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F3 · price: This transaction was executed in multiple trades at prices ranging from $16.83 to $16.95. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-019526 · form4-07122024_040703.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 152,073

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $15.83 to $16.825. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-019526 · form4-07122024_040703.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 175,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001415889-24-019380 · form4-07082024_100700.xml · derivative · entry 1

Van Hauwermeiren Timothy · CIK 0001816206 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2034-07-04

F1 · derivative.exercise_date: The shares subject to the option shall vest and become exercisable in equal annual installments over a three year period such that the option is fully vested on the third anniversary of the date of grant, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-018348 · form4-06272024_090634.xml · derivative · entry 1

Altschuler Steven · CIK 0001458116 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2034-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of June 25, 2025, or the date of the Issuer's next annual stockholders meeting, subject to the Reporting Person's continuous service on such date.

SEC source: 0001415889-24-018347 · form4-06272024_090647.xml · derivative · entry 1

DIAZ REINALDO M · CIK 0001250086 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2034-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of June 25, 2025, or the date of the Issuer's next annual stockholders meeting, subject to the Reporting Person's continuous service on such date.

SEC source: 0001415889-24-018346 · form4-06272024_090651.xml · derivative · entry 1

CHOLMONDELEY PAULA H · CIK 0001193675 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2034-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of June 25, 2025, or the date of the Issuer's next annual stockholders meeting, subject to the Reporting Person's continuous service on such date.

SEC source: 0001415889-24-018343 · form4-06272024_090603.xml · derivative · entry 1

Agger Mette Kirstine · CIK 0001722234 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2034-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of June 25, 2025, or the date of the Issuer's next annual stockholders meeting, subject to the Reporting Person's continuous service on such date.

SEC source: 0001415889-24-018349 · form4-06272024_090642.xml · derivative · entry 1

COOPERSTONE BRENDA · CIK 0001931514 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2034-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of June 25, 2025, or the date of the Issuer's next annual stockholders meeting, subject to the Reporting Person's continuous service on such date.

SEC source: 0000950170-24-073371 · ownership.xml · derivative · entry 2

Otero Jose Manuel · CIK 0002024096 · Chief Technical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 187,500

Underlying: Common Stock · 187,500 shares

Expires 2034-06-11

F2 · derivative.exercise_date: 25% of the shares underlying the option shall vest on May 20, 2025, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0000950170-24-073371 · ownership.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Technical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,250

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on August 15, 2025, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

SEC source: 0001415889-24-016518 · form4-06122024_050602.xml · derivative · entry 4

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,655

Underlying: Common Stock · 5,000 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F5 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001415889-24-016518 · form4-06122024_050602.xml · nonDerivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 170,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F3 · price: This transaction was executed in multiple trades at prices ranging from $17.78 to $18.67. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F4 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0001415889-24-016518 · form4-06122024_050602.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 172,733

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $16.80 to $17.76. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0001415889-24-016518 · form4-06122024_050602.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 175,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0000950170-24-059506 · ownership.xml · derivative · entry 3

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 148,655

Underlying: Common Stock · 5,000 shares

Expires 2031-02-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 25% of the shares underlying the option vested on November 21, 2021, and 1/48th of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0000950170-24-059506 · ownership.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 170,695

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

F2 · price: This transaction was executed in multiple trades at prices ranging from $12.98 to $13.40. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 43,750 restricted stock units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0000950170-24-059506 · ownership.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 175,695

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercises and sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2023.

SEC source: 0001209191-24-002930 · doc4.xml · derivative · entry 1

DIAZ REINALDO M · CIK 0001250086 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2034-02-01

F1 · derivative.exercise_date: 25% of the shares underlying the option shall vest and become exercisable on November 2, 2024, and 1/48th of the shares underlying the option shall vest in equal monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001209191-24-002929 · doc4.xml · derivative · entry 1

Agger Mette Kirstine · CIK 0001722234 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,000

Underlying: Common Stock · 36,000 shares

Expires 2034-02-01

F1 · derivative.exercise_date: 25% of the shares underlying the option shall vest and become exercisable on November 2, 2024, and 1/48th of the shares underlying the option shall vest in equal monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001209191-24-002928 · doc4.xml · derivative · entry 2

Adler Eric · CIK 0001994972 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 161,250

Underlying: Common Stock · 161,250 shares

Expires 2034-02-01

F2 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on February 2, 2025, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001209191-24-002928 · doc4.xml · nonDerivative · entry 1

Adler Eric · CIK 0001994972 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,875

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2025, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

SEC source: 0000950170-24-003466 · ownership.xml · derivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 262,500

Underlying: Common Stock · 262,500 shares

Expires 2034-01-04

F3 · derivative.exercise_date: 25% of the shares underlying the option shall vest on January 5, 2025, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0000950170-24-003466 · ownership.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 170,695

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2025, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

F2 · balance_after: Total represents 126,945 shares of Common Stock and 43,750 RSUs.

SEC source: 0000950170-24-003464 · ownership.xml · derivative · entry 2

Robertson Jenny · CIK 0001995009 · Chief Legal and Admin Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 142,500

Underlying: Common Stock · 142,500 shares

Expires 2034-01-04

F2 · derivative.exercise_date: 25% of the shares underlying the option shall vest on January 5, 2025, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0000950170-24-003464 · ownership.xml · nonDerivative · entry 1

Robertson Jenny · CIK 0001995009 · Chief Legal and Admin Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,750

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2025, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

SEC source: 0001209191-23-054913 · doc4.xml · derivative · entry 5

Omega Fund VI, L.P. · CIK 0001757917 · 10% owner

Omega Fund VI GP, L.P. · CIK 0001826592 · 10% owner

Omega Fund VI GP Manager, Ltd. · CIK 0001826584 · 10% owner

Stampacchia Otello · CIK 0001361712 · 10% owner

Nessi Claudio · CIK 0001722050 · 10% owner

Paster Anne-Mari · CIK 0001652863 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 287,213 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series B convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-9.106601 basis, which reflects an anti-dilution adjustment to the conversion ratio pursuant to a provision of the Series B convertible preferred stock based on the pricing of the initial public offering (as described in the Reporting Person's Form 3). The shares had no expiration date.

F2 · price: Upon the closing of the Issuer's initial public offering, each share of Series B convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-9.106601 basis, which reflects an anti-dilution adjustment to the conversion ratio pursuant to a provision of the Series B convertible preferred stock based on the pricing of the initial public offering (as described in the Reporting Person's Form 3). The shares had no expiration date.

F2 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series B convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-9.106601 basis, which reflects an anti-dilution adjustment to the conversion ratio pursuant to a provision of the Series B convertible preferred stock based on the pricing of the initial public offering (as described in the Reporting Person's Form 3). The shares had no expiration date.

F2 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series B convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-9.106601 basis, which reflects an anti-dilution adjustment to the conversion ratio pursuant to a provision of the Series B convertible preferred stock based on the pricing of the initial public offering (as described in the Reporting Person's Form 3). The shares had no expiration date.

SEC source: 0001209191-23-054913 · doc4.xml · derivative · entry 4

Omega Fund VI, L.P. · CIK 0001757917 · 10% owner

Omega Fund VI GP, L.P. · CIK 0001826592 · 10% owner

Omega Fund VI GP Manager, Ltd. · CIK 0001826584 · 10% owner

Stampacchia Otello · CIK 0001361712 · 10% owner

Nessi Claudio · CIK 0001722050 · 10% owner

Paster Anne-Mari · CIK 0001652863 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,415,865 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Upon the closing of the Issuer's initial public offering, each share of Series A convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-10.594230 basis. The shares had no expiration date.

F1 · price: Upon the closing of the Issuer's initial public offering, each share of Series A convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-10.594230 basis. The shares had no expiration date.

F1 · derivative.exercise_date: Upon the closing of the Issuer's initial public offering, each share of Series A convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-10.594230 basis. The shares had no expiration date.

F1 · derivative.expiration_date: Upon the closing of the Issuer's initial public offering, each share of Series A convertible preferred stock automatically converted into shares of the Issuer's common stock on a one-for-10.594230 basis. The shares had no expiration date.