LXEO

SEC source: 0002024096-26-000015 · form4-09282026_050904.xml · derivative · entry 2

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,750

Underlying: Common Stock · 54,750 shares

Expires 2036-09-23

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on September 24, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0002109299-26-000009 · form4-09282026_050906.xml · derivative · entry 2

Bhalla Narinder Pal · CIK 0002109299 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,750

Underlying: Common Stock · 54,750 shares

Expires 2036-09-23

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on September 24, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0002083206-26-000009 · form4-09282026_050908.xml · derivative · entry 1

Tamayo Louis Edward · CIK 0002083206 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,750

Underlying: Common Stock · 54,750 shares

Expires 2036-09-23

F1 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on September 24, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001995218-26-000017 · form4-09282026_050901.xml · derivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 145,500

Underlying: Common Stock · 145,500 shares

Expires 2036-09-23

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on September 24, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0002024096-26-000015 · form4-09282026_050904.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 138,288

F1 · shares: The reporting person is voluntarily reporting the acquisition of shares of the Issuer's common stock pursuant to the Lexeo Therapeutics, Inc. 2023 Employee Stock Purchase Plan. This transaction is exempt under both Rule 16b-3(c) and Rule 16b-3(d).

F2 · balance_after: Includes 97,026 Restricted Stock Units.

SEC source: 0002109299-26-000009 · form4-09282026_050906.xml · nonDerivative · entry 1

Bhalla Narinder Pal · CIK 0002109299 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,908

F1 · shares: The reporting person is voluntarily reporting the acquisition of shares of the Issuer's common stock pursuant to the Lexeo Therapeutics, Inc. 2023 Employee Stock Purchase Plan. This transaction is exempt under both Rule 16b-3(c) and Rule 16b-3(d).

F2 · balance_after: Includes 49,500 Restricted Stock Units.

SEC source: 0001995218-26-000017 · form4-09282026_050901.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 376,778

F1 · shares: The reporting person is voluntarily reporting the acquisition of shares of the Issuer's common stock pursuant to the Lexeo Therapeutics, Inc. 2023 Employee Stock Purchase Plan. This transaction is exempt under both Rule 16b-3(c) and Rule 16b-3(d).

F2 · balance_after: Includes 242,911 Restricted Stock Units.

SEC source: 0002083206-26-000007 · form4-08192026_050809.xml · nonDerivative · entry 1

Tamayo Louis Edward · CIK 0002083206 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,907

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.83 to $5.01. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 78,415 Restricted Stock Units.

SEC source: 0002024096-26-000013 · form4-08192026_050801.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 136,178

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.94 to $5.01. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 97,026 Restricted Stock Units.

SEC source: 0001995218-26-000015 · form4-08192026_050805.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 374,472

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.83 to $5.01. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 242,911 Restricted Stock Units.

SEC source: 0002083206-26-000005 · form4-07012026_100733.xml · nonDerivative · entry 2

Tamayo Louis Edward · CIK 0002083206 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 97,024

F1 · kind: Represents a sale to cover tax obligations on the release of performance Restricted Stock Units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.33 to $4.73. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 89,665 RSUs. Each RSU represents a contingent right to receive one share of Common Stock of the Issuer.

SEC source: 0002024096-26-000011 · form4-07012026_100702.xml · nonDerivative · entry 2

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 137,482

F1 · kind: Represents a sale to cover tax obligations on the release of performance Restricted Stock Units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.35 to $4.73. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 100,621 RSUs. Each RSU represents a contingent right to receive one share of Common Stock of the Issuer.

SEC source: 0002109299-26-000007 · form4-07012026_100718.xml · nonDerivative · entry 2

Bhalla Narinder Pal · CIK 0002109299 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 82,194

F1 · kind: Represents a sale to cover tax obligations on the release of performance Restricted Stock Units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.341 to $4.73. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 49,500 RSUs. Each RSU represents a contingent right to receive one share of Common Stock of the Issuer.

SEC source: 0001995218-26-000013 · form4-07012026_100715.xml · nonDerivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 377,817

F1 · kind: Represents a sale to cover tax obligations on the release of performance Restricted Stock Units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $4.3402 to $4.7507. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 252,130 RSUs. Each RSU represents a contingent right to receive one share of Common Stock of the Issuer.

SEC source: 0002083206-26-000005 · form4-07012026_100733.xml · nonDerivative · entry 1

Tamayo Louis Edward · CIK 0002083206 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 101,665

SEC source: 0002024096-26-000011 · form4-07012026_100702.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 142,148

SEC source: 0002109299-26-000007 · form4-07012026_100718.xml · nonDerivative · entry 1

Bhalla Narinder Pal · CIK 0002109299 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 104,500

SEC source: 0001995218-26-000013 · form4-07012026_100715.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 403,764

SEC source: 0001816206-26-000005 · form4-06292026_080640.xml · derivative · entry 1

Van Hauwermeiren Timothy · CIK 0001816206 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0001458116-26-000002 · form4-06292026_080651.xml · derivative · entry 1

Altschuler Steven · CIK 0001458116 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0001250086-26-000002 · form4-06292026_080624.xml · derivative · entry 1

DIAZ REINALDO M · CIK 0001250086 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0001193675-26-000002 · form4-06292026_080630.xml · derivative · entry 1

CHOLMONDELEY PAULA H · CIK 0001193675 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0001722234-26-000002 · form4-06292026_080602.xml · derivative · entry 1

Agger Mette Kirstine · CIK 0001722234 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0001849458-26-000001 · form4-06292026_080640.xml · derivative · entry 1

Tanguler Tolga · CIK 0001849458 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0001931514-26-000002 · form4-06292026_080620.xml · derivative · entry 1

COOPERSTONE BRENDA · CIK 0001931514 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-06-24

F1 · derivative.exercise_date: 100% of the shares underlying the option shall vest, and become exercisable, on the earlier of one year following the grant date or the next annual meeting of stockholders, subject to the Reporting Person's continuous service on such date.

SEC source: 0002024096-26-000009 · form4-05202026_040507.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,088

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $5.06 to $5.11. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 100,621 Restricted Stock Units.

SEC source: 0001995218-26-000011 · form4-05202026_040505.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 336,764

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $5.03 to $5.11. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 252,130 Restricted Stock Units.

SEC source: 0001777421-26-000003 · form4-04302026_080451.xml · derivative · entry 1

Sepp-Lorenzino Laura · CIK 0001777421 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2036-04-27

F1 · derivative.exercise_date: The shares subject to the option shall vest and become exercisable in equal annual installments over a three year period such that the option is fully vested on the third anniversary of the date of grant, subject to the Reporting Person's continuous service.

SEC source: 0001995218-26-000009 · form4-04072026_040401.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 340,106

F1 · kind: The sales in this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 13, 2025.

F2 · price: This transaction was executed in multiple trades at prices ranging from $5.56 to $5.94. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 261,349 Restricted Stock Units (RSU's). Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU.

SEC source: 0002024096-26-000007 · form4-03182026_010330.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 131,390

F1 · shares: The reporting person is voluntarily reporting the acquisition of shares of the Issuer's common stock pursuant to the Lexeo Therapeutics, Inc. 2023 Employee Stock Purchase Plan. This transaction is exempt under both Rule 16b-3(c) and Rule 16b-3(d).

F2 · balance_after: Includes 104,216 restricted stock units.

SEC source: 0001995218-26-000006 · form4-03182026_010332.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 395,106

F1 · shares: The reporting person is voluntarily reporting the acquisition of shares of the Issuer's common stock pursuant to the Lexeo Therapeutics, Inc. 2023 Employee Stock Purchase Plan. This transaction is exempt under both Rule 16b-3(c) and Rule 16b-3(d).

F2 · balance_after: Includes 261,349 Restricted Stock Units.

SEC source: 0002024096-26-000005 · form4-02202026_050205.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,460

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $6.22 to $6.47. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 104,216 Restricted Stock Units.

SEC source: 0001995218-26-000004 · form4-02202026_050203.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 392,483

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $6.22 to $6.50. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 261,349 Restricted Stock Units.

SEC source: 0002109299-26-000004 · form4-02172026_040201.xml · derivative · entry 2

Bhalla Narinder Pal · CIK 0002109299 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 297,000

Underlying: Common Stock · 297,000 shares

Expires 2036-02-12

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on January 20, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0002109299-26-000004 · form4-02172026_040201.xml · nonDerivative · entry 1

Bhalla Narinder Pal · CIK 0002109299 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 49,500

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2027, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

F2 · balance_after: Includes 49,500 RSUs.

SEC source: 0002083206-26-000002 · form4-02062026_050201.xml · derivative · entry 2

Tamayo Louis Edward · CIK 0002083206 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 226,665

Underlying: Common Stock · 226,665 shares

Expires 2036-02-03

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on February 4, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0002083206-26-000002 · form4-02062026_050201.xml · nonDerivative · entry 1

Tamayo Louis Edward · CIK 0002083206 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,665

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2027, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

F2 · balance_after: The reported securities are RSUs.

SEC source: 0002024096-26-000002 · form4-02062026_050203.xml · derivative · entry 2

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 260,000

Underlying: Common Stock · 260,000 shares

Expires 2036-02-03

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on February 4, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0002024096-26-000002 · form4-02062026_050203.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 128,476

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2027, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

F2 · balance_after: Includes 112,733 RSUs.

SEC source: 0001995218-26-000002 · form4-02062026_050205.xml · derivative · entry 2

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 646,665

Underlying: Common Stock · 260,000 shares

Expires 2036-02-03

F3 · derivative.exercise_date: 25% of the shares underlying the option vest and become exercisable on February 4, 2027, and 1/48th of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service.

SEC source: 0001995218-26-000002 · form4-02062026_050205.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 402,656

F1 · shares: The reported securities are restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of Common Stock of the Issuer. Twenty-five percent (25%) of the RSUs shall vest on February 15, 2027, and 1/16th of the RSUs shall vest in quarterly installments thereafter on the Issuer's standard quarterly vesting dates, subject to the Reporting Person's continued service through each applicable vesting date.

F2 · balance_after: Includes 290,022 RSUs.

SEC source: 0002009350-25-000005 · form4-11202025_101104.xml · nonDerivative · entry 1

See Tai Sandi · CIK 0002009350 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,476

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $9.09 to $9.37. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 48,098 RSUs.

SEC source: 0001995218-25-000007 · form4-11202025_101125.xml · nonDerivative · entry 1

Townsend Richard Nolan · CIK 0001995218 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 240,991

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $9.09 to $9.37. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 128,357 Restricted Stock Units.

SEC source: 0001994972-25-000005 · form4-11202025_101109.xml · nonDerivative · entry 1

Adler Eric · CIK 0001994972 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,646

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $9.09 to $9.37. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 58,866 RSUs.

SEC source: 0001995009-25-000005 · form4-11202025_101103.xml · nonDerivative · entry 1

Robertson Jenny · CIK 0001995009 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,381

F1 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $9.09 to $9.37. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F3 · balance_after: Includes 49,607 RSUs.

SEC source: 0002024096-26-000004 · form4a-02202026_050201.xml · nonDerivative · entry 1

Otero Jose Manuel · CIK 0002024096 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,476

F1 · date: On November 20, 2025, the reporting person filed a Form 4 which inadvertently reported that a sale to cover tax obligations occurred on August 18, 2025. In fact, as reported in this amendment, the sale occurred on November 18, 2025.

F2 · kind: Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs").

F3 · price: This transaction was executed in multiple trades at prices ranging from $9.09 to $9.37. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F4 · balance_after: Includes 47,733 RSUs.

SEC source: 0002024096-25-000003 · form4-10172025_111011.xml · nonDerivative · entry 3

Otero Jose Manuel · CIK 0002024096 · Chief Technical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,197

F1 · kind: Represents a sale to cover tax obligations on the release of Restricted Stock Units ("RSUs").

F3 · price: This transaction was executed in multiple trades at prices ranging from $9.53 to $9.59. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F4 · balance_after: Includes 49,687 RSUs. Each RSU represents a contingent right to receive one share of Common Stock of the Issuer.

SEC source: 0002024096-25-000003 · form4-10172025_111011.xml · nonDerivative · entry 2

Otero Jose Manuel · CIK 0002024096 · Chief Technical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 64,221

F1 · kind: Represents a sale to cover tax obligations on the release of Restricted Stock Units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $8.53 to $9.52. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

SEC source: 0002009350-25-000003 · form4-10172025_111028.xml · nonDerivative · entry 3

See Tai Sandi · CIK 0002009350 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,862

F1 · kind: Represents a sale to cover tax obligations on the release of Restricted Stock Units ("RSUs").

F3 · price: This transaction was executed in multiple trades at prices ranging from $9.53 to $9.59. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.

F4 · balance_after: Includes 49,138 RSUs. Each RSU represents a contingent right to receive one share of Common Stock of the Issuer.

SEC source: 0002009350-25-000003 · form4-10172025_111028.xml · nonDerivative · entry 2

See Tai Sandi · CIK 0002009350 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,906

F1 · kind: Represents a sale to cover tax obligations on the release of Restricted Stock Units ("RSUs").

F2 · price: This transaction was executed in multiple trades at prices ranging from $8.53 to $9.52. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.