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person · Reporting owner

Krishnan Suma

Disclosed activity across 1 company

Tapewire entity
10296
SEC CIK
0001298711

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Krystal Biotech, Inc.KRYS · Entity 3500Director · President, R&D · 10% ownerSeptember 04, 2026September 04, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Krystal Biotech, Inc.

Report date September 04, 2026 · Filed September 04, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect1,302,145 Ending reported balance After 2026-09-04 transaction · row 13
13 source rows · reconciled sequence

Row 1 · 2026-09-04 · Sale · Disposed 520 · Balance 1,326,625

F1: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Krish S. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by her spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of her pecuniary interest therein.

F2: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated.

F3: The transaction was executed in multiple trades ranging from $353.98 to $354.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 2 · 2026-09-04 · Sale · Disposed 2,006 · Balance 1,324,619

F4: The transaction was executed in multiple trades ranging from $354.98 to $355.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 3 · 2026-09-04 · Sale · Disposed 3,267 · Balance 1,321,352

F5: The transaction was executed in multiple trades ranging from $355.98 to $356.96. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 4 · 2026-09-04 · Sale · Disposed 3,962 · Balance 1,317,390

F6: The transaction was executed in multiple trades ranging from $356.99 to $357.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 5 · 2026-09-04 · Sale · Disposed 3,180 · Balance 1,314,210

F7: The transaction was executed in multiple trades ranging from $357.99 to $358.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 6 · 2026-09-04 · Sale · Disposed 3,392 · Balance 1,310,818

F8: The transaction was executed in multiple trades ranging from $358.99 to $359.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 7 · 2026-09-04 · Sale · Disposed 2,320 · Balance 1,308,498

F9: The transaction was executed in multiple trades ranging from $360.01 to $361.005. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 8 · 2026-09-04 · Sale · Disposed 1,242 · Balance 1,307,256

F10: The transaction was executed in multiple trades ranging from $361.02 to $362.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 9 · 2026-09-04 · Sale · Disposed 1,992 · Balance 1,305,264

F11: The transaction was executed in multiple trades ranging from $362.02 to $363.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 10 · 2026-09-04 · Sale · Disposed 565 · Balance 1,304,699

F12: The transaction was executed in multiple trades ranging from $363.05 to $364.01. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 11 · 2026-09-04 · Sale · Disposed 1,329 · Balance 1,303,370

F13: The transaction was executed in multiple trades ranging from $364.07 to $365.05. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 12 · 2026-09-04 · Sale · Disposed 826 · Balance 1,302,544

F14: The transaction was executed in multiple trades ranging from $365.07 to $366.03. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Row 13 · 2026-09-04 · Sale · Disposed 399 · Balance 1,302,145

F15: The transaction was executed in multiple trades ranging from $366.39 to $366.91. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Common StockSEC Table I · non-derivativeIndirectBy Krishnan Spousal Trust90,000 Reported balance Holding disclosure · report date 2026-09-04 · row 14 Holding and transaction disclosures are not merged.
1 source row

Row 14 · Balance 90,000

F16: Held by the Krishnan Spousal Trust, an irrevocable trust established by Mr. Krishnan for the benefit of Mrs. Krishnan who serves as a co-trustee and shares voting and investment power with a 3rd party co-trustee.

Common StockSEC Table I · non-derivativeIndirectBy Suma Mani Krishnan Trust51,010 Reported balance Holding disclosure · report date 2026-09-04 · row 15 Holding and transaction disclosures are not merged.
1 source row

Row 15 · Balance 51,010

F17: Held by the Suma Mani Krishnan Trust dated July 7, 2026. The Reporting Person is the grantor and trustee of the trust, has the power to revoke the trust, and has voting and investment power with respect to the shares held by the trust.

Common StockSEC Table I · non-derivativeIndirectBy Krishnan Family Trust50,000 Reported balance Holding disclosure · report date 2026-09-04 · row 16 Holding and transaction disclosures are not merged.
1 source row

Row 16 · Balance 50,000

F18: Held by the Krishnan Family Trust. The Reporting Person and her spouse are each joint beneficial owners of the trust with joint voting and investment control.

Filing footnotes · ownership attribution and instrument terms

F1: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Krish S. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by her spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of her pecuniary interest therein.

F2: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated.

F3: The transaction was executed in multiple trades ranging from $353.98 to $354.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F4: The transaction was executed in multiple trades ranging from $354.98 to $355.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F5: The transaction was executed in multiple trades ranging from $355.98 to $356.96. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F6: The transaction was executed in multiple trades ranging from $356.99 to $357.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F7: The transaction was executed in multiple trades ranging from $357.99 to $358.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F8: The transaction was executed in multiple trades ranging from $358.99 to $359.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F9: The transaction was executed in multiple trades ranging from $360.01 to $361.005. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F10: The transaction was executed in multiple trades ranging from $361.02 to $362.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F11: The transaction was executed in multiple trades ranging from $362.02 to $363.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F12: The transaction was executed in multiple trades ranging from $363.05 to $364.01. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13: The transaction was executed in multiple trades ranging from $364.07 to $365.05. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F14: The transaction was executed in multiple trades ranging from $365.07 to $366.03. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F15: The transaction was executed in multiple trades ranging from $366.39 to $366.91. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F16: Held by the Krishnan Spousal Trust, an irrevocable trust established by Mr. Krishnan for the benefit of Mrs. Krishnan who serves as a co-trustee and shares voting and investment power with a 3rd party co-trustee.

F17: Held by the Suma Mani Krishnan Trust dated July 7, 2026. The Reporting Person is the grantor and trustee of the trust, has the power to revoke the trust, and has voting and investment power with respect to the shares held by the trust.

F18: Held by the Krishnan Family Trust. The Reporting Person and her spouse are each joint beneficial owners of the trust with joint voting and investment control.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 399 $366.56 $146,255.84
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 13

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,302,145

F15 · price: The transaction was executed in multiple trades ranging from $366.39 to $366.91. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 826 $365.41 $301,831.88
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 12

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,302,544

F14 · price: The transaction was executed in multiple trades ranging from $365.07 to $366.03. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,329 $364.48 $484,390.07
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 11

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,303,370

F13 · price: The transaction was executed in multiple trades ranging from $364.07 to $365.05. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 565 $363.34 $205,287.33
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 10

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,304,699

F12 · price: The transaction was executed in multiple trades ranging from $363.05 to $364.01. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,992 $362.65 $722,404.18
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 9

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,305,264

F11 · price: The transaction was executed in multiple trades ranging from $362.02 to $363.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,242 $361.61 $449,119.62
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 8

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,307,256

F10 · price: The transaction was executed in multiple trades ranging from $361.02 to $362.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,320 $360.47 $836,281.12
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 7

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,308,498

F9 · price: The transaction was executed in multiple trades ranging from $360.01 to $361.005. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,392 $359.39 $1,219,037.99
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 6

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,310,818

F8 · price: The transaction was executed in multiple trades ranging from $358.99 to $359.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,180 $358.42 $1,139,776.55
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 5

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,314,210

F7 · price: The transaction was executed in multiple trades ranging from $357.99 to $358.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,962 $357.57 $1,416,708.98
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 4

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,317,390

F6 · price: The transaction was executed in multiple trades ranging from $356.99 to $357.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,267 $356.37 $1,164,253.93
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 3

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,321,352

F5 · price: The transaction was executed in multiple trades ranging from $355.98 to $356.96. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,006 $355.57 $713,277.23
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 2

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,324,619

F4 · price: The transaction was executed in multiple trades ranging from $354.98 to $355.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
September 04, 2026 Filed Sep 4, 2026 23:15 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 520 $354.54 $184,360.80
Disclosure

SEC source: 0001298711-26-000009 · wk-form4_1788563746.xml · nonDerivative · entry 1

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,326,625

F1 · kind: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Krish S. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by her spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of her pecuniary interest therein.

F2 · price: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan has reached the maximum number of shares to be sold under such plan and has terminated.

F3 · price: The transaction was executed in multiple trades ranging from $353.98 to $354.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 240 $311.65 $74,796.00
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 11

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,378,155

F12 · price: The transaction was executed in multiple trades ranging from $311.50 to $311.77. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,039 $310.94 $634,000.54
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 10

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,378,395

F11 · price: The transaction was executed in multiple trades ranging from $310.44 to $311.41. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,801 $309.95 $868,156.23
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 9

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,380,434

F10 · price: The transaction was executed in multiple trades ranging from $309.43 to $310.38. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,803 $308.89 $1,174,707.91
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 8

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,383,235

F9 · price: The transaction was executed in multiple trades ranging from $308.38 to $309.36. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 12,729 $307.81 $3,918,070.21
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 7

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,387,038

F8 · price: The transaction was executed in multiple trades ranging from $307.38 to $308.37. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,348 $307.09 $413,963.79
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 6

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,399,767

F7 · price: The transaction was executed in multiple trades ranging from $306.38 to $307.37. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

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June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 480 $305.87 $146,815.20
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 5

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,401,115

F6 · price: The transaction was executed in multiple trades ranging from $305.19 to $306.00. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 400 $304.89 $121,957.56
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 4

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,401,595

F5 · price: The transaction was executed in multiple trades ranging from $304.07 to $304.98. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 247 $303.17 $74,883.06
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 3

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,401,995

F4 · price: The transaction was executed in multiple trades ranging from $303.05 to $303.77. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 593 $302.25 $179,234.72
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 2

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,402,242

F3 · price: The transaction was executed in multiple trades ranging from $302.05 to $303.01. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
June 04, 2026 Filed Jun 5, 2026 22:40 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 320 $300.75 $96,240.00
Disclosure

SEC source: 0001298711-26-000006 · wk-form4_1780699235.xml · nonDerivative · entry 1

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,402,835

F1 · kind: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Krish S. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by her spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of her pecuniary interest therein.

F2 · shares: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan started on December 4, 2025, and will terminate on December 4, 2026, or earlier in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,700 $266.42 $452,918.08
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 10

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,403,155

F12 · price: The transaction was executed in multiple trades ranging from $266 to $266.93. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 6,000 $265.16 $1,590,979.20
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 9

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,404,855

F11 · price: The transaction was executed in multiple trades ranging from $265 to $265.73. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 4,852 $264.64 $1,284,019.21
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 8

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,410,855

F10 · price: The transaction was executed in multiple trades ranging from $264 to $264.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,248 $263.58 $592,534.81
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 7

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,415,707

F9 · price: The transaction was executed in multiple trades ranging from $263 to $263.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,938 $262.35 $508,430.23
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 6

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,417,955

F8 · price: The transaction was executed in multiple trades ranging from $262 to $262.8. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,931 $261.41 $766,198.28
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 5

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,419,893

F7 · price: The transaction was executed in multiple trades ranging from $261 to $261.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,667 $260.37 $954,762.49
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 4

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,422,824

F6 · price: The transaction was executed in multiple trades ranging from $259.98 to $260.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 668 $259.61 $173,419.15
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 3

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,426,491

F5 · price: The transaction was executed in multiple trades ranging from $258.98 to $259.97. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 589 $258.54 $152,280.30
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 2

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,427,159

F4 · price: The transaction was executed in multiple trades ranging from $257.93 to $258.92. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 23:23 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 407 $257.32 $104,728.67
Disclosure

SEC source: 0001298711-26-000004 · wk-form4_1772839386.xml · nonDerivative · entry 1

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,427,748

F1 · kind: The Reporting Person may be deemed to beneficially own shares of the Issuer's common stock directly owned by the Reporting Person's spouse, Krish S. Krishnan. Such shares and transactions by the Reporting Person's spouse are not included in this Form 4, as they are being reported separately on a Form 4 filed by her spouse. The Reporting Person disclaims beneficial ownership of such shares except to the extent of her pecuniary interest therein.

F2 · shares: The sales reported in this Form 4 were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025. The Rule 10b5-1 trading plan started on December 4, 2025 and will terminate on December 4, 2026, or earlier in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F3 · price: The transaction was executed in multiple trades ranging from $256.68 to $257.67. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantPerformance Stock Units · Derivative 43,536 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · derivative · entry 17

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,536

Underlying: Common Stock · 43,536 shares

Expires not disclosed

F18 · derivative.exercise_price: Each PSU represents a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the three year performance period, as approved by the Company's Compensation Committee, and the Reporting Person's continued service to the Company on the vesting date.

F19 · shares: The number of PSUs in this column represents the number of shares of common stock the Reporting Person will receive assuming achievement of all of the performance criteria set by the Company's Compensation Committee for this PSU award and full vesting of this PSU award.

F20 · derivative.exercise_date: If any applicable portion of the performance criteria have been achieved, the PSU award shall cliff vest on February 27, 2029.

F21 · derivative.expiration_date: If some or all of the performance criteria are not achieved, the applicable portion of the PSU award will be forfeited.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantRestricted Stock Units · Derivative 7,256 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · derivative · entry 16

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,256

Underlying: Common Stock · 7,256 shares

Expires not disclosed

F16 · derivative.exercise_price: Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date.

F17 · derivative.exercise_date: The RSUs vest in four equal annual installments with the first installment vesting on February 27, 2027.

F17 · derivative.expiration_date: The RSUs vest in four equal annual installments with the first installment vesting on February 27, 2027.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantStock Option (Right to Buy) · Derivative 18,100 $0.00 Strike: $275.64 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · derivative · entry 15

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,100

Underlying: Common Stock · 18,100 shares

Expires 2036-02-26

F15 · derivative.exercise_date: The stock options vest in four equal annual installments beginning on February 27, 2027.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionRestricted Stock Units · Derivative 4,000 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · derivative · entry 14

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,000

Underlying: Common Stock · 4,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: 16,000 restricted stock units ("RSUs") were granted on February 28, 2025. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 4,000 RSUs, vesting on February 27, 2026.

F4 · derivative.exercise_date: 16,000 restricted stock units ("RSUs") were granted on February 28, 2025. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 4,000 RSUs, vesting on February 27, 2026.

F4 · derivative.expiration_date: 16,000 restricted stock units ("RSUs") were granted on February 28, 2025. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 4,000 RSUs, vesting on February 27, 2026.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionPerformance Stock Units · Derivative 22,500 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · derivative · entry 13

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 22,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: 45,000 performance stock units ("PSUs") were granted on February 29, 2024. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 22,500 PSUs, vested on February 27, 2026.

F1 · derivative.exercise_date: 45,000 performance stock units ("PSUs") were granted on February 29, 2024. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 22,500 PSUs, vested on February 27, 2026.

F1 · derivative.expiration_date: 45,000 performance stock units ("PSUs") were granted on February 29, 2024. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 22,500 PSUs, vested on February 27, 2026.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Tax withholdingCommon Stock 2,605 $275.64 $718,042.20
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 10

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,500,253

F7 · shares: These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Krish S. Krishnan.

F13 · shares: Represents number of shares of common stock surrendered to the Company for tax withholding by the Reporting Person's spouse, Krish S. Krishnan, upon the vesting of 5,725 RSUs on February 27, 2026.

F3 · price: The closing price on February 27, 2026 of the Company's common stock on the Nasdaq Global Select Market.

F8 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionCommon Stock 5,725 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 9

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,502,858

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · shares: These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Krish S. Krishnan.

F12 · shares: 22,900 restricted stock units ("RSUs") were granted on February 28, 2025, to the Reporting Person's spouse, Krish S. Krishnan. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's spouse continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 5,725 RSUs, vesting on February 27, 2026.

F8 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Tax withholdingCommon Stock 11,942 $275.64 $3,291,692.88
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 8

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,497,133

F7 · shares: These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Krish S. Krishnan.

F11 · shares: Represents number of shares of common stock surrendered to the Company for tax withholding by the Reporting Person's spouse, Krish S. Krishnan, upon the vesting of 26,250 PSUs on February 27, 2026.

F3 · price: The closing price on February 27, 2026 of the Company's common stock on the Nasdaq Global Select Market.

F8 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionCommon Stock 26,250 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 7

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,509,075

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · shares: These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Krish S. Krishnan.

F10 · shares: 52,500 PSUs were granted on February 29, 2024, to the Reporting Person's spouse, Krish S. Krishnan. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's spouse continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 26,250 PSUs, vested on February 27, 2026.

F8 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Tax withholdingCommon Stock 3,981 $275.64 $1,097,322.84
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 6

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,482,825

F7 · shares: These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Krish S. Krishnan.

F9 · shares: Represents number of shares of common stock surrendered to the Company for tax withholding by the Reporting Person's spouse, Krish S. Krishnan, upon the vesting of 8,750 RSUs on February 27, 2026.

F3 · price: The closing price on February 27, 2026 of the Company's common stock on the Nasdaq Global Select Market.

F8 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionCommon Stock 8,750 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 5

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 1,486,806

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · shares: 35,000 restricted stock units ("RSUs") were granted on February 29, 2024, to the Reporting Person's spouse, Krish S. Krishnan. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's spouse continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the second installment, or 8,750 RSUs, vesting on February 27, 2026.

F7 · shares: These same shares are also being reported on a Form 4 by the Reporting Person's spouse, Krish S. Krishnan.

F8 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Tax withholdingCommon Stock 1,820 $275.64 $501,664.80
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 4

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,428,155

F5 · shares: Represents the number of shares of common stock surrendered to the Company for tax withholding upon the vesting of 4,000 RSUs on February 27, 2026.

F3 · price: The closing price on February 27, 2026 of the Company's common stock on the Nasdaq Global Select Market.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionCommon Stock 4,000 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 3

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,429,975

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · shares: 16,000 restricted stock units ("RSUs") were granted on February 28, 2025. Each RSU represents a contingent right to receive one share of the Company's common stock, subject to the Reporting Person's continued service to the Company on each applicable vesting date. The RSUs vest ratably over a four-year period with the first installment, or 4,000 RSUs, vesting on February 27, 2026.

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February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Tax withholdingCommon Stock 10,236 $275.64 $2,821,451.04
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 2

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,425,975

F2 · shares: Represents the number of shares of common stock surrendered to the Company for tax withholding upon the vesting of 22,500 PSUs on February 27, 2026.

F3 · price: The closing price on February 27, 2026 of the Company's common stock on the Nasdaq Global Select Market.

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February 27, 2026 Filed Mar 3, 2026 23:33 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionCommon Stock 22,500 $0.00 $0.00
Disclosure

SEC source: 0001298711-26-000002 · wk-form4_1772580780.xml · nonDerivative · entry 1

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,436,211

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · shares: 45,000 performance stock units ("PSUs") were granted on February 29, 2024. Each PSU represented a contingent right to receive one share of the Company's common stock, subject to the achievement of certain performance criteria during the year ended December 31, 2024, as approved by the Company's Compensation Committee, and the Reporting Person's continued service to the Company on each applicable vesting date following such achievement. The PSUs vested ratably over a two-year period. All of the performance criteria were achieved and the remaining one-half of the PSUs granted, or 22,500 PSUs, vested on February 27, 2026.

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December 05, 2025 Filed Dec 5, 2025 23:56 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GiftCommon Stock 5,000 $0.00 $0.00
Disclosure

SEC source: 0001298711-25-000013 · wk-form4_1764978975.xml · nonDerivative · entry 19

Krishnan Suma · CIK 0001298711 · Director · President, R&D · 10% owner

10b5-1 filing: Plan reported

Ownership: Indirect · By Spouse

Disclosed balance after: 1,478,056

F21 · kind: Represents a bona fide gift of Krystal Biotech, Inc.'s Common Stock to a charitable donor-advised fund.

F13 · ownership.nature: Directly beneficially owned by Krish S. Krishnan, the spouse of the Reporting Person.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.