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person · Reporting owner

JANNEY DANIEL

Disclosed activity across 6 companies

Tapewire entity
63327
SEC CIK
0001198325

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Allakos Inc.ALLK · Entity 79644DirectorMay 25, 2023May 30, 2023
Esperion Therapeutics, Inc.ESPR · Entity 30796DirectorMay 27, 2021May 28, 2021
Krystal Biotech, Inc.KRYS · Entity 3500DirectorSeptember 14, 2026September 17, 2026
SUTRO BIOPHARMA, INC.STRO · Entity 5797DirectorJune 17, 2019June 19, 2019
VIVEVE MEDICAL, INC.VIVE · Entity 11899DirectorDecember 31, 2018January 02, 2019

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Allakos Inc.

Report date May 25, 2023 · Filed May 30, 2023

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $4.81 · Expires 2033-05-25Direct86,762 Reported balance After 2023-05-25 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2023-05-25 · Grant · Acquired 86,762 · Balance 86,762

F1: The option vests as to 100% of the shares on the earlier of (i) the one-year anniversary of the date of grant or (ii) the date of the Issuer's next Annual Meeting of stockholders that occurs following the grant, subject to the Reporting Person continuing as a service provider through each such date.

Filing footnotes · ownership attribution and instrument terms

F1: The option vests as to 100% of the shares on the earlier of (i) the one-year anniversary of the date of grant or (ii) the date of the Issuer's next Annual Meeting of stockholders that occurs following the grant, subject to the Reporting Person continuing as a service provider through each such date.

Esperion Therapeutics, Inc.

Report date May 27, 2021 · Filed May 28, 2021

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect23,449 Reported balance After 2021-05-27 transaction · row 1
1 source row

Row 1 · 2021-05-27 · Grant · Acquired 12,376 · Balance 23,449

F1: The shares vest in full on the earlier of (i) May 27, 2022 and (ii) the Issuer's next annual meeting of stockholders following May 27, 2021.

Common StockSEC Table I · non-derivativeIndirectBy Alta Bioequities, L.P.24,565 Reported balance Holding disclosure · report date 2021-05-27 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 24,565

F2: On February 28, 2018, Alta Partners VIII, L.P. ("APVIII") distributed 624,564 shares of Common Stock on a pro rata basis, for no additional consideration, to its partners, which distribution was exempt from Section 16 of the Exchange Act pursuant to Rule 16a-9 and Rule 16a-13. Alta Bioequities, L.P. ("Alta Bioequities") received 24,565 of these shares. Alta Bioequities Management, LLC is the general partner of Alta Bioequities L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC and may be deemed to have voting and investment power over the shares owned by Alta Bioequities, L.P.

Filing footnotes · ownership attribution and instrument terms

F1: The shares vest in full on the earlier of (i) May 27, 2022 and (ii) the Issuer's next annual meeting of stockholders following May 27, 2021.

F2: On February 28, 2018, Alta Partners VIII, L.P. ("APVIII") distributed 624,564 shares of Common Stock on a pro rata basis, for no additional consideration, to its partners, which distribution was exempt from Section 16 of the Exchange Act pursuant to Rule 16a-9 and Rule 16a-13. Alta Bioequities, L.P. ("Alta Bioequities") received 24,565 of these shares. Alta Bioequities Management, LLC is the general partner of Alta Bioequities L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC and may be deemed to have voting and investment power over the shares owned by Alta Bioequities, L.P.

Krystal Biotech, Inc.

Report date September 14, 2026 · Filed September 17, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $340.03 · Expires 2036-09-13Direct1,187 Reported balance After 2026-09-14 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-09-14 · Grant · Acquired 1,187 · Balance 1,187

F1: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Restricted Stock AwardSEC Table II · derivative / convertible securityDirect471 Reported balance After 2026-09-14 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-09-14 · Grant · Acquired 471 · Balance 471

F2: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Filing footnotes · ownership attribution and instrument terms

F1: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F2: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

SUTRO BIOPHARMA, INC.

Report date June 17, 2019 · Filed June 19, 2019

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (right to buy Common Stock)SEC Table II · derivative / convertible security · Conversion / exercise price $11.12 · Expires 2029-06-16Direct11,610 Reported balance After 2019-06-17 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2019-06-17 · Grant · Acquired 11,610 · Balance 11,610

F1: The option vests as to 1/12th of the total shares monthly, beginning on July 7, 2019, with 100% of the total shares vested and exercisable on June 7, 2020, subject to the reporting person's provision of service to the issuer on each vesting date.

Filing footnotes · ownership attribution and instrument terms

F1: The option vests as to 1/12th of the total shares monthly, beginning on July 7, 2019, with 100% of the total shares vested and exercisable on June 7, 2020, subject to the reporting person's provision of service to the issuer on each vesting date.

VIVEVE MEDICAL, INC.

Report date December 31, 2018 · Filed January 02, 2019

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect60,579 Reported balance After 2018-12-31 transaction · row 1
1 source row

Row 1 · 2018-12-31 · Grant · Acquired 21,131 · Balance 60,579

F1: The reporting person is a participant in the Issuer's Amended and Restated 2013 Stock Option and Incentive Plan (the "Plan") and received a restricted stock award of 21,131 shares of common stock on December 31, 2018 (the "Grant Date"). The restricted stock award shall vest in full on the Grant Date.

Common StockSEC Table I · non-derivativeIndirectSee1,381,955 Reported balance Holding disclosure · report date 2018-12-31 · row 2 Holding and transaction disclosures are not merged.
1 source row

Row 2 · Balance 1,381,955

F2: Directly beneficially owned by Alta Bioequities, L.P.

F3: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. Daniel Janney is the Managing Director of Alta Bioequities Management, LLC and may be deemed to have voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. Each of Alta Bioequities Management, LLC and Mr. Janney disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: The reporting person is a participant in the Issuer's Amended and Restated 2013 Stock Option and Incentive Plan (the "Plan") and received a restricted stock award of 21,131 shares of common stock on December 31, 2018 (the "Grant Date"). The restricted stock award shall vest in full on the Grant Date.

F2: Directly beneficially owned by Alta Bioequities, L.P.

F3: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. Daniel Janney is the Managing Director of Alta Bioequities Management, LLC and may be deemed to have voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. Each of Alta Bioequities Management, LLC and Mr. Janney disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

Past disclosures · reporting ended (1)

No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.

Tyra Biosciences, Inc.

Report date September 17, 2021 · Filed September 17, 2021

Jointly reported with Alta Partners NextGen Fund II Management, LLC, Alta Partners NextGen Fund II, L.P., Hudson Peter A

Section 16 reporting ended · disclosed 2021-09-17. Current position is not established by this disclosure.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectSee footnote4,080,296 Last balance in matching sequence After 2021-09-17 transaction · row 2 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rows

Row 1 · 2021-09-17 · Conversion · Acquired 3,811,117 · Balance 3,924,046

F1: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F2: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

Row 2 · 2021-09-17 · Purchase · Acquired 156,250 · Balance 4,080,296

F2: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

Series A Preferred StockSEC Table II · derivative / convertible securityIndirectSee footnote0 Reported balance After 2021-09-17 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2021-09-17 · Conversion · Disposed 1,212,122 · Balance 0

F1: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F2: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

Series B Preferred StockSEC Table II · derivative / convertible securityIndirectSee footnote0 Reported balance After 2021-09-17 transaction · row 4 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 4 · 2021-09-17 · Conversion · Disposed 255,160 · Balance 0

F1: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F2: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

Filing footnotes · ownership attribution and instrument terms

F1: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F2: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
September 14, 2026 Filed Sep 17, 2026 00:01 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantRestricted Stock Award · Derivative 471 $0.00 $0.00
Disclosure

SEC source: 0001711279-26-000060 · wk-form4_1789603273.xml · derivative · entry 2

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 471

Underlying: Common Stock · 471 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Company's common stock.

F3 · derivative.exercise_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

F3 · derivative.expiration_date: The RSUs vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
September 14, 2026 Filed Sep 17, 2026 00:01 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantStock Option (Right to Buy) · Derivative 1,187 $0.00 Strike: $340.03 $0.00
Disclosure

SEC source: 0001711279-26-000060 · wk-form4_1789603273.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,187

Underlying: Common Stock · 1,187 shares

Expires 2036-09-13

F1 · derivative.exercise_date: The stock options vest in full on September 14, 2027, subject to continued service on the Company's Board of Directors through such date and to earlier vesting in certain circumstances described in the Company's Non-Employee Director Compensation Policy as in effect on the date of grant.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:28 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,373 $276.17 $655,343.10
Disclosure

SEC source: 0001711279-26-000023 · wk-form4_1772580519.xml · nonDerivative · entry 2

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 73,293

F1 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F4 · price: The transaction was executed in multiple trades ranging from $276 to $276.4924. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F3 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 27, 2026 Filed Mar 3, 2026 23:28 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 9,430 $275.45 $2,597,481.24
Disclosure

SEC source: 0001711279-26-000023 · wk-form4_1772580519.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 75,666

F1 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F2 · price: The transaction was executed in multiple trades ranging from $275 to $275.986. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F3 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 26, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,638 $276.32 $728,919.50
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 21

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 85,096

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F23 · price: The transaction was executed in multiple trades ranging from $276 to $276.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 26, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 5,103 $275.28 $1,404,759.96
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 20

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 87,734

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F22 · price: The transaction was executed in multiple trades ranging from $275 to $275.9782. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 25, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 700 $275.00 $192,500.00
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 19

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 92,837

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F21 · price: The transaction was executed in a single trade.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionStock Option (Right to Buy) · Derivative 37,895 $0.00 Strike: $2.46 $0.00
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · derivative · entry 22

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 37,895 shares

Expires 2026-11-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F24 · derivative.exercise_date: The options vested ratably over a four-year period beginning on November 10, 2016.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 2,425 $274.90 $666,626.92
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 18

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 93,537

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F20 · price: The transaction was executed in multiple trades ranging from $274.59 to $275. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 930 $269.50 $250,636.21
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 17

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 95,962

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F19 · price: The transaction was executed in multiple trades ranging from $269.1641 to $269.78. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,674 $268.67 $449,746.88
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 16

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 96,892

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F18 · price: The transaction was executed in multiple trades ranging from $268.0725 to $269.0705. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,891 $267.37 $505,596.67
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 15

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 98,566

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F17 · price: The transaction was executed in multiple trades ranging from $267.0631 to $268.0275. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 4,339 $266.62 $1,156,878.93
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 14

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 100,457

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F16 · price: The transaction was executed in multiple trades ranging from $266.06 to $267.0511. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,604 $265.54 $425,919.10
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 13

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 104,796

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F15 · price: The transaction was executed in multiple trades ranging from $265.04 to $266. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 900 $264.60 $238,136.04
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 12

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 106,400

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F14 · price: The transaction was executed in multiple trades ranging from $264.01 to $264.99. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 62 $263.05 $16,309.17
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 11

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 107,300

F11 · kind: The sale of common stock reported on this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

F12 · price: The transaction was executed in multiple trades ranging from $262.9496 to $263.1269. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F13 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 373 $271.09 $101,117.99
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 10

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F10 · price: The transaction was executed in multiple trades ranging from $270.650 to $271.610. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 370 $269.83 $99,836.43
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 9

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 373

F9 · price: The transaction was executed in multiple trades ranging from $269.610 to $270.140. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,963 $268.97 $1,065,923.75
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 8

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 743

F8 · price: The transaction was executed in multiple trades ranging from $268.540 to $269.530. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 6,671 $268.04 $1,788,079.50
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 7

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,706

F7 · price: The transaction was executed in multiple trades ranging from $267.520 to $268.510. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 11,673 $266.97 $3,116,310.46
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 6

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 11,377

F6 · price: The transaction was executed in multiple trades ranging from $266.520 to $267.510. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 8,986 $266.18 $2,391,885.39
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 5

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 23,050

F5 · price: The transaction was executed in multiple trades ranging from $265.520 to $266.510. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,557 $265.08 $942,878.18
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 4

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,036

F4 · price: The transaction was executed in multiple trades ranging from $264.520 to $265.495. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,733 $264.12 $457,727.93
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 3

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,593

F3 · price: The transaction was executed in multiple trades ranging from $263.510 to $264.450. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 569 $262.91 $149,594.08
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 2

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,326

F2 · price: The transaction was executed in multiple trades ranging from $262.480 to $263.400. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

Read SEC document
February 24, 2026 Filed Feb 26, 2026 23:49 UTC Krystal Biotech, Inc. KRYS · Entity 3500 Exercise / conversionCommon Stock 37,895 $2.46 $93,221.70
Disclosure

SEC source: 0001711279-26-000021 · wk-form4_1772149785.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 37,895

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The option exercise and sale reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan was entered into on November 25, 2025, and will terminate on November 5, 2026, subject to early termination in accordance with the terms of the Rule 10b5-1 trading plan, including upon completion of the sale of all of the shares of the Company's common stock subject to the Rule 10b5-1 trading plan.

Read SEC document
June 30, 2025 Filed Jun 30, 2025 22:14 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $137.46 $0.00
Disclosure

SEC source: 0001711279-25-000057 · wk-form4_1751321689.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2035-06-30

F1 · derivative.exercise_date: The options were awarded on June 30, 2025 and vest in equal monthly tranches over a one-year period.

Read SEC document
June 30, 2024 Filed Jul 1, 2024 23:34 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantStock Option (Right to Buy) · Derivative 5,000 $0.00 Strike: $183.64 $0.00
Disclosure

SEC source: 0001711279-24-000029 · wk-form4_1719876885.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2034-06-30

F1 · derivative.exercise_date: The options were awarded on June 30, 2024 and vest in equal monthly tranches over a one-year period.

Read SEC document
June 30, 2023 Filed Jul 3, 2023 20:20 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantStock Option (Right to Buy) · Derivative 6,800 $0.00 Strike: $117.40 $0.00
Disclosure

SEC source: 0001711279-23-000051 · wk-form4_1688415647.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,800

Underlying: Common Stock · 6,800 shares

Expires 2033-06-30

F1 · derivative.exercise_date: The options were awarded on June 30, 2023 and vest in equal monthly tranches over a one-year period.

Read SEC document
June 09, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 10,000 $128.53 $1,285,262.00
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 9

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 107,362

F7 · price: The transaction was executed in multiple trades ranging from $127.715 to $129.6100. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
June 09, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 5,000 $128.84 $644,187.50
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 8

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 117,362

F6 · price: The transaction was executed in multiple trades ranging from $128.5000 to $129.4800. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
June 09, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 3,935 $129.29 $508,773.07
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 7

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 122,362

F5 · price: The transaction was executed in multiple trades ranging from $129.0000 to $129.7400. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
June 08, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 5,000 $127.86 $639,306.00
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 6

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 126,297

F4 · price: The transaction was executed in multiple trades ranging from $127.7000 to $128.44. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
June 08, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 10,000 $127.96 $1,279,584.00
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 5

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 131,297

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
June 08, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 5,000 $127.96 $639,790.00
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 4

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 141,297

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

Read SEC document
June 08, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 5,388 $128.73 $693,616.10
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 3

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 146,297

F3 · price: The transaction was executed in multiple trades ranging from $128.5000 to $129.0600. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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June 08, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 1,073 $129.02 $138,440.39
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 2

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 151,685

F2 · price: The transaction was executed in multiple trades ranging from $129.0000 to $129.0600. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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June 08, 2023 Filed Jun 9, 2023 23:03 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 4,604 $127.96 $589,117.71
Disclosure

SEC source: 0001711279-23-000046 · wk-form4_1686351820.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 152,758

F1 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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May 25, 2023 Filed May 30, 2023 18:00 UTC Allakos Inc. ALLK · Entity 79644 GrantStock Option (Right to buy) · Derivative 86,762 $0.00 Strike: $4.81 $0.00
Disclosure

SEC source: 0001209191-23-032970 · doc4.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,762

Underlying: Common Stock · 86,762 shares

Expires 2033-05-25

F1 · derivative.exercise_date: The option vests as to 100% of the shares on the earlier of (i) the one-year anniversary of the date of grant or (ii) the date of the Issuer's next Annual Meeting of stockholders that occurs following the grant, subject to the Reporting Person continuing as a service provider through each such date.

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May 19, 2023 Filed May 23, 2023 20:20 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 50,000 $95.02 $4,751,185.00
Disclosure

SEC source: 0001711279-23-000042 · wf-form4_168487321853185.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 157,362

F1 · kind: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan started on September 12, 2022 and will terminate on September 11, 2023 and contemplates sales of 50,000 shares with a limit price of $95.00 per share.

F2 · price: The transaction was executed in multiple trades ranging from $95.0000 to $95.3800. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F3 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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May 09, 2023 Filed May 11, 2023 20:30 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 17,100 $90.74 $1,551,578.76
Disclosure

SEC source: 0001711279-23-000035 · wf-form4_168383702435561.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 207,362

F1 · kind: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan started on September 12, 2022 and will terminate on September 11, 2023 and contemplates sales of 25,000 shares with a limit price of $90.00 per share.

F2 · price: The transaction was executed in multiple trades ranging from $90.0000 to $91.1350. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F3 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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April 19, 2023 Filed Apr 21, 2023 20:10 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 7,900 $90.32 $713,493.24
Disclosure

SEC source: 0001711279-23-000023 · wf-form4_168210784238261.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · Directly beneficially owned by Alta Bioequities, L.P.

Disclosed balance after: 224,462

F1 · kind: The sales reported were pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person. The Rule 10b5-1 trading plan started on September 12, 2022 and will terminate on September 11, 2023 and contemplates sales of 25,000 shares with a limit price of $90.00 per share.

F2 · price: The transaction was executed in multiple trades ranging from $90.0000 to $90.3650. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range set forth herein.

F3 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.

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September 21, 2022 Filed Sep 23, 2022 16:25 UTC Allakos Inc. ALLK · Entity 79644 PurchaseCommon Stock 475,000 $5.02 $2,384,500.00
Disclosure

SEC source: 0001209191-22-051141 · doc4.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Alta Partners NextGen Fund I, L.P.

Disclosed balance after: 2,546,147

F1 · kind: Reports the purchase of shares in the underwritten public offering of common stock of the Issuer.

F2 · ownership.nature: The shares are directly held by Alta Partners NextGen Fund I, L.P. ("APNG I"). Alta Partners NextGen Fund I Management, LLC ("APNG I Management") is the general partner of APNG I. The Reporting Person is one of three managing directors of APNG I Management and, as such, has voting and investment control with respect to the shares held by APNG I. The Reporting Person disclaims beneficial ownership of all shares held by APNG I, except to the extent of his pecuniary interest therein.

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June 30, 2022 Filed Jul 1, 2022 20:12 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GrantStock Option (Right to Buy) · Derivative 6,800 $0.00 Strike: $65.66 $0.00
Disclosure

SEC source: 0001711279-22-000038 · wf-form4_165670631803960.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,800

Underlying: Common Stock · 6,800 shares

Expires 2032-06-30

F1 · derivative.exercise_date: The options were awarded on June 30, 2022 and vest in equal monthly tranches over a one-year period.

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May 25, 2022 Filed May 27, 2022 16:16 UTC Allakos Inc. ALLK · Entity 79644 GrantStock Option (Right to buy) · Derivative 99,590 $0.00 Strike: $2.62 $0.00
Disclosure

SEC source: 0001209191-22-032520 · doc4.xml · derivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,590

Underlying: Common Stock · 99,590 shares

Expires 2032-05-25

F1 · derivative.exercise_date: The option vests as to 100% of the shares on the earlier of (i) the one-year anniversary of the date of grant or (ii) the date of the Issuer's next Annual Meeting of stockholders that occurs following the grant, subject to the Reporting Person continuing as a service provider through each such date.

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December 30, 2021 Filed Feb 2, 2022 21:38 UTC Krystal Biotech, Inc. KRYS · Entity 3500 GiftCommon Stock 34,000 $0.00 $0.00
Disclosure

SEC source: 0001062993-22-002225 · form5.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 232,362

F1 · shares: The Reporting Person transferred these shares of common stock to a charitable trust, over which the Reporting Person has no pecuniary interest or investment control.

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December 10, 2021 Filed Dec 14, 2021 21:11 UTC Krystal Biotech, Inc. KRYS · Entity 3500 SaleCommon Stock 100,000 $70.50 $7,050,000.00
Disclosure

SEC source: 0000899243-21-048122 · doc4.xml · nonDerivative · entry 1

JANNEY DANIEL · CIK 0001198325 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Alta Bioequities L.P

Disclosed balance after: 266,362

F1 · shares: On December 3, 2021, Krystal Biotech, Inc. (the "Company"), closed the previously announced underwritten public offering of 2,666,667 shares of its common stock, at a public offering price of $75.00 per share. The Company and certain selling stockholders granted the underwriters a 30-day option to purchase up to an additional 400,000 shares of the Company's common stock offered in the public offering, which includes up to 200,000 shares from the selling stockholders. The underwriters exercised the option and on December 10, 2021, purchased the 400,000 shares of the Company's common stock, including 100,000 shares of the Company's common stock from Alta Bioequities, L.P., a selling stockholder.

F2 · ownership.nature: Alta Bioequities Management, LLC is the general partner of Alta Bioequities, L.P. and may be deemed to have sole voting and investment power over the shares beneficially owned by Alta Bioequities, L.P. The Reporting Person is the Managing Director of Alta Bioequities Management, LLC and may be deemed to have voting and investment power over the shares owned by Alta Bioequities, L.P.

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September 17, 2021 Filed Sep 17, 2021 20:47 UTC Tyra Biosciences, Inc. TYRA · Entity 4680 ConversionSeries B Preferred Stock · Derivative 255,160 $0.00 $0.00
Disclosure

SEC source: 0000899243-21-036429 · doc4.xml · derivative · entry 4

Alta Partners NextGen Fund II Management, LLC · CIK 0001881002 · 10% owner

Alta Partners NextGen Fund II, L.P. · CIK 0001768658 · 10% owner

Hudson Peter A · CIK 0001674884 · 10% owner

JANNEY DANIEL · CIK 0001198325 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 662,752 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F1 · derivative.exercise_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F1 · derivative.expiration_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

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September 17, 2021 Filed Sep 17, 2021 20:47 UTC Tyra Biosciences, Inc. TYRA · Entity 4680 ConversionSeries A Preferred Stock · Derivative 1,212,122 $0.00 $0.00
Disclosure

SEC source: 0000899243-21-036429 · doc4.xml · derivative · entry 3

Alta Partners NextGen Fund II Management, LLC · CIK 0001881002 · 10% owner

Alta Partners NextGen Fund II, L.P. · CIK 0001768658 · 10% owner

Hudson Peter A · CIK 0001674884 · 10% owner

JANNEY DANIEL · CIK 0001198325 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 3,148,365 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F1 · derivative.exercise_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F1 · derivative.expiration_date: On September 17, 2021, each share of Series A Preferred Stock and each share of Series B Preferred Stock converted into Common Stock of the Issuer at a ratio of 1-for-2.5974 without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date. As a result of the Issuer's initial public offering, the reporting persons are no longer 10% owners of the Issuer's common stock and are, therefore, no longer subject to Section 16 in connection with their transactions in the equity securities of the Issuer.

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

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September 17, 2021 Filed Sep 17, 2021 20:47 UTC Tyra Biosciences, Inc. TYRA · Entity 4680 PurchaseCommon Stock 156,250 $16.00 $2,500,000.00
Disclosure

SEC source: 0000899243-21-036429 · doc4.xml · nonDerivative · entry 2

Alta Partners NextGen Fund II Management, LLC · CIK 0001881002 · 10% owner

Alta Partners NextGen Fund II, L.P. · CIK 0001768658 · 10% owner

Hudson Peter A · CIK 0001674884 · 10% owner

JANNEY DANIEL · CIK 0001198325 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 4,080,296

F2 · ownership.nature: These securities are held directly by Alta Partners NextGen Fund II, L.P. (the "APNG II"). The shares directly held by APNG II are indirectly held by Alta Partners NextGen Fund II Management, LLC ("APNG II Management"), which is the general partner of APNG II. The individual managing directors of APNG II Management are Robert More, Peter Hudson and Daniel Janney. The managing directors of APNG II Management exercise shared voting and investment control with respect to the shares held by APNG II. APNG II Management, Mr. Hudson and Mr. Janney disclaim beneficial ownership of all shares held by APNG II, except to the extent of its or their respective pecuniary interests therein. Mr. More is a director of the Issuer and files separate Section 16 reports.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.