IRD

SEC source: 0002042266-26-000002 · primary_doc.xml · nonDerivative · entry 1

Foundation Fighting Blindness Retinal Degeneration Fund · CIK 0002042266 · Director · See Remarks

Foundation Fighting Blindness, Inc. · CIK 0002042532 · Director · See Remarks

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,236,171

F1 · price: This transaction was executed in multiple trades at prices ranging from $4.95 to $5.29. The price reported in Column 4 is a weighted average price. The Reporting Persons hereby undertake to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transactions were effected.

F2 · ownership.direct: Foundation Fighting Blindness, Inc. ("FFB") is the sole member of Foundation Fighting Blindness Retinal Degeneration Fund ("RDF") and may be deemed to beneficially own the securities owned directly by RDF. RDF has the power to vote and dispose of any securities directly owned by RDF. RDF's board of directors makes voting and investment decisions regarding securities held by RDF, subject to certain approval rights of the board of directors of FFB with respect to transactions exceeding a certain threshold.

SEC source: 0001140361-26-036347 · form4.xml · derivative · entry 3

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 392,157 shares

Expires 2030-03-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The Warrant was immediately exercisable upon its acquisition on March 24, 2025, subject to the Issuer's right to call the Warrant at any time beginning 30 days following the release of the Issuer's OPGx-BEST1 DUO-1001 Cohort 1 data upon achievement of (i) a volume weighted average price of the Issuer's Common Stock for 30 consecutive trading days of over $1.725 per share and (ii) the trading average daily volume for such 30 day period exceeding $150,000 per trading day.

SEC source: 0001140361-26-036347 · form4.xml · nonDerivative · entry 2

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,048,485

F1 · kind: The Reporting Person paid the exercise price of the Warrant on a cashless basis. The Issuer withheld 75,541 shares, calculated in accordance with the terms of the Warrant, to pay the exercise price and issued the remaining 316,616 shares to the Reporting Person.

SEC source: 0001140361-26-036347 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,124,026

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001140361-26-035913 · form4.xml · derivative · entry 3

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 784,314 shares

Expires 2030-03-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The Warrant was immediately exercisable upon its acquisition on March 24, 2025, subject to the Issuer's right to call the Warrant at any time beginning 30 days following the release of the Issuer's OPGx-BEST1 DUO-1001 Cohort 1 data upon achievement of (i) a volume weighted average price of the Issuer's Common Stock for 30 consecutive trading days of over $1.725 per share and (ii) the trading average daily volume for such 30 day period exceeding $150,000 per trading day.

SEC source: 0001140361-26-035913 · form4.xml · nonDerivative · entry 1

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,800,111

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: In conjunction with the exercise of the Warrant reported herein, the Reporting Person entered into a Lock-Up Agreement with the Issuer dated September 6, 2026 (the "Lock-Up Agreement"). Pursuant to the Lock-Up Agreement, among other terms, the Reporting Person agreed that, without the prior written consent of the Issuer, during the period beginning on September 6, 2026 and ending at the close of business 180 days after the issuance of the shares of Common Stock underlying the Warrant, the Reporting Person will not transfer or dispose of, directly or indirectly, any shares of Common Stock, or any securities convertible into or exercisable or exchangeable for Common Stock (including, without limitation, Common Stock or such other securities which may be deemed to be beneficially owned by the Reporting Person and securities which may be issued upon exercise of a stock option or warrant), as further described in the Lock-Up Agreement and subject to certain exclusions described therein.

SEC source: 0001140361-26-035912 · form4.xml · nonDerivative · entry 1

Gagnon Robert E. · CIK 0001504983 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 556,375

F1 · kind: A portion of the shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Issuer, to satisfy tax withholding obligations that arose in connection with the vesting and settlement of restricted stock units, and the remainder of the shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on April 30, 2026. The Rule 10b5-1 trading plan is a pre-arranged written trading plan pursuant to which shares of the Issuer's common stock are sold automatically based on a predetermined formula that was established by the Reporting Person at a time when the Reporting Person was not aware of any material nonpublic information about the Issuer.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $4.29 to $4.79, inclusive. The Reporting Person undertakes to provide the Issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-003353 · form4.xml · nonDerivative · entry 1

SCHACHLE JOSEPH K · CIK 0001145914 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 291,440

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-26-003354 · form4.xml · nonDerivative · entry 1

YERXA BENJAMIN R · CIK 0001145910 · Director · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 704,106

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-26-003352 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,731,869

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $2.9009 to $3.025, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-003351 · form4.xml · nonDerivative · entry 1

Gagnon Robert E. · CIK 0001504983 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 584,375

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $2.9006 to $3.025, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0002042266-26-000001 · primary_doc.xml · nonDerivative · entry 1

Foundation Fighting Blindness Retinal Degeneration Fund · CIK 0002042266 · Director · See Remarks

Foundation Fighting Blindness, Inc. · CIK 0002042532 · Director · See Remarks

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,792,171

F1 · ownership.direct: Foundation Fighting Blindness, Inc. ("FFB") is the sole member of Foundation Fighting Blindness Retinal Degeneration Fund ("RDF") and may be deemed to beneficially own the securities owned directly by RDF. RDF has the power to vote and dispose of any securities directly owned by RDF. RDF's board of directors makes voting and investment decisions regarding securities held by RDF, subject to certain approval rights of the board of directors of FFB with respect to transactions exceeding a certain threshold.

SEC source: 0000905148-26-001866 · form4.xml · nonDerivative · entry 1

SCHACHLE JOSEPH K · CIK 0001145914 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 296,084

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-26-001867 · form4.xml · nonDerivative · entry 1

YERXA BENJAMIN R · CIK 0001145910 · Director · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 711,535

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.2314 to $5.2413, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-001863 · form4.xml · nonDerivative · entry 1

Jayagopal Ashwath · CIK 0002008983 · Chief Scientific & Dev. Ofc.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 509,233

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.18 to $5.21, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-001864 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,741,344

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-26-001865 · form4.xml · nonDerivative · entry 1

Zaremba Rabourn Amy · CIK 0001832343 · Head of Fin. Quality Assurance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 188,671

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.2038 to $5.2051, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-001862 · form4.xml · nonDerivative · entry 1

Gagnon Robert E. · CIK 0001504983 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 592,158

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.1828 to $5.1901, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-001782 · form4.xml · nonDerivative · entry 1

Bennett Jean · CIK 0001872219 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 259,019

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001787 · form4.xml · nonDerivative · entry 1

MANUSO JAMES S J · CIK 0001236365 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 317,318

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001785 · form4.xml · nonDerivative · entry 1

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,015,797

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001788 · form4.xml · nonDerivative · entry 1

Rodgers Richard J · CIK 0001313397 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 343,022

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001786 · form4.xml · nonDerivative · entry 1

Graves Adrienne L · CIK 0001326192 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 127,514

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001781 · form4.xml · nonDerivative · entry 1

Ainsworth Sean · CIK 0001830296 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 321,692

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001784 · form4.xml · nonDerivative · entry 1

Benton Susan · CIK 0001373649 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 243,894

F1 · shares: Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-001384 · form4.xml · nonDerivative · entry 1

SCHACHLE JOSEPH K · CIK 0001145914 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,781

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-26-001380 · form4.xml · nonDerivative · entry 1

Jayagopal Ashwath · CIK 0002008983 · Chief Scientific & Dev. Ofc.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 516,775

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.11 to $5.1301, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-001381 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,750,855

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

F2 · price: The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.21 to $5.215, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000905148-26-001382 · form4.xml · nonDerivative · entry 1

Zaremba Rabourn Amy · CIK 0001832343 · Head of Fin. Quality Assurance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 190,312

F1 · kind: The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

SEC source: 0000905148-26-000904 · form4.xml · nonDerivative · entry 1

Jayagopal Ashwath · CIK 0002008983 · Chief Scientific & Dev. Ofc.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 520,494

F1 · kind: The Issuer withheld the shares reported on this line to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. Not an open market sale of securities.

SEC source: 0000905148-26-000358 · form4.xml · nonDerivative · entry 1

SCHACHLE JOSEPH K · CIK 0001145914 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 304,500

F1 · shares: Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service.

SEC source: 0000905148-26-000359 · form4.xml · nonDerivative · entry 1

YERXA BENJAMIN R · CIK 0001145910 · Director · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 719,005

F1 · shares: Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service.

SEC source: 0000905148-26-000355 · form4.xml · nonDerivative · entry 1

Jayagopal Ashwath · CIK 0002008983 · Chief Scientific & Dev. Ofc.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 525,807

F1 · shares: Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service.

SEC source: 0000905148-26-000356 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,775,293

F1 · shares: Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service.

SEC source: 0000905148-26-000357 · form4.xml · nonDerivative · entry 1

Zaremba Rabourn Amy · CIK 0001832343 · Head of Fin. Quality Assurance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 193,128

F1 · shares: Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service.

SEC source: 0000905148-26-000354 · form4.xml · nonDerivative · entry 1

Gagnon Robert E. · CIK 0001504983 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 600,000

F1 · shares: Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service.

SEC source: 0000905148-26-000282 · form4.xml · nonDerivative · entry 1

Zaremba Rabourn Amy · CIK 0001832343 · Head of Fin. Quality Assurance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,628

F1 · kind: The Issuer withheld the shares reported on this line to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. Not an open market sale of securities.

SEC source: 0000905148-26-000164 · form4.xml · nonDerivative · entry 1

Zaremba Rabourn Amy · CIK 0001832343 · Head of Fin. Quality Assurance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 110,018

F1 · kind: The Issuer withheld the shares reported on this line to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. Not an open market sale of securities.

SEC source: 0000905148-26-000088 · form4.xml · nonDerivative · entry 1

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,991,430

F1 · shares: Represents a grant of restricted stock units which vest on December 29, 2026, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-26-000028 · form4.xml · nonDerivative · entry 1

Bennett Jean · CIK 0001872219 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 234,652

F1 · price: The Reporting Person was granted shares of common stock in lieu of cash for board services for 2026. The number of shares was determined by dividing (A) the aggregate amount of the retainer to be earned for board services for such period, by (B) the average fair market value of a share of common stock the day prior to the grant date (rounded down to the nearest whole share). The average fair market value was $1.99 per share, the average of the high and low price of the common stock, the day prior to the grant date.

SEC source: 0000905148-26-000036 · form4.xml · nonDerivative · entry 1

MANUSO JAMES S J · CIK 0001236365 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 292,951

F1 · price: The Reporting Person was granted shares of common stock in lieu of cash for board services for 2026. The number of shares was determined by dividing (A) the aggregate amount of the retainer to be earned for board services for such period, by (B) the average fair market value of a share of common stock the day prior to the grant date (rounded down to the nearest whole share). The average fair market value was $1.99 per share, the average of the high and low price of the common stock, the day prior to the grant date.

SEC source: 0000905148-26-000031 · form4.xml · nonDerivative · entry 1

Graves Adrienne L · CIK 0001326192 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 103,147

F1 · price: The Reporting Person was granted shares of common stock in lieu of cash for board services for 2026. The number of shares was determined by dividing (A) the aggregate amount of the retainer to be earned for board services for such period, by (B) the average fair market value of a share of common stock the day prior to the grant date (rounded down to the nearest whole share). The average fair market value was $1.99 per share, the average of the high and low price of the common stock, the day prior to the grant date.

SEC source: 0000905148-26-000027 · form4.xml · nonDerivative · entry 1

Ainsworth Sean · CIK 0001830296 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 297,325

F1 · price: The Reporting Person was granted shares of common stock in lieu of cash for board services for 2026. The number of shares was determined by dividing (A) the aggregate amount of the retainer to be earned for board services for such period, by (B) the average fair market value of a share of common stock the day prior to the grant date (rounded down to the nearest whole share). The average fair market value was $1.99 per share, the average of the high and low price of the common stock, the day prior to the grant date.

SEC source: 0000905148-25-004511 · form4.xml · nonDerivative · entry 3

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,924,430

F4 · shares: Represents a grant of restricted stock units ("RSUs") which vest on December 29, 2026, subject to the Reporting Person's continuing service through the vesting date.

F5 · shares: On December 31, 2025, the Issuer's Board of Directors also approved a grant to the Reporting Person, effective January 6, 2026, of an additional 67,000 RSUs which vest on December 29, 2026, subject to the Reporting Person's continuing service through the vesting date.

SEC source: 0000905148-25-004511 · form4.xml · nonDerivative · entry 2

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Garret Gallagher - Custodian UTMA/UGMA

Disclosed balance after: 83,000

F2 · price: The price in column 4 represents the weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.9476 to $1.98, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

F3 · ownership.nature: These securities are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein, if any, and the filing of this report is not an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-25-004511 · form4.xml · nonDerivative · entry 1

Gallagher Cam · CIK 0001557832 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,891,430

F1 · price: The price in column 4 represents the weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.945 to $1.98, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

SEC source: 0002042266-25-000003 · primary_doc.xml · nonDerivative · entry 1

Foundation Fighting Blindness Retinal Degeneration Fund · CIK 0002042266 · Director · See Remarks

Foundation Fighting Blindness, Inc. · CIK 0002042532 · Director · See Remarks

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,492,171

F1 · ownership.direct: Foundation Fighting Blindness, Inc. ("FFB") is the sole member of Foundation Fighting Blindness Retinal Degeneration Fund ("RDF") and may be deemed to beneficially own the securities owned directly by RDF. RDF has the power to vote and dispose of any securities directly owned by RDF. RDF's board of directors makes voting and investment decisions regarding securities held by RDF, subject to certain approval rights of the board of directors of FFB with respect to transactions exceeding a certain threshold.

SEC source: 0000905148-25-003767 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,291,654

SEC source: 0000905148-25-003777 · form4.xml · nonDerivative · entry 1

Magrath George · CIK 0001999390 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,291,654

F1 · kind: The Issuer withheld the shares reported on this line to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. Not an open market sale of securities.

SEC source: 0000905148-25-003670 · form4.xml · nonDerivative · entry 1

YERXA BENJAMIN R · CIK 0001145910 · Director · President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 319,005