INSM

SEC source: 0001628280-24-000693 · wk-form4_1704493778.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 373,538

F3 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F4 · price: This is the weighted average sales price representing 6,979 shares sold at prices ranging from $29.24 to $29.26 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-24-000692 · wk-form4_1704493741.xml · nonDerivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 117,525

F3 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-24-000690 · wk-form4_1704493596.xml · nonDerivative · entry 2

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 161,183

F3 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-24-000698 · wk-form4_1704494003.xml · derivative · entry 6

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 63,560

Underlying: Common Stock · 63,560 shares

Expires 2034-01-04

F8 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000698 · wk-form4_1704494003.xml · nonDerivative · entry 3

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 116,857

F4 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F5 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

SEC source: 0001628280-24-000697 · wk-form4_1704493968.xml · derivative · entry 3

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,260

Underlying: Common Stock · 58,260 shares

Expires 2034-01-04

F5 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000697 · wk-form4_1704493968.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,364

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

F3 · balance_after: Includes 422 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-24-000696 · wk-form4_1704493919.xml · derivative · entry 3

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,260

Underlying: Common Stock · 58,260 shares

Expires 2034-01-04

F5 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000696 · wk-form4_1704493919.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,606

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

F3 · balance_after: Includes 257 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-24-000693 · wk-form4_1704493778.xml · derivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 186,970

Underlying: Common Stock · 186,970 shares

Expires 2034-01-04

F5 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000693 · wk-form4_1704493778.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 380,517

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

SEC source: 0001628280-24-000692 · wk-form4_1704493741.xml · derivative · entry 3

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,560

Underlying: Common Stock · 63,560 shares

Expires 2034-01-04

F4 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000692 · wk-form4_1704493741.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 118,911

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

SEC source: 0001628280-24-000691 · wk-form4_1704493648.xml · derivative · entry 2

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,560

Underlying: Common Stock · 63,560 shares

Expires 2034-01-04

F4 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000691 · wk-form4_1704493648.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 118,548

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

F3 · balance_after: Includes 434 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-24-000690 · wk-form4_1704493596.xml · derivative · entry 3

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 63,560

Underlying: Common Stock · 63,560 shares

Expires 2034-01-04

F4 · derivative.exercise_date: Stock options granted under the Company's Amended and Restated 2019 Incentive Plan. The options become exercisable based on the following vesting schedule: twenty five percent (25%) vest on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vest on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000690 · wk-form4_1704493596.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 164,225

F1 · shares: Represents Restricted Stock Units, each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan. The Restricted Stock Units vest and become available as follows: twenty five (25%) percent on each anniversary of the date of grant through the fourth anniversary date of the date of the grant.

F2 · price: Each Restricted Stock Unit was received as a grant on January 4, 2024, for no consideration.

SEC source: 0001628280-24-000698 · wk-form4_1704494003.xml · derivative · entry 5

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 20,071 shares

Expires 2024-02-10

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: Stock options granted under the Company's 2013 Incentive Plan. The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary date of the date of grant.

SEC source: 0001628280-24-000698 · wk-form4_1704494003.xml · nonDerivative · entry 2

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 103,984

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 20,071 shares sold at prices ranging from $28.915 to $29.39 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-24-000698 · wk-form4_1704494003.xml · nonDerivative · entry 1

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 124,055

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 1,303 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-24-000052 · wk-form4_1704229471.xml · derivative · entry 3

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 503

Underlying: Common Stock · 22,288 shares

Expires 2024-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · derivative.exercise_date: Stock options granted under the Company's 2013 Incentive Plan. The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

SEC source: 0001628280-24-000052 · wk-form4_1704229471.xml · nonDerivative · entry 2

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 94,549

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-24-000052 · wk-form4_1704229471.xml · nonDerivative · entry 1

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 116,837

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 1,024 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-23-042631 · wk-form4_1703279055.xml · derivative · entry 3

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 122,680

Underlying: Common Stock · 28,310 shares

Expires 2030-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · derivative.exercise_date: In connection with the appointment of Dr. Flammer as the Company's Chief Medical Officer, the Company granted Dr. Flammer an option to purchase a total of 150,990 shares of the Company's common stock. The option becomes exercisable based on the following vesting schedule: twenty-five percent (25%) vest on the first anniversary of the date of grant and twelve and one-half percent (12.5%) vest on each six month anniversary date thereafter through the fourth anniversary of the date of grant, subject to Dr. Flammer's continued employment with the Company on each vesting date.

SEC source: 0001628280-23-042631 · wk-form4_1703279055.xml · nonDerivative · entry 2

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,038

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-23-042631 · wk-form4_1703279055.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 134,348

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

SEC source: 0001628280-23-042628 · wk-form4_1703279004.xml · nonDerivative · entry 1

Bonstein Sara · CIK 0001604019 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,241

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · balance_after: Includes 821 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · derivative · entry 17

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By ARTICLE 4 TRUST UNDER KATIE PROCTER DYNASTY TRUST

Disclosed balance after: 0

Underlying: Common Stock · 57,000 shares

Expires 2023-10-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable and were scheduled to expire on October 31, 2023.

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · derivative · entry 16

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A 11/1/2020

Disclosed balance after: 0

Underlying: Common Stock · 500 shares

Expires 2023-10-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable and were scheduled to expire on October 31, 2023.

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · derivative · entry 15

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A 11/1/2020

Disclosed balance after: 500

Underlying: Common Stock · 55,000 shares

Expires 2023-10-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F9 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: twenty five percent (25%) vested on the first anniversary of the grant date and an additional twelve and one half percent (12.5%) vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable and were scheduled to expire on October 31, 2023.

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 13

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · ownership.nature: By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 12

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 234,251

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · ownership.nature: By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · price: This is the weighted average sales price representing 1,323 shares sold at prices ranging from $24.83 to $25.40 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F5 · ownership.nature: By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 235,247

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · ownership.nature: By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 233,924

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 55,350 shares sold at prices ranging from $23.65 to $24.63 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F5 · ownership.nature: By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 289,274

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · ownership.nature: By ARTICLE 4 KATIE PROCTER DYNASTY TRUST

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 0

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 315

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 0

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 1,322 shares sold at prices ranging from $24.83 to $25.40 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 1,322

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 0

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 53,363 shares sold at prices ranging from $23.68 to $24.60 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001628280-23-035712 · wk-form4_1698782649.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Indirect · Indirect

Disclosed balance after: 53,363

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · ownership.nature: By ARTICLE 4 TRUST UNDER WILLIAM LEWIS FAMILY LEGACY TRUST U/A11/1/2020

SEC source: 0001140361-23-034422 · form4.xml · nonDerivative · entry 1

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,142

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · balance_after: Includes 800 shares acquired through the Company's 2018 Employee Stock Purchase Plan.

SEC source: 0001628280-23-022221 · wf-form4_168685960186874.xml · nonDerivative · entry 1

Flammer Martina M.D. · CIK 0001796960 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 106,038

F1 · kind: The reported sale occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 15, 2023.

F2 · price: This is the weighted average sales price representing 8,868 shares sold at prices ranging from $19.23 to $19.37 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-022218 · wf-form4_168685949558953.xml · nonDerivative · entry 1

Adsett Roger · CIK 0001685904 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 151,352

F1 · kind: The reported sale occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 15, 2023.

F2 · price: This is the weighted average sales price representing 8,981 shares sold at prices ranging from $19.23 to $19.46 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-019941 · wf-form4_168513149079505.xml · nonDerivative · entry 1

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 102,681

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

F2 · price: This is the weighted average sales price representing 3,366 shares sold at prices ranging from $18.93 to $18.95 per share. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

SEC source: 0001628280-23-018700 · wf-form4_168435453768194.xml · nonDerivative · entry 3

Wise John Drayton · CIK 0001930805 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,047

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018691 · wf-form4_168435436955097.xml · nonDerivative · entry 3

Schaeffer Orlov S Nicole · CIK 0001401017 · Chief People Strategy Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 93,525

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

SEC source: 0001628280-23-018696 · wf-form4_168435443742523.xml · nonDerivative · entry 3

Smith Michael Alexander · CIK 0001870278 · General Counsel, Senior VP

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,082

F1 · kind: Shares sold to satisfy withholding tax obligations upon the vesting of Restricted Stock Units and to cover related broker fees.