ERAS

SEC source: 0001193125-26-346924 · ownership.xml · derivative · entry 1

Fuchs Charles S. · CIK 0001719576 · President, R&D

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,300,000

Underlying: Common Stock · 1,300,000 shares

Expires 2036-08-09

F1 · shares: The reported option award was granted in connection with the Reporting Person's commencement of employment. Of the total option award, 21,480 shares were granted under the Issuer's 2021 Incentive Award Plan, with a portion intended to qualify as an incentive stock option under Section 422 of the Internal Revenue Code to the extent permitted by law. The remaining 1,278,520 shares were granted as a nonqualified stock option under the Issuer's 2026 Employment Inducement Incentive Award Plan.

F2 · derivative.exercise_date: The reported option award vests as follows: 25% of the shares subject to the option will vest on the first anniversary of the date of grant, and the remaining 75% of the shares will vest in 36 substantially equal monthly installments thereafter, subject to the Reporting Person's continued service with the Issuer through each applicable vesting date.

SEC source: 0001193125-26-288910 · ownership.xml · derivative · entry 1

Start Valerie Denise Harding · CIK 0001652037 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,888

Underlying: Common Stock · 29,888 shares

Expires 2036-06-26

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 26, 2027, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0001193125-26-288908 · ownership.xml · derivative · entry 1

LIU JEAN I · CIK 0001241357 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,888

Underlying: Common Stock · 29,888 shares

Expires 2036-06-26

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 26, 2027, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0001193125-26-288906 · ownership.xml · derivative · entry 1

Multani Pratik S · CIK 0001586894 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,888

Underlying: Common Stock · 29,888 shares

Expires 2036-06-26

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 26, 2027, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0001193125-26-288905 · ownership.xml · derivative · entry 1

Casdin Alexander W. · CIK 0001455228 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,888

Underlying: Common Stock · 29,888 shares

Expires 2036-06-26

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 26, 2027, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0001193125-26-288903 · ownership.xml · derivative · entry 1

Hambleton Julie · CIK 0001578771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,888

Underlying: Common Stock · 29,888 shares

Expires 2036-06-26

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 26, 2027, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0001193125-26-288902 · ownership.xml · derivative · entry 1

Bristol James Arthur · CIK 0001715153 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,888

Underlying: Common Stock · 29,888 shares

Expires 2036-06-26

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 26, 2027, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0001193125-26-141395 · ownership.xml · derivative · entry 3

Garner Ebun · CIK 0001364554 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 280,000

Underlying: Common Stock · 80,000 shares

Expires 2034-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

F3 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 1, 2024, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001193125-26-141395 · ownership.xml · nonDerivative · entry 2

Garner Ebun · CIK 0001364554 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,076

F1 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

F2 · price: This represents a weighted-average price. These shares were sold in multiple transactions at prices ranging from $16.11 to $16.58. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001193125-26-141395 · ownership.xml · nonDerivative · entry 1

Garner Ebun · CIK 0001364554 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,076

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

SEC source: 0001193125-26-095181 · ownership.xml · nonDerivative · entry 2

Morris Shannon · CIK 0001973527 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

F2 · price: This represents a weighted-average price. These shares were sold in multiple transactions at prices ranging from $15.00 to $15.10. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001193125-26-095181 · ownership.xml · nonDerivative · entry 1

Morris Shannon · CIK 0001973527 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

SEC source: 0001193125-26-030624 · ownership.xml · derivative · entry 2

Chacko David M. · CIK 0001871801 · CFO and CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 640,000

Underlying: Common Stock · 640,000 shares

Expires 2036-01-29

F3 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly on the 29th day of each month (or the last day of February), starting in February 2026, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0001193125-26-030626 · ownership.xml · derivative · entry 1

Lim Jonathan E · CIK 0001283290 · Director · Chairman & CEO · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000,000

Underlying: Common Stock · 2,000,000 shares

Expires 2036-01-29

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly on the 29th day of each month (or the last day of February), starting in February 2026, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0001193125-26-030619 · ownership.xml · derivative · entry 1

Morris Shannon · CIK 0001973527 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 625,000

Underlying: Common Stock · 625,000 shares

Expires 2036-01-29

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly on the 29th day of each month (or the last day of February), starting in February 2026, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0001193125-26-030617 · ownership.xml · derivative · entry 1

Varney Michael David · CIK 0001638647 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,000

Underlying: Common Stock · 96,000 shares

Expires 2036-01-29

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly on the 29th day of each month (or the last day of February), starting in February 2026, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0001193125-26-030615 · ownership.xml · derivative · entry 1

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 560,000

Underlying: Common Stock · 560,000 shares

Expires 2036-01-29

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly on the 29th day of each month (or the last day of February), starting in February 2026, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0001193125-26-008076 · ownership.xml · nonDerivative · entry 3

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,076

F2 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

F3 · price: This represents a weighted-average price. These shares were sold in multiple transactions at prices ranging from $5.50 to $5.80. The Reporting Person undertakes to provide the Issuer, any securityholder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001193125-26-008076 · ownership.xml · nonDerivative · entry 2

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,076

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

SEC source: 0001193125-26-001611 · ownership.xml · derivative · entry 1

Bristol James Arthur · CIK 0001715153 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,762

Underlying: Common Stock · 37,762 shares

Expires 2036-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2026 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2026.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0001193125-26-001610 · ownership.xml · derivative · entry 1

LIU JEAN I · CIK 0001241357 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,617

Underlying: Common Stock · 20,617 shares

Expires 2036-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2026 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2026.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0001193125-26-001609 · ownership.xml · derivative · entry 1

Multani Pratik S · CIK 0001586894 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,532

Underlying: Common Stock · 19,532 shares

Expires 2036-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2026 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2026.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0001193125-26-001608 · ownership.xml · derivative · entry 1

Start Valerie Denise Harding · CIK 0001652037 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,306

Underlying: Common Stock · 24,306 shares

Expires 2036-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2026 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2026.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0001193125-26-001606 · ownership.xml · derivative · entry 1

Casdin Alexander W. · CIK 0001455228 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,872

Underlying: Common Stock · 23,872 shares

Expires 2036-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2026 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2026.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0001193125-26-008076 · ownership.xml · nonDerivative · entry 1

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,076

F1 · price: The purchase price was calculated in accordance with the Issuer's 2021 Employee Stock Purchase Plan.

SEC source: 0001193125-26-030624 · ownership.xml · nonDerivative · entry 1

Chacko David M. · CIK 0001871801 · CFO and CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 279,980

F1 · kind: Shares purchased under the Company's 2021 Employee Stock Purchase Plan

F2 · price: The purchase price was calculated in accordance with the issuer's 2021 Employee Stock Purchase Plan.

SEC source: 0000950170-25-090426 · ownership.xml · derivative · entry 1

Varney Michael David · CIK 0001638647 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-090423 · ownership.xml · derivative · entry 1

Hambleton Julie · CIK 0001578771 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-090424 · ownership.xml · derivative · entry 1

LIU JEAN I · CIK 0001241357 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-090422 · ownership.xml · derivative · entry 1

Start Valerie Denise Harding · CIK 0001652037 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-090418 · ownership.xml · derivative · entry 1

Bristol James Arthur · CIK 0001715153 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-090420 · ownership.xml · derivative · entry 1

Multani Pratik S · CIK 0001586894 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-090415 · ownership.xml · derivative · entry 1

Casdin Alexander W. · CIK 0001455228 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 120,000

Underlying: Common Stock · 120,000 shares

Expires 2035-06-23

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 24, 2026, subject to the Reporting Person's continuous service to the Issuer on such vesting date.

SEC source: 0000950170-25-080941 · ownership.xml · nonDerivative · entry 2

Multani Pratik S · CIK 0001586894 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Multani Family Trust U/A DTD 08/10/2006

Disclosed balance after: 6,200

F1 · acquired: The Reporting Person transferred 6,200 shares of common stock to a family trust for no consideration, for estate planning purposes. The Reporting Person holds all voting and dispositive power with respect to the securities held by the trust and remains the beneficial owner of such securities.

SEC source: 0000950170-25-080941 · ownership.xml · nonDerivative · entry 1

Multani Pratik S · CIK 0001586894 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 166,666

F1 · acquired: The Reporting Person transferred 6,200 shares of common stock to a family trust for no consideration, for estate planning purposes. The Reporting Person holds all voting and dispositive power with respect to the securities held by the trust and remains the beneficial owner of such securities.

SEC source: 0001193125-26-095181 · ownership.xml · derivative · entry 3

Morris Shannon · CIK 0001973527 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 515,800

Underlying: Common Stock · 20,000 shares

Expires 2034-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

F3 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 1, 2024, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0000950170-25-021831 · ownership.xml · derivative · entry 1

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2035-02-12

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 13, 2025, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0000950170-25-014197 · ownership.xml · derivative · entry 3

Chacko David M. · CIK 0001871801 · CFO and CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 800,000

Underlying: Common Stock · 800,000 shares

Expires 2035-02-02

F4 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 1, 2025, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0000950170-25-014194 · ownership.xml · derivative · entry 3

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 700,000

Underlying: Common Stock · 700,000 shares

Expires 2035-02-02

F4 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 1, 2025, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0000950170-25-014195 · ownership.xml · derivative · entry 1

Morris Shannon · CIK 0001973527 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 780,000

Underlying: Common Stock · 780,000 shares

Expires 2035-02-02

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 1, 2025, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0000950170-25-014192 · ownership.xml · derivative · entry 1

Lim Jonathan E · CIK 0001283290 · Director · Chairman & CEO · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,500,000

Underlying: Common Stock · 2,500,000 shares

Expires 2035-02-02

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on February 1, 2025, subject to the Reporting Person's continuous service to the issuer on each such vesting date.

SEC source: 0001193125-26-008076 · ownership.xml · derivative · entry 4

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 360,000

Underlying: Common Stock · 120,000 shares

Expires 2034-02-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: The exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 30, 2024.

F4 · derivative.exercise_date: The shares subject to this option award are fully vested and exercisable as of the date hereof.

SEC source: 0000950170-25-000639 · ownership.xml · derivative · entry 1

Casdin Alexander W. · CIK 0001455228 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,877

Underlying: Common Stock · 28,877 shares

Expires 2035-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2025 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2025.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0000950170-25-000637 · ownership.xml · derivative · entry 1

LIU JEAN I · CIK 0001241357 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,939

Underlying: Common Stock · 24,939 shares

Expires 2035-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2025 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2025.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0000950170-25-000635 · ownership.xml · derivative · entry 1

Start Valerie Denise Harding · CIK 0001652037 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,402

Underlying: Common Stock · 29,402 shares

Expires 2035-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2025 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2025.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0000950170-25-000630 · ownership.xml · derivative · entry 1

Bristol James Arthur · CIK 0001715153 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,678

Underlying: Common Stock · 45,678 shares

Expires 2035-01-01

F1 · security: At the election of the filing person the option grant was issued in lieu of the cash compensation payable to such person in 2025 in connection with each position on the issuer's board of directors and its committees for which such person is anticipated to serve in 2025.

F2 · derivative.exercise_date: The option will vest and become exercisable in monthly, cumulative 1/12 increments beginning one month from the date of grant, subject to such person continuing to serve on the issuer's board of directors through the applicable vesting date.

SEC source: 0000950170-25-014197 · ownership.xml · nonDerivative · entry 2

Chacko David M. · CIK 0001871801 · CFO and CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 262,187

F1 · kind: Shares purchased under the Company's 2021 Employee Stock Purchase Plan

F2 · price: The purchase price was calculated in accordance with the issuer's 2021 Employee Stock Purchase Plan.

F3 · balance_after: Reflects all transactions reported under this report.

SEC source: 0000950170-25-014194 · ownership.xml · nonDerivative · entry 2

Garner Ebun · CIK 0001364554 · General Counsel & Corp. Sec.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,174

F1 · kind: Shares purchased under the Company's 2021 Employee Stock Purchase Plan

F2 · price: The purchase price was calculated in accordance with the issuer's 2021 Employee Stock Purchase Plan.

F3 · balance_after: Reflects all transactions reported under this report.

SEC source: 0001209191-24-005923 · doc4.xml · derivative · entry 1

Chacko David M. · CIK 0001871801 · CFO and CBO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 278,812

Underlying: Common Stock · 278,812 shares

Expires 2034-06-19

F1 · derivative.exercise_date: 1/48th of the shares subject to the option vest monthly, with vesting starting on June 20, 2024, subject to the Reporting Person's continuous service to the Issuer on each such vesting date.

SEC source: 0001209191-24-005929 · doc4.xml · derivative · entry 1

Varney Michael David · CIK 0001638647 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,000

Underlying: Common Stock · 60,000 shares

Expires 2034-06-19

F1 · derivative.exercise_date: 100% of the options to purchase shares vest on June 20, 2025, subject to the Reporting Person's continuous service to the Issuer on such vesting date.