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Nasdaq · USD

ALNY

ALNYLAM PHARMACEUTICALS, INC.

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3132
SEC CIK
0001178670
Parsed reports
483

Last 12 months

Inside the activity.

0 purchase rows · 279 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025031
Dec 202500
Jan 20260111
Feb 2026011
Mar 20260106
Apr 2026014
May 202600
Jun 202605
Jul 202600
Aug 202600
Sep 202600
Oct 202601

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
SaleCommon Stock 20,172 $144.53 $2,915,459.16
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 8

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,595

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

F6 · price: Sale prices ranged from $144.01 to $145.00

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
SaleCommon Stock 19,213 $143.46 $2,756,296.98
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 7

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,767

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

F5 · price: Sale prices ranged from $143.01 to $143.98

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
SaleCommon Stock 21,336 $142.57 $3,041,873.52
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 6

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,980

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

F4 · price: Sale prices ranged from $142.01 to $143.00

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
SaleCommon Stock 15,000 $141.69 $2,125,350.00
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 5

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,316

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

F3 · price: Sale prices ranged from $141.01 to $142.00

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
SaleCommon Stock 6,453 $140.45 $906,323.85
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 4

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 93,316

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

F2 · price: Sale prices ranged from $140.00 to $140.95

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
Exercise / conversionCommon Stock 5,000 $7.10 $35,500.00
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 3

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,769

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
Exercise / conversionCommon Stock 38,913 $16.43 $639,340.59
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 2

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,769

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC
Vaishnaw AkshayPresident, R&D
Exercise / conversionCommon Stock 44,641 $18.66 $833,001.06
Disclosure

SEC source: 0001553878-18-000027 · edgardoc.xml · nonDerivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,856

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 10, 2018.

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC SaleCommon Stock 1,300 $145.41 $189,033.00
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 6

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,968

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F7 · price: Sale prices ranged from $145.16 to $145.79

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC SaleCommon Stock 9,165 $144.67 $1,325,900.55
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 5

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 63,268

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F6 · price: Sale prices ranged from $144.14 to $145.13

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC SaleCommon Stock 8,644 $143.58 $1,241,105.52
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,433

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F5 · price: Sale prices ranged from $143.12 to $144.11

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC SaleCommon Stock 9,217 $142.68 $1,315,081.56
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,077

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F4 · price: Sale prices ranged from $142.12 to $143.11

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC SaleCommon Stock 7,250 $141.74 $1,027,615.00
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,294

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F3 · price: Sale prices ranged from $141.12 to $142.10

Read SEC document
March 14, 2018 Filed Mar 16, 2018 21:05 UTC SaleCommon Stock 2,884 $140.43 $405,000.12
Disclosure

SEC source: 0001553878-18-000026 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 97,544

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on January 11, 2018.

F2 · price: Sale prices ranged from $140.00 to $140.95

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $77.40 $0.00
Disclosure

SEC source: 0001553878-18-000023 · edgardoc.xml · derivative · entry 7

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,000

Underlying: Common Stock · 10,000 shares

Expires 2024-09-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F3 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC
KEATING LAURIESVP, GC & Secretary
SaleCommon Stock 10,000 $150.00 $1,500,000.00
Disclosure

SEC source: 0001553878-18-000023 · edgardoc.xml · nonDerivative · entry 4

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,500

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionCommon Stock 10,000 $77.40 $774,000.00
Disclosure

SEC source: 0001553878-18-000023 · edgardoc.xml · nonDerivative · entry 3

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC Exercise / conversionStock Option (right to buy) · Derivative 2,117 $0.00 Strike: $63.86 $0.00
Disclosure

SEC source: 0001553878-18-000022 · edgardoc.xml · derivative · entry 6

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,117 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $59.25 $0.00
Disclosure

SEC source: 0001553878-18-000022 · edgardoc.xml · derivative · entry 5

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC SaleCommon Stock 17,117 $150.00 $2,567,550.00
Disclosure

SEC source: 0001553878-18-000022 · edgardoc.xml · nonDerivative · entry 3

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC Exercise / conversionCommon Stock 15,000 $59.25 $888,750.00
Disclosure

SEC source: 0001553878-18-000022 · edgardoc.xml · nonDerivative · entry 2

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,117

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:40 UTC Exercise / conversionCommon Stock 2,117 $63.86 $135,191.62
Disclosure

SEC source: 0001553878-18-000022 · edgardoc.xml · nonDerivative · entry 1

Ausiello Dennis A · CIK 0001381994 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,117

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 1, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $21.35 $0.00
Disclosure

SEC source: 0001553878-18-000021 · edgardoc.xml · derivative · entry 4

SHARP PHILIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2018-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 10, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC SaleCommon Stock 15,000 $149.00 $2,235,000.00
Disclosure

SEC source: 0001553878-18-000021 · edgardoc.xml · nonDerivative · entry 2

SHARP PHILIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,795

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 10, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionCommon Stock 15,000 $21.35 $320,250.00
Disclosure

SEC source: 0001553878-18-000021 · edgardoc.xml · nonDerivative · entry 1

SHARP PHILIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,795

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 10, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $30.09 $0.00
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · derivative · entry 8

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2023-06-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionStock Option (right to buy) · Derivative 2,823 $0.00 Strike: $63.86 $0.00
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · derivative · entry 7

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,823 shares

Expires 2024-01-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

F3 · derivative.exercise_date: The stock option vests as to 25% on 3/31/2014 and as to an additional 25% of the shares granted at the end of each subsequent quarter.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $59.25 $0.00
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · derivative · entry 6

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2024-06-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC SaleCommon Stock 27,823 $150.00 $4,173,450.00
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · nonDerivative · entry 4

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionCommon Stock 15,000 $59.25 $888,750.00
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · nonDerivative · entry 3

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,823

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionCommon Stock 2,823 $63.86 $180,276.78
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · nonDerivative · entry 2

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,823

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

Read SEC document
March 13, 2018 Filed Mar 14, 2018 23:39 UTC Exercise / conversionCommon Stock 10,000 $30.09 $300,900.00
Disclosure

SEC source: 0001553878-18-000020 · edgardoc.xml · nonDerivative · entry 1

SCHIMMEL PAUL · CIK 0001236447 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 23, 2017.

Read SEC document
March 12, 2018 Filed Mar 14, 2018 23:40 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $77.40 $0.00
Disclosure

SEC source: 0001553878-18-000023 · edgardoc.xml · derivative · entry 6

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 82,000

Underlying: Common Stock · 10,000 shares

Expires 2024-09-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

F3 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
March 12, 2018 Filed Mar 14, 2018 23:40 UTC
KEATING LAURIESVP, GC & Secretary
SaleCommon Stock 10,000 $140.00 $1,400,000.00
Disclosure

SEC source: 0001553878-18-000023 · edgardoc.xml · nonDerivative · entry 2

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,500

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

Read SEC document
March 12, 2018 Filed Mar 14, 2018 23:40 UTC
KEATING LAURIESVP, GC & Secretary
Exercise / conversionCommon Stock 10,000 $77.40 $774,000.00
Disclosure

SEC source: 0001553878-18-000023 · edgardoc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 22, 2017.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 21:22 UTC Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $27.28 $0.00
Disclosure

SEC source: 0001325812-18-000020 · edgardoc.xml · derivative · entry 4

SHARP PHILIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2018-06-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 10, 2017.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 21:22 UTC SaleCommon Stock 15,000 $129.00 $1,935,000.00
Disclosure

SEC source: 0001325812-18-000020 · edgardoc.xml · nonDerivative · entry 2

SHARP PHILIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,795

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 10, 2017.

Read SEC document
March 09, 2018 Filed Mar 13, 2018 21:22 UTC Exercise / conversionCommon Stock 15,000 $27.28 $409,200.00
Disclosure

SEC source: 0001325812-18-000020 · edgardoc.xml · nonDerivative · entry 1

SHARP PHILIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,795

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 10, 2017.

Read SEC document
March 01, 2018 Filed Mar 5, 2018 22:49 UTC GrantStock Option (right to buy) · Derivative 25,000 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000015 · edgardoc.xml · derivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 25,000 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

Read SEC document
March 01, 2018 Filed Mar 5, 2018 22:49 UTC
Mason MichaelVP, Finance and Treasurer
GrantStock Option (right to buy) · Derivative 4,000 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000013 · edgardoc.xml · derivative · entry 1

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,000

Underlying: Common Stock · 4,000 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 4,000 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

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March 01, 2018 Filed Mar 5, 2018 22:49 UTC
Soni Manmeet SinghChief Financial Officer
GrantStock Option (right to buy) · Derivative 8,938 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000014 · edgardoc.xml · derivative · entry 1

Soni Manmeet Singh · CIK 0001569769 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,938

Underlying: Common Stock · 8,938 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 8,937 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

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March 01, 2018 Filed Mar 5, 2018 22:48 UTC
KEATING LAURIESVP, GC & Secretary
GrantStock Option (right to buy) · Derivative 13,750 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000011 · edgardoc.xml · derivative · entry 1

KEATING LAURIE · CIK 0001620743 · SVP, GC & Secretary

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,750

Underlying: Common Stock · 13,750 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 13,750 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

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March 01, 2018 Filed Mar 5, 2018 22:49 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantStock Option (right to buy) · Derivative 52,500 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000012 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,500

Underlying: Common Stock · 52,500 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 52,500 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

Read SEC document
March 01, 2018 Filed Mar 5, 2018 22:48 UTC
Greenstreet YvonneEVP, Chief Operating Officer
GrantStock Option (right to buy) · Derivative 25,000 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000010 · edgardoc.xml · derivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · EVP, Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 25,000 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

Read SEC document
March 01, 2018 Filed Mar 5, 2018 22:48 UTC GrantStock Option (right to buy) · Derivative 30,000 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001553878-18-000009 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2028-02-28

F1 · shares: Represents the time-vested portion of the reporting person's Annual Stock Option Award for 2017. The reporting person also received 30,000 options to purchase shares of ALNY common stock that will vest upon the achievement of three specific performance conditions, which will be reported on a Form 4 if and when each performance condition is met and the option vests.

F2 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to the remaining shares ratably at the end of each three-month period thereafter over the following thirty-three (33) months

Read SEC document
January 17, 2018 Filed Aug 14, 2018 23:14 UTC OtherCommon Stock 17 $0.00 $0.00
Disclosure

SEC source: 0001325812-18-000031 · primary_doc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 2,827

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
January 17, 2018 Filed Aug 14, 2018 22:00 UTC
Mason MichaelVP, Finance and Treasurer
OtherCommon Stock 5 $0.00 $0.00
Disclosure

SEC source: 0001735276-18-000049 · edgardoc.xml · nonDerivative · entry 3

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 231

F2 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F2 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F2 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

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January 17, 2018 Filed Aug 14, 2018 21:54 UTC
Soni Manmeet SinghChief Financial Officer
OtherCommon Stock 6 $0.00 $0.00
Disclosure

SEC source: 0001735276-18-000048 · edgardoc.xml · nonDerivative · entry 3

Soni Manmeet Singh · CIK 0001569769 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 19

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionStock Option (right to buy) · Derivative 10,000 $0.00 Strike: $97.72 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 23

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2025-12-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

Read SEC document
January 04, 2018 Filed Jan 8, 2018 22:02 UTC
Mason MichaelVP, Finance and Treasurer
Exercise / conversionStock Option (right to buy) · Derivative 6,187 $0.00 Strike: $96.45 $0.00
Disclosure

SEC source: 0001325812-18-000004 · edgardoc.xml · derivative · entry 22

Mason Michael · CIK 0001514291 · VP, Finance and Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,063

Underlying: Common Stock · 6,187 shares

Expires 2024-12-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on October 2, 2017.

F9 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.