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ALNY

ALNYLAM PHARMACEUTICALS, INC.

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Tapewire entity
3132
SEC CIK
0001178670
Parsed reports
483

Last 12 months

Inside the activity.

0 purchase rows · 279 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025031
Dec 202500
Jan 20260111
Feb 2026011
Mar 20260106
Apr 2026014
May 202600
Jun 202605
Jul 202600
Aug 202600
Sep 202600
Oct 202601

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
January 27, 2020 Filed Jan 29, 2020 21:03 UTC
KEATING LAURIEEVP, Chief Legal Officer
Exercise / conversionCommon Stock 25,000 $42.22 $1,055,500.00
Disclosure

SEC source: 0001735276-20-000002 · edgardoc.xml · nonDerivative · entry 2

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,632

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 26, 2019.

Read SEC document
January 27, 2020 Filed Jan 29, 2020 21:03 UTC
KEATING LAURIEEVP, Chief Legal Officer
Exercise / conversionCommon Stock 9,374 $42.22 $395,770.28
Disclosure

SEC source: 0001735276-20-000002 · edgardoc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,632

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 26, 2019.

Read SEC document
January 27, 2020 Filed Feb 12, 2020 21:02 UTC Amendment
KEATING LAURIEEVP, Chief Legal Officer
Exercise / conversionCommon Stock 3,663 $77.40 $283,516.20
Disclosure

SEC source: 0001735276-20-000013 · edgardoc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,258

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The transaction reported on this Form 4 was made pursuant to Rule 10b5-1 trading plan adopted by the reporting person on November 26, 2019. Reflects shares acquired upon the exercise by the reporting person of a stock option on January 27, 2020. This acquisition was inadvertently omitted from the Form 4 filed on January 29, 2020 which reported both the exercise of the stock option and the subsequent sale of such acquired shares.

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January 03, 2020 Filed Feb 28, 2020 21:07 UTC
Poulton Jeffrey V.Chief Financial Officer
OtherCommon Stock 19 $0.00 $0.00
Disclosure

SEC source: 0001735276-20-000032 · edgardoc.xml · nonDerivative · entry 1

Poulton Jeffrey V. · CIK 0001782962 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 19

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Read SEC document
December 23, 2019 Filed Dec 26, 2019 21:04 UTC
Vaishnaw AkshayPresident, R&D
GrantPerformance Stock Option 2017 (right to buy) · Derivative 8,333 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000123 · edgardoc.xml · derivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,666

Underlying: Common Stock · 8,333 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the second performance criterion was met and the option vested as to the second one third of the shares as of December 23, 2019.

Read SEC document
December 23, 2019 Filed Dec 26, 2019 21:03 UTC
KEATING LAURIEEVP, Chief Legal Officer
GrantPerformance Stock Option 2017 (right to buy) · Derivative 4,583 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000121 · edgardoc.xml · derivative · entry 1

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,166

Underlying: Common Stock · 4,583 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the second performance criterion was met and the option vested as to the second one third of the shares as of December 23, 2019.

Read SEC document
December 23, 2019 Filed Dec 26, 2019 21:04 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantPerformance Stock Option 2017 (right to buy) · Derivative 17,498 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000122 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,996

Underlying: Common Stock · 17,498 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the second performance criterion was met and the option vested as to the second one third of the shares as of December 23, 2019.

Read SEC document
December 23, 2019 Filed Dec 26, 2019 21:02 UTC GrantPerformance Stock Option 2017 (right to buy) · Derivative 9,999 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000119 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,998

Underlying: Common Stock · 9,999 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the second performance criterion was met and the option vested as to the second one third of the shares as of December 23, 2019.

Read SEC document
December 23, 2019 Filed Dec 26, 2019 21:03 UTC
Greenstreet YvonneChief Operating Officer
GrantPerformance Stock Option 2017 (right to buy) · Derivative 8,333 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000120 · edgardoc.xml · derivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,666

Underlying: Common Stock · 8,333 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the second performance criterion was met and the option vested as to the second one third of the shares as of December 23, 2019.

Read SEC document
December 12, 2019 Filed Dec 13, 2019 21:25 UTC
Greenstreet YvonneChief Operating Officer
Tax withholdingCommon Stock 3,208 $120.61 $386,916.88
Disclosure

SEC source: 0001735276-19-000113 · edgardoc.xml · nonDerivative · entry 2

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,208

Read SEC document
December 12, 2019 Filed Dec 13, 2019 21:25 UTC
Greenstreet YvonneChief Operating Officer
GrantCommon Stock 7,500 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000113 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,416

F1 · kind: On June 29, 2017, the reporting person was granted a restricted stock unit (RSU) to purchase shares of ALNY common stock. One half of the shares subject to release vested upon the achievement of each of two specific commercial events as approved by the compensation committee of the company. The compensation committee determined that the second performance criterion was met and therefore the second and final half of the shares vested as of December 12, 2019.

Read SEC document
November 22, 2019 Filed Nov 26, 2019 21:08 UTC GrantPerformance Stock Option 2017 (right to buy) · Derivative 9,999 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000110 · edgardoc.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,999

Underlying: Common Stock · 9,999 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the first performance criterion was met on November 22, 2019 and the option vested as to the first one third of the shares as of such date.

Read SEC document
November 22, 2019 Filed Nov 26, 2019 21:07 UTC
KEATING LAURIEEVP, Chief Legal Officer
GrantPerformance Stock Option 2017 (right to buy) · Derivative 4,583 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000109 · edgardoc.xml · derivative · entry 3

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,583

Underlying: Common Stock · 4,583 shares

Expires 2028-03-01

F2 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the first performance criterion was met on November 22, 2019 and the option vested as to the first one third of the shares as of such date.

Read SEC document
November 22, 2019 Filed Nov 26, 2019 21:06 UTC
Greenstreet YvonneChief Operating Officer
GrantPerformance Stock Option 2017 (right to buy) · Derivative 8,333 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000108 · edgardoc.xml · derivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,333

Underlying: Common Stock · 8,333 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the first performance criterion was met on November 22, 2019 and the option vested as to the first one third of the shares as of such date.

Read SEC document
November 22, 2019 Filed Nov 26, 2019 21:05 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
GrantPerformance Stock Option 2017 (right to buy) · Derivative 17,498 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000107 · edgardoc.xml · derivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,498

Underlying: Common Stock · 17,498 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the first performance criterion was met on November 22, 2019 and the option vested as to the first one third of the shares as of such date.

Read SEC document
November 22, 2019 Filed Nov 26, 2019 21:05 UTC
Vaishnaw AkshayPresident, R&D
GrantPerformance Stock Option 2017 (right to buy) · Derivative 8,333 $0.00 Strike: $119.13 $0.00
Disclosure

SEC source: 0001735276-19-000106 · edgardoc.xml · derivative · entry 1

Vaishnaw Akshay · CIK 0001458494 · President, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,333

Underlying: Common Stock · 8,333 shares

Expires 2028-03-01

F1 · kind: On March 1, 2018, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One third of the shares subject to the option vest upon the achievement of each of three specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the first performance criterion was met on November 22, 2019 and the option vested as to the first one third of the shares as of such date.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:05 UTC
Greenstreet YvonneChief Operating Officer
Exercise / conversionStock Option (right to buy) · Derivative 2,154 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-19-000099 · edgardoc.xml · derivative · entry 6

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,625

Underlying: Common Stock · 2,154 shares

Expires 2026-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 20, 2018.

F3 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:05 UTC
Greenstreet YvonneChief Operating Officer
Exercise / conversionPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-19-000099 · edgardoc.xml · derivative · entry 5

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,750

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 20, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:05 UTC
Greenstreet YvonneChief Operating Officer
SaleCommon Stock 8,404 $105.00 $882,420.00
Disclosure

SEC source: 0001735276-19-000099 · edgardoc.xml · nonDerivative · entry 3

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,916

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 20, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:05 UTC
Greenstreet YvonneChief Operating Officer
Exercise / conversionCommon Stock 6,250 $42.22 $263,875.00
Disclosure

SEC source: 0001735276-19-000099 · edgardoc.xml · nonDerivative · entry 2

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,320

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 20, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:05 UTC
Greenstreet YvonneChief Operating Officer
Exercise / conversionCommon Stock 2,154 $42.22 $90,941.88
Disclosure

SEC source: 0001735276-19-000099 · edgardoc.xml · nonDerivative · entry 1

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,070

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 20, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $30.09 $0.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · derivative · entry 9

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2023-06-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionStock Option (right to buy) · Derivative 15,000 $0.00 Strike: $9.30 $0.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · derivative · entry 8

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2021-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 15,000 $0.00 Strike: $11.33 $0.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · derivative · entry 7

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2022-06-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 30,000 $0.00 Strike: $9.14 $0.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · derivative · entry 6

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 30,000 shares

Expires 2020-12-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

F2 · derivative.exercise_date: The stock option will vest as to one third of the shares on each of the first, second and third anniversaries of the date of grant.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC SaleCommon Stock 75,000 $100.00 $7,500,000.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · nonDerivative · entry 5

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionCommon Stock 15,000 $30.09 $451,350.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · nonDerivative · entry 4

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 75,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionCommon Stock 15,000 $11.33 $169,950.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · nonDerivative · entry 3

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionCommon Stock 15,000 $9.30 $139,500.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · nonDerivative · entry 2

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 20, 2019 Filed Nov 22, 2019 21:06 UTC Exercise / conversionCommon Stock 30,000 $9.14 $274,200.00
Disclosure

SEC source: 0001735276-19-000100 · edgardoc.xml · nonDerivative · entry 1

Fanucci Marsha · CIK 0001298814 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 16, 2018.

Read SEC document
November 18, 2019 Filed Nov 20, 2019 21:17 UTC Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative 15,000 $0.00 Strike: $16.43 $0.00
Disclosure

SEC source: 0001735276-19-000096 · edgardoc.xml · derivative · entry 6

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 15,000 shares

Expires 2019-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 13, 2019. The 15,000 options exercised and sold by the reporting person were due to expire on December 9, 2019.

Read SEC document
November 18, 2019 Filed Nov 20, 2019 21:17 UTC SaleCommon Stock 810 $92.66 $75,054.60
Disclosure

SEC source: 0001735276-19-000096 · edgardoc.xml · nonDerivative · entry 4

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 235,633

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 13, 2019. The 15,000 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F4 · price: Sale prices ranged from $92.53 to $92.74.

Read SEC document
November 18, 2019 Filed Nov 20, 2019 21:17 UTC SaleCommon Stock 8,631 $91.97 $793,793.07
Disclosure

SEC source: 0001735276-19-000096 · edgardoc.xml · nonDerivative · entry 3

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 236,443

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 13, 2019. The 15,000 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F3 · price: Sale prices ranged from $91.50 to $92.48.

Read SEC document
November 18, 2019 Filed Nov 20, 2019 21:17 UTC SaleCommon Stock 5,559 $91.17 $506,814.03
Disclosure

SEC source: 0001735276-19-000096 · edgardoc.xml · nonDerivative · entry 2

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 245,074

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 13, 2019. The 15,000 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F2 · price: Sale prices ranged from $90.50 to $91.49.

Read SEC document
November 18, 2019 Filed Nov 20, 2019 21:17 UTC Exercise / conversionCommon Stock 15,000 $16.43 $246,450.00
Disclosure

SEC source: 0001735276-19-000096 · edgardoc.xml · nonDerivative · entry 1

SHARP PHILLIP A · CIK 0001226295 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 250,633

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 13, 2019. The 15,000 options exercised and sold by the reporting person were due to expire on December 9, 2019.

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October 23, 2019 Filed Oct 24, 2019 20:04 UTC OtherCommon Stock 5,544 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 4

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Indirect · by Trust

Disclosed balance after: 3,486

F2 · kind: These shares were distributed in October 2019 to the reporting person from the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT).

F3 · ownership.nature: Represents remaining shares held by the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT), of which Barry E. Greene is the sole Trustee

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October 23, 2019 Filed Oct 24, 2019 20:04 UTC OtherCommon Stock 5,544 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 3

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 58,482

F2 · kind: These shares were distributed in October 2019 to the reporting person from the "Barry E. Greene Qualified Annuity Interest Trust" (GRAT).

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October 22, 2019 Filed Oct 24, 2019 20:04 UTC Exercise / conversionStock Option (right to buy) · Derivative 58,913 $0.00 Strike: $16.43 $0.00
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · derivative · entry 6

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 58,913 shares

Expires 2019-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 14, 2019. The 58,913 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F5 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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October 22, 2019 Filed Oct 24, 2019 20:04 UTC SaleCommon Stock 58,913 $89.99 $5,301,580.87
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 2

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,938

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 14, 2019. The 58,913 options exercised and sold by the reporting person were due to expire on December 9, 2019.

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October 22, 2019 Filed Oct 24, 2019 20:04 UTC Exercise / conversionCommon Stock 58,913 $16.43 $967,940.59
Disclosure

SEC source: 0001735276-19-000094 · edgardoc.xml · nonDerivative · entry 1

Greene Barry E · CIK 0001291963 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 111,851

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 14, 2019. The 58,913 options exercised and sold by the reporting person were due to expire on December 9, 2019.

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October 14, 2019 Filed Oct 16, 2019 20:06 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionStock Option (right to buy) · Derivative 49,456 $0.00 Strike: $16.43 $0.00
Disclosure

SEC source: 0001735276-19-000092 · edgardoc.xml · derivative · entry 6

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 49,456 shares

Expires 2019-12-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 11, 2019. The 49,456 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F6 · derivative.exercise_date: The stock option vests as to 25% of the shares on the 1st anniversary of the date of the stock option grant and as to an additional 6.25% of the shares each successive three month period thereafter.

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October 14, 2019 Filed Oct 16, 2019 20:06 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 1,870 $80.31 $150,179.70
Disclosure

SEC source: 0001735276-19-000092 · edgardoc.xml · nonDerivative · entry 4

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 189,993

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 11, 2019. The 49,456 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F4 · price: Sale prices ranged from $80.28 to $80.44

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October 14, 2019 Filed Oct 16, 2019 20:06 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 26,754 $79.80 $2,134,969.20
Disclosure

SEC source: 0001735276-19-000092 · edgardoc.xml · nonDerivative · entry 3

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 191,863

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 11, 2019. The 49,456 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F3 · price: Sale prices ranged from $79.27 to $80.26

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October 14, 2019 Filed Oct 16, 2019 20:06 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
SaleCommon Stock 20,832 $78.92 $1,644,061.44
Disclosure

SEC source: 0001735276-19-000092 · edgardoc.xml · nonDerivative · entry 2

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 218,617

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 11, 2019. The 49,456 options exercised and sold by the reporting person were due to expire on December 9, 2019.

F2 · price: Sale prices ranged from $78.27 to $79.26

Read SEC document
October 14, 2019 Filed Oct 16, 2019 20:06 UTC
MARAGANORE JOHNDirector · Chief Executive Officer
Exercise / conversionCommon Stock 49,456 $16.43 $812,562.08
Disclosure

SEC source: 0001735276-19-000092 · edgardoc.xml · nonDerivative · entry 1

MARAGANORE JOHN · CIK 0001180432 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 239,449

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: All sales reported on this Form 4 were made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 11, 2019. The 49,456 options exercised and sold by the reporting person were due to expire on December 9, 2019.

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October 10, 2019 Filed Nov 26, 2019 21:07 UTC
KEATING LAURIEEVP, Chief Legal Officer
OtherCommon Stock 10 $0.00 $0.00
Disclosure

SEC source: 0001735276-19-000109 · edgardoc.xml · nonDerivative · entry 1

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 434

F1 · kind: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F1 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

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October 10, 2019 Filed Apr 21, 2021 22:22 UTC
Poulton Jeffrey V.Chief Financial Officer
OtherCommon Stock 38 $0.00 $0.00
Disclosure

SEC source: 0001735276-21-000040 · edgardoc.xml · nonDerivative · entry 4

Poulton Jeffrey V. · CIK 0001782962 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · by Managed Account

Disclosed balance after: 38

F3 · kind: Reflects shares of ALNY common stock acquired by the reporting person on October 10, 2019 under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program. This acquisition and indirect holding was inadvertently omitted from previously filed Form 4 reports.

F4 · price: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

F4 · ownership.nature: Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

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August 06, 2019 Filed Aug 7, 2019 20:17 UTC
Greenstreet YvonneChief Operating Officer
GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-19-000087 · edgardoc.xml · derivative · entry 3

Greenstreet Yvonne · CIK 0001446125 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F2 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option vested upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the fourth performance criterion was met effective as of August 6, 2019 and the option vested as to the final one-quarter of the shares as of such date.

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August 06, 2019 Filed Aug 7, 2019 20:17 UTC
KEATING LAURIEEVP, Chief Legal Officer
GrantPerformance Stock Option 2016 (right to buy) · Derivative 6,250 $0.00 Strike: $42.22 $0.00
Disclosure

SEC source: 0001735276-19-000086 · edgardoc.xml · derivative · entry 4

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 6,250 shares

Expires 2026-12-20

F3 · kind: On December 20, 2016, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option vested upon the achievement of each of four specific clinical development, regulatory or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the fourth performance criterion was met effective as of August 6, 2019 and the option vested as to the final one-quarter of the shares as of such date.

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August 06, 2019 Filed Aug 7, 2019 20:17 UTC
KEATING LAURIEEVP, Chief Legal Officer
GrantPerformance Stock Option 2015 (right to buy) · Derivative 3,500 $0.00 Strike: $88.95 $0.00
Disclosure

SEC source: 0001735276-19-000086 · edgardoc.xml · derivative · entry 3

KEATING LAURIE · CIK 0001620743 · EVP, Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,000

Underlying: Common Stock · 3,500 shares

Expires 2025-12-18

F2 · kind: On December 18, 2015, the reporting person was granted a performance based stock option to purchase shares of ALNY common stock. One quarter of the shares subject to the option vested upon the achievement of each of four specific clinical development or commercial events, as approved by our compensation committee. The compensation committee of the Company determined that the fourth performance criterion was met effective as of August 6, 2019 and the option vested as to the final one-quarter of the shares as of such date.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.