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Flagship Pioneering Fund VII General Partner LLC

Disclosed activity across 6 companies

Tapewire entity
63981
SEC CIK
0001805917

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Evelo Biosciences, Inc.EVLO · Entity 10846810% ownerJuly 11, 2023July 13, 2023
Foghorn Therapeutics Inc.FHTX · Entity 5820Director · 10% ownerJanuary 13, 2026January 15, 2026
Generate Biomedicines, Inc.GENB · Entity 155310% ownerFebruary 26, 2026March 02, 2026
Omega Therapeutics, Inc.OMGA · Entity 8361810% ownerFebruary 27, 2023February 27, 2023
Sana Biotechnology, Inc.SANA · Entity 487010% ownerFebruary 12, 2024February 14, 2024
Seres Therapeutics, Inc.MCRB · Entity 719110% ownerJuly 05, 2022July 07, 2022

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectBy Flagship Ventures Fund IV, L.P.1,461,795 Reported balance After 2023-07-11 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 1 · 2023-07-11 · Purchase · Acquired 1,082,251 · Balance 1,461,795

F1: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F2: Shares held by Flagship Fund IV. Flagship Ventures Fund IV General Partner LLC ("Flagship Fund IV GP") is the general partner of Flagship Fund IV. Noubar B. Afeyan, Ph.D. ("Dr. Afeyan") is the sole manager of Flagship Fund IV GP. Each of the reporting persons except for Flagship Fund IV disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Nutritional Health LTP Fund, L.P.1,493,241 Reported balance After 2023-07-11 transaction · row 2 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 2 · 2023-07-11 · Purchase · Acquired 1,082,251 · Balance 1,493,241

F1: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F3: Shares held by Nutritional LTP. Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Nutritional LTP GP. Dr. Afeyan is the Chief Executive Officer, director and sole stockholder of Flagship Pioneering. Each of the reporting persons except for Nutritional LTP disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship Pioneering Fund VII, L.P.3,931,685 Reported balance After 2023-07-11 transaction · row 3 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 3 · 2023-07-11 · Purchase · Acquired 3,246,753 · Balance 3,931,685

F1: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F4: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the reporting persons except for Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship Ventures Fund IV-Rx, L.P.94,371 Reported balance Holding disclosure · report date 2023-07-11 · row 4 Holding and transaction disclosures are not merged.
1 source row

Row 4 · Balance 94,371

F5: Shares held by Flagship Ventures Fund IV-Rx, L.P ("Flagship Fund IV-Rx"). Flagship Fund IV GP is the general partner of Flagship Fund IV-Rx. Each of the reporting persons except for Flagship Fund IV-Rx disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship Ventures Opportunities Fund I, L.P.274,766 Reported balance Holding disclosure · report date 2023-07-11 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 274,766

F6: Shares held by Flagship Ventures Opportunities Fund I, L.P. ("Flagship Opportunities I"). Flagship Ventures Opportunities Fund I General Partner LLC ("Flagship Opportunities GP") is the general partner of Flagship Opportunities I. Dr. Afeyan is the sole manager of Flagship Opportunities GP. Each of the reporting persons except for Flagship Opportunities I disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship VentureLabs IV LLC34,219 Reported balance Holding disclosure · report date 2023-07-11 · row 6 Holding and transaction disclosures are not merged.
1 source row

Row 6 · Balance 34,219

F7: Shares held by Flagship VentureLabs IV, LLC ("VentureLabs IV"). Flagship Fund IV is the manager of VentureLabs IV. Each of the reporting persons except for VentureLabs IV disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship VentureLabs V LLC132,282 Reported balance Holding disclosure · report date 2023-07-11 · row 7 Holding and transaction disclosures are not merged.
1 source row

Row 7 · Balance 132,282

F8: Shares held by Flagship VentureLabs V LLC ("VentureLabs V"). Flagship VentureLabs V Manager LLC ("VentureLabs V Manager") serves as manager of VentureLabs V. Flagship Pioneering is the manager of VentureLabs V Manager. Each of the reporting persons except for VentureLabs V disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship Ventures Fund V, L.P.210,064 Reported balance Holding disclosure · report date 2023-07-11 · row 8 Holding and transaction disclosures are not merged.
1 source row

Row 8 · Balance 210,064

F9: Shares held by Flagship Ventures Fund V, L.P. ("Flagship Fund V"). Flagship Ventures Fund V General Partner LLC ("Flagship Fund V GP") is the general partner of Flagship Fund V. Dr. Afeyan serves as sole manager of Flagship Fund V. Each of the reporting persons except for Flagship Fund V disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Flagship V VentureLabs Rx Fund, L.P.80,494 Reported balance Holding disclosure · report date 2023-07-11 · row 9 Holding and transaction disclosures are not merged.
1 source row

Row 9 · Balance 80,494

F10: Shares held by Flagship V VentureLabs Rx Fund, L.P. ("VentureLabs Rx V"). Flagship Fund V GP is the general partner of VentureLabs Rx V. Each of the reporting persons except for VentureLabs Rx V disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Nutritional Health Side Fund, L.P.39,798 Reported balance Holding disclosure · report date 2023-07-11 · row 10 Holding and transaction disclosures are not merged.
1 source row

Row 10 · Balance 39,798

F11: Shares held by Nutritional Health Side Fund, L.P. ("Nutritional Health Side Fund"). Flagship Fund V GP is the general partner of Nutritional Health Side Fund. Each of the reporting persons except for Nutritional Health Side Fund disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Common StockSEC Table I · non-derivativeIndirectBy Nutritional Health Disruptive Innovation Fund, L.P.179,909 Reported balance Holding disclosure · report date 2023-07-11 · row 11 Holding and transaction disclosures are not merged.
1 source row

Row 11 · Balance 179,909

F12: Shares held by Nutritional Health Disruptive Innovation Fund, L.P. ("Nutritional Innovation Fund"). Flagship Fund V GP is the general partner of Nutritional Innovation Fund. Each of the reporting persons except for Nutritional Innovation Fund disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F2: Shares held by Flagship Fund IV. Flagship Ventures Fund IV General Partner LLC ("Flagship Fund IV GP") is the general partner of Flagship Fund IV. Noubar B. Afeyan, Ph.D. ("Dr. Afeyan") is the sole manager of Flagship Fund IV GP. Each of the reporting persons except for Flagship Fund IV disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F3: Shares held by Nutritional LTP. Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Nutritional LTP GP. Dr. Afeyan is the Chief Executive Officer, director and sole stockholder of Flagship Pioneering. Each of the reporting persons except for Nutritional LTP disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F4: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the reporting persons except for Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F5: Shares held by Flagship Ventures Fund IV-Rx, L.P ("Flagship Fund IV-Rx"). Flagship Fund IV GP is the general partner of Flagship Fund IV-Rx. Each of the reporting persons except for Flagship Fund IV-Rx disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F6: Shares held by Flagship Ventures Opportunities Fund I, L.P. ("Flagship Opportunities I"). Flagship Ventures Opportunities Fund I General Partner LLC ("Flagship Opportunities GP") is the general partner of Flagship Opportunities I. Dr. Afeyan is the sole manager of Flagship Opportunities GP. Each of the reporting persons except for Flagship Opportunities I disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F7: Shares held by Flagship VentureLabs IV, LLC ("VentureLabs IV"). Flagship Fund IV is the manager of VentureLabs IV. Each of the reporting persons except for VentureLabs IV disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F8: Shares held by Flagship VentureLabs V LLC ("VentureLabs V"). Flagship VentureLabs V Manager LLC ("VentureLabs V Manager") serves as manager of VentureLabs V. Flagship Pioneering is the manager of VentureLabs V Manager. Each of the reporting persons except for VentureLabs V disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F9: Shares held by Flagship Ventures Fund V, L.P. ("Flagship Fund V"). Flagship Ventures Fund V General Partner LLC ("Flagship Fund V GP") is the general partner of Flagship Fund V. Dr. Afeyan serves as sole manager of Flagship Fund V. Each of the reporting persons except for Flagship Fund V disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F10: Shares held by Flagship V VentureLabs Rx Fund, L.P. ("VentureLabs Rx V"). Flagship Fund V GP is the general partner of VentureLabs Rx V. Each of the reporting persons except for VentureLabs Rx V disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F11: Shares held by Nutritional Health Side Fund, L.P. ("Nutritional Health Side Fund"). Flagship Fund V GP is the general partner of Nutritional Health Side Fund. Each of the reporting persons except for Nutritional Health Side Fund disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

F12: Shares held by Nutritional Health Disruptive Innovation Fund, L.P. ("Nutritional Innovation Fund"). Flagship Fund V GP is the general partner of Nutritional Innovation Fund. Each of the reporting persons except for Nutritional Innovation Fund disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Pre-Funded Warrants to purchase Common StockSEC Table II · derivative / convertible security · Conversion / exercise price $0.00 · Expires 2046-01-13IndirectBy Flagship Pioneering Fund VII, L.P.2,235,468 Reported balance After 2026-01-13 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2026-01-13 · Grant · Acquired 2,235,468 · Balance 2,235,468

F1: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series 1 Warrants to purchase Common StockSEC Table II · derivative / convertible security · Conversion / exercise price $13.42 · Expires 2027-06-30IndirectBy Flagship Pioneering Fund VII, L.P.1,117,734 Reported balance After 2026-01-13 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-01-13 · Grant · Acquired 1,117,734 · Balance 1,117,734

F3: The Series Warrants are exercisable at an initial price of $13.42 per Series 1 Warrant and $20.13 per Series 2 Warrant. Subject to certain exclusions, if prior to June 30, 2027, the Company issues capital stock or securities convertible into or exercisable for capital stock in one or more related transactions primarily for capital raising at a weighted-average common stock equivalent price (the "Weighted-Average Price") below $13.42 per share, the exercise price of a Series Warrant shall reset upon exercise to the midpoint between the initial price and the lowest such Weighted-Average Price, but not below $6.71 per share. The exercise price may be adjusted only once pursuant to this mechanism.

F1: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series 2 Warrants to purchase Common StockSEC Table II · derivative / convertible security · Conversion / exercise price $20.13 · Expires 2030-12-31IndirectBy Flagship Pioneering Fund VII, L.P.1,117,734 Reported balance After 2026-01-13 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2026-01-13 · Grant · Acquired 1,117,734 · Balance 1,117,734

F3: The Series Warrants are exercisable at an initial price of $13.42 per Series 1 Warrant and $20.13 per Series 2 Warrant. Subject to certain exclusions, if prior to June 30, 2027, the Company issues capital stock or securities convertible into or exercisable for capital stock in one or more related transactions primarily for capital raising at a weighted-average common stock equivalent price (the "Weighted-Average Price") below $13.42 per share, the exercise price of a Series Warrant shall reset upon exercise to the midpoint between the initial price and the lowest such Weighted-Average Price, but not below $6.71 per share. The exercise price may be adjusted only once pursuant to this mechanism.

F1: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Filing footnotes · ownership attribution and instrument terms

F1: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3: The Series Warrants are exercisable at an initial price of $13.42 per Series 1 Warrant and $20.13 per Series 2 Warrant. Subject to certain exclusions, if prior to June 30, 2027, the Company issues capital stock or securities convertible into or exercisable for capital stock in one or more related transactions primarily for capital raising at a weighted-average common stock equivalent price (the "Weighted-Average Price") below $13.42 per share, the exercise price of a Series Warrant shall reset upon exercise to the midpoint between the initial price and the lowest such Weighted-Average Price, but not below $6.71 per share. The exercise price may be adjusted only once pursuant to this mechanism.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectBy Flagship Pioneering Fund VI, L.P.12,723,940 Reported balance After 2026-03-02 transaction · row 1 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 1 · 2026-03-02 · Conversion · Acquired 12,723,940 · Balance 12,723,940

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Common StockSEC Table I · non-derivativeIndirectBy Flagship Pioneering Fund VII, L.P.15,264,724 Last balance in matching sequence After 2026-03-02 transaction · row 6 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rows

Row 2 · 2026-03-02 · Conversion · Acquired 13,702,224 · Balance 13,702,224

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Row 6 · 2026-03-02 · Purchase · Acquired 1,562,500 · Balance 15,264,724

F3: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Common StockSEC Table I · non-derivativeIndirectBy Nutritional Health LTP Fund, L.P.987,491 Reported balance After 2026-03-02 transaction · row 3 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 3 · 2026-03-02 · Conversion · Acquired 987,491 · Balance 987,491

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Common StockSEC Table I · non-derivativeIndirectBy Flagship Pioneering Special Opportunities Fund II, L.P.2,777,752 Reported balance After 2026-03-02 transaction · row 4 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 4 · 2026-03-02 · Conversion · Acquired 2,777,752 · Balance 2,777,752

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Common StockSEC Table I · non-derivativeIndirectBy FPN II, L.P.4,340,252 Last balance in matching sequence After 2026-03-02 transaction · row 7 Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rows

Row 5 · 2026-03-02 · Conversion · Acquired 2,777,752 · Balance 2,777,752

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Row 7 · 2026-03-02 · Purchase · Acquired 1,562,500 · Balance 4,340,252

F6: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Common StockSEC Table I · non-derivativeIndirectBy Pioneering Medicines 02, LLC1,562,500 Reported balance After 2026-03-02 transaction · row 8 Joint disclosure: continuity of the reported position is unresolved; see ownership footnotes.
1 source row

Row 8 · 2026-03-02 · Purchase · Acquired 1,562,500 · Balance 1,562,500

F7: Securities held by Pioneering Medicine 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, is the sole manager of PM02, and Flagship Fund VII is its majority equity holder. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $16.00 · Expires 2036-02-25Direct29,561 Reported balance After 2026-02-26 transaction · row 10 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 10 · 2026-02-26 · Grant · Acquired 29,561 · Balance 29,561

F9: The shares underlying this option shall vest in full on February 19, 2027, subject to the Reporting Person's continued service on such vesting date.

Series A Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Fund VI, L.P.0 Reported balance After 2026-03-02 transaction · row 11 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 11 · 2026-03-02 · Conversion · Disposed 18,483,785 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Series A Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Fund VII, L.P.0 Reported balance After 2026-03-02 transaction · row 12 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 12 · 2026-03-02 · Conversion · Disposed 17,016,215 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series A Preferred StockSEC Table II · derivative / convertible securityIndirectBy Nutritional Health LTP Fund, L.P.0 Reported balance After 2026-03-02 transaction · row 13 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 13 · 2026-03-02 · Conversion · Disposed 1,500,000 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series B Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Fund VI, L.P.0 Reported balance After 2026-03-02 transaction · row 14 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 14 · 2026-03-02 · Conversion · Disposed 843,881 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Series B Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Fund VII, L.P.0 Reported balance After 2026-03-02 transaction · row 15 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 15 · 2026-03-02 · Conversion · Disposed 1,265,822 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series B Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Special Opportunities Fund II, L.P.0 Reported balance After 2026-03-02 transaction · row 16 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 16 · 2026-03-02 · Conversion · Disposed 2,953,586 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series B Preferred StockSEC Table II · derivative / convertible securityIndirectBy FPN II, L.P.0 Reported balance After 2026-03-02 transaction · row 17 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 17 · 2026-03-02 · Conversion · Disposed 2,109,704 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series C Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Fund VII, L.P.0 Reported balance After 2026-03-02 transaction · row 18 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 18 · 2026-03-02 · Conversion · Disposed 2,531,644 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series C Preferred StockSEC Table II · derivative / convertible securityIndirectBy Flagship Pioneering Special Opportunities Fund II, L.P.0 Reported balance After 2026-03-02 transaction · row 19 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 19 · 2026-03-02 · Conversion · Disposed 1,265,822 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Series C Preferred StockSEC Table II · derivative / convertible securityIndirectBy FPN II, L.P.0 Reported balance After 2026-03-02 transaction · row 20 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 20 · 2026-03-02 · Conversion · Disposed 2,109,704 · Balance 0

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Common StockSEC Table I · non-derivativeIndirectBy Flagship VentureLabs VI, LLC25,016,458 Reported balance Holding disclosure · report date 2026-02-26 · row 9 Holding and transaction disclosures are not merged.
1 source row

Row 9 · Balance 25,016,458

F8: Securities held by Flagship VentureLabs VI LLC ("VentureLabs VI"). Flagship VentureLabs VI Manager LLC ("VentureLabs VI Manager") is the manager of VentureLabs VI. Flagship Pioneering is the manager of VentureLabs VI Manager. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Filing footnotes · ownership attribution and instrument terms

F1: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

F3: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F7: Securities held by Pioneering Medicine 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, is the sole manager of PM02, and Flagship Fund VII is its majority equity holder. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F8: Securities held by Flagship VentureLabs VI LLC ("VentureLabs VI"). Flagship VentureLabs VI Manager LLC ("VentureLabs VI Manager") is the manager of VentureLabs VI. Flagship Pioneering is the manager of VentureLabs VI Manager. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F9: The shares underlying this option shall vest in full on February 19, 2027, subject to the Reporting Person's continued service on such vesting date.

Omega Therapeutics, Inc.

Report date February 27, 2023 · Filed February 27, 2023

Jointly reported with Flagship Pioneering Fund VII, L.P.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectBy Flagship Pioneering Fund VII, L.P.1,329,324 Reported balance Holding disclosure · report date 2023-02-27 · row 1 Holding and transaction disclosures are not merged.
1 source row

Row 1 · Balance 1,329,324

F1: On February 27, 2023, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") purchased 1,329,324 shares of the Issuer's Common Stock in a registered direct offering at a price of $5.78 per share pursuant to a Securities Purchase Agreement dated February 22, 2023.

F2: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the Chief Executive Officer, sole shareholder and director of Flagship Pioneering. Each of the reporting persons except Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Filing footnotes · ownership attribution and instrument terms

F1: On February 27, 2023, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") purchased 1,329,324 shares of the Issuer's Common Stock in a registered direct offering at a price of $5.78 per share pursuant to a Securities Purchase Agreement dated February 22, 2023.

F2: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the Chief Executive Officer, sole shareholder and director of Flagship Pioneering. Each of the reporting persons except Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Sana Biotechnology, Inc.

Report date February 12, 2024 · Filed February 14, 2024

Jointly reported with Flagship Pioneering Fund VII, L.P.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Pre-Funded Warrants to purchase Common StockSEC Table II · derivative / convertible security · Conversion / exercise price $0.00IndirectBy Flagship Pioneering Fund VII, L.P.Not disclosed Reported balance Holding disclosure · report date 2024-02-12 · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · Balance Not disclosed

F1: On February 12, 2024, pursuant to an underwritten public offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired pre-funded warrants to purchase 2,727,272 shares of Common Stock (the "Pre-Funded Warrants") at a purchase price of $5.4999 per Pre-Funded Warrant. The Pre-Funded Warrants do not have an expiration date.

F2: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the Chief Executive Officer, sole shareholder and director of Flagship Pioneering. Each of the reporting persons except Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Filing footnotes · ownership attribution and instrument terms

F1: On February 12, 2024, pursuant to an underwritten public offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired pre-funded warrants to purchase 2,727,272 shares of Common Stock (the "Pre-Funded Warrants") at a purchase price of $5.4999 per Pre-Funded Warrant. The Pre-Funded Warrants do not have an expiration date.

F2: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the Chief Executive Officer, sole shareholder and director of Flagship Pioneering. Each of the reporting persons except Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Seres Therapeutics, Inc.

Report date July 05, 2022 · Filed July 07, 2022

Jointly reported with Flagship Pioneering Fund VII, L.P.

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectBy Flagship Pioneering Fund VII, L.P.5,825,495 Reported balance Holding disclosure · report date 2022-07-05 · row 1 Holding and transaction disclosures are not merged.
1 source row

Row 1 · Balance 5,825,495

F1: On July 5, 2022, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 5,825,495 shares of the Issuer's Common Stock in a registered direct offering at a price of $3.15 per share.

F2: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Flagship Fund VII GP. Dr. Afeyan is the Chief Executive Officer, sole shareholder and director of Flagship Pioneering. Each of the reporting persons except Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Filing footnotes · ownership attribution and instrument terms

F1: On July 5, 2022, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 5,825,495 shares of the Issuer's Common Stock in a registered direct offering at a price of $3.15 per share.

F2: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Flagship Fund VII GP. Dr. Afeyan is the Chief Executive Officer, sole shareholder and director of Flagship Pioneering. Each of the reporting persons except Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries C Preferred Stock · Derivative 2,109,704 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 20

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,388,876 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries C Preferred Stock · Derivative 1,265,822 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 19

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 833,325 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries C Preferred Stock · Derivative 2,531,644 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 18

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,666,651 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries B Preferred Stock · Derivative 2,109,704 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 17

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,388,876 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries B Preferred Stock · Derivative 2,953,586 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 16

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,944,427 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries B Preferred Stock · Derivative 1,265,822 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 15

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 833,325 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries B Preferred Stock · Derivative 843,881 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 14

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 555,550 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries A Preferred Stock · Derivative 1,500,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 13

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 987,491 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4 · ownership.nature: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries A Preferred Stock · Derivative 17,016,215 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 12

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 11,202,248 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionSeries A Preferred Stock · Derivative 18,483,785 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 11

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 12,168,390 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 8

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Pioneering Medicines 02, LLC

Disclosed balance after: 1,562,500

F7 · ownership.nature: Securities held by Pioneering Medicine 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, is the sole manager of PM02, and Flagship Fund VII is its majority equity holder. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 7

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 4,340,252

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 6

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 15,264,724

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionCommon Stock 2,777,752 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 5

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 2,777,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

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March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionCommon Stock 2,777,752 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 4

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 2,777,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

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March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionCommon Stock 987,491 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 3

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 987,491

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4 · ownership.nature: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionCommon Stock 13,702,224 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 2

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 13,702,224

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 ConversionCommon Stock 12,723,940 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 1

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 12,723,940

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

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February 26, 2026 Filed Mar 2, 2026 17:52 UTC Generate Biomedicines, Inc. GENB · Entity 1553 GrantStock Option (Right to Buy) · Derivative 29,561 $0.00 Strike: $16.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 10

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,561

Underlying: Common Stock · 29,561 shares

Expires 2036-02-25

F9 · derivative.exercise_date: The shares underlying this option shall vest in full on February 19, 2027, subject to the Reporting Person's continued service on such vesting date.

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January 13, 2026 Filed Jan 15, 2026 17:00 UTC Foghorn Therapeutics Inc. FHTX · Entity 5820 GrantSeries 2 Warrants to purchase Common Stock · Derivative 1,117,734 Not disclosed Strike: $20.13 Not disclosed
Disclosure

SEC source: 0001193125-26-014218 · ownership.xml · derivative · entry 3

Flagship Pioneering, LLC · CIK 0001400240 · Director · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · Director · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · Director · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · Director · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · Director · 10% owner

Flagship Ventures Fund V General Partner LLC · CIK 0001724575 · Director · 10% owner

Flagship Ventures Fund V, L.P. · CIK 0001627639 · Director · 10% owner

Flagship Ventures Opportunities Fund I General Partner LLC · CIK 0001725004 · Director · 10% owner

Flagship Ventures Opportunities Fund I, L.P. · CIK 0001677345 · Director · 10% owner

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 1,117,734

Underlying: Common Stock · 1,117,734 shares

Expires 2030-12-31

F3 · derivative.exercise_price: The Series Warrants are exercisable at an initial price of $13.42 per Series 1 Warrant and $20.13 per Series 2 Warrant. Subject to certain exclusions, if prior to June 30, 2027, the Company issues capital stock or securities convertible into or exercisable for capital stock in one or more related transactions primarily for capital raising at a weighted-average common stock equivalent price (the "Weighted-Average Price") below $13.42 per share, the exercise price of a Series Warrant shall reset upon exercise to the midpoint between the initial price and the lowest such Weighted-Average Price, but not below $6.71 per share. The exercise price may be adjusted only once pursuant to this mechanism.

F1 · price: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2 · ownership.nature: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
January 13, 2026 Filed Jan 15, 2026 17:00 UTC Foghorn Therapeutics Inc. FHTX · Entity 5820 GrantSeries 1 Warrants to purchase Common Stock · Derivative 1,117,734 Not disclosed Strike: $13.42 Not disclosed
Disclosure

SEC source: 0001193125-26-014218 · ownership.xml · derivative · entry 2

Flagship Pioneering, LLC · CIK 0001400240 · Director · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · Director · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · Director · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · Director · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · Director · 10% owner

Flagship Ventures Fund V General Partner LLC · CIK 0001724575 · Director · 10% owner

Flagship Ventures Fund V, L.P. · CIK 0001627639 · Director · 10% owner

Flagship Ventures Opportunities Fund I General Partner LLC · CIK 0001725004 · Director · 10% owner

Flagship Ventures Opportunities Fund I, L.P. · CIK 0001677345 · Director · 10% owner

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 1,117,734

Underlying: Common Stock · 1,117,734 shares

Expires 2027-06-30

F3 · derivative.exercise_price: The Series Warrants are exercisable at an initial price of $13.42 per Series 1 Warrant and $20.13 per Series 2 Warrant. Subject to certain exclusions, if prior to June 30, 2027, the Company issues capital stock or securities convertible into or exercisable for capital stock in one or more related transactions primarily for capital raising at a weighted-average common stock equivalent price (the "Weighted-Average Price") below $13.42 per share, the exercise price of a Series Warrant shall reset upon exercise to the midpoint between the initial price and the lowest such Weighted-Average Price, but not below $6.71 per share. The exercise price may be adjusted only once pursuant to this mechanism.

F1 · price: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2 · ownership.nature: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
January 13, 2026 Filed Jan 15, 2026 17:00 UTC Foghorn Therapeutics Inc. FHTX · Entity 5820 GrantPre-Funded Warrants to purchase Common Stock · Derivative 2,235,468 $6.71 Strike: $0.00 $14,999,766.73
Disclosure

SEC source: 0001193125-26-014218 · ownership.xml · derivative · entry 1

Flagship Pioneering, LLC · CIK 0001400240 · Director · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · Director · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · Director · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · Director · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · Director · 10% owner

Flagship Ventures Fund V General Partner LLC · CIK 0001724575 · Director · 10% owner

Flagship Ventures Fund V, L.P. · CIK 0001627639 · Director · 10% owner

Flagship Ventures Opportunities Fund I General Partner LLC · CIK 0001725004 · Director · 10% owner

Flagship Ventures Opportunities Fund I, L.P. · CIK 0001677345 · Director · 10% owner

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 2,235,468

Underlying: Common Stock · 2,235,468 shares

Expires 2046-01-13

F1 · price: On January 13, 2026, pursuant to a registered direct offering by the Issuer, Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired warrants to purchase an aggregate of 4,470,936 shares of Common Stock, consisting of (i) Pre-Funded Warrants to purchase 2,235,468 shares of Common Stock, (ii) Series 1 Warrants to purchase 1,117,734 shares of Common Stock and (iii) Series 2 Warrants to purchase 1,117,734 shares of Common Stock (together with the Series 1 Warrants, the "Series Warrants"). The securities were acquired for a purchase price of $6.7099 per Pre-Funded Warrant and accompanying Series Warrants.

F2 · ownership.nature: Securities held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering, LLC (f/k/a Flagship Pioneering, Inc., "Flagship Pioneering") is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
July 11, 2023 Filed Jul 13, 2023 17:15 UTC Evelo Biosciences, Inc. EVLO · Entity 108468 PurchaseCommon Stock 3,246,753 $2.31 $7,499,999.43
Disclosure

SEC source: 0000950170-23-032871 · ownership.xml · nonDerivative · entry 3

Flagship Ventures Fund IV General Partner LLC · CIK 0001508051 · 10% owner

Flagship Ventures Fund IV, L.P. · CIK 0001503559 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Inc. · CIK 0001400240 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

AFEYAN NOUBAR · CIK 0001222012 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 3,931,685

F1 · kind: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F4 · ownership.nature: Shares held by Flagship Fund VII. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the reporting persons except for Flagship Fund VII disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Read SEC document
July 11, 2023 Filed Jul 13, 2023 17:15 UTC Evelo Biosciences, Inc. EVLO · Entity 108468 PurchaseCommon Stock 1,082,251 $2.31 $2,499,999.81
Disclosure

SEC source: 0000950170-23-032871 · ownership.xml · nonDerivative · entry 2

Flagship Ventures Fund IV General Partner LLC · CIK 0001508051 · 10% owner

Flagship Ventures Fund IV, L.P. · CIK 0001503559 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Inc. · CIK 0001400240 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

AFEYAN NOUBAR · CIK 0001222012 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 1,493,241

F1 · kind: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F3 · ownership.nature: Shares held by Nutritional LTP. Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering, Inc. ("Flagship Pioneering") is the manager of Nutritional LTP GP. Dr. Afeyan is the Chief Executive Officer, director and sole stockholder of Flagship Pioneering. Each of the reporting persons except for Nutritional LTP disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Read SEC document
July 11, 2023 Filed Jul 13, 2023 17:15 UTC Evelo Biosciences, Inc. EVLO · Entity 108468 PurchaseCommon Stock 1,082,251 $2.31 $2,499,999.81
Disclosure

SEC source: 0000950170-23-032871 · ownership.xml · nonDerivative · entry 1

Flagship Ventures Fund IV General Partner LLC · CIK 0001508051 · 10% owner

Flagship Ventures Fund IV, L.P. · CIK 0001503559 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Inc. · CIK 0001400240 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

AFEYAN NOUBAR · CIK 0001222012 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Ventures Fund IV, L.P.

Disclosed balance after: 1,461,795

F1 · kind: On July 11, 2023, Flagship Ventures Fund IV, L.P. ("Flagship Fund IV"), Nutritional Health LTP Fund, L.P. ("Nutritional LTP") and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") acquired 1,082,251 shares, 1,082,251 shares and 3,246,753 shares, respectively, of the Issuer's Common Stock in a private placement at a price of $2.31 per share.

F2 · ownership.nature: Shares held by Flagship Fund IV. Flagship Ventures Fund IV General Partner LLC ("Flagship Fund IV GP") is the general partner of Flagship Fund IV. Noubar B. Afeyan, Ph.D. ("Dr. Afeyan") is the sole manager of Flagship Fund IV GP. Each of the reporting persons except for Flagship Fund IV disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.