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Nasdaq · USD

GENB

Generate Biomedicines, Inc.

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Tapewire entity
1553
SEC CIK
0002100782
Parsed reports
34

Last 12 months

Inside the activity.

12 purchase rows · 1 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202600
Feb 202600
Mar 2026120
Apr 202600
May 202600
Jun 202600
Jul 202600
Aug 202600
Sep 202601
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
September 01, 2026 Filed Sep 3, 2026 20:05 UTC SaleCommon Stock 1,000 $16.00 $16,002.00
Disclosure

SEC source: 0001193125-26-381875 · ownership.xml · nonDerivative · entry 1

ARNOLD FRANCES · CIK 0001665419 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 231,472

F1 · kind: These transactions were effected by the Reporting Person pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 13, 2026.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $16.00 to $16.01 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 04, 2026 Filed Mar 6, 2026 21:55 UTC
Nally MichaelDirector · Chief Executive Officer
PurchaseCommon Stock 20,000 $12.00 $240,000.00
Disclosure

SEC source: 0001193125-26-096799 · ownership.xml · nonDerivative · entry 1

Nally Michael · CIK 0001763945 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 572,707

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries C Preferred Stock · Derivative 2,109,704 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 20

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,388,876 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries C Preferred Stock · Derivative 1,265,822 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 19

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 833,325 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries C Preferred Stock · Derivative 2,531,644 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 18

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,666,651 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries B Preferred Stock · Derivative 2,109,704 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 17

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,388,876 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries B Preferred Stock · Derivative 2,953,586 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 16

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,944,427 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries B Preferred Stock · Derivative 1,265,822 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 15

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 833,325 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries B Preferred Stock · Derivative 843,881 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 14

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 555,550 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries A Preferred Stock · Derivative 1,500,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 13

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 987,491 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4 · ownership.nature: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries A Preferred Stock · Derivative 17,016,215 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 12

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 11,202,248 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionSeries A Preferred Stock · Derivative 18,483,785 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 11

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 12,168,390 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 8

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Pioneering Medicines 02, LLC

Disclosed balance after: 1,562,500

F7 · ownership.nature: Securities held by Pioneering Medicine 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, is the sole manager of PM02, and Flagship Fund VII is its majority equity holder. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 7

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 4,340,252

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 6

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 15,264,724

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionCommon Stock 2,777,752 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 5

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 2,777,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionCommon Stock 2,777,752 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 4

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 2,777,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionCommon Stock 987,491 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 3

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 987,491

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4 · ownership.nature: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionCommon Stock 13,702,224 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 2

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 13,702,224

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
ConversionCommon Stock 12,723,940 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · nonDerivative · entry 1

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 12,723,940

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries C Preferred Stock · Derivative 2,109,704 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 20

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,388,876 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries C Preferred Stock · Derivative 1,265,822 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 19

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 833,325 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries C Preferred Stock · Derivative 2,531,644 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 18

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,666,651 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries B Preferred Stock · Derivative 2,109,704 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 17

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,388,876 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries B Preferred Stock · Derivative 2,953,586 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 16

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 1,944,427 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries B Preferred Stock · Derivative 1,265,822 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 15

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 833,325 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries B Preferred Stock · Derivative 843,881 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 14

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 555,550 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries A Preferred Stock · Derivative 1,500,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 13

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 987,491 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4 · ownership.nature: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries A Preferred Stock · Derivative 17,016,215 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 12

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 11,202,248 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionSeries A Preferred Stock · Derivative 18,483,785 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 11

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 12,168,390 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.exercise_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F1 · derivative.expiration_date: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 8

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Pioneering Medicines 02, LLC

Disclosed balance after: 1,562,500

F7 · ownership.nature: Securities held by Pioneering Medicine 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, is the sole manager of PM02, and Flagship Fund VII is its majority equity holder. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 7

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 4,340,252

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
PurchaseCommon Stock 1,562,500 $16.00 $25,000,000.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 6

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 15,264,724

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionCommon Stock 2,777,752 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 5

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By FPN II, L.P.

Disclosed balance after: 2,777,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F6 · ownership.nature: Securities held by FPN II, L.P. ("FPN II Fund"). FPN General Partner LLC ("FPN GP") is the general partner of FPN II Fund. Flagship Pioneering is the manager of FPN GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

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March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionCommon Stock 2,777,752 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 4

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Special Opportunities Fund II, L.P.

Disclosed balance after: 2,777,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F5 · ownership.nature: Securities held by Flagship Pioneering Special Opportunities Fund II, L.P. ("Flagship Opportunities Fund II"). Flagship Pioneering Special Opportunities Fund II General Partner LLC ("Flagship Opportunities Fund II GP") is the general partner of Flagship Opportunities Fund II. Flagship Pioneering is the manager of Flagship Opportunities Fund II GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

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March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionCommon Stock 987,491 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 3

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Nutritional Health LTP Fund, L.P.

Disclosed balance after: 987,491

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F4 · ownership.nature: Securities held by Nutritional Health LTP Fund, L.P. ("Nutritional LTP"). Nutritional Health LTP Fund General Partner LLC ("Nutritional LTP GP") is the general partner of Nutritional LTP. Flagship Pioneering is the manager of Nutritional LTP GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

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March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionCommon Stock 13,702,224 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 2

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VII, L.P.

Disclosed balance after: 13,702,224

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F3 · ownership.nature: Securities held by Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII"). Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

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March 02, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
ConversionCommon Stock 12,723,940 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · nonDerivative · entry 1

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Flagship Pioneering Fund VI, L.P.

Disclosed balance after: 12,723,940

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Securities held by Flagship Pioneering Fund VI, L.P. ("Flagship Fund VI"). Flagship Pioneering Fund VI General Partner LLC ("Flagship Fund VI GP") is the general partner of Flagship Fund VI. Flagship Pioneering, LLC ("Flagship Pioneering") is the manager of Flagship Fund VI GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. Each of the Reporting Persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein, if any.

F2 · ownership.nature: Each share of Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Preferred Stock had no expiration date.

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March 02, 2026 Filed Mar 2, 2026 17:47 UTC PurchaseCommon Stock 1,500 $16.00 $24,000.00
Disclosure

SEC source: 0001193125-26-085872 · ownership.xml · nonDerivative · entry 1

Mendillo Jane L · CIK 0001672424 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,500

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March 02, 2026 Filed Mar 2, 2026 22:50 UTC ConversionSeries A Preferred Stock · Derivative 1,100,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085881 · ownership.xml · derivative · entry 4

Bancel Stephane · CIK 0001443340 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By OCHA LLC

Disclosed balance after: 0

Underlying: Common Stock · 724,160 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F2 · ownership.nature: Shares held by OCHA LLC, of which the Reporting Person is the controlling unit holder and sole managing member. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such shares for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 22:50 UTC ConversionCommon Stock 724,160 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085881 · ownership.xml · nonDerivative · entry 1

Bancel Stephane · CIK 0001443340 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By OCHA LLC

Disclosed balance after: 724,160

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F2 · ownership.nature: Shares held by OCHA LLC, of which the Reporting Person is the controlling unit holder and sole managing member. The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such shares for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 22:50 UTC
Nally MichaelDirector · Chief Executive Officer
ConversionSeries A Preferred Stock · Derivative 1,000,000 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-085883 · ownership.xml · derivative · entry 6

Nally Michael · CIK 0001763945 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By MTN 2024 GST Trust

Disclosed balance after: 0

Underlying: Common Stock · 658,327 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F2 · ownership.nature: The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such shares for the purpose of Section 16 of the Exchange Act, or for any other purpose.

Read SEC document
March 02, 2026 Filed Mar 2, 2026 22:50 UTC
Nally MichaelDirector · Chief Executive Officer
ConversionCommon Stock 658,327 Not disclosed Not disclosed
Disclosure

SEC source: 0001193125-26-085883 · ownership.xml · nonDerivative · entry 1

Nally Michael · CIK 0001763945 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By MTN 2024 GST Trust

Disclosed balance after: 1,316,654

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Series A Preferred Stock automatically converted into shares of the Issuer's Common Stock on a one-for-1.5190 basis upon the closing of the Issuer's initial public offering on March 2, 2026. The Series A Preferred Stock had no expiration date.

F2 · ownership.nature: The Reporting Person disclaims beneficial ownership of such shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of his pecuniary interest therein, if any. This report shall not be deemed an admission that he is a beneficial owner of such shares for the purpose of Section 16 of the Exchange Act, or for any other purpose.

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March 02, 2026 Filed Mar 2, 2026 23:05 UTC
Grous BethChief People Officer
PurchaseCommon Stock 300 $16.00 $4,800.00
Disclosure

SEC source: 0001193125-26-085939 · ownership.xml · nonDerivative · entry 1

Grous Beth · CIK 0002109144 · Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · By Spouse

Disclosed balance after: 300

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March 02, 2026 Filed Mar 2, 2026 22:54 UTC
Silvers JasonPresident & CFO
PurchaseCommon Stock 1,000 $16.00 $16,000.00
Disclosure

SEC source: 0001193125-26-085898 · ownership.xml · nonDerivative · entry 3

Silvers Jason · CIK 0002109011 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Indirect · By son

Disclosed balance after: 1,000

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March 02, 2026 Filed Mar 2, 2026 22:54 UTC
Silvers JasonPresident & CFO
PurchaseCommon Stock 500 $16.00 $8,000.00
Disclosure

SEC source: 0001193125-26-085898 · ownership.xml · nonDerivative · entry 2

Silvers Jason · CIK 0002109011 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Indirect · By daughter

Disclosed balance after: 500

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March 02, 2026 Filed Mar 2, 2026 22:54 UTC
Silvers JasonPresident & CFO
PurchaseCommon Stock 500 $16.00 $8,000.00
Disclosure

SEC source: 0001193125-26-085898 · ownership.xml · nonDerivative · entry 1

Silvers Jason · CIK 0002109011 · President & CFO

10b5-1 filing: No plan indicated

Ownership: Indirect · By daughter

Disclosed balance after: 500

Read SEC document
February 26, 2026 Filed Mar 2, 2026 17:42 UTC
Afeyan NoubarDirector · 10% owner
FPN II, L.P.10% owner
GrantStock Option (Right to Buy) · Derivative 29,561 $0.00 Strike: $16.00 $0.00
Disclosure

SEC source: 0001193125-26-085855 · ownership.xml · derivative · entry 10

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship VentureLabs VI LLC · CIK 0001725008 · 10% owner

Flagship Pioneering Fund VI, L.P. · CIK 0001716926 · 10% owner

Flagship Pioneering Fund VII, L.P. · CIK 0001805916 · 10% owner

Nutritional Health LTP Fund, L.P. · CIK 0001780956 · 10% owner

Flagship Pioneering Special Opportunities Fund II, L.P. · CIK 0001761283 · 10% owner

FPN II, L.P. · CIK 0001918834 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,561

Underlying: Common Stock · 29,561 shares

Expires 2036-02-25

F9 · derivative.exercise_date: The shares underlying this option shall vest in full on February 19, 2027, subject to the Reporting Person's continued service on such vesting date.

Read SEC document
February 26, 2026 Filed Mar 2, 2026 17:52 UTC
Afeyan NoubarDirector · 10% owner
GrantStock Option (Right to Buy) · Derivative 29,561 $0.00 Strike: $16.00 $0.00
Disclosure

SEC source: 0001193125-26-085888 · ownership.xml · derivative · entry 10

AFEYAN NOUBAR · CIK 0001222012 · Director · 10% owner

Flagship Pioneering, LLC · CIK 0001400240 · 10% owner

Flagship VentureLabs VI Manager LLC · CIK 0001860060 · 10% owner

Flagship Pioneering Fund VI General Partner LLC · CIK 0001724957 · 10% owner

Flagship Pioneering Fund VII General Partner LLC · CIK 0001805917 · 10% owner

Nutritional Health LTP Fund General Partner LLC · CIK 0001780951 · 10% owner

Flagship Pioneering Special Opportunities Fund II General Partner LLC · CIK 0001826217 · 10% owner

FPN General Partner LLC · CIK 0001860059 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,561

Underlying: Common Stock · 29,561 shares

Expires 2036-02-25

F9 · derivative.exercise_date: The shares underlying this option shall vest in full on February 19, 2027, subject to the Reporting Person's continued service on such vesting date.

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February 26, 2026 Filed Mar 2, 2026 17:45 UTC GrantStock Option (Right to Buy) · Derivative 29,561 $0.00 Strike: $16.00 $0.00
Disclosure

SEC source: 0001193125-26-085861 · ownership.xml · derivative · entry 1

Parker Paul Gray · CIK 0001833033 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,561

Underlying: Common Stock · 29,561 shares

Expires 2036-02-25

F1 · derivative.exercise_date: The shares underlying this option shall vest in full on February 19, 2027, subject to the Reporting Person's continued service on such vesting date.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.