COOK JEREMY CURNOCK

SEC source: 0001216486-26-000002 · ownership.xml · derivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,133

Underlying: Common Stock · 16,133 shares

Expires 2036-01-20

F3 · derivative.exercise_price: On January 5, 2026, the Board of Directors approved a grant of 16,133 options to acquire 16,133 shares of Common Stock to each of its non-executive directors, with a grant date of January 20, 2026 (the "Grant Date") and an exercise price equal to the closing price of a share of Common Stock on Nasdaq on the Grant Date of $3.77. This option grant was subject to the approval of the Company's stockholders, which was obtained on June 3, 2026.

SEC source: 0001216486-26-000002 · ownership.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 62,050

F1 · price: Represents an award of restricted stock units (the "RSUs"), each RSU representing a contingent right to be issued one share of Common Stock of the Company (the "Common Stock"), that are subject to time-based vesting criteria. These RSUs vest on the date 12 months following the grant date of January 20, 2026. This grant of RSUs was subject to the approval of the Company's stockholders, which was obtained on June 3, 2026.

F2 · balance_after: Includes unvested RSUs.

SEC source: 0000950170-25-082428 · ownership.xml · derivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,295

Underlying: Common Stock · 4,295 shares

Expires 2035-01-21

F3 · derivative.exercise_price: On January 6, 2025, the Board of Directors approved a grant of 4,295 options to acquire 4,295 shares of Common Stock to each of its non-executive directors, with a grant date of January 21, 2025 (the "Grant Date") and an exercise price equal to the closing price of a share of Common Stock on Nasdaq on the Grant Date of $8.73. This option grant was subject to the approval of the Company's stockholders, which was obtained on June 4, 2025.

SEC source: 0000950170-25-082428 · ownership.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,836

F1 · price: Represents an award of restricted stock units (the "RSUs"), each RSU representing a contingent right to be issued one share of Common Stock of the Company (the "Common Stock"), that are subject to time-based vesting criteria. These RSUs vest on the date 12 months following the grant date of January 21, 2025. This grant of RSUs was subject to the approval of the Company's stockholders, which was obtained on June 4, 2025.

F2 · balance_after: Includes unvested RSUs.

SEC source: 0000950170-24-070114 · ownership.xml · derivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,943

Underlying: Common Stock · 3,943 shares

Expires 2034-06-05

SEC source: 0000950170-24-070114 · ownership.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,814

F1 · price: Represents an award of RSUs, each representing a contingent right to be issued one share of Common Stock, that are subject to time-based vesting criteria. These RSUs vest on the date 12 months following the grant date.

F2 · balance_after: Includes unvested RSUs.

SEC source: 0000950170-23-072730 · ownership.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,614

F1 · shares: Shares sold to cover UK tax obligation incurred by the Reporting Person upon the vesting of RSUs

F2 · shares: The original Form 4, filed on December 14, 2023, is being amended by this Form 4 to correct an administrative error, which misreported a sale of common stock to cover taxes for vesting of RSUs on the wrong date. The sale of the stock was reported on December 13, 2023, however, the actual sale occured on December 21, 2023. This Form 4 reflects the correction to the date, price and number of shares sold in the transaction.

F2 · price: The original Form 4, filed on December 14, 2023, is being amended by this Form 4 to correct an administrative error, which misreported a sale of common stock to cover taxes for vesting of RSUs on the wrong date. The sale of the stock was reported on December 13, 2023, however, the actual sale occured on December 21, 2023. This Form 4 reflects the correction to the date, price and number of shares sold in the transaction.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.39 to $12.64. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of the shares of Common Stock sold at each separate price within the ranges set forth in this footnote to this Form 4.

F2 · balance_after: The original Form 4, filed on December 14, 2023, is being amended by this Form 4 to correct an administrative error, which misreported a sale of common stock to cover taxes for vesting of RSUs on the wrong date. The sale of the stock was reported on December 13, 2023, however, the actual sale occured on December 21, 2023. This Form 4 reflects the correction to the date, price and number of shares sold in the transaction.

F4 · balance_after: Includes unvested RSUs

SEC source: 0000950170-23-070445 · ownership.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,596

F1 · shares: Shares only sold to cover UK tax obligation incurred by the Reporting Person upon the vesting of RSUs

F1 · price: Shares only sold to cover UK tax obligation incurred by the Reporting Person upon the vesting of RSUs

F2 · balance_after: Includes unvested RSUs

SEC source: 0001209191-23-035428 · doc4.xml · derivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,646

Underlying: Common Stock · 2,646 shares

Expires 2033-06-06

F1 · shares: The reporting person may elect to acquire the Issuer's CHESS Depositary Interests ("CDIs") in place of common stock upon vesting of a Restricted Stock Unit ("RSU") or exercise of a Stock Option. CDIs are units of beneficial ownership in shares of common stock of the Issuer that are publicly traded on the Australian Securities Exchange (the "ASX") and held by CHESS Depositary Nominees Pty, Limited, a subsidiary of ASX Limited, the company that operates the ASX. Five CDIs are equivalent to one share of common stock and have all the rights and privileges of common stock.

F4 · derivative.exercise_date: These Stock Options vest on the date 12 months following the grant date.

SEC source: 0001209191-23-035428 · doc4.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,114

F1 · shares: The reporting person may elect to acquire the Issuer's CHESS Depositary Interests ("CDIs") in place of common stock upon vesting of a Restricted Stock Unit ("RSU") or exercise of a Stock Option. CDIs are units of beneficial ownership in shares of common stock of the Issuer that are publicly traded on the Australian Securities Exchange (the "ASX") and held by CHESS Depositary Nominees Pty, Limited, a subsidiary of ASX Limited, the company that operates the ASX. Five CDIs are equivalent to one share of common stock and have all the rights and privileges of common stock.

F2 · price: Represents an award of RSUs, each representing a contingent right to be issued one share of Common Stock, that are subject to time-based vesting criteria. These RSUs vest on the date 12 months following the grant date.

F3 · balance_after: Includes unvested RSUs.

SEC source: 0001209191-22-061279 · doc4.xml · derivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,395

Underlying: Common Stock · 5,395 shares

Expires 2032-12-12

F3 · derivative.exercise_date: These Stock Options vest on the date 12 months following the grant date.

SEC source: 0001209191-22-061279 · doc4.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,939

F1 · price: Represents an award of Restricted Stock Units ("RSUs"), each representing a contingent right to be issued one share of Common Stock, that are subject to time-based vesting criteria. These RSUs vest on the date 12 months following the grant date.

F2 · balance_after: Includes unvested RSUs.

SEC source: 0001209191-21-071255 · doc4.xml · derivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,550

Underlying: Common Stock · 2,550 shares

Expires 2031-12-22

F3 · derivative.exercise_date: These Stock Options vest on the date 12 months following the grant date.

SEC source: 0001209191-21-071255 · doc4.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,350

F1 · price: Represents an award of Restricted Stock Units ("RSUs"), each representing a contingent right to be issued one share of Common Stock, that are subject to time-based vesting criteria. These RSUs vest on the date 12 months following the grant date.

F2 · balance_after: Includes unvested RSUs.

SEC source: 0001144204-19-028262 · tv522369_4.xml · derivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,383

Underlying: Common Stock · 27,383 shares

Expires 2029-05-22

F1 · derivative.exercise_date: The stock option vests as to fifty percent (50%) of the underlying shares of common stock on each annual anniversary of the date of grant.

SEC source: 0001104659-20-022092 · tm208184-5_form5.xml · derivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 46,666 shares

Expires 2021-11-22

F4 · derivative.exercise_price: Price reported is reflective of adjustments made after the date of issuance pursuant the terms of the warrant.

F1 · kind: The reported securities were redeemed by the issuer for $12,065.46.

F2 · derivative.underlying_shares: The number of shares of common stock for which the warrant was exercisable does not reflect the 1-for-14 reverse stock split that was effected on May 9, 2019.

F3 · ownership.nature: The warrant was held by One Funds Management Limited as Trustee for Asia Pacific Healthcare Fund II ("One Funds Management"). The Reporting Person may be deemed to have shared voting and dispositive power over the shares beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-18-021678 · doc4.xml · nonDerivative · entry 5

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 411,105

F2 · ownership.nature: The shares are held by One Funds Management Limited as Trustee for Asia Pacific Healthcare Fund II ("One Funds Management"). The Reporting Person may be deemed to have shared voting and dispositive power over the shares beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-18-021678 · doc4.xml · nonDerivative · entry 4

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 229,285

F1 · price: The Shares were issued pursuant to a Common Stock Issuance Agreement, dated April 8, 2016, between the Issuer and certain holders of the Issuer's Series B Preferred Stock (the "Holders"), as amended. As consideration for the Shares, among other things, the Holders waived their right to receive certain cash payments to which they were entitled upon the conversion of their Series B Preferred Stock and also waived certain registration rights relating to certain future registration statements or public offerings that may be filed or conducted by the Issuer.

F2 · ownership.nature: The shares are held by One Funds Management Limited as Trustee for Asia Pacific Healthcare Fund II ("One Funds Management"). The Reporting Person may be deemed to have shared voting and dispositive power over the shares beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-17-052310 · doc4.xml · derivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,900

Underlying: Common Stock · 10,900 shares

Expires 2027-09-06

SEC source: 0001209191-18-021678 · doc4.xml · nonDerivative · entry 3

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 124,270

F1 · price: The Shares were issued pursuant to a Common Stock Issuance Agreement, dated April 8, 2016, between the Issuer and certain holders of the Issuer's Series B Preferred Stock (the "Holders"), as amended. As consideration for the Shares, among other things, the Holders waived their right to receive certain cash payments to which they were entitled upon the conversion of their Series B Preferred Stock and also waived certain registration rights relating to certain future registration statements or public offerings that may be filed or conducted by the Issuer.

F2 · ownership.nature: The shares are held by One Funds Management Limited as Trustee for Asia Pacific Healthcare Fund II ("One Funds Management"). The Reporting Person may be deemed to have shared voting and dispositive power over the shares beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-18-021678 · doc4.xml · derivative · entry 7

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 46,666

Underlying: Common Stock · 46,666 shares

Expires 2021-11-22

F3 · derivative.exercise_price: Price reported is reflective of adjustments made to the exercise price after the date of issuance pursuant to the terms of the warrant.

F4 · derivative.exercise_date: Immediately exercisable.

F5 · ownership.nature: The warrant is held by One Funds Management. The Reporting Person may be deemed to have shared voting and dispositive power over the securities beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-18-021678 · doc4.xml · nonDerivative · entry 2

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 118,513

F2 · ownership.nature: The shares are held by One Funds Management Limited as Trustee for Asia Pacific Healthcare Fund II ("One Funds Management"). The Reporting Person may be deemed to have shared voting and dispositive power over the shares beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001209191-18-021678 · doc4.xml · nonDerivative · entry 1

COOK JEREMY CURNOCK · CIK 0001216486 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 71,847

F1 · price: The Shares were issued pursuant to a Common Stock Issuance Agreement, dated April 8, 2016, between the Issuer and certain holders of the Issuer's Series B Preferred Stock (the "Holders"), as amended. As consideration for the Shares, among other things, the Holders waived their right to receive certain cash payments to which they were entitled upon the conversion of their Series B Preferred Stock and also waived certain registration rights relating to certain future registration statements or public offerings that may be filed or conducted by the Issuer.

F2 · ownership.nature: The shares are held by One Funds Management Limited as Trustee for Asia Pacific Healthcare Fund II ("One Funds Management"). The Reporting Person may be deemed to have shared voting and dispositive power over the shares beneficially owned by One Funds Management but disclaims such beneficial ownership, except to the extent of his pecuniary interest therein, if any.