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person · Reporting owner

Lewis William

Disclosed activity across 3 companies

Tapewire entity
28834
SEC CIK
0001402051

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
INSMED IncINSM · Entity 3174Director · Chair and CEOJuly 23, 2026July 24, 2026
NewAmsterdam Pharma Co N.V.NAMS · Entity 1826DirectorJanuary 07, 2026January 10, 2026
uniQure N.V.QURE · Entity 4162DirectorJanuary 27, 2017January 31, 2017

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

INSMED Inc

Report date July 23, 2026 · Filed July 24, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect259,058 Ending reported balance After 2026-07-23 transaction · row 4
4 source rows · reconciled sequence

Row 1 · 2026-07-23 · Exercise / conversion · Acquired 6,260 · Balance 265,318

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Row 2 · 2026-07-23 · Exercise / conversion · Acquired 4,440 · Balance 269,758

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Row 3 · 2026-07-23 · Sale · Disposed 4,828 · Balance 264,930

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Row 4 · 2026-07-23 · Sale · Disposed 5,872 · Balance 259,058

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $30.46 · Expires 2028-01-04Direct0 Reported balance After 2026-07-23 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-07-23 · Exercise / conversion · Disposed 6,260 · Balance 0

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Stock Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $17.16 · Expires 2027-05-17Direct0 Reported balance After 2026-07-23 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-07-23 · Exercise / conversion · Disposed 4,440 · Balance 0

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Common StockSEC Table I · non-derivativeIndirectBy trust233,924 Reported balance Holding disclosure · report date 2026-07-23 · row 5 Holding and transaction disclosures are not merged.
1 source row

Row 5 · Balance 233,924

Filing footnotes · ownership attribution and instrument terms

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 4,828 shares sold at prices ranging from $105.09 to $106.02 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 5,872 shares sold at prices ranging from $106.09 to $106.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

NewAmsterdam Pharma Co N.V.

Report date January 07, 2026 · Filed January 10, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Ordinary SharesSEC Table I · non-derivativeDirect10,360 Reported balance After 2026-01-07 transaction · row 1
1 source row

Row 1 · 2026-01-07 · Grant · Acquired 3,400 · Balance 10,360

F1: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. All of the RSUs will vest on the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

F2: Each RSU was granted on January 7, 2026 for no consideration.

Option (right to buy)SEC Table II · derivative / convertible security · Conversion / exercise price $35.45 · Expires 2036-01-07Direct15,300 Reported balance After 2026-01-07 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2026-01-07 · Grant · Acquired 15,300 · Balance 15,300

F3: All of the ordinary shares underlying the option will vest on January 2, 2027, the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

Filing footnotes · ownership attribution and instrument terms

F1: Represents restricted stock units (RSUs), each representing a contingent right to receive one ordinary share. All of the RSUs will vest on the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

F2: Each RSU was granted on January 7, 2026 for no consideration.

F3: All of the ordinary shares underlying the option will vest on January 2, 2027, the one-year anniversary of the vesting start date, subject to the Reporting Person's continued service through such date.

uniQure N.V.

Report date January 27, 2017 · Filed January 31, 2017

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Stock Option (Right to Buy)SEC Table II · derivative / convertible security · Conversion / exercise price $5.37 · Expires 2027-01-27Direct11,000 Reported balance After 2017-01-27 transaction · row 1 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 1 · 2017-01-27 · Grant · Acquired 11,000 · Balance 11,000

F1: The Stock Option vests 100% on January 27, 2018.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct16,000 Reported balance After 2017-01-27 transaction · row 2 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 2 · 2017-01-27 · Grant · Acquired 11,000 · Balance 16,000

F2: The Restricted Stock Unit vests 100% on January 27, 2018.

F3: Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests.

Filing footnotes · ownership attribution and instrument terms

F1: The Stock Option vests 100% on January 27, 2018.

F2: The Restricted Stock Unit vests 100% on January 27, 2018.

F3: Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,080

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 43,814

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,434 $164.01 $235,190.34
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 1,434 shares sold at prices ranging from $163.66 to $164.36 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 8,478 $163.23 $1,383,863.94
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,619

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 8,478 shares sold at prices ranging from $162.66 to $163.65 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 787 $161.73 $127,281.51
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,097

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 787 shares sold at prices ranging from $161.65 to $162.58 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,884

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
April 06, 2026 Filed Apr 8, 2026 20:41 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000022 · wk-form4_1775680879.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,444

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,520

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · derivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 50,073

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,533 $144.11 $653,250.63
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 4,533 shares sold at prices ranging from $143.80 to $144.72 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,537 $143.42 $650,696.54
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 305,718

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 4,537 shares sold at prices ranging from $142.80 to $143.77 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,629 $142.17 $231,594.93
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 310,255

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 1,629 shares sold at prices ranging from $141.80 to $142.74 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,884

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 19, 2026 Filed Mar 20, 2026 20:05 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000020 · wk-form4_1774037117.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,444

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · derivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 39,960

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,332

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,128 $147.54 $313,965.12
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,128 shares sold at prices ranging from $147.15 to $148.04 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F6 · balance_after: The Reporting Person no longer has a reportable beneficial interest in the securities owned by the William Lewis Family Legacy Trust, which were included in the Reporting Person's prior ownership reports.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,899 $146.66 $571,827.34
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 303,313

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 3,899 shares sold at prices ranging from $146.09 to $147.06 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,589 $145.27 $376,104.03
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,212

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 2,589 shares sold at prices ranging from $144.99 to $145.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,083 $144.23 $300,431.09
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 309,801

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 2,083 shares sold at prices ranging from $143.84 to $144.70 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,884

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:16 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000018 · wk-form4_1772745408.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,444

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · derivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 44,400

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · derivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,591

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,030 $153.38 $157,981.40
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 1,030 shares sold at prices ranging from $153.00 to $153.78 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,377 $151.92 $361,113.84
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,215

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,377 shares sold at prices ranging from $151.56 to $152.43 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,413 $151.12 $515,772.56
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 304,592

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 3,413 shares sold at prices ranging from $150.54 to $151.51 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,891 $150.10 $283,839.10
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 308,005

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 1,891 shares sold at prices ranging from $149.53 to $150.50 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,988 $149.17 $296,549.96
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 309,896

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 1,988 shares sold at prices ranging from $148.51 to $149.50 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 311,884

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 19, 2026 Filed Feb 23, 2026 21:34 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000015 · wk-form4_1771882447.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,444

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · derivative · entry 9

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,850

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · derivative · entry 8

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,840

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,287 $148.83 $191,544.21
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 301,185

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 1,287 shares sold at prices ranging from $148.62 to $149.35 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 7,221 $148.02 $1,068,852.42
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 302,472

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 7,221 shares sold at prices ranging from $147.61 to $148.60 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 4,888 $147.17 $719,366.96
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 309,693

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 4,888 shares sold at prices ranging from $146.61 to $147.60 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 314,581

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 09, 2026 Filed Feb 11, 2026 21:42 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000013 · wk-form4_1770846139.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 308,322

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
February 03, 2026 Filed Feb 4, 2026 21:17 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 3,009 $156.34 $470,427.06
Disclosure

SEC source: 0001402051-26-000011 · wk-form4_1770239840.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 303,882

F1 · kind: Shares sold to satisfy tax withholding obligations upon the vesting of Restricted Stock Units and to cover related broker fees.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · derivative · entry 11

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 53,280

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · derivative · entry 10

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,109

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F7 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 254 $160.70 $40,817.80
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 7

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 306,891

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F6 · price: This is the weighted average sales price representing 254 shares sold at prices ranging from $160.58 to $160.76 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 2,229 $159.85 $356,305.65
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 6

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,145

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F5 · price: This is the weighted average sales price representing 2,229 shares sold at prices ranging from $159.55 to $160.32 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 5,967 $158.99 $948,693.33
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 5

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 309,374

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F4 · price: This is the weighted average sales price representing 5,967 shares sold at prices ranging from $158.55 to $159.52 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,243 $158.37 $196,853.91
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 4

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 315,341

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F3 · price: This is the weighted average sales price representing 1,243 shares sold at prices ranging from $157.54 to $158.53 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 SaleCommon Stock 1,006 $156.80 $157,740.80
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 3

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 316,584

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2 · price: This is the weighted average sales price representing 1,006 shares sold at prices ranging from $156.53 to $157.50 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 4,440 $17.16 $76,190.40
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 2

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 317,590

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
January 20, 2026 Filed Jan 22, 2026 21:28 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionCommon Stock 6,259 $30.46 $190,649.14
Disclosure

SEC source: 0001402051-26-000009 · wk-form4_1769117327.xml · nonDerivative · entry 1

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 313,150

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Read SEC document
January 12, 2026 Filed Jan 13, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 4,440 $0.00 Strike: $17.16 $0.00
Disclosure

SEC source: 0001402051-26-000007 · wk-form4_1768338242.xml · derivative · entry 13

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 57,720

Underlying: Common Stock · 4,440 shares

Expires 2027-05-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document
January 12, 2026 Filed Jan 13, 2026 21:04 UTC INSMED Inc INSM · Entity 3174 Exercise / conversionStock Option (right to buy) · Derivative 6,259 $0.00 Strike: $30.46 $0.00
Disclosure

SEC source: 0001402051-26-000007 · wk-form4_1768338242.xml · derivative · entry 12

Lewis William · CIK 0001402051 · Director · Chair and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 81,368

Underlying: Common Stock · 6,259 shares

Expires 2028-01-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 4, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F8 · derivative.exercise_date: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.