Foresite Capital Opportunity Fund V, L.P.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 15

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 195,776 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_price: Reflects a convertible note that is convertible into shares of Common Stock of the Issuer. The convertible note has a maturity date of June 17, 2027. The principal amount of the convertible note together with any accrued but unpaid interest automatically converted into shares of Common Stock of the Issuer upon the closing of the Issuer's initial public offering at a conversion price equal to the initial public offering price of the Issuer's common stock.

F5 · kind: Reflects a convertible note that is convertible into shares of Common Stock of the Issuer. The convertible note has a maturity date of June 17, 2027. The principal amount of the convertible note together with any accrued but unpaid interest automatically converted into shares of Common Stock of the Issuer upon the closing of the Issuer's initial public offering at a conversion price equal to the initial public offering price of the Issuer's common stock.

F5 · price: Reflects a convertible note that is convertible into shares of Common Stock of the Issuer. The convertible note has a maturity date of June 17, 2027. The principal amount of the convertible note together with any accrued but unpaid interest automatically converted into shares of Common Stock of the Issuer upon the closing of the Issuer's initial public offering at a conversion price equal to the initial public offering price of the Issuer's common stock.

F5 · derivative.exercise_date: Reflects a convertible note that is convertible into shares of Common Stock of the Issuer. The convertible note has a maturity date of June 17, 2027. The principal amount of the convertible note together with any accrued but unpaid interest automatically converted into shares of Common Stock of the Issuer upon the closing of the Issuer's initial public offering at a conversion price equal to the initial public offering price of the Issuer's common stock.

F5 · derivative.expiration_date: Reflects a convertible note that is convertible into shares of Common Stock of the Issuer. The convertible note has a maturity date of June 17, 2027. The principal amount of the convertible note together with any accrued but unpaid interest automatically converted into shares of Common Stock of the Issuer upon the closing of the Issuer's initial public offering at a conversion price equal to the initial public offering price of the Issuer's common stock.

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 14

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 296,880 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F4 · ownership.nature: The securities are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over the shares held by Opportunity Fund V. Tananbaum is the sole managing member of FCOM V and may be deemed to have sole voting and dispositive power over the securities held by Opportunity Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 13

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 3,117,664 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F4 · ownership.nature: The securities are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over the shares held by Opportunity Fund V. Tananbaum is the sole managing member of FCOM V and may be deemed to have sole voting and dispositive power over the securities held by Opportunity Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 12

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 742,201 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 11

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 1,125,823 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 10

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 445,320 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F2 · ownership.nature: The securities are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. James B. Tananbaum (Tananbaum) is the sole managing member of FCM V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · derivative · entry 9

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 3,117,664 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.exercise_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F1 · derivative.expiration_date: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F2 · ownership.nature: The securities are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. James B. Tananbaum (Tananbaum) is the sole managing member of FCM V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 8

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 3,414,544

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F4 · ownership.nature: The securities are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over the shares held by Opportunity Fund V. Tananbaum is the sole managing member of FCOM V and may be deemed to have sole voting and dispositive power over the securities held by Opportunity Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 7

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 3,117,664

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F4 · ownership.nature: The securities are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over the shares held by Opportunity Fund V. Tananbaum is the sole managing member of FCOM V and may be deemed to have sole voting and dispositive power over the securities held by Opportunity Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 6

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 2,203,800

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F5 · price: Reflects a convertible note that is convertible into shares of Common Stock of the Issuer. The convertible note has a maturity date of June 17, 2027. The principal amount of the convertible note together with any accrued but unpaid interest automatically converted into shares of Common Stock of the Issuer upon the closing of the Issuer's initial public offering at a conversion price equal to the initial public offering price of the Issuer's common stock.

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 5

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 2,008,024

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 4

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,868,024

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 3

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,125,823

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F3 · ownership.nature: The securities are held of record by Foresite Capital Fund VI LP ("Fund VI"). Foresite Capital Management VI, LLC ("FCM VI") is the general partner of Fund VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Tananbaum is the sole managing member of FCM VI and may be deemed to have sole voting and dispositive power over the securities held by Fund VI. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 2

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 3,562,984

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F2 · ownership.nature: The securities are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. James B. Tananbaum (Tananbaum) is the sole managing member of FCM V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-093580 · tm2622773-1_4seq1.xml · nonDerivative · entry 1

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 3,117,664

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Each share of the Issuer's preferred stock converted automatically into 1 share of common stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The preferred stock had no expiration date.

F2 · ownership.nature: The securities are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. James B. Tananbaum (Tananbaum) is the sole managing member of FCM V and may be deemed to have sole voting and dispositive power over the securities held by Fund V. Each of the Reporting Persons disclaims the existence of a "group" and disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein.

SEC source: 0001104659-26-039610 · tm2611109-2_4seq1.xml · nonDerivative · entry 4

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Labs Co-Invest V, LLC · CIK 0001810063 · 10% owner

Foresite Labs Management I, LLC · CIK 0001848577 · 10% owner

Foresite Labs Fund I, L.P. · CIK 0001848472 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 680,486

F6 · kind: Represents shares received by TFL Investment Holdings, LLC ("TFL"). pursuant to pro rata distributions by Labs, for no consideration, to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Exchange Act.

F7 · ownership.nature: The shares are held of record by TFL. Tananbaum is the manager of TFL, and James B. Tananbaum and Dana Shonfeld Tananbaum Family Trust, of which Tananbaum is a trustee, is the sole member of TFL. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that any such person is the beneficial owner of such securities, except to the extent of such person's pecuniary interest therein, if any.

SEC source: 0001104659-26-039610 · tm2611109-2_4seq1.xml · nonDerivative · entry 3

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Labs Co-Invest V, LLC · CIK 0001810063 · 10% owner

Foresite Labs Management I, LLC · CIK 0001848577 · 10% owner

Foresite Labs Fund I, L.P. · CIK 0001848472 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F5 · kind: Represents a pro rata, in-kind distribution, and not a purchase or sale, without additional consideration by Labs to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Exchange Act.

F4 · ownership.nature: The shares are held of record by Labs. Tananbaum, a manager of Labs, may be deemed to share voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-039610 · tm2611109-2_4seq1.xml · nonDerivative · entry 2

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Labs Co-Invest V, LLC · CIK 0001810063 · 10% owner

Foresite Labs Management I, LLC · CIK 0001848577 · 10% owner

Foresite Labs Fund I, L.P. · CIK 0001848472 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,123,337

F3 · kind: Represents shares received by Labs pursuant to pro rata distributions by Labs Affiliates, for no consideration, to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Exchange Act.

F4 · ownership.nature: The shares are held of record by Labs. Tananbaum, a manager of Labs, may be deemed to share voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-039610 · tm2611109-2_4seq1.xml · nonDerivative · entry 1

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Labs Co-Invest V, LLC · CIK 0001810063 · 10% owner

Foresite Labs Management I, LLC · CIK 0001848577 · 10% owner

Foresite Labs Fund I, L.P. · CIK 0001848472 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F1 · kind: Represents a pro rata, in-kind distribution, and not a purchase or sale, without additional consideration by Foresite Labs Affiliates 2021, LLC ("Labs Affiliates") to its members in accordance with the exemptions afforded by Rules 16a-13 and/or 16a-9 of the Securities Exchange Act of 1934, as amended (the "Exchange Act").

F2 · ownership.nature: The shares are held of record by Labs Affiliates. Foresite Labs, LLC ("Labs") is the managing member of Labs Affiliates and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), a manager of Labs, may be deemed to share voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and disclaims beneficial ownership of the shares held by Labs Affiliates, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 29

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 458,855 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 28

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 229,428 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 27

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 38,133 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 26

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 67,207 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 25

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 922 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 24

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 1,626 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 23

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 408,725 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F5 · ownership.nature: The shares are held of record by Foresite Capital VI-A, LLC ("Fund VI-A"). Foresite Capital VI-A Management, LLC ("FC VI-A Management") is the general partner of Fund VI-A and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FC VI-A Management, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Fund VI-A, disclaims beneficial ownership of the shares held by Fund VI-A, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 22

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 37,855 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 21

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 37,855 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 20

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 37,855 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 19

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 348,942 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 18

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 697,885 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 17

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 335,521 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · derivative · entry 16

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 0

Underlying: Common Stock · 1,340,878 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.exercise_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F1 · derivative.expiration_date: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 15

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,318,983

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 14

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 408,725

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F5 · ownership.nature: The shares are held of record by Foresite Capital VI-A, LLC ("Fund VI-A"). Foresite Capital VI-A Management, LLC ("FC VI-A Management") is the general partner of Fund VI-A and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FC VI-A Management, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Fund VI-A, disclaims beneficial ownership of the shares held by Fund VI-A, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 13

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 425,852

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 12

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 387,719

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 11

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 386,797

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 10

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 348,942

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F4 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 9

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,263,428

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 8

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 804,573

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 7

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 737,366

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 6

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 735,740

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 5

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 697,885

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F3 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 4

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,943,682

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 3

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,714,254

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 2

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,676,399

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-011662 · tm265543-1_4seq1.xml · nonDerivative · entry 1

Foresite Capital Management IV, LLC · CIK 0001704132 · 10% owner

Foresite Capital Fund IV, L.P. · CIK 0001704131 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital VI-A Management, LLC · CIK 0001899218 · 10% owner

Foresite Capital VI-A, LLC · CIK 0001899120 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 1,340,878

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of Common Stock and has no expiration date.

F2 · ownership.nature: The shares are held of record by Foresite Capital Fund IV, L.P. ("Fund IV"). Foresite Capital Management IV, LLC ("FCM IV") is the general partner of Fund IV and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Fund IV, disclaims beneficial ownership of the shares held by Fund IV, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-003017 · tm263003-2_4seq1.xml · nonDerivative · entry 2

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Labs Co-Invest V, LLC · CIK 0001810063 · 10% owner

Foresite Labs Management I, LLC · CIK 0001848577 · 10% owner

Foresite Labs Fund I, L.P. · CIK 0001848472 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 2,908,332

F2 · ownership.nature: The shares are held of record by Foresite Capital Opportunity Fund V, L.P. ("Opportunity Fund V"). Foresite Capital Opportunity Management V, LLC ("FCOM V") is the general partner of Opportunity Fund V and may be deemed to have sole voting and dispositive power over such shares. Tananbaum, the managing member of FCOM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and, other than Opportunity Fund V, disclaims beneficial ownership of the shares held by Opportunity Fund V, except to the extent of such person's pecuniary interest in such securities.

SEC source: 0001104659-26-003017 · tm263003-2_4seq1.xml · nonDerivative · entry 1

Foresite Capital Management VI LLC · CIK 0002013341 · 10% owner

Foresite Capital Management V, LLC · CIK 0001792206 · 10% owner

Foresite Capital Fund V, L.P. · CIK 0001792204 · 10% owner

Foresite Capital Opportunity Management V, LLC · CIK 0001792207 · 10% owner

Foresite Capital Opportunity Fund V, L.P. · CIK 0001792205 · 10% owner

Foresite Capital Fund VI LP · CIK 0001932516 · 10% owner

Labs Co-Invest V, LLC · CIK 0001810063 · 10% owner

Foresite Labs Management I, LLC · CIK 0001848577 · 10% owner

Foresite Labs Fund I, L.P. · CIK 0001848472 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnote

Disclosed balance after: 5,702,536

F1 · ownership.nature: The shares are held of record by Foresite Capital Fund V, L.P. ("Fund V"). Foresite Capital Management V, LLC ("FCM V") is the general partner of Fund V and may be deemed to have sole voting and dispositive power over such shares. James B. Tananbaum ("Tananbaum"), the managing member of FCM V, may be deemed to have sole voting and dispositive power over such shares. Each of the Reporting Persons disclaims the existence of a "group", as defined in Rule 13d-5 of the Exchange Act, and, other than Fund V, disclaims beneficial ownership of the shares held by Fund V, except to the extent of such person's pecuniary interest in such securities.