Kirby John J.

SEC source: 0001556327-26-000003 · form4-08182026_050806.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,962

F1 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $4.85 to $4.99 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

SEC source: 0001556327-25-000006 · form4-12302025_081201.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,962

F1 · shares: Represents a fully vested restricted stock unit award.

SEC source: 0001556327-25-000004 · form4-11252025_071111.xml · derivative · entry 2

Kirby John J. · CIK 0001556327 · Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 884

Underlying: Common Stock · 884 shares

Expires 2030-11-25

F3 · price: The reported securities are included within 3,536 investment units purchased by the Reporting Person for $4.2425 per investment unit. Each investment unit consists of one share of Common Stock and a Series C warrant for one fourth of a share of common stock. The Reporting Person will not be entitled to exercise any portion of a Series C Warrant that, upon giving effect to such exercise, would cause the aggregate number of shares beneficially owned by the Reporting Person to exceed 9.99% of the number of shares of the Issuer's common stock outstanding immediately after giving effect to the exercise.

F2 · derivative.exercise_date: Immediately exercisable.

SEC source: 0001556327-25-000004 · form4-11252025_071111.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,962

F1 · balance_after: Effective July 24, 2025, the Issuer effected a 1-for-10 reverse stock split of the Issuer's common stock. The number of securities reported herein have been adjusted to reflect the reverse stock split.

SEC source: 0001415889-24-026290 · form4-11072024_021129.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Interim CFO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,267

F1 · shares: Represents a restricted stock unit ("RSU") award. The RSUs shall vest vest in full on May 4, 2025, subject to the Reporting Person's continuous service through such date.

SEC source: 0001415889-23-001859 · form4-02032023_010245.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,400

Underlying: Common Stock · 25,400 shares

Expires 2033-01-20

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2022 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on January 20, 2023. Twenty-five percent (25%) of the stock option vests and becomes exercisable on January 20, 2024 (first anniversary of the date of grant) and the balance vests in thirty-six equal monthly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001415889-23-000764 · form4-01112023_020116.xml · nonDerivative · entry 2

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 316,893

F2 · shares: Represents the number of shares withheld by Issuer to cover tax obligations in connection with the grant of the shares of common stock.

SEC source: 0001415889-23-000764 · form4-01112023_020116.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 436,850

F1 · shares: Represents shares of common stock granted under the Idera Pharmaceuticals, Inc. 2013 Stock Incentive Plan, as amended and restated. The shares were granted pursuant to that certain Employment Continuation and Retention Bonus Letter Agreement, dated as of September 28, 2022, between the Issuer and Reporting Person.

SEC source: 0001415889-22-007540 · form4-07072022_020708.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,500

Underlying: Common Stock · 66,500 shares

Expires 2032-07-06

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option will vest and become exercisable in full on July 6, 2026, with 25% vesting on July 6, 2023, and the remainder vesting in twelve equal quarterly installments over the remaining three years, subject to continued service with the Issuer.

SEC source: 0001415889-22-003753 · form4-04042022_020415.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,500

Underlying: Common Stock · 41,500 shares

Expires 2032-04-01

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option will vest and become exercisable in full on January 24, 2026, with 25% vesting on January 24, 2023, and the remainder vesting in twelve equal quarterly installments over the remaining three years, subject to continued service with the Issuer.

SEC source: 0001415889-22-000791 · form4-01262022_050107.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 25,000 shares

Expires 2032-01-24

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on January 24, 2022. Twenty-five percent (25%) of the stock option vests and becomes exercisable on January 24, 2023 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001415889-21-006155 · form4-12212021_041212.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,632

SEC source: 0001415889-21-003584 · form4-07122021_040701.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,500

Underlying: Common Stock · 66,500 shares

Expires 2031-07-08

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on July 8, 2021. Twenty-five percent (25%) of the stock option vests and becomes exercisable on July 8, 2022 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001415889-21-001670 · form4-03292021_010319.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,632

F1 · shares: Restricted Stock Units ("RSUs") granted to Reporting Person on January 3, 2019 and January 10, 2020 were accelerated and became fully vested on March 23, 2021. The amount reported in Column 4 represents the number of shares of Issuer common stock required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of 20,125 RSUs on March 23, 2021. This sale is mandated by the Issuer's election under its 2013 Stock Incentive Plan to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

SEC source: 0001179110-21-000563 · edgar.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,882

F1 · shares: Represents the number of shares of Issuer common stock required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of 5,000 Restricted Stock Units ("RSUs") on January 10, 2021. This sale is mandated by the Issuer's election under its 2013 Stock Incentive Plan to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · price: The reported price in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from 4.205 to $4.232 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · balance_after: Of the reported securities beneficially owned, 20,125 shares are represented by unvested RSUs.

SEC source: 0001179110-21-000563 · edgar.xml · derivative · entry 2

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,000

Underlying: Common Stock · 51,000 shares

Expires 2031-01-08

F4 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on January 8, 2021. Twenty-five percent (25%) of the stock option vests and becomes exercisable on January 8, 2022 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001179110-21-000338 · edgar.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,575

F1 · shares: Represents the number of shares of Issuer common stock required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of 2,563 Restricted Stock Units ("RSUs") on January 3, 2021. This sale is mandated by the Issuer's election under its 2013 Stock Incentive Plan to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Of the reported securities beneficially owned, 25,125 shares are represented by unvested RSUs.

SEC source: 0001179110-20-008429 · edgar.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2030-07-21

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on July 21, 2020. Twenty-five percent (25%) of the stock option vests and becomes exercisable on July 21, 2021 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001179110-20-000563 · edgar.xml · derivative · entry 2

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 50,000

Underlying: Common Stock · 50,000 shares

Expires 2030-01-10

F3 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on January 10, 2020. Twenty-five percent (25%) of the stock option vests and becomes exercisable on January 10, 2021 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001179110-20-000563 · edgar.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,437

F1 · shares: Represents a restricted stock unit ("RSU") award granted under the Issuer's 2013 Stock Incentive Plan. Each RSU represents a right to receive one share of Issuer common stock. The RSU award vests over a four-year period commencing on January 10, 2020. Twenty-five percent (25%) of the shares subject to the RSU award shall vest on each one-year anniversary of the grant date of the award.

F2 · balance_after: Securities beneficially owned totaling 36,437 includes 8,749 shares of Issuer common stock owned and 27,688 of unvested RSU's held by the reporting person.

SEC source: 0001179110-20-000448 · edgar.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,437

F1 · shares: Represents the number of shares of Issuer common stock required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of 2,562 Restricted Stock Units ("RSUs") on January 3, 2020. This sale is mandated by the Issuer's election under its 2013 Stock Incentive Plan to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F2 · price: The reported price in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $1.76 to $1.82 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · balance_after: Of the reported shares, 7,688 shares are represented by unvested RSUs.

SEC source: 0001179110-20-000557 · edgar.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,437

F1 · deemedExecutionDate: The Form 4 filed on January 10, 2020 did not include the Deemed Execution Date in Column 2A and corresponding footnote disclosure. This amendment to the Form 4 is being filed to include this information for the reported transaction.

F2 · deemedExecutionDate: In accordance with terms of the RSU agreement, the "sell to cover" provision is intended to comply with the requirements of Rule 10b5-1(c)(1) under the Exchange Act and be interpreted to comply with the requirements of Rule 10b5-1(c) under the Exchange Act.

F3 · shares: Represents the number of shares of Issuer common stock required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of 2,562 Restricted Stock Units ("RSUs") on January 3, 2020. This sale is mandated by the Issuer's election under its 2013 Stock Incentive Plan to require the satisfaction of tax withholding obligations to be funded by a "sell to cover" transaction and does not represent a discretionary trade by the Reporting Person.

F4 · price: The reported price in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $1.76 to $1.82 per share. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F5 · balance_after: Of the reported shares, 7,688 shares are represented by unvested RSUs.

SEC source: 0001179110-19-008597 · edgar.xml · derivative · entry 1

Kirby John J. · CIK 0001556327 · VP of Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,500

Underlying: Common Stock · 45,500 shares

Expires 2029-07-09

F1 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on July 9, 2019. Twenty-five percent (25%) of the stock option vests and becomes exercisable on July 9, 2020 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001179110-19-000530 · edgar.xml · derivative · entry 2

Kirby John J. · CIK 0001556327 · VP of Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,600

Underlying: Common Stock · 25,600 shares

Expires 2029-01-03

F3 · derivative.exercise_date: The stock option award was granted under the Issuer's 2013 Stock Incentive Plan. The stock option vests and becomes exercisable over a four-year period commencing on January 3, 2019. Twenty-five percent (25%) of the stock option vests and becomes exercisable on January 3, 2020 (first anniversary of the date of grant) and the balance vests in twelve equal quarterly installments over the remaining three years of the four-year period, subject to continued service with the Issuer.

SEC source: 0001179110-19-000530 · edgar.xml · nonDerivative · entry 1

Kirby John J. · CIK 0001556327 · VP of Finance

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,509

F1 · shares: Represents a restricted stock unit ("RSU") award granted under the Issuer's 2013 Stock Incentive Plan. Each RSU represents a right to receive one share of Issuer common stock. The RSU award vests over a four-year period commencing on January 3, 2019. Twenty-five percent (25%) of the shares subject to the RSU award shall vest on each one-year anniversary of the grant date of the award.

F2 · balance_after: Securities beneficially owned totaling 12,509 includes 2,259 shares of Issuer common stock owned and 10,250 of unvested RSU's held by the reporting person.