PARMAR KUSH

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 5

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures II, L.P.

Disclosed balance after: 1,679,685

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: The securities are directly held by 5AM Ventures II, L.P. ("Ventures II"). 5AM Partners II, LLC ("Partners II") is the sole general partner of Ventures II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 4

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,167,206

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.05 to $6.11 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 3

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Co-Investors II, L.P.

Disclosed balance after: 66,356

F3 · ownership.nature: The securities are directly held by 5AM Co-Investors II, L.P. ("Co-Investors II"). Partners II is the sole general partner of Co-Investors II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Co-Investors II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 2

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures II, L.P.

Disclosed balance after: 1,681,685

F2 · ownership.nature: The securities are directly held by 5AM Ventures II, L.P. ("Ventures II"). 5AM Partners II, LLC ("Partners II") is the sole general partner of Ventures II. Dr. John Diekman, Andrew J. Schwab and Dr. Scott M. Rocklage are the managing members of Partners II and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures II. Each of Partners II, Dr. Diekman and Dr. Rocklage disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-023399 · form4-09132024_100903.xml · nonDerivative · entry 1

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,178,964

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-020035 · form4-07242024_040705.xml · derivative · entry 6

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 214,692 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F1 · price: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-020035 · form4-07242024_040705.xml · derivative · entry 5

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 843,592 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F1 · price: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-020035 · form4-07242024_040705.xml · nonDerivative · entry 4

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Opportunities II, L.P.

Disclosed balance after: 1,182,054

F5 · ownership.nature: Shares are held by 5AM Opportunities II, L.P. ("Opportunities II"). 5AM Opportunities II (GP), LLC ("Opportunities II GP") is the general partner of Opportunities II and may be deemed to have sole investment and voting power over the shares held by Opportunities II. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Opportunities II GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities II. Each of Opportunities II GP, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-020035 · form4-07242024_040705.xml · nonDerivative · entry 3

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Opportunities II, L.P.

Disclosed balance after: 348,721

F4 · kind: Represents the conversion of outstanding simple agreement for future equity in the amount of $3,556,957.78 into shares of the Issuer's common stock upon closing of the Issuer's IPO at a 15% discount to the IPO price.

F5 · ownership.nature: Shares are held by 5AM Opportunities II, L.P. ("Opportunities II"). 5AM Opportunities II (GP), LLC ("Opportunities II GP") is the general partner of Opportunities II and may be deemed to have sole investment and voting power over the shares held by Opportunities II. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Opportunities II GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities II. Each of Opportunities II GP, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-020035 · form4-07242024_040705.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 1,171,250

F3 · kind: Represents the conversion of outstanding simple agreement for future equity in the amount of $1,152,253.93 into shares of the Issuer's common stock upon closing of the Issuer's IPO at a 15% discount to the IPO price.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-020035 · form4-07242024_040705.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 1,058,284

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each share of Series A Preferred Stock and Series B Preferred Stock (collectively, the "Preferred Stock") converted into shares of Common Stock of the Issuer on a one-for-one basis without payment of further consideration. Upon the closing of the Issuer's initial public offering (the "IPO"), the Preferred Stock was converted into the number of shares of Common Stock of the Issuer shown in column 7 of Table II. The Preferred Stock had no expiration date.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001689375-24-000038 · wk-form4_1718397557.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2034-06-13

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable on the earlier of (i) the one-year anniversary of June 13, 2024 or (ii) the Issuer's next annual meeting of stockholders.

SEC source: 0001739410-24-000091 · wk-form4_1715979881.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,500

Underlying: Common Stock · 16,500 shares

Expires 2034-05-15

F1 · derivative.exercise_date: The option was granted under the Company's 2021 Equity Incentive Plan. The option vests on the earlier of May 15, 2025 or the date of the Company's 2025 Annual Meeting of Stockholders.

SEC source: 0001415889-24-008107 · form4-03152024_040305.xml · nonDerivative · entry 1

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 8,393,520

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-004111 · form4-02162024_040204.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 635,341

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.89 to $14.93 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The shares are directly held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares, except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-004111 · form4-02162024_040204.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AMVentures VI, L.P.

Disclosed balance after: 3,200,634

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $14.89 to $14.93 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001209191-24-002643 · doc4.xml · nonDerivative · entry 1

5AM Partners VII, LLC · CIK 0001873545 · 10% owner

5AM Ventures VII, L.P. · CIK 0001844435 · 10% owner

5AM Partners II, LLC · CIK 0001555952 · 10% owner

5AM Ventures II LP · CIK 0001386509 · 10% owner

5AM CO-INVESTORS II LP · CIK 0001390376 · 10% owner

DIEKMAN JOHN D · CIK 0001240357 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

ROCKLAGE SCOTT M · CIK 0001219014 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VII, L.P.

Disclosed balance after: 7,943,520

F1 · ownership.nature: The securities are directly held by 5AM Ventures VII, L.P. ("Ventures VII"). 5AM Partners VII, LLC ("Partners VII") is the sole general partner of Ventures VII. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VII and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VII. Each of Partners VII and Dr. Parmar disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein. Mr. Schwab is a director of the Issuer and files separate Section 16 reports.

SEC source: 0001415889-24-002295 · form4-02022024_090230.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 771,983

F2 · ownership.nature: The shares are directly held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares, except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001415889-24-002295 · form4-02022024_090230.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AMVentures VI, L.P.

Disclosed balance after: 3,888,992

F1 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001739410-24-000004 · wk-form4_1704409080.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,118

Underlying: Common Stock · 27,118 shares

Expires 2034-01-02

F2 · price: This option was issued to the reporting person pursuant to the Company's 2021 Equity Incentive Plan in lieu of retainer fees of $48,000.

F1 · derivative.exercise_date: The option vests as to the underlying shares of Common Stock in 12 equal installments, each on the last day of each month of calendar year 2024.

SEC source: 0001209191-23-050731 · doc4.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 854,796

F2 · ownership.nature: The shares are directly held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares, except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001209191-23-050731 · doc4.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 4,306,179

F1 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001209191-23-047514 · doc4.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 887,507

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00 to $16.60 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The shares are directly held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares, except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001209191-23-047514 · doc4.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 4,470,968

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00 to $16.60 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his respective pecuniary interest therein.

SEC source: 0001104659-23-070338 · tm2318445-4_4seq1.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2033-06-08

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable on the earlier of (i) the one-year anniversary of June 8, 2023 (the "Vesting Start Date") or (ii) the Issuer's next annual meeting of stockholders.

SEC source: 0000899243-23-013407 · doc4.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,490

Underlying: Common Stock · 15,490 shares

Expires 2033-05-17

F1 · derivative.exercise_date: The option was granted under the Company's 2021 Equity Incentive Plan. The option vests on the earlier of May 17, 2024 or the date of the Company's 2024 Annual Meeting of Stockholders.

SEC source: 0001209191-23-017538 · doc4.xml · nonDerivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures V, L.P.

Disclosed balance after: 2,378,969

F1 · ownership.nature: These securities are held directly by 5AM Ventures V, L.P. ("Ventures V"). 5AM Partners V, LLC ("Partners V") is the sole general partner of Ventures V. Dr. Parmar is a managing member of Partners V and may be deemed to share voting and investment power over the securities held by Ventures V. Dr. Parmar disclaims beneficial ownership of the securities held by Ventures V except to the extent of his pecuniary interest therein.

SEC source: 0001209191-23-013671 · doc4.xml · nonDerivative · entry 3

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 0

F1 · shares: Pursuant to the Agreement and Plan of Merger (the "Merger Agreement"), dated as of January 8, 2023, by and among CinCor Pharma, Inc. (the "Issuer"), AstraZeneca Finance and Holdings Inc. ("Parent") and Cinnamon Acquisition, Inc., a wholly owned subsidiary of Parent ("Purchaser"), on February 24, 2023, Purchaser completed a tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the "Merger"). At the effective time of the Merger, each issued and outstanding Share was cancelled in exchange for (i) $26.00 per Share in cash (the "Cash Amount"), plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per share, [continues to footnote (2)]

F2 · shares: [continues from footnote (1)] in cash, upon the achievement of a specified milestone by December 31, 2033 (the Cash Amount plus one CVR, collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes. Pursuant to the terms of the Merger Agreement, the Shares were tendered and disposed of at the Offer Acceptance Time (as defined in the Merger Agreement) in exchange for the right to receive the Offer Price.

F1 · price: Pursuant to the Agreement and Plan of Merger (the "Merger Agreement"), dated as of January 8, 2023, by and among CinCor Pharma, Inc. (the "Issuer"), AstraZeneca Finance and Holdings Inc. ("Parent") and Cinnamon Acquisition, Inc., a wholly owned subsidiary of Parent ("Purchaser"), on February 24, 2023, Purchaser completed a tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the "Merger"). At the effective time of the Merger, each issued and outstanding Share was cancelled in exchange for (i) $26.00 per Share in cash (the "Cash Amount"), plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per share, [continues to footnote (2)]

F2 · price: [continues from footnote (1)] in cash, upon the achievement of a specified milestone by December 31, 2033 (the Cash Amount plus one CVR, collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes. Pursuant to the terms of the Merger Agreement, the Shares were tendered and disposed of at the Offer Acceptance Time (as defined in the Merger Agreement) in exchange for the right to receive the Offer Price.

F5 · ownership.nature: Shares are held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP, Mr. Schwab and Dr. Parmar disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0001209191-23-013671 · doc4.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Opportunities II, L.P.

Disclosed balance after: 0

F1 · shares: Pursuant to the Agreement and Plan of Merger (the "Merger Agreement"), dated as of January 8, 2023, by and among CinCor Pharma, Inc. (the "Issuer"), AstraZeneca Finance and Holdings Inc. ("Parent") and Cinnamon Acquisition, Inc., a wholly owned subsidiary of Parent ("Purchaser"), on February 24, 2023, Purchaser completed a tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the "Merger"). At the effective time of the Merger, each issued and outstanding Share was cancelled in exchange for (i) $26.00 per Share in cash (the "Cash Amount"), plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per share, [continues to footnote (2)]

F2 · shares: [continues from footnote (1)] in cash, upon the achievement of a specified milestone by December 31, 2033 (the Cash Amount plus one CVR, collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes. Pursuant to the terms of the Merger Agreement, the Shares were tendered and disposed of at the Offer Acceptance Time (as defined in the Merger Agreement) in exchange for the right to receive the Offer Price.

F1 · price: Pursuant to the Agreement and Plan of Merger (the "Merger Agreement"), dated as of January 8, 2023, by and among CinCor Pharma, Inc. (the "Issuer"), AstraZeneca Finance and Holdings Inc. ("Parent") and Cinnamon Acquisition, Inc., a wholly owned subsidiary of Parent ("Purchaser"), on February 24, 2023, Purchaser completed a tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the "Merger"). At the effective time of the Merger, each issued and outstanding Share was cancelled in exchange for (i) $26.00 per Share in cash (the "Cash Amount"), plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per share, [continues to footnote (2)]

F2 · price: [continues from footnote (1)] in cash, upon the achievement of a specified milestone by December 31, 2033 (the Cash Amount plus one CVR, collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes. Pursuant to the terms of the Merger Agreement, the Shares were tendered and disposed of at the Offer Acceptance Time (as defined in the Merger Agreement) in exchange for the right to receive the Offer Price.

F4 · ownership.nature: Shares are held by 5AM Opportunities II, L.P. ("Opportunities II"). 5AM Opportunities II (GP), LLC ("Opportunities II GP") is the sole general partner of Opportunities II. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities II GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities II. Each of Opportunities II GP, Mr. Schwab and Dr. Parmar disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0001209191-23-013671 · doc4.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 0

F1 · shares: Pursuant to the Agreement and Plan of Merger (the "Merger Agreement"), dated as of January 8, 2023, by and among CinCor Pharma, Inc. (the "Issuer"), AstraZeneca Finance and Holdings Inc. ("Parent") and Cinnamon Acquisition, Inc., a wholly owned subsidiary of Parent ("Purchaser"), on February 24, 2023, Purchaser completed a tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the "Merger"). At the effective time of the Merger, each issued and outstanding Share was cancelled in exchange for (i) $26.00 per Share in cash (the "Cash Amount"), plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per share, [continues to footnote (2)]

F2 · shares: [continues from footnote (1)] in cash, upon the achievement of a specified milestone by December 31, 2033 (the Cash Amount plus one CVR, collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes. Pursuant to the terms of the Merger Agreement, the Shares were tendered and disposed of at the Offer Acceptance Time (as defined in the Merger Agreement) in exchange for the right to receive the Offer Price.

F1 · price: Pursuant to the Agreement and Plan of Merger (the "Merger Agreement"), dated as of January 8, 2023, by and among CinCor Pharma, Inc. (the "Issuer"), AstraZeneca Finance and Holdings Inc. ("Parent") and Cinnamon Acquisition, Inc., a wholly owned subsidiary of Parent ("Purchaser"), on February 24, 2023, Purchaser completed a tender offer for shares of common stock of the Issuer (each, a "Share") and thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the "Merger"). At the effective time of the Merger, each issued and outstanding Share was cancelled in exchange for (i) $26.00 per Share in cash (the "Cash Amount"), plus (ii) one contingent value right (each, a "CVR") per Share representing the right to receive a contingent payment of $10.00 per share, [continues to footnote (2)]

F2 · price: [continues from footnote (1)] in cash, upon the achievement of a specified milestone by December 31, 2033 (the Cash Amount plus one CVR, collectively, the "Offer Price"), in each case, without interest, subject to any applicable withholding taxes. Pursuant to the terms of the Merger Agreement, the Shares were tendered and disposed of at the Offer Acceptance Time (as defined in the Merger Agreement) in exchange for the right to receive the Offer Price.

F3 · ownership.nature: Shares are held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0000899243-23-001048 · doc4.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,344

Underlying: Common Stock · 10,344 shares

Expires 2033-01-03

F1 · derivative.exercise_date: The option vests as to the underlying shares of Common Stock in 12 equal installments, each on the last day of each month of calendar year 2023.

SEC source: 0001104659-22-124136 · tm2231851-3_4seq1.xml · derivative · entry 3

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 16,000 shares

Expires 2032-06-22

F5 · price: At the effective time of the merger (the "Effective Time"), pursuant to the Merger Agreement, each outstanding option to purchase Shares having an exercise price less than $12.50 per Share, whether or not vested, was cancelled and converted into the right to receive (x) an amount in cash, without interest and less any applicable tax withholdings, equal to the product of (A) the total number of Shares subject to such option immediately prior to the Effective Time multiplied by (B) the excess, if any, of the Cash Consideration over the applicable exercise price per Share under such option and (y) one CVR for each Share subject to such option immediately prior to the Effective Time (without regard to vesting).

F5 · derivative.exercise_date: At the effective time of the merger (the "Effective Time"), pursuant to the Merger Agreement, each outstanding option to purchase Shares having an exercise price less than $12.50 per Share, whether or not vested, was cancelled and converted into the right to receive (x) an amount in cash, without interest and less any applicable tax withholdings, equal to the product of (A) the total number of Shares subject to such option immediately prior to the Effective Time multiplied by (B) the excess, if any, of the Cash Consideration over the applicable exercise price per Share under such option and (y) one CVR for each Share subject to such option immediately prior to the Effective Time (without regard to vesting).

SEC source: 0001104659-22-124136 · tm2231851-3_4seq1.xml · nonDerivative · entry 2

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F1 · shares: Pursuant to the terms of that certain Agreement and Plan of Merger (the "Merger Agreement"), by and among the Issuer, Eli Lilly and Company ("Parent") and Kearny Acquisition Corporation ("Merger Sub"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer ("Shares") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest (the "Cash Consideration") and less any applicable tax withholding, plus [Continued on Note 2]

F2 · shares: [Continuation of Note 1] (ii) one non-tradable contingent value right ("CVR") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A.

F1 · price: Pursuant to the terms of that certain Agreement and Plan of Merger (the "Merger Agreement"), by and among the Issuer, Eli Lilly and Company ("Parent") and Kearny Acquisition Corporation ("Merger Sub"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer ("Shares") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest (the "Cash Consideration") and less any applicable tax withholding, plus [Continued on Note 2]

F2 · price: [Continuation of Note 1] (ii) one non-tradable contingent value right ("CVR") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A.

F4 · ownership.nature: Shares were held directly by 5AM Opportunities I, L.P. ("Opportunities I"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the general partner of Opportunities I and may be deemed to have sole investment and voting power over the Shares held by Opportunities I. The Reporting Person is a Managing Member of Opportunities GP and may be deemed to have shared voting and dispositive power over the Shares held by Opportunities I. Therefore, the Reporting Person may be deemed to have beneficially owned the Shares held by Opportunities I. The Reporting Person disclaims beneficial ownership over the Shares held by Opportunities I except to the extent of his pecuniary interest therein.

SEC source: 0001104659-22-124136 · tm2231851-3_4seq1.xml · nonDerivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F1 · shares: Pursuant to the terms of that certain Agreement and Plan of Merger (the "Merger Agreement"), by and among the Issuer, Eli Lilly and Company ("Parent") and Kearny Acquisition Corporation ("Merger Sub"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer ("Shares") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest (the "Cash Consideration") and less any applicable tax withholding, plus [Continued on Note 2]

F2 · shares: [Continuation of Note 1] (ii) one non-tradable contingent value right ("CVR") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A.

F1 · price: Pursuant to the terms of that certain Agreement and Plan of Merger (the "Merger Agreement"), by and among the Issuer, Eli Lilly and Company ("Parent") and Kearny Acquisition Corporation ("Merger Sub"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer ("Shares") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest (the "Cash Consideration") and less any applicable tax withholding, plus [Continued on Note 2]

F2 · price: [Continuation of Note 1] (ii) one non-tradable contingent value right ("CVR") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A.

F3 · ownership.nature: Shares were held directly by 5AM Ventures V, L.P. ("Ventures V"). 5AM Partners V, LLC ("Partners V") is the general partner of Ventures V and may be deemed to have sole investment and voting power over the Shares held by Ventures V. The Reporting Person is a Managing Member of Partners V and may be deemed to have shared voting and dispositive power over the Shares held by Ventures V. Therefore, the Reporting Person may be deemed to have beneficially owned the Shares held by Ventures V. The Reporting Person disclaims beneficial ownership over the Shares held by Ventures V except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-046494 · doc4.xml · nonDerivative · entry 2

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Opportunities II, L.P.

Disclosed balance after: 487,333

F2 · ownership.nature: Shares are held by 5AM Opportunities II, L.P. ("Opportunities II"). 5AM Opportunities II (GP), LLC ("Opportunities II GP") is the sole general partner of Opportunities II. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities II GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities II. Each of Opportunities II GP, Mr. Schwab and Dr. Parmar disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0001209191-22-046494 · doc4.xml · nonDerivative · entry 1

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

5AM Opportunities II (GP), LLC · CIK 0001873515 · 10% owner

5AM Opportunities II, L.P. · CIK 0001844401 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 3,953,990

F1 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0001104659-22-074826 · tm2219359-1_4seq1.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,000

Underlying: Common Stock · 16,000 shares

Expires 2032-06-22

F1 · derivative.exercise_date: This option was granted on June 23, 2022. The shares underlying the option will fully vest on the earlier of (i) June 23, 2023 and (ii) the date of the Issuer's 2023 annual meeting of stockholders.

SEC source: 0000899243-22-023063 · doc4.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,000

Underlying: Common Stock · 18,000 shares

Expires 2032-06-15

F1 · derivative.exercise_date: This option shall vest and become exercisable on the earlier of June 15, 2023 or the day immediately prior to the date of the Issuer's next annual meeting of stockholders occurring after the date of grant, in either case subject to the Reporting Person continuing in service on the Board as a Non-Employee Director through such vesting date.

SEC source: 0001209191-22-037516 · doc4.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,911

Underlying: Common Stock · 16,911 shares

Expires 2032-06-13

F1 · derivative.exercise_date: This option was granted to the Reporting Person pursuant to the Issuer's non-employee director compensation policy. The shares underlying the option vest and become exercisable on the earlier of (i) June 14, 2023 or (ii) the Issuer's next annual meeting of stockholders following the grant date, in each case, subject to the Reporting Person's continued service as a director through such date.

SEC source: 0001209191-22-034860 · doc4.xml · nonDerivative · entry 2

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 1,251,755

F2 · ownership.nature: These securities are held directly by 5AM Opportunities I, L.P. ("Opportunities I, L.P."). 5AM Opportunities I (GP), LLC ("Opportunities I (GP)") is the general partner of Opportunities I, L.P. Dr. Parmar is a managing member of Opportunities I (GP), and may be deemed to share voting and dispositive power over the securities held by Opportunities I, L.P. Dr. Parmar disclaims beneficial ownership of the securities held by Opportunities I, L.P. except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-034860 · doc4.xml · nonDerivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures V, L.P.

Disclosed balance after: 2,478,969

F1 · ownership.nature: These securities are held directly by 5AM Ventures V, L.P. ("Ventures V"). 5AM Partners V, LLC ("Partners V") is the sole general partner of Ventures V. Dr. Parmar is a managing member of Partners V and may be deemed to share voting and investment power over the securities held by Ventures V. Dr. Parmar disclaims beneficial ownership of the securities held by Ventures V except to the extent of his pecuniary interest therein.

SEC source: 0001104659-22-068502 · tm2217670-3_4seq1.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,918

Underlying: Common Stock · 11,918 shares

Expires 2032-06-02

F1 · derivative.exercise_date: The shares subject to this option shall vest and become exercisable on the earlier of (i) the one-year anniversary of June 2, 2022 (the "Vesting Start Date") or (ii) the Issuer's next annual meeting of stockholders.

SEC source: 0000899243-22-019827 · doc4.xml · derivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,440

Underlying: Common Stock · 13,440 shares

Expires 2032-05-24

F1 · derivative.exercise_date: The option was granted under the Company's 2021 Equity Incentive Plan. The option vests on the earlier of May 24, 2023 or the date of the Company's 2023 Annual Meeting of Stockholders.

SEC source: 0001209191-22-031969 · doc4.xml · nonDerivative · entry 2

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 1,302,084

F2 · ownership.nature: These securities are held directly by 5AM Opportunities I, L.P. ("Opportunities I, L.P."). 5AM Opportunities I (GP), LLC ("Opportunities I (GP)") is the general partner of Opportunities I, L.P. Dr. Parmar is a managing member of Opportunities I (GP), and may be deemed to share voting and dispositive power over the securities held by Opportunities I, L.P. Dr. Parmar disclaims beneficial ownership of the securities held by Opportunities I, L.P. except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-031969 · doc4.xml · nonDerivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures V, L.P.

Disclosed balance after: 2,578,640

F1 · ownership.nature: These securities are held directly by 5AM Ventures V, L.P. ("Ventures V"). 5AM Partners V, LLC ("Partners V") is the sole general partner of Ventures V. Dr. Parmar is a managing member of Partners V and may be deemed to share voting and investment power over the securities held by Ventures V. Dr. Parmar disclaims beneficial ownership of the securities held by Ventures V except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-008579 · doc4.xml · nonDerivative · entry 2

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · 5AM Opportunities I, L.P.

Disclosed balance after: 1,335,637

F2 · ownership.nature: These securities are held directly by 5AM Opportunities I, L.P. ("Opportunities I, L.P."). 5AM Opportunities I (GP), LLC ("Opportunities I (GP)") is the general partner of Opportunities I, L.P. Dr. Parmar is a managing member of Opportunities I (GP), and may be deemed to share voting and dispositive power over the securities held by Opportunities I, L.P. Dr. Parmar disclaims beneficial ownership of the securities held by Opportunities I, L.P. except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-008579 · doc4.xml · nonDerivative · entry 1

PARMAR KUSH · CIK 0001664281 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · 5AM Ventures V, L.P.

Disclosed balance after: 2,645,087

F1 · ownership.nature: These securities are held directly by 5AM Ventures V, L.P. ("Ventures V"). 5AM Partners V, LLC ("Partners V") is the sole general partner of Ventures V. Dr. Parmar is a managing member of Partners V and may be deemed to share voting and investment power over the securities held by Ventures V. Dr. Parmar disclaims beneficial ownership of the securities held by Ventures V except to the extent of his pecuniary interest therein.

SEC source: 0001209191-22-003205 · doc4.xml · derivative · entry 7

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Opportunities I, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 183,823 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F3 · ownership.nature: Shares are held by 5AM Opportunities I, L.P. ("Opportunities"). 5AM Opportunities I (GP), LLC ("Opportunities GP") is the sole general partner of Opportunities. Andrew J. Schwab and Dr. Kush Parmar are the managing members of Opportunities GP and may be deemed to have shared voting and investment power over the shares beneficially owned by Opportunities. Each of Opportunities GP, Mr. Schwab and Dr. Parmar disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0001209191-22-003205 · doc4.xml · derivative · entry 6

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 742,647 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.

SEC source: 0001209191-22-003205 · doc4.xml · derivative · entry 5

5AM Partners VI, LLC · CIK 0001829051 · 10% owner

5AM Ventures VI, L.P. · CIK 0001753037 · 10% owner

5AM Opportunities I (GP), LLC · CIK 0001790778 · 10% owner

5AM Opportunities I, L.P. · CIK 0001753000 · 10% owner

Schwab Andrew J. · CIK 0001598549 · 10% owner

PARMAR KUSH · CIK 0001664281 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By 5AM Ventures VI, L.P.

Disclosed balance after: 0

Underlying: Common Stock · 2,941,176 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F1 · derivative.exercise_date: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F1 · derivative.expiration_date: Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering (the "IPO") for no additional consideration, on a 3.4:1 basis, and had no expiration date.

F2 · ownership.nature: The shares are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the shares beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such shares except to the extent of its or his pecuniary interest therein.