ARVN

SEC source: 0001628280-26-045286 · wk-form4_1782336014.xml · nonDerivative · entry 1

Saik Andrew · CIK 0001616284 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 187,432

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on June 24, 2024, pursuant to a durable sale instruction. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-045785 · wk-form4_1782505325.xml · derivative · entry 3

Kennedy Edward Moore Jr. · CIK 0001753859 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,714

Underlying: Common Stock · 22,714 shares

Expires 2036-06-23

F2 · derivative.exercise_date: This option award was granted on June 24, 2026. The shares underlying the award shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045785 · wk-form4_1782505325.xml · nonDerivative · entry 1

Kennedy Edward Moore Jr. · CIK 0001753859 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,957

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 24, 2026 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045787 · wk-form4_1782505378.xml · derivative · entry 2

Norwalk Leslie V · CIK 0001533568 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,714

Underlying: Common Stock · 22,714 shares

Expires 2036-06-23

F2 · derivative.exercise_date: This option award was granted on June 24, 2026. The shares underlying the award shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045787 · wk-form4_1782505378.xml · nonDerivative · entry 1

Norwalk Leslie V · CIK 0001533568 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,572

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 24, 2026 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045783 · wk-form4_1782505294.xml · derivative · entry 2

Cunningham Everett · CIK 0001564777 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,714

Underlying: Common Stock · 22,714 shares

Expires 2036-06-23

F2 · derivative.exercise_date: This option award was granted on June 24, 2026. The shares underlying the award shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045783 · wk-form4_1782505294.xml · nonDerivative · entry 1

Cunningham Everett · CIK 0001564777 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,572

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 24, 2026 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045781 · wk-form4_1782505262.xml · derivative · entry 2

Bain Linda · CIK 0001578407 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,714

Underlying: Common Stock · 22,714 shares

Expires 2036-06-23

F2 · derivative.exercise_date: This option award was granted on June 24, 2026. The shares underlying the award shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045781 · wk-form4_1782505262.xml · nonDerivative · entry 1

Bain Linda · CIK 0001578407 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,572

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 24, 2026 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045788 · wk-form4_1782505401.xml · derivative · entry 2

Smaldone Alsup Laurie · CIK 0001589602 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,714

Underlying: Common Stock · 22,714 shares

Expires 2036-06-23

F2 · derivative.exercise_date: This option award was granted on June 24, 2026. The shares underlying the award shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045788 · wk-form4_1782505401.xml · nonDerivative · entry 1

Smaldone Alsup Laurie · CIK 0001589602 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,572

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 24, 2026 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045786 · wk-form4_1782505358.xml · derivative · entry 2

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,714

Underlying: Common Stock · 22,714 shares

Expires 2036-06-23

F2 · derivative.exercise_date: This option award was granted on June 24, 2026. The shares underlying the award shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-045786 · wk-form4_1782505358.xml · nonDerivative · entry 1

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 111,548

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 24, 2026 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of (i) June 24, 2027 or (ii) immediately prior to the first annual meeting of stockholders occurring after the date of grant, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001628280-26-044270 · wk-form4_1781813208.xml · nonDerivative · entry 1

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 180,390

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on June 17, 2024 pursuant to a durable sale instruction. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-037728 · wk-form4_1779480918.xml · nonDerivative · entry 1

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 285,009

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on May 21, 2024. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-034608 · wk-form4_1778703409.xml · nonDerivative · entry 1

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 182,966

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on May 9, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-034602 · wk-form4_1778703312.xml · nonDerivative · entry 1

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 287,218

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on May 9, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-034612 · wk-form4_1778703462.xml · nonDerivative · entry 1

Loomis David K · CIK 0001959410 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,193

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on May 9, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-034606 · wk-form4_1778703361.xml · nonDerivative · entry 1

Berkowitz Noah · CIK 0001369900 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 191,395

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on May 9, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-034615 · wk-form4_1778703501.xml · nonDerivative · entry 1

Saik Andrew · CIK 0001616284 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 193,128

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on May 9, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-019950 · wk-form4_1773964912.xml · nonDerivative · entry 1

Berkowitz Noah · CIK 0001369900 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 202,503

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on March 18, 2024. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-016003 · wk-form4_1773086718.xml · nonDerivative · entry 1

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,021

F1 · price: The purchase price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $13.364 to $13.45, inclusive. The reporting person undertakes to provide to Arvinas, Inc., any security holder of Arvinas, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote.

SEC source: 0001628280-26-013527 · wk-form4_1772503035.xml · nonDerivative · entry 3

Houston John G · CIK 0001753537 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,122,183

F3 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-quarter of the reporting person's restricted stock units (RSUs) granted on February 13, 2025 when the reporting person was serving as President and CEO. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-013527 · wk-form4_1772503035.xml · nonDerivative · entry 2

Houston John G · CIK 0001753537 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,133,970

F2 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on February 23, 2024 when the reporting person was serving as President and CEO. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-013527 · wk-form4_1772503035.xml · nonDerivative · entry 1

Houston John G · CIK 0001753537 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,152,792

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-quarter of the reporting person's restricted stock units (RSUs) granted on February 22, 2023 when the reporting person was serving as President and CEO. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-013535 · wk-form4_1772503231.xml · derivative · entry 2

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,000

Underlying: Common Stock · 67,000 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option was granted by the Issuer on February 26, 2026, pursuant to the Plan. The shares underlying the option vest over four years: one-quarter of the shares underlying the award will vest on February 26, 2027, with the remainder of the shares vesting in equal monthly installments following February 26, 2027 through February 26, 2030, subject to the reporting person's continued service with the Issuer on each vesting date.

SEC source: 0001628280-26-013535 · wk-form4_1772503231.xml · nonDerivative · entry 1

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 192,623

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 26, 2027, February 26, 2028, February 26, 2029 and February 26, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date.

SEC source: 0001628280-26-013529 · wk-form4_1772503084.xml · derivative · entry 2

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 218,691

Underlying: Common Stock · 218,691 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option was granted by the Issuer on February 26, 2026, pursuant to the Plan. The shares underlying the option vest over four years: one-quarter of the shares underlying the award will vest on February 12, 2027, with the remainder of the shares vesting in equal monthly installments following February 12, 2027 through February 12, 2030, subject to the reporting person's continued service with the Issuer on each vesting date.

SEC source: 0001628280-26-013529 · wk-form4_1772503084.xml · nonDerivative · entry 1

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 297,487

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 12, 2027, February 12, 2028, February 12, 2029 and February 12, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date.

SEC source: 0001628280-26-013537 · wk-form4_1772503268.xml · derivative · entry 2

Loomis David K · CIK 0001959410 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,504

Underlying: Common Stock · 18,504 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option was granted by the Issuer on February 26, 2026, pursuant to the Plan. The shares underlying the option vest over four years: one-quarter of the shares underlying the award will vest on February 26, 2027, with the remainder of the shares vesting in equal monthly installments following February 26, 2027 through February 26, 2030, subject to the reporting person's continued service with the Issuer on each vesting date.

SEC source: 0001628280-26-013537 · wk-form4_1772503268.xml · nonDerivative · entry 1

Loomis David K · CIK 0001959410 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,112

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 26, 2027, February 26, 2028, February 26, 2029 and February 26, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date.

SEC source: 0001628280-26-013533 · wk-form4_1772503183.xml · derivative · entry 2

Berkowitz Noah · CIK 0001369900 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,000

Underlying: Common Stock · 67,000 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option was granted by the Issuer on February 26, 2026, pursuant to the Plan. The shares underlying the option vest over four years: one-quarter of the shares underlying the award will vest on February 26, 2027, with the remainder of the shares vesting in equal monthly installments following February 26, 2027 through February 26, 2030, subject to the reporting person's continued service with the Issuer on each vesting date.

SEC source: 0001628280-26-013533 · wk-form4_1772503183.xml · nonDerivative · entry 1

Berkowitz Noah · CIK 0001369900 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 208,938

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 26, 2027, February 26, 2028, February 26, 2029 and February 26, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date.

SEC source: 0001628280-26-013531 · wk-form4_1772503133.xml · derivative · entry 2

Saik Andrew · CIK 0001616284 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,000

Underlying: Common Stock · 67,000 shares

Expires 2036-02-25

F2 · derivative.exercise_date: The option was granted by the Issuer on February 26, 2026, pursuant to the Plan. The shares underlying the option vest over four years: one-quarter of the shares underlying the award will vest on February 26, 2027, with the remainder of the shares vesting in equal monthly installments following February 26, 2027 through February 26, 2030, subject to the reporting person's continued service with the Issuer on each vesting date.

SEC source: 0001628280-26-013531 · wk-form4_1772503133.xml · nonDerivative · entry 1

Saik Andrew · CIK 0001616284 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 204,267

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 26, 2027, February 26, 2028, February 26, 2029 and February 26, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date.

SEC source: 0001628280-26-017385 · wk-form4a_1773351633.xml · nonDerivative · entry 1

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 296,875

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 12, 2027, February 12, 2028, February 12, 2029 and February 12, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date.

F2 · shares: This amendment is being filed to correct an inadvertent clerical error in reporting the number of RSUs awarded on February 26, 2026. The correct number of RSUs awarded was 147,179, not 147,791, as was originally reported on the Form 4 filed on March 2, 2026. Column 5, the amount of securities beneficially owned following reported transaction(s), has also been corrected accordingly.

SEC source: 0001628280-26-011786 · wk-form4_1772057348.xml · nonDerivative · entry 2

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 147,623

F2 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on February 23, 2024. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-011786 · wk-form4_1772057348.xml · nonDerivative · entry 1

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 150,194

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-quarter of the reporting person's restricted stock units (RSUs) granted on February 22, 2023. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-011785 · wk-form4_1772057324.xml · nonDerivative · entry 2

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 149,696

F2 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on February 23, 2024. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-011785 · wk-form4_1772057324.xml · nonDerivative · entry 1

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,444

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-quarter of the reporting person's restricted stock units (RSUs) granted on February 22, 2023. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-011787 · wk-form4_1772057370.xml · nonDerivative · entry 1

Loomis David K · CIK 0001959410 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,692

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of one-half of the reporting person's restricted stock units (RSUs) granted on February 23, 2024. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-009303 · wk-form4_1771456394.xml · nonDerivative · entry 1

Cacace Angela M · CIK 0002026306 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 151,232

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on February 13, 2025. The sale does not represent a discretionary trade.

F2 · balance_after: Includes an aggregate of 1,576 shares of common stock of the Issuer previously purchased under and in accordance with the 2018 Employee Stock Purchase Plan of the issuer in transactions exempt under Rule 16b-3.

SEC source: 0001628280-26-009312 · wk-form4_1771456614.xml · nonDerivative · entry 1

Teel Randy · CIK 0002015998 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 154,482

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on February 13, 2026. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-009298 · wk-form4_1771456271.xml · nonDerivative · entry 1

Loomis David K · CIK 0001959410 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,800

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on February 13, 2025. The sale does not represent a discretionary trade.

F2 · balance_after: Includes an aggregate of 119 shares of common stock of the issuer previously purchased under and in accordance with the 2018 Employee Stock Purchase Plan of the issuer in transactions exempt under Rule 16b-3.

SEC source: 0001628280-26-009300 · wk-form4_1771456332.xml · nonDerivative · entry 1

Berkowitz Noah · CIK 0001369900 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 163,938

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on February 13, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-26-009306 · wk-form4_1771456485.xml · nonDerivative · entry 1

Saik Andrew · CIK 0001616284 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 159,267

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on February 13, 2025. The sale does not represent a discretionary trade.

SEC source: 0001628280-25-050669 · wk-form4_1762550421.xml · nonDerivative · entry 1

Loomis David K · CIK 0001959410 · Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,697

F1 · shares: This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on December 13, 2022.

F2 · balance_after: Includes an aggregate of 1,239 shares of common stock of the issuer previously purchased under and in accordance with the 2018 Employee Stock Purchase Plan of the issuer in transactions exempt under Rule 16b-3.

SEC source: 0001628280-25-042536 · wk-form4_1758719774.xml · nonDerivative · entry 1

Morrison Briggs · CIK 0001654430 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 76,021

F1 · price: The purchase price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.50 to $7.65, inclusive. The reporting person undertakes to provide to Arvinas, Inc., any security holder of Arvinas, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote.

SEC source: 0001655759-25-000116 · wk-form4_1751072995.xml · derivative · entry 3

Kennedy Edward Moore Jr. · CIK 0001753859 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,105

Underlying: Common Stock · 23,105 shares

Expires 2035-06-24

F2 · derivative.exercise_date: This option award was granted on June 25, 2025. The shares underlying the award shall vest in full on the earlier of June 25, 2026 or the first meeting of the board of directors of the Issuer held after the following annual meeting of stockholders, subject to the reporting person's continued service with the Issuer on the vesting date.

SEC source: 0001655759-25-000116 · wk-form4_1751072995.xml · nonDerivative · entry 1

Kennedy Edward Moore Jr. · CIK 0001753859 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,430

F1 · shares: The restricted stock units (each, an "RSU") were granted by the Issuer on June 25, 2025 and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs shall vest in full on the earlier of June 25, 2026 or the first meeting of the board of directors of the Issuer held after the following annual meeting of stockholders, subject to the reporting person's continued service with the Issuer on the vesting date.