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person · Reporting owner

Talasaz AmirAli

Disclosed activity across 1 company

Tapewire entity
20365
SEC CIK
0001753159

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Guardant Health, Inc.GH · Entity 3238Director · Co-Chief Executive OfficerSeptember 30, 2026October 03, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Guardant Health, Inc.

Report date September 30, 2026 · Filed October 03, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,827,168 Reported balance After 2026-09-30 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 1 · 2026-09-30 · Exercise / conversion · Acquired 2,817 · Balance 1,827,168

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,825,740 Reported balance After 2026-09-30 transaction · row 2 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 2 · 2026-09-30 · Tax withholding · Disposed 1,428 · Balance 1,825,740

F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,849,737 Reported balance After 2026-10-01 transaction · row 3 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 3 · 2026-10-01 · Exercise / conversion · Acquired 23,997 · Balance 1,849,737

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,859,453 Reported balance After 2026-10-01 transaction · row 4 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 4 · 2026-10-01 · Exercise / conversion · Acquired 9,716 · Balance 1,859,453

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,842,366 Reported balance After 2026-10-01 transaction · row 5 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 5 · 2026-10-01 · Tax withholding · Disposed 17,087 · Balance 1,842,366

F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct2,817 Reported balance After 2026-09-30 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-09-30 · Exercise / conversion · Disposed 2,817 · Balance 2,817

F2: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3: Not applicable for Restricted Stock Units.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct23,998 Reported balance After 2026-10-01 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-10-01 · Exercise / conversion · Disposed 23,997 · Balance 23,998

F4: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3: Not applicable for Restricted Stock Units.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct48,580 Reported balance After 2026-10-01 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2026-10-01 · Exercise / conversion · Disposed 9,716 · Balance 48,580

F5: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3: Not applicable for Restricted Stock Units.

Filing footnotes · ownership attribution and instrument terms

F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

F2: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3: Not applicable for Restricted Stock Units.

F4: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F5: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
October 01, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 9,716 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · derivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 48,580

Underlying: Common Stock · 9,716 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
October 01, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 23,997 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · derivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,998

Underlying: Common Stock · 23,997 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
October 01, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 17,087 $174.75 $2,985,953.25
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,842,366

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
October 01, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 9,716 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,859,453

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 01, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 23,997 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,849,737

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 30, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 2,817 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · derivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,817

Underlying: Common Stock · 2,817 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
September 30, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 1,428 $178.36 $254,698.08
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,825,740

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
September 30, 2026 Filed Oct 3, 2026 00:58 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 2,817 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000022 · wk-form4_1790974735.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,827,168

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
August 21, 2026 Filed Aug 24, 2026 21:21 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 7,589 $170.29 $1,292,301.97
Disclosure

SEC source: 0001753159-26-000020 · wk-form4_1787606490.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by the Talasaz Family Foundation

Disclosed balance after: 37,500

F3 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $169.88 to $170.50. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
August 21, 2026 Filed Aug 24, 2026 21:21 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 20,888 $169.16 $3,533,451.68
Disclosure

SEC source: 0001753159-26-000020 · wk-form4_1787606490.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by the Talasaz Family Foundation

Disclosed balance after: 45,089

F2 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $168.87 to $169.73. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
August 21, 2026 Filed Aug 24, 2026 21:21 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 9,023 $168.20 $1,517,630.70
Disclosure

SEC source: 0001753159-26-000020 · wk-form4_1787606490.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by the Talasaz Family Foundation

Disclosed balance after: 65,977

F1 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $167.81 to $168.60. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
August 10, 2026 Filed Aug 12, 2026 22:20 UTC Guardant Health, Inc. GH · Entity 3238 GiftCommon Stock 75,000 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000018 · wk-form4_1786573235.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by the Talasaz Family Foundation

Disclosed balance after: 75,000

F1 · shares: Reflects changes in form of ownership from Talasaz and Eskandari 2017 Family Trust due to the gift of shares to The Talasaz Family Foundation.

Read SEC document
August 10, 2026 Filed Aug 12, 2026 22:20 UTC Guardant Health, Inc. GH · Entity 3238 GiftCommon Stock 75,000 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000018 · wk-form4_1786573235.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,824,351

F1 · shares: Reflects changes in form of ownership from Talasaz and Eskandari 2017 Family Trust due to the gift of shares to The Talasaz Family Foundation.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 9,715 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · derivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,296

Underlying: Common Stock · 9,715 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 23,997 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · derivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,995

Underlying: Common Stock · 23,997 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 17,086 $170.77 $2,917,776.22
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,899,351

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 9,715 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,916,437

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 01, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 23,997 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,906,722

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 30, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 2,817 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · derivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,634

Underlying: Common Stock · 2,817 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
June 30, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 1,428 $150.03 $214,242.84
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,882,725

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
June 30, 2026 Filed Jul 2, 2026 22:09 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 2,817 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000016 · wk-form4_1783030139.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,884,153

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 29, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionStock Option (Right to Buy) · Derivative 143,028 $0.00 Strike: $4.18 $0.00
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · derivative · entry 10

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,997

Underlying: Common Stock · 143,028 shares

Expires 2027-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The stock option vested in equal monthly installments over 48 months commencing on April 23, 2017.

Read SEC document
June 29, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 40 $153.00 $6,120.00
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,881,336

Read SEC document
June 29, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 46,663 $152.20 $7,102,318.58
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,881,376

F4 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $152.00 to $152.68. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
June 29, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 70,513 $151.47 $10,680,315.01
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,928,039

F3 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $151.00 to $151.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
June 29, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 25,812 $150.53 $3,885,433.90
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,998,552

F1 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $150.00 to $150.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
June 29, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 143,028 $4.18 $597,857.04
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,024,364

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 26, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionStock Option (Right to Buy) · Derivative 111,804 $0.00 Strike: $4.18 $0.00
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · derivative · entry 9

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 172,025

Underlying: Common Stock · 111,804 shares

Expires 2027-07-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The stock option vested in equal monthly installments over 48 months commencing on April 23, 2017.

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June 26, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 52,935 $151.16 $8,001,628.13
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,881,336

F2 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $151.00 to $151.79. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

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June 26, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 64,037 $150.49 $9,636,838.48
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,934,271

F1 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $150.00 to $150.99. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

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June 26, 2026 Filed Jun 30, 2026 21:13 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 111,804 $4.18 $467,340.72
Disclosure

SEC source: 0001753159-26-000014 · wk-form4_1782854022.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,998,308

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 26,352 $112.76 $2,971,430.44
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 12

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,886,504

F11 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $112.74 to $112.93. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

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May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 37,900 $112.02 $4,245,546.63
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 11

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,912,856

F10 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $111.73 to $112.70. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

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May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 37,163 $111.14 $4,130,470.49
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 10

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,950,756

F9 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $110.72 to $111.71. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 28,908 $110.10 $3,182,652.28
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 9

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 1,987,919

F8 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $109.66 to $110.58. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

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May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 9,852 $108.97 $1,073,546.82
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,016,827

F7 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $108.59 to $109.56. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

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May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 33,069 $108.11 $3,574,960.62
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,026,679

F6 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $107.59 to $108.57. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 21,171 $106.99 $2,265,125.51
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,059,748

F5 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $106.57 to $107.52. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 1,200 $105.88 $127,050.00
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,080,919

F4 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $105.49 to $106.42. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 11,919 $105.01 $1,251,589.16
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,082,119

F3 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $104.400 to $105.39. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 1,366 $103.82 $141,815.11
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,094,038

F2 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $103.40 to $104.26. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 900 $102.57 $92,313.00
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,095,404

F1 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $102.29 to $103.06. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
May 20, 2026 Filed May 22, 2026 20:57 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 200 $100.95 $20,190.00
Disclosure

SEC source: 0001753159-26-000012 · wk-form4_1779483475.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,096,304

Read SEC document
May 12, 2026 Filed May 13, 2026 21:32 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 50,000 $100.32 $5,016,000.00
Disclosure

SEC source: 0001753159-26-000010 · wk-form4_1778707917.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,096,504

F1 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $100.30 to $100.34. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
April 01, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 9,716 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · derivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,011

Underlying: Common Stock · 9,716 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
April 01, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 23,997 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · derivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,992

Underlying: Common Stock · 23,997 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
April 01, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 17,087 $91.15 $1,557,480.05
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,146,504

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

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April 01, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 9,716 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,163,591

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 01, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 23,997 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,153,875

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 31, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 2,817 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · derivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,451

Underlying: Common Stock · 2,817 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter: March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.