TapewireFind a company

person · Reporting owner

Talasaz AmirAli

Disclosed activity across 1 company

Tapewire entity
20365
SEC CIK
0001753159

Export transaction history ↓

Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
Guardant Health, Inc.GH · Entity 3238Director · Co-Chief Executive OfficerSeptember 30, 2026October 03, 2026

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

Guardant Health, Inc.

Report date September 30, 2026 · Filed October 03, 2026

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,827,168 Reported balance After 2026-09-30 transaction · row 1 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 1 · 2026-09-30 · Exercise / conversion · Acquired 2,817 · Balance 1,827,168

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,825,740 Reported balance After 2026-09-30 transaction · row 2 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 2 · 2026-09-30 · Tax withholding · Disposed 1,428 · Balance 1,825,740

F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,849,737 Reported balance After 2026-10-01 transaction · row 3 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 3 · 2026-10-01 · Exercise / conversion · Acquired 23,997 · Balance 1,849,737

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,859,453 Reported balance After 2026-10-01 transaction · row 4 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 4 · 2026-10-01 · Exercise / conversion · Acquired 9,716 · Balance 1,859,453

Common StockSEC Table I · non-derivativeIndirectShares held by Talasaz and Eskandari 2017 Family Trust1,842,366 Reported balance After 2026-10-01 transaction · row 5 Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source row

Row 5 · 2026-10-01 · Tax withholding · Disposed 17,087 · Balance 1,842,366

F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct2,817 Reported balance After 2026-09-30 transaction · row 6 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 6 · 2026-09-30 · Exercise / conversion · Disposed 2,817 · Balance 2,817

F2: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3: Not applicable for Restricted Stock Units.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct23,998 Reported balance After 2026-10-01 transaction · row 7 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 7 · 2026-10-01 · Exercise / conversion · Disposed 23,997 · Balance 23,998

F4: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3: Not applicable for Restricted Stock Units.

Restricted Stock UnitsSEC Table II · derivative / convertible security · Conversion / exercise price $0.00Direct48,580 Reported balance After 2026-10-01 transaction · row 8 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 8 · 2026-10-01 · Exercise / conversion · Disposed 9,716 · Balance 48,580

F5: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3: Not applicable for Restricted Stock Units.

Filing footnotes · ownership attribution and instrument terms

F1: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

F2: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F3: Not applicable for Restricted Stock Units.

F4: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F5: This represents a restricted stock unit award granted on March 12, 2025 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2026 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

Transaction history

JSON API
Reset

Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 31, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 1,428 $92.37 $131,904.36
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,129,878

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
March 31, 2026 Filed Apr 2, 2026 21:19 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 2,817 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000008 · wk-form4_1775164793.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,131,306

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 GrantRestricted Stock Units · Derivative 101,409 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · derivative · entry 10

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 101,409

Underlying: Common Stock · 101,409 shares

Expires not disclosed

F6 · derivative.exercise_date: This represents a restricted stock unit award granted on March 17, 2026 that vests over a three-year period. 33% of the shares subject to such award vests on January 1, 2027 and the remaining 67% of the shares vest in equal quarterly installments over the remaining two-year period thereafter.

F4 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 GrantRestricted Stock Units · Derivative 11,268 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · derivative · entry 9

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,268

Underlying: Common Stock · 11,268 shares

Expires not disclosed

F5 · derivative.exercise_date: This represents a restricted stock unit award granted on March 17, 2026 that vests in four equal installments on the last day of each calendar quarter, March 31, 2026, June 30, 2026, September 30, 2026, and December 31, 2026.

F4 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
March 13, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionPerformance-Based Restricted Stock Units · Derivative 26,961 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · derivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 26,961 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
March 13, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 13,664 $85.49 $1,168,135.36
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · nonDerivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,128,489

F2 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
March 13, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 26,961 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,142,153

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 01, 2026 Filed Jan 5, 2026 22:56 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 23,997 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000002 · wk-form4_1767653791.xml · derivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 95,989

Underlying: Common Stock · 23,997 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three-year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
January 01, 2026 Filed Jan 5, 2026 22:56 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 10,788 $102.14 $1,101,886.32
Disclosure

SEC source: 0001753159-26-000002 · wk-form4_1767653791.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,013,457

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
January 01, 2026 Filed Jan 5, 2026 22:56 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 23,997 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000002 · wk-form4_1767653791.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,024,245

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 01, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 38,283 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · derivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,727

Underlying: Common Stock · 38,283 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vested with respect to 33% of the shares on January 1, 2026 and the remaining 67% of the shares vest in equal quarterly installments over the remaining two-year period thereafter.

F4 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
January 01, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 19,402 $102.14 $1,981,720.28
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,115,192

F2 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
January 01, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 38,283 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,134,594

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
January 01, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 13,209 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,096,311

F1 · shares: Reflects changes in form of ownership from direct to indirect due to transfer of shares to Talasaz and Eskandari 2017 Family Trust.

Read SEC document
January 01, 2026 Filed Mar 18, 2026 01:57 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 13,209 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000006 · wk-form4_1773799065.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

F1 · shares: Reflects changes in form of ownership from direct to indirect due to transfer of shares to Talasaz and Eskandari 2017 Family Trust.

Read SEC document
December 31, 2025 Filed Jan 5, 2026 22:56 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 4,815 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000002 · wk-form4_1767653791.xml · derivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,815 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vests in four equal installments on the last day of each calendar quarter, March 31, 2025, June 30, 2025, September 30, 2025, and December 31, 2025.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
December 31, 2025 Filed Jan 5, 2026 22:56 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 2,441 $102.14 $249,323.74
Disclosure

SEC source: 0001753159-26-000002 · wk-form4_1767653791.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,000,248

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
December 31, 2025 Filed Jan 5, 2026 22:56 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 4,815 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000002 · wk-form4_1767653791.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,002,689

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
December 31, 2025 Filed Jan 22, 2026 22:44 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 82,854 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000004 · wk-form5_1769121839.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,083,102

F2 · shares: Reflects changes in form of ownership from Talasaz Investments LP due to the transfer of shares to Talasaz and Eskandari 2017 Family Trust.

Read SEC document
December 31, 2025 Filed Jan 22, 2026 22:44 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 2,000,248 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000004 · wk-form5_1769121839.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz and Eskandari 2017 Family Trust

Disclosed balance after: 2,000,248

F1 · shares: Reflects changes in form of ownership from direct to indirect due to transfer of shares to Talasaz and Eskandari 2017 Family Trust.

Read SEC document
December 31, 2025 Filed Jan 22, 2026 22:44 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 82,854 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000004 · wk-form5_1769121839.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz Investments, L.P.

Disclosed balance after: 0

F2 · shares: Reflects changes in form of ownership from Talasaz Investments LP due to the transfer of shares to Talasaz and Eskandari 2017 Family Trust.

Read SEC document
December 31, 2025 Filed Jan 22, 2026 22:44 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 2,000,248 $0.00 $0.00
Disclosure

SEC source: 0001753159-26-000004 · wk-form5_1769121839.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,209

F1 · shares: Reflects changes in form of ownership from direct to indirect due to transfer of shares to Talasaz and Eskandari 2017 Family Trust.

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 4,240 $106.00 $449,440.00
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 9

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 168,223

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 30,760 $105.34 $3,240,172.27
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 172,463

F3 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $105.00 to $105.81. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 15,000 $104.21 $1,563,124.50
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 203,223

F2 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $104.00 to $104.75. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 4,240 $106.00 $449,440.00
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 168,223

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 30,760 $105.34 $3,240,172.27
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 172,463

F3 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $105.00 to $105.81. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 15,000 $104.21 $1,563,124.50
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 203,223

F2 · price: Represents the weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $104.00 to $104.75. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 193,973 $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Maryam Eskandari 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 218,223

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 193,973 $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by AmirAli Talasaz 2018 Children's Remainder Trust, Dated 9/25/2018

Disclosed balance after: 218,223

F1 · shares: Reflects changes in form of ownership from Talasaz Investments LP due to the transfer of shares to The AmirAli Talasaz 2018 Children's Remainder Trust dated 9/25/2018, and Maryam Eskandari 2018 Children's Remainder Trust, dated 9/25/2018.

Read SEC document
December 08, 2025 Filed Dec 11, 2025 02:33 UTC Guardant Health, Inc. GH · Entity 3238 OtherCommon Stock 387,946 $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000006 · wk-form4_1765420401.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Indirect · Shares held by Talasaz Investments, L.P.

Disclosed balance after: 82,854

F1 · shares: Reflects changes in form of ownership from Talasaz Investments LP due to the transfer of shares to The AmirAli Talasaz 2018 Children's Remainder Trust dated 9/25/2018, and Maryam Eskandari 2018 Children's Remainder Trust, dated 9/25/2018.

Read SEC document
October 01, 2025 Filed Oct 3, 2025 00:03 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 23,997 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000004 · wk-form4_1759449830.xml · derivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,986

Underlying: Common Stock · 23,997 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: This represents a restricted stock unit award granted on March 18, 2024 that vests over a three year period. 33% of the shares subject to such award vested on January 1, 2025 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two year period.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
October 01, 2025 Filed Oct 3, 2025 00:03 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 12,162 $62.65 $761,949.30
Disclosure

SEC source: 0001753159-25-000004 · wk-form4_1759449830.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,997,874

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
October 01, 2025 Filed Oct 3, 2025 00:03 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 23,997 $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000004 · wk-form4_1759449830.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,010,036

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
September 30, 2025 Filed Oct 3, 2025 00:03 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 4,814 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000004 · wk-form4_1759449830.xml · derivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,815

Underlying: Common Stock · 4,814 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vests in four equal installments on the last day of each calendar quarter, March 31, 2025, June 30, 2025, September 30, 2025, and December 31, 2025.

F3 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
September 30, 2025 Filed Oct 3, 2025 00:03 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 2,440 $62.48 $152,451.20
Disclosure

SEC source: 0001753159-25-000004 · wk-form4_1759449830.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,986,039

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
September 30, 2025 Filed Oct 3, 2025 00:03 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 4,814 $0.00 $0.00
Disclosure

SEC source: 0001753159-25-000004 · wk-form4_1759449830.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,988,479

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 23,997 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · derivative · entry 8

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,983

Underlying: Common Stock · 23,997 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: This restricted stock unit award vested with respect to 1/3 of the shares on January 1, 2025. The remaining shares vest quarterly for the remaining twenty-four months.

F6 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 12,162 $50.71 $616,735.02
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · nonDerivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,983,665

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 23,997 $0.00 $0.00
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · nonDerivative · entry 5

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,995,827

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 27,932 $51.40 $1,435,836.08
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · nonDerivative · entry 4

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,971,830

F2 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $51.08 to $51.94 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
July 01, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 72,068 $50.67 $3,651,793.66
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,999,762

F2 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.08 to $51.07 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 30, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionRestricted Stock Units · Derivative 4,815 $0.00 Strike: $0.00 $0.00
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · derivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 9,629

Underlying: Common Stock · 4,815 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: This represents a restricted stock unit award granted on March 12, 2025 that vests in four equal installments on the last day of each calendar quarter, March 31, 2025, June 30, 2025, September 30, 2025, and December 31, 2025.

F6 · derivative.expiration_date: Not applicable for Restricted Stock Units.

Read SEC document
June 30, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 Tax withholdingCommon Stock 2,441 $52.04 $127,029.64
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,071,830

F1 · shares: These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

Read SEC document
June 30, 2025 Filed Jul 3, 2025 01:18 UTC Guardant Health, Inc. GH · Entity 3238 Exercise / conversionCommon Stock 4,815 $0.00 $0.00
Disclosure

SEC source: 0001576280-25-000213 · wk-form4_1751505523.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,074,271

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 09, 2025 Filed Jun 10, 2025 01:45 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 77,853 $50.09 $3,899,937.04
Disclosure

SEC source: 0001576280-25-000169 · wk-form4_1749519929.xml · nonDerivative · entry 3

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,069,456

F1 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.41 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 06, 2025 Filed Jun 10, 2025 01:45 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 39,751 $50.07 $1,990,420.02
Disclosure

SEC source: 0001576280-25-000169 · wk-form4_1749519929.xml · nonDerivative · entry 2

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,147,309

F1 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.25 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
June 05, 2025 Filed Jun 10, 2025 01:45 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 1,680 $50.00 $84,006.89
Disclosure

SEC source: 0001576280-25-000169 · wk-form4_1749519929.xml · nonDerivative · entry 1

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,187,060

F1 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F2 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.04 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
May 02, 2025 Filed May 6, 2025 01:02 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 13,932 $50.47 $703,150.83
Disclosure

SEC source: 0001576280-25-000141 · wk-form4_1746493315.xml · nonDerivative · entry 7

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,188,740

F1 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F8 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $50.00 to $50.84 per shares, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
May 01, 2025 Filed May 6, 2025 01:02 UTC Guardant Health, Inc. GH · Entity 3238 SaleCommon Stock 354 $52.57 $18,610.81
Disclosure

SEC source: 0001576280-25-000141 · wk-form4_1746493315.xml · nonDerivative · entry 6

Talasaz AmirAli · CIK 0001753159 · Director · Co-Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,202,672

F1 · shares: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 17, 2024.

F7 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $52.46 to $52.75 per shares, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.