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BRIMBLECOMBE ROGER W

Disclosed activity across 1 company

Tapewire entity
16995
SEC CIK
0001197034

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Reported relationships

Latest disclosed role at each company.

CompanyLast reported asReport datePublished
VERTEX PHARMACEUTICALS INC / MAVRTX · Entity 2875DirectorMarch 15, 2010March 16, 2010

Disclosed balances

About these balances

Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.

VERTEX PHARMACEUTICALS INC / MA

Report date March 15, 2010 · Filed March 16, 2010

Security / awardOwnership accountDisclosed shares / unitsDisclosure context
Common StockSEC Table I · non-derivativeDirect0 Ending reported balance After 2010-03-15 transaction · row 2
2 source rows · reconciled sequence

Row 1 · 2010-03-15 · Exercise / conversion · Acquired 10,000 · Balance 10,000

Row 2 · 2010-03-15 · Sale · Disposed 10,000 · Balance 0

F1: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $43.10 (range $42.80 to $43.52).

F3: Dr. Brimblecombe undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Stock OptionSEC Table II · derivative / convertible security · Conversion / exercise price $38.44 · Expires 2010-05-31Direct0 Reported balance After 2010-03-15 transaction · row 3 Instrument identity requires review; Table II rows are not merged.
1 source row

Row 3 · 2010-03-15 · Exercise / conversion · Disposed 10,000 · Balance 0

F4: Right to buy under under 1996 Stock and Option Plan, fully vested on grant date, 6/1/2000.

Filing footnotes · ownership attribution and instrument terms

F1: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

F2: Open market sales reported on this line occurred at a weighted average price of $43.10 (range $42.80 to $43.52).

F3: Dr. Brimblecombe undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

F4: Right to buy under under 1996 Stock and Option Plan, fully vested on grant date, 6/1/2000.

Transaction history

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateCompanyActivity / securityShares / unitsReported priceReported valueDetails
March 15, 2010 Filed Mar 16, 2010 20:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionStock Option · Derivative 10,000 $0.00 Strike: $38.44 $0.00
Disclosure

SEC source: 0000875320-10-000015 · edgar.xml · derivative · entry 3

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2010-05-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Right to buy under under 1996 Stock and Option Plan, fully vested on grant date, 6/1/2000.

Read SEC document
March 15, 2010 Filed Mar 16, 2010 20:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 10,000 $43.10 $431,000.00
Disclosure

SEC source: 0000875320-10-000015 · edgar.xml · nonDerivative · entry 2

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

F2 · price: Open market sales reported on this line occurred at a weighted average price of $43.10 (range $42.80 to $43.52).

F3 · price: Dr. Brimblecombe undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.

Read SEC document
March 15, 2010 Filed Mar 16, 2010 20:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 10,000 $38.44 $384,400.00
Disclosure

SEC source: 0000875320-10-000015 · edgar.xml · nonDerivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2009 Filed Jun 3, 2009 18:45 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 20,000 $0.00 Strike: $29.89 $0.00
Disclosure

SEC source: 0000875320-09-000042 · edgar.xml · derivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2019-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
June 01, 2008 Filed Jun 2, 2008 20:46 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 20,000 $0.00 Strike: $28.40 $0.00
Disclosure

SEC source: 0000875320-08-000040 · edgar.xml · derivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2018-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 3,333 $0.00 Strike: $14.20 $0.00
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · derivative · entry 11

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,333 shares

Expires 2008-05-31

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/1998.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $27.16 $9,044.28
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 10

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $26.99 $8,987.67
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 9

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 333

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 334 $26.84 $8,964.56
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 8

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 666

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $26.75 $8,907.75
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 7

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $26.71 $8,894.43
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 6

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,333

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 666 $26.68 $17,768.88
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 5

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,666

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 334 $26.66 $8,904.44
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 4

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,332

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 334 $26.54 $8,864.36
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 3

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,666

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $26.40 $8,791.20
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 2

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,000

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 27, 2008 Filed May 28, 2008 17:58 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,333 $14.20 $47,328.60
Disclosure

SEC source: 0000875320-08-000034 · edgar.xml · nonDerivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,333

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 3,333 $0.00 Strike: $14.20 $0.00
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · derivative · entry 10

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,333

Underlying: Common Stock · 3,333 shares

Expires 2008-05-31

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/1998.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $27.68 $9,217.44
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 9

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 667 $27.47 $18,322.49
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 8

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 333

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $27.73 $9,234.09
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 7

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,000

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 667 $27.71 $18,482.57
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 6

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,333

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $27.61 $9,194.13
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 5

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,000

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $27.59 $9,187.47
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 4

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,333

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 333 $27.58 $9,184.14
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 3

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,666

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 334 $27.50 $9,185.00
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 2

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,999

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved sales plan established under Rule 10b5-1.

Read SEC document
May 20, 2008 Filed May 21, 2008 19:38 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,333 $14.20 $47,328.60
Disclosure

SEC source: 0000875320-08-000028 · edgar.xml · nonDerivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,333

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 3,334 $0.00 Strike: $14.20 $0.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · derivative · entry 12

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,666

Underlying: Common Stock · 3,334 shares

Expires 2008-05-31

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/1998.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 334 $27.70 $9,251.80
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 11

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $27.46 $8,238.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 10

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 334

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $27.27 $8,181.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 9

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 634

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 500 $27.19 $13,595.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 8

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 934

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 100 $27.14 $2,714.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 7

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,434

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 200 $27.13 $5,426.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 6

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,534

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $27.08 $8,124.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 5

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,734

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $27.07 $8,121.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 4

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,034

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 300 $27.03 $8,109.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 3

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,334

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 700 $27.00 $18,900.00
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 2

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,634

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
May 13, 2008 Filed May 15, 2008 19:08 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 3,334 $14.20 $47,342.80
Disclosure

SEC source: 0000875320-08-000021 · edgar.xml · nonDerivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,334

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2007 Filed Jun 4, 2007 16:48 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 20,000 $0.00 Strike: $29.84 $0.00
Disclosure

SEC source: 0000875320-07-000062 · edgar.xml · derivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2017-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
April 10, 2007 Filed Apr 11, 2007 20:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 10,000 $0.00 Strike: $19.78 $0.00
Disclosure

SEC source: 0000875320-07-000037 · edgar.xml · derivative · entry 3

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,000 shares

Expires 2007-05-31

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/1997.

Read SEC document
April 10, 2007 Filed Apr 11, 2007 20:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 10,000 $32.36 $323,600.00
Disclosure

SEC source: 0000875320-07-000037 · edgar.xml · nonDerivative · entry 2

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Transaction made pursuant to Dr. Brimblecombe's company approved trading plan established under Rule 10b5-1.

Read SEC document
April 10, 2007 Filed Apr 11, 2007 20:18 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 10,000 $19.78 $197,800.00
Disclosure

SEC source: 0000875320-07-000037 · edgar.xml · nonDerivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 01, 2006 Filed Jun 2, 2006 17:13 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 20,000 $0.00 Strike: $34.32 $0.00
Disclosure

SEC source: 0000875320-06-000050 · edgar.xml · derivative · entry 1

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 72,500

Underlying: Common Stock · 20,000 shares

Expires 2016-05-31

F1 · derivative.exercise_date: Right to buy under 2006 Stock and Option Plan. Fully vested.

Read SEC document
February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 10,000 $0.00 Strike: $13.32 $0.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · derivative · entry 9

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,500

Underlying: Common Stock · 10,000 shares

Expires 2015-05-31

F3 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/2005.

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February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 7,500 $0.00 Strike: $9.09 $0.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · derivative · entry 8

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 62,500

Underlying: Common Stock · 7,500 shares

Expires 2014-05-31

F2 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/2004.

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February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 GrantStock Option · Derivative 10,000 $0.00 Strike: $10.05 $0.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · derivative · entry 7

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 10,000 shares

Expires 2009-05-31

F1 · derivative.exercise_date: Right to buy under 1996 Stock and Option Plan, fully vested on grant date, 6/1/1999.

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February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 10,000 $35.19 $351,900.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · nonDerivative · entry 6

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

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February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 10,000 $13.32 $133,200.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · nonDerivative · entry 5

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 SaleCommon Stock 7,500 $35.19 $263,925.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · nonDerivative · entry 4

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

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February 13, 2006 Filed Feb 14, 2006 18:53 UTC VERTEX PHARMACEUTICALS INC / MA VRTX · Entity 2875 Exercise / conversionCommon Stock 7,500 $9.09 $68,175.00
Disclosure

SEC source: 0000875320-06-000019 · edgar.xml · nonDerivative · entry 3

BRIMBLECOMBE ROGER W · CIK 0001197034 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.