organization · Reporting owner
Opaleye Management Inc.
Disclosed activity across 11 companies
Sign in to followReported relationships
Latest disclosed role at each company.
| Company | Last reported as | Report date | Published |
|---|---|---|---|
| Alpha Cognition Inc.ACOG · Entity 6339 | 10% owner | October 01, 2026 | October 03, 2026 |
| CODEXIS, INC.CDXS · Entity 6428 | 10% owner | November 26, 2025 | December 15, 2025 |
| Grace Therapeutics, Inc.GRCE · Entity 7266 | 10% owner | October 08, 2026 | October 13, 2026 |
| HARROW, INC.HROW · Entity 4740 | 10% owner | March 03, 2026 | March 05, 2026 |
| Protara Therapeutics, Inc.TARA · Entity 6203 | 10% owner | September 11, 2024 | September 13, 2024 |
| Sol-Gel Technologies Ltd.SLGL · Entity 1558 | 10% owner | September 10, 2026 | September 14, 2026 |
Disclosed balances
About these balances
Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.
Alpha Cognition Inc.
Report date October 01, 2026 · Filed October 03, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, no par valueSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 3,222,954 |
Reported balance
After 2026-10-01 transaction · row 1
Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source rowRow 1 · 2026-10-01 · Purchase · Acquired 19,050 · Balance 3,222,954 F3: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.645 to $8.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, no par valueSEC Table I · non-derivative | IndirectBy Managed Account | 100,000 |
Reported balance
Holding disclosure · report date 2026-10-01 · row 2
Holding and transaction disclosures are not merged.
1 source rowRow 2 · Balance 100,000 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F4: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.645 to $8.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
F4: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
CODEXIS, INC.
Report date November 26, 2025 · Filed December 15, 2025 · Amendment
Amendment: balances below belong to this corrected disclosure, not necessarily a complete replacement of earlier positions.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 10,305,000 |
Reported balance
After 2025-11-26 transaction · row 1
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 1 · 2025-11-26 · Sale · Disposed 148,318 · Balance 10,305,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 10,200,000 |
Reported balance
After 2025-11-28 transaction · row 3
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 3 · 2025-11-28 · Sale · Disposed 105,000 · Balance 10,200,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 9,955,000 |
Reported balance
After 2025-12-01 transaction · row 5
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 5 · 2025-12-01 · Sale · Disposed 245,000 · Balance 9,955,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 191,012 |
Reported balance
After 2025-11-26 transaction · row 2
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 2 · 2025-11-26 · Sale · Disposed 5,000 · Balance 191,012 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 188,522 |
Reported balance
After 2025-11-28 transaction · row 4
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 4 · 2025-11-28 · Sale · Disposed 2,490 · Balance 188,522 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 179,989 |
Reported balance
After 2025-12-01 transaction · row 6
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 6 · 2025-12-01 · Sale · Disposed 8,533 · Balance 179,989 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Grace Therapeutics, Inc.
Report date October 08, 2026 · Filed October 13, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.0001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 2,873,289 |
Last balance in matching sequence
After 2026-10-12 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
3 source rowsRow 1 · 2026-10-08 · Purchase · Acquired 2,077 · Balance 2,860,734 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 2 · 2026-10-09 · Purchase · Acquired 5,340 · Balance 2,866,074 F2: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.03 to $2.05. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 3 · 2026-10-12 · Purchase · Acquired 7,215 · Balance 2,873,289 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.03 to $2.05. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
HARROW, INC.
Report date March 03, 2026 · Filed March 05, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 3,622,000 |
Last balance in matching sequence
After 2026-03-04 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2026-03-03 · Sale · Disposed 59,000 · Balance 3,756,000 F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 3 · 2026-03-04 · Sale · Disposed 134,000 · Balance 3,622,000 F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 59,428 |
Last balance in matching sequence
After 2026-03-04 transaction · row 4
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 2 · 2026-03-03 · Sale · Disposed 1,309 · Balance 63,691 F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 4 · 2026-03-04 · Sale · Disposed 4,263 · Balance 59,428 F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.
F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.
F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Protara Therapeutics, Inc.
Report date September 11, 2024 · Filed September 13, 2024
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 1,944,134 |
Last balance in matching sequence
After 2024-09-12 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2024-09-11 · Sale · Disposed 31,000 · Balance 2,063,935 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.74 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. Row 3 · 2024-09-12 · Sale · Disposed 119,801 · Balance 1,944,134 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed account | 45,000 |
Last balance in matching sequence
After 2024-09-12 transaction · row 4
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 2 · 2024-09-11 · Sale · Disposed 1,600 · Balance 51,500 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.74 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. Row 4 · 2024-09-12 · Sale · Disposed 6,500 · Balance 45,000 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.74 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
Sol-Gel Technologies Ltd.
Report date September 10, 2026 · Filed September 14, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Ordinary Shares, par value NIS 1.00 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 540,000 |
Last balance in matching sequence
After 2026-09-11 transaction · row 2
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2026-09-10 · Purchase · Acquired 1,631 · Balance 538,507 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 2 · 2026-09-11 · Purchase · Acquired 1,493 · Balance 540,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Ordinary Shares, par value NIS 1.00 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 15,000 |
Reported balance
Holding disclosure · report date 2026-09-10 · row 3
Holding and transaction disclosures are not merged.
1 source rowRow 3 · Balance 15,000 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Past disclosures · reporting ended (5)
No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.
Eton Pharmaceuticals, Inc.
Report date July 14, 2026 · Filed July 17, 2026 · Amendment
Section 16 reporting ended · disclosed 2026-07-17. Current position is not established by this disclosure.
Amendment: balances below belong to this corrected disclosure, not necessarily a complete replacement of earlier positions.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 2,665,000 |
Reported balance
After 2026-07-14 transaction · row 1
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 1 · 2026-07-14 · Sale · Disposed 15,000 · Balance 2,665,000 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 40,000 |
Reported balance
After 2026-07-14 transaction · row 2
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 2 · 2026-07-14 · Sale · Disposed 13,315 · Balance 40,000 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F4: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
OCULAR THERAPEUTIX, INC
Report date April 03, 2020 · Filed April 03, 2020
Section 16 reporting ended · disclosed 2020-04-03. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.0001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 4,915,000 |
Reported balance
Holding disclosure · report date 2020-04-03 · row 1
Holding and transaction disclosures are not merged.
1 source rowRow 1 · Balance 4,915,000 F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer. F2: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. ("Opaleye") may be deemed to beneficially own the securities owned directly by the Fund. |
| Common Stock, par value $0.0001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 207,500 |
Reported balance
Holding disclosure · report date 2020-04-03 · row 2
Holding and transaction disclosures are not merged.
1 source rowRow 2 · Balance 207,500 F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer. F3: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. |
| American-style call optionSEC Table II · derivative / convertible security · Conversion / exercise price $7.50 · Expires 2020-06-19 | IndirectBy Opaleye, L.P. | 1,000 |
Reported balance
Holding disclosure · report date 2020-04-03 · row 3
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 3 · Balance 1,000 F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer. F2: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. ("Opaleye") may be deemed to beneficially own the securities owned directly by the Fund. |
Filing footnotes · ownership attribution and instrument terms
F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer.
F2: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. ("Opaleye") may be deemed to beneficially own the securities owned directly by the Fund.
F3: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
SANUWAVE Health, Inc.
Report date April 30, 2026 · Filed May 04, 2026
Section 16 reporting ended · disclosed 2026-05-04. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 853,569 |
Last balance in matching sequence
After 2026-05-01 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2026-04-30 · Sale · Disposed 24,000 · Balance 863,650 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 3 · 2026-05-01 · Sale · Disposed 10,081 · Balance 853,569 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed account | 5,000 |
Last balance in matching sequence
After 2026-05-01 transaction · row 4
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 2 · 2026-04-30 · Sale · Disposed 1,000 · Balance 5,500 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 4 · 2026-05-01 · Sale · Disposed 500 · Balance 5,000 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
TELA Bio, Inc.
Report date April 20, 2023 · Filed April 20, 2023
Section 16 reporting ended · disclosed 2023-04-20. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 124,813 |
Reported balance
Holding disclosure · report date 2023-04-20 · row 1
Holding and transaction disclosures are not merged.
1 source rowRow 1 · Balance 124,813 F1: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 1,948,000 |
Reported balance
Holding disclosure · report date 2023-04-20 · row 2
Holding and transaction disclosures are not merged.
1 source rowRow 2 · Balance 1,948,000 F2: Represents securities directly owned by Opaleye, L.P. ("the fund"). As the investment manager of the Fund, Opaleye Management may be deemed to own the securities owned directly by the Fund. |
Filing footnotes · ownership attribution and instrument terms
F1: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account.
F2: Represents securities directly owned by Opaleye, L.P. ("the fund"). As the investment manager of the Fund, Opaleye Management may be deemed to own the securities owned directly by the Fund.
Tracon Pharmaceuticals, Inc.
Report date November 10, 2023 · Filed November 14, 2023
Section 16 reporting ended · disclosed 2023-11-14. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 0 |
Reported balance
After 2023-11-10 transaction · row 1
Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source rowRow 1 · 2023-11-10 · Sale · Disposed 4,324,008 · Balance 0 F3: This transaction was executed in multiple trades at prices ranging from $0.21 to $0.375; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed account | 0 |
Reported balance
After 2023-11-10 transaction · row 2
Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source rowRow 2 · 2023-11-10 · Sale · Disposed 440,000 · Balance 0 F3: This transaction was executed in multiple trades at prices ranging from $0.21 to $0.375; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account beneficially. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2030-08-27 | IndirectBy Opaleye,L.P. | 1,667,974 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 3
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 3 · Balance 1,667,974 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2030-08-31 | IndirectBy Opaleye,L.P. | 1,358,993 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 4
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 4 · Balance 1,358,993 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2032-06-21 | IndirectBy Opaleye, L.P. | 2,205,018 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 5
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 5 · Balance 2,205,018 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2033-03-09 | IndirectBy Opaleye, L.P. | 2,013,999 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 6
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 6 · Balance 2,013,999 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account beneficially.
F3: This transaction was executed in multiple trades at prices ranging from $0.21 to $0.375; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.
F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock.
Transaction history
JSON APIPurchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Company | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| July 07, 2026 Filed Jul 7, 2026 22:29 UTC | Eton Pharmaceuticals, Inc. ETON · Entity 4598 | SaleCommon Stock, par value $0.001 per share | 6,685 | $38.37 | $256,522.17 |
DisclosureSEC source: 0001493152-26-032394 · ownership.xml · nonDerivative · entry 5 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 53,315 F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.00 to $38.565 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| July 07, 2026 Filed Jul 7, 2026 22:29 UTC | Eton Pharmaceuticals, Inc. ETON · Entity 4598 | SaleCommon Stock, par value $0.001 per share | 20,000 | $38.37 | $767,456.00 |
DisclosureSEC source: 0001493152-26-032394 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,680,000 F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.00 to $38.565 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| July 06, 2026 Filed Jul 7, 2026 22:29 UTC | Eton Pharmaceuticals, Inc. ETON · Entity 4598 | SaleCommon Stock, par value $0.001 per share | 10,000 | $38.00 | $380,000.00 |
DisclosureSEC source: 0001493152-26-032394 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,700,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| July 02, 2026 Filed Jul 2, 2026 22:11 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share | 1,400 | $71.97 | $100,758.98 |
DisclosureSEC source: 0001493152-26-031991 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 491,712 F3 · price: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $71.96-$71.99 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| July 02, 2026 Filed Jul 7, 2026 22:29 UTC | Eton Pharmaceuticals, Inc. ETON · Entity 4598 | SaleCommon Stock, par value $0.001 per share | 25,000 | $37.39 | $934,627.50 |
DisclosureSEC source: 0001493152-26-032394 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 60,000 F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.05 to $37.85 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| July 02, 2026 Filed Jul 7, 2026 22:29 UTC | Eton Pharmaceuticals, Inc. ETON · Entity 4598 | SaleCommon Stock, par value $0.001 per share | 65,000 | $37.39 | $2,430,031.50 |
DisclosureSEC source: 0001493152-26-032394 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,710,000 F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.05 to $37.85 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| July 01, 2026 Filed Jul 2, 2026 22:11 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share | 312 | $71.99 | $22,460.88 |
DisclosureSEC source: 0001493152-26-031991 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 490,312 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 26, 2026 Filed Jun 29, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 152,336 | $6.40 | $975,209.37 |
DisclosureSEC source: 0001493152-26-031063 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,805,107 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.335 to $6.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 25, 2026 Filed Jun 29, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 197 | $6.50 | $1,280.50 |
DisclosureSEC source: 0001493152-26-031063 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,652,771 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 15, 2026 Filed Jun 16, 2026 00:10 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 4,550 | $5.99 | $27,252.68 |
DisclosureSEC source: 0001493152-26-028783 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,652,574 F5 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.97 to $5.9896. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 12, 2026 Filed Jun 16, 2026 00:10 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 273 | $5.93 | $1,619.46 |
DisclosureSEC source: 0001493152-26-028783 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,648,024 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.9275 to $5.94. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 11, 2026 Filed Jun 16, 2026 00:10 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 2,862 | $5.91 | $16,900.97 |
DisclosureSEC source: 0001493152-26-028783 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,647,751 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.87 to $5.91. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 10, 2026 Filed Jun 11, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 5,872 | $5.99 | $35,157.43 |
DisclosureSEC source: 0001493152-26-028276 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,644,889 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.925 to $5.99. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 09, 2026 Filed Jun 11, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 24,856 | $5.98 | $148,534.48 |
DisclosureSEC source: 0001493152-26-028276 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,639,017 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.9465 to $5.99. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| June 05, 2026 Filed Jun 9, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 10,054 | $5.83 | $58,595.72 |
DisclosureSEC source: 0001493152-26-027927 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,614,161 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.82 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 29, 2026 Filed May 29, 2026 23:21 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 70,577 | $5.90 | $416,397.24 |
DisclosureSEC source: 0001493152-26-026472 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,604,107 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.88 to $5.90. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 28, 2026 Filed May 29, 2026 23:21 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 2,000 | $5.83 | $11,664.00 |
DisclosureSEC source: 0001493152-26-026472 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,533,530 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.82 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 27, 2026 Filed May 29, 2026 23:21 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 1,161 | $5.73 | $6,652.53 |
DisclosureSEC source: 0001493152-26-026472 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,531,530 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 21, 2026 Filed May 22, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 15,945 | $5.70 | $90,886.50 |
DisclosureSEC source: 0001493152-26-025011 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,530,369 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 20, 2026 Filed May 22, 2026 20:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 1,563 | $64.43 | $100,711.75 |
DisclosureSEC source: 0001493152-26-025013 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 490,000 F3 · price: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $63.97-$64.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 20, 2026 Filed May 22, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 8,431 | $5.89 | $49,658.59 |
DisclosureSEC source: 0001493152-26-025011 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,514,424 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 18, 2026 Filed May 19, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 17,395 | $5.69 | $99,022.78 |
DisclosureSEC source: 0001493152-26-024411 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,505,993 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.60 to $5.87. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 15, 2026 Filed May 19, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 16,648 | $5.83 | $96,986.25 |
DisclosureSEC source: 0001493152-26-024411 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,488,598 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.75 to $5.83. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 13, 2026 Filed May 14, 2026 20:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 1,937 | $66.87 | $129,527.38 |
DisclosureSEC source: 0001493152-26-023056 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 488,437 F4 · price: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $66.00-$67.3820 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 12, 2026 Filed May 14, 2026 20:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 1,500 | $67.98 | $101,974.95 |
DisclosureSEC source: 0001493152-26-023056 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 486,500 F3 · price: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $67.95-$68.00 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 01, 2026 Filed May 4, 2026 20:05 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 500 | $16.11 | $8,055.25 |
DisclosureSEC source: 0001493152-26-021104 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed account Disclosed balance after: 5,000 F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| May 01, 2026 Filed May 4, 2026 20:05 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 10,081 | $16.11 | $162,409.95 |
DisclosureSEC source: 0001493152-26-021104 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 853,569 F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 30, 2026 Filed May 4, 2026 20:05 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 1,000 | $16.15 | $16,151.00 |
DisclosureSEC source: 0001493152-26-021104 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed account Disclosed balance after: 5,500 F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 30, 2026 Filed May 4, 2026 20:05 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 24,000 | $16.15 | $387,624.00 |
DisclosureSEC source: 0001493152-26-021104 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 863,650 F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 29, 2026 Filed Apr 30, 2026 20:10 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 1,000 | $17.25 | $17,247.60 |
DisclosureSEC source: 0001493152-26-020494 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed account Disclosed balance after: 6,500 F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.58-$17.51 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 29, 2026 Filed Apr 30, 2026 20:10 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 23,360 | $17.25 | $402,903.94 |
DisclosureSEC source: 0001493152-26-020494 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 887,650 F4 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.58-$17.51 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 28, 2026 Filed Apr 30, 2026 20:10 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 2,500 | $18.47 | $46,168.50 |
DisclosureSEC source: 0001493152-26-020494 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed account Disclosed balance after: 7,500 F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $18.41-$18.6615 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 28, 2026 Filed Apr 30, 2026 20:10 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 43,788 | $18.47 | $808,650.51 |
DisclosureSEC source: 0001493152-26-020494 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 911,010 F3 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $18.41-$18.6615 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 21, 2026 Filed Apr 21, 2026 22:17 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 202 | $20.50 | $4,141.51 |
DisclosureSEC source: 0001493152-26-018387 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 954,798 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 17, 2026 Filed Apr 21, 2026 22:17 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 5,000 | $20.46 | $102,305.50 |
DisclosureSEC source: 0001493152-26-018387 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed account Disclosed balance after: 10,000 F3 · price: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $20.17-$21.00 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| April 17, 2026 Filed Apr 21, 2026 22:17 UTC | SANUWAVE Health, Inc. SNWV · Entity 7321 | SaleCommon Stock, par value $0.001 per share | 11,267 | $20.46 | $230,535.21 |
DisclosureSEC source: 0001493152-26-018387 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 955,000 F3 · price: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $20.17-$21.00 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 30, 2026 Filed Mar 31, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 1,850 | $4.99 | $9,226.51 |
DisclosureSEC source: 0001493152-26-014123 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,471,850 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 27, 2026 Filed Mar 31, 2026 20:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 10,000 | $5.08 | $50,792.00 |
DisclosureSEC source: 0001493152-26-014123 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,470,000 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.0674 to $5.0909. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 26, 2026 Filed Mar 26, 2026 22:57 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 7,319 | $5.28 | $38,675.06 |
DisclosureSEC source: 0001493152-26-013022 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,460,000 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.159 to $5.3243. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 25, 2026 Filed Mar 26, 2026 22:57 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 8,581 | $5.43 | $46,578.53 |
DisclosureSEC source: 0001493152-26-013022 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,452,681 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.39 to $5.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 24, 2026 Filed Mar 24, 2026 20:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 5,000 | $72.00 | $360,000.00 |
DisclosureSEC source: 0001493152-26-012354 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 15,000 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F3 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 24, 2026 Filed Mar 24, 2026 20:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 34,665 | $72.00 | $2,495,880.00 |
DisclosureSEC source: 0001493152-26-012354 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 485,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 24, 2026 Filed Mar 26, 2026 22:57 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 4,182 | $5.59 | $23,377.38 |
DisclosureSEC source: 0001493152-26-013022 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,444,100 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 19, 2026 Filed Mar 20, 2026 20:54 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 2,094 | $5.71 | $11,950.46 |
DisclosureSEC source: 0001493152-26-011902 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,439,918 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.699 to $5.75. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 18, 2026 Filed Mar 20, 2026 20:54 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 2,481 | $5.75 | $14,263.27 |
DisclosureSEC source: 0001493152-26-011902 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,437,824 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.749 to $5.75. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 16, 2026 Filed Mar 18, 2026 22:55 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 1,331 | $5.78 | $7,695.84 |
DisclosureSEC source: 0001493152-26-011391 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,435,343 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.76 to $5.79. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 13, 2026 Filed Mar 13, 2026 22:43 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 7,358 | $5.75 | $42,286.43 |
DisclosureSEC source: 0001493152-26-010130 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,434,012 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.696 to $5.75. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 12, 2026 Filed Mar 13, 2026 22:43 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 5,708 | $5.85 | $33,416.34 |
DisclosureSEC source: 0001493152-26-010130 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,426,654 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.84 to $5.859. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 09, 2026 Filed Mar 10, 2026 22:47 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 2,179 | $5.85 | $12,742.14 |
DisclosureSEC source: 0001493152-26-009591 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,420,946 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.785 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 06, 2026 Filed Mar 10, 2026 22:47 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 1,900 | $5.80 | $11,017.91 |
DisclosureSEC source: 0001493152-26-009591 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,418,767 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.70 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.