organization · Reporting owner
Opaleye Management Inc.
Disclosed activity across 11 companies
Sign in to followReported relationships
Latest disclosed role at each company.
| Company | Last reported as | Report date | Published |
|---|---|---|---|
| Alpha Cognition Inc.ACOG · Entity 6339 | 10% owner | October 01, 2026 | October 03, 2026 |
| CODEXIS, INC.CDXS · Entity 6428 | 10% owner | November 26, 2025 | December 15, 2025 |
| Grace Therapeutics, Inc.GRCE · Entity 7266 | 10% owner | October 08, 2026 | October 13, 2026 |
| HARROW, INC.HROW · Entity 4740 | 10% owner | March 03, 2026 | March 05, 2026 |
| Protara Therapeutics, Inc.TARA · Entity 6203 | 10% owner | September 11, 2024 | September 13, 2024 |
| Sol-Gel Technologies Ltd.SLGL · Entity 1558 | 10% owner | September 10, 2026 | September 14, 2026 |
Disclosed balances
About these balances
Latest available filing per company, not a reconstructed current portfolio. Matching sequences show the last reported balance with all source rows expandable; grouping alone does not establish account ownership. Do not add unresolved positions together. Filings may omit unchanged positions, and amendments may correct only part of an older disclosure. Jointly reported shares are not necessarily this owner's personal holdings.
Alpha Cognition Inc.
Report date October 01, 2026 · Filed October 03, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, no par valueSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 3,222,954 |
Reported balance
After 2026-10-01 transaction · row 1
Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source rowRow 1 · 2026-10-01 · Purchase · Acquired 19,050 · Balance 3,222,954 F3: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.645 to $8.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, no par valueSEC Table I · non-derivative | IndirectBy Managed Account | 100,000 |
Reported balance
Holding disclosure · report date 2026-10-01 · row 2
Holding and transaction disclosures are not merged.
1 source rowRow 2 · Balance 100,000 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F4: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.645 to $8.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
F4: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
CODEXIS, INC.
Report date November 26, 2025 · Filed December 15, 2025 · Amendment
Amendment: balances below belong to this corrected disclosure, not necessarily a complete replacement of earlier positions.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 10,305,000 |
Reported balance
After 2025-11-26 transaction · row 1
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 1 · 2025-11-26 · Sale · Disposed 148,318 · Balance 10,305,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 10,200,000 |
Reported balance
After 2025-11-28 transaction · row 3
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 3 · 2025-11-28 · Sale · Disposed 105,000 · Balance 10,200,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 9,955,000 |
Reported balance
After 2025-12-01 transaction · row 5
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 5 · 2025-12-01 · Sale · Disposed 245,000 · Balance 9,955,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 191,012 |
Reported balance
After 2025-11-26 transaction · row 2
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 2 · 2025-11-26 · Sale · Disposed 5,000 · Balance 191,012 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 188,522 |
Reported balance
After 2025-11-28 transaction · row 4
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 4 · 2025-11-28 · Sale · Disposed 2,490 · Balance 188,522 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 179,989 |
Reported balance
After 2025-12-01 transaction · row 6
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 6 · 2025-12-01 · Sale · Disposed 8,533 · Balance 179,989 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F6: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Grace Therapeutics, Inc.
Report date October 08, 2026 · Filed October 13, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.0001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 2,873,289 |
Last balance in matching sequence
After 2026-10-12 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
3 source rowsRow 1 · 2026-10-08 · Purchase · Acquired 2,077 · Balance 2,860,734 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 2 · 2026-10-09 · Purchase · Acquired 5,340 · Balance 2,866,074 F2: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.03 to $2.05. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 3 · 2026-10-12 · Purchase · Acquired 7,215 · Balance 2,873,289 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.03 to $2.05. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
HARROW, INC.
Report date March 03, 2026 · Filed March 05, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 3,622,000 |
Last balance in matching sequence
After 2026-03-04 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2026-03-03 · Sale · Disposed 59,000 · Balance 3,756,000 F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 3 · 2026-03-04 · Sale · Disposed 134,000 · Balance 3,622,000 F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 59,428 |
Last balance in matching sequence
After 2026-03-04 transaction · row 4
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 2 · 2026-03-03 · Sale · Disposed 1,309 · Balance 63,691 F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 4 · 2026-03-04 · Sale · Disposed 4,263 · Balance 59,428 F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.
F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.
F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Protara Therapeutics, Inc.
Report date September 11, 2024 · Filed September 13, 2024
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 1,944,134 |
Last balance in matching sequence
After 2024-09-12 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2024-09-11 · Sale · Disposed 31,000 · Balance 2,063,935 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.74 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. Row 3 · 2024-09-12 · Sale · Disposed 119,801 · Balance 1,944,134 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed account | 45,000 |
Last balance in matching sequence
After 2024-09-12 transaction · row 4
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 2 · 2024-09-11 · Sale · Disposed 1,600 · Balance 51,500 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.74 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. Row 4 · 2024-09-12 · Sale · Disposed 6,500 · Balance 45,000 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.74 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70-$1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
Sol-Gel Technologies Ltd.
Report date September 10, 2026 · Filed September 14, 2026
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Ordinary Shares, par value NIS 1.00 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 540,000 |
Last balance in matching sequence
After 2026-09-11 transaction · row 2
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2026-09-10 · Purchase · Acquired 1,631 · Balance 538,507 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 2 · 2026-09-11 · Purchase · Acquired 1,493 · Balance 540,000 F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Ordinary Shares, par value NIS 1.00 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 15,000 |
Reported balance
Holding disclosure · report date 2026-09-10 · row 3
Holding and transaction disclosures are not merged.
1 source rowRow 3 · Balance 15,000 F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Past disclosures · reporting ended (5)
No longer tracked through insider filings. These historical balances do not imply present ownership or a zero position.
Eton Pharmaceuticals, Inc.
Report date July 14, 2026 · Filed July 17, 2026 · Amendment
Section 16 reporting ended · disclosed 2026-07-17. Current position is not established by this disclosure.
Amendment: balances below belong to this corrected disclosure, not necessarily a complete replacement of earlier positions.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 2,665,000 |
Reported balance
After 2026-07-14 transaction · row 1
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 1 · 2026-07-14 · Sale · Disposed 15,000 · Balance 2,665,000 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 40,000 |
Reported balance
After 2026-07-14 transaction · row 2
Amendment: may correct only part of an earlier disclosure.
1 source rowRow 2 · 2026-07-14 · Sale · Disposed 13,315 · Balance 40,000 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. F4: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $37.0152 to $37.9148 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
OCULAR THERAPEUTIX, INC
Report date April 03, 2020 · Filed April 03, 2020
Section 16 reporting ended · disclosed 2020-04-03. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.0001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 4,915,000 |
Reported balance
Holding disclosure · report date 2020-04-03 · row 1
Holding and transaction disclosures are not merged.
1 source rowRow 1 · Balance 4,915,000 F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer. F2: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. ("Opaleye") may be deemed to beneficially own the securities owned directly by the Fund. |
| Common Stock, par value $0.0001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 207,500 |
Reported balance
Holding disclosure · report date 2020-04-03 · row 2
Holding and transaction disclosures are not merged.
1 source rowRow 2 · Balance 207,500 F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer. F3: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. |
| American-style call optionSEC Table II · derivative / convertible security · Conversion / exercise price $7.50 · Expires 2020-06-19 | IndirectBy Opaleye, L.P. | 1,000 |
Reported balance
Holding disclosure · report date 2020-04-03 · row 3
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 3 · Balance 1,000 F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer. F2: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. ("Opaleye") may be deemed to beneficially own the securities owned directly by the Fund. |
Filing footnotes · ownership attribution and instrument terms
F1: No transactions are being reported in connection with this Form 4. The stock ownership listed was previously reported on a Form 3, Form 4 and Schedule 13G/A filed with the SEC. Based on the total number of shares of common stock reported issued and outstanding by the Issuer in its annual report on Form 10-K, filed with the SEC on March 12, 2020, the Reporting Person no longer owns in excess of 10% of the Issuer's common stock, and this Form 4 is being filed solely to reflect that the Reporting Person is no longer subject to Section 16 reporting obligations in connection with its holdings of the Issuer.
F2: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. ("Opaleye") may be deemed to beneficially own the securities owned directly by the Fund.
F3: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
SANUWAVE Health, Inc.
Report date April 30, 2026 · Filed May 04, 2026
Section 16 reporting ended · disclosed 2026-05-04. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 853,569 |
Last balance in matching sequence
After 2026-05-01 transaction · row 3
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 1 · 2026-04-30 · Sale · Disposed 24,000 · Balance 863,650 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 3 · 2026-05-01 · Sale · Disposed 10,081 · Balance 853,569 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed account | 5,000 |
Last balance in matching sequence
After 2026-05-01 transaction · row 4
Source-order balances reconcile. Account continuity and personal attribution are not independently verified.
2 source rowsRow 2 · 2026-04-30 · Sale · Disposed 1,000 · Balance 5,500 F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Row 4 · 2026-05-01 · Sale · Disposed 500 · Balance 5,000 F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.10-$16.775 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $16.00-$16.28 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price.
F5: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
TELA Bio, Inc.
Report date April 20, 2023 · Filed April 20, 2023
Section 16 reporting ended · disclosed 2023-04-20. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed Account | 124,813 |
Reported balance
Holding disclosure · report date 2023-04-20 · row 1
Holding and transaction disclosures are not merged.
1 source rowRow 1 · Balance 124,813 F1: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 1,948,000 |
Reported balance
Holding disclosure · report date 2023-04-20 · row 2
Holding and transaction disclosures are not merged.
1 source rowRow 2 · Balance 1,948,000 F2: Represents securities directly owned by Opaleye, L.P. ("the fund"). As the investment manager of the Fund, Opaleye Management may be deemed to own the securities owned directly by the Fund. |
Filing footnotes · ownership attribution and instrument terms
F1: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account.
F2: Represents securities directly owned by Opaleye, L.P. ("the fund"). As the investment manager of the Fund, Opaleye Management may be deemed to own the securities owned directly by the Fund.
Tracon Pharmaceuticals, Inc.
Report date November 10, 2023 · Filed November 14, 2023
Section 16 reporting ended · disclosed 2023-11-14. Current position is not established by this disclosure.
| Security / award | Ownership account | Disclosed shares / units | Disclosure context |
|---|---|---|---|
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Opaleye, L.P. | 0 |
Reported balance
After 2023-11-10 transaction · row 1
Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source rowRow 1 · 2023-11-10 · Sale · Disposed 4,324,008 · Balance 0 F3: This transaction was executed in multiple trades at prices ranging from $0.21 to $0.375; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Common Stock, par value $0.001 per shareSEC Table I · non-derivative | IndirectBy Managed account | 0 |
Reported balance
After 2023-11-10 transaction · row 2
Account identity is unresolved; indirect or unspecified ownership is not merged.
1 source rowRow 2 · 2023-11-10 · Sale · Disposed 440,000 · Balance 0 F3: This transaction was executed in multiple trades at prices ranging from $0.21 to $0.375; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased. F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account beneficially. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2030-08-27 | IndirectBy Opaleye,L.P. | 1,667,974 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 3
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 3 · Balance 1,667,974 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2030-08-31 | IndirectBy Opaleye,L.P. | 1,358,993 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 4
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 4 · Balance 1,358,993 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2032-06-21 | IndirectBy Opaleye, L.P. | 2,205,018 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 5
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 5 · Balance 2,205,018 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
| Prefunded WarrantsSEC Table II · derivative / convertible security · Conversion / exercise price $0.01 · Expires 2033-03-09 | IndirectBy Opaleye, L.P. | 2,013,999 |
Reported balance
Holding disclosure · report date 2023-11-10 · row 6
Instrument identity requires review; Table II rows are not merged.
1 source rowRow 6 · Balance 2,013,999 F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock. F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund. |
Filing footnotes · ownership attribution and instrument terms
F1: Represents securities owned directly by Opaleye, L.P. (The "Fund"). As the investment manager of the Fund.
F2: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to own the securities owned directly by the Managed Account beneficially.
F3: This transaction was executed in multiple trades at prices ranging from $0.21 to $0.375; the price reported above reflects the weighted average purchase price. The reporting person undertakes to provide upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased.
F4: The warrants may not be exercised to the extent that such exercise would cause the reporting person and its affiliates to beneficially own more than 19.99% of the Issuer's then outstanding common stock.
Transaction history
JSON APIPurchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Company | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| March 05, 2026 Filed Mar 6, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 5,000 | $5.80 | $28,988.00 |
DisclosureSEC source: 0001493152-26-009136 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 90,000 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.70 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 05, 2026 Filed Mar 6, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 42,023 | $5.80 | $243,632.54 |
DisclosureSEC source: 0001493152-26-009136 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,416,867 F4 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.70 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 04, 2026 Filed Mar 5, 2026 21:05 UTC | HARROW, INC. HROW · Entity 4740 | SaleCommon Stock, par value $0.001 per share | 4,263 | $39.67 | $169,122.16 |
DisclosureSEC source: 0001493152-26-008990 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 59,428 F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 04, 2026 Filed Mar 5, 2026 21:05 UTC | HARROW, INC. HROW · Entity 4740 | SaleCommon Stock, par value $0.001 per share | 134,000 | $39.67 | $5,316,061.40 |
DisclosureSEC source: 0001493152-26-008990 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 3,622,000 F4 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 04, 2026 Filed Mar 6, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 19,795 | $5.81 | $115,001.03 |
DisclosureSEC source: 0001493152-26-009136 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,374,844 F3 · price: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.72 to $5.8689. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 03, 2026 Filed Mar 4, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 5,000 | $5.75 | $28,751.00 |
DisclosureSEC source: 0001493152-26-008846 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 85,000 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.41 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 03, 2026 Filed Mar 4, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 46,411 | $5.75 | $266,872.53 |
DisclosureSEC source: 0001493152-26-008846 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,355,049 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.41 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 03, 2026 Filed Mar 5, 2026 21:05 UTC | HARROW, INC. HROW · Entity 4740 | SaleCommon Stock, par value $0.001 per share | 1,309 | $39.15 | $51,250.49 |
DisclosureSEC source: 0001493152-26-008990 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 63,691 F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 03, 2026 Filed Mar 5, 2026 21:05 UTC | HARROW, INC. HROW · Entity 4740 | SaleCommon Stock, par value $0.001 per share | 59,000 | $39.15 | $2,309,991.60 |
DisclosureSEC source: 0001493152-26-008990 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 3,756,000 F3 · price: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| March 02, 2026 Filed Mar 4, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 20,000 | $5.80 | $116,000.00 |
DisclosureSEC source: 0001493152-26-008846 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,308,638 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 27, 2026 Filed Mar 2, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 3,638 | $5.99 | $21,797.08 |
DisclosureSEC source: 0001493152-26-008538 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,288,638 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.975 to $6.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 27, 2026 Filed Mar 3, 2026 21:05 UTC | HARROW, INC. HROW · Entity 4740 | SaleCommon Stock, par value $0.001 per share | 5,000 | $54.18 | $270,900.00 |
DisclosureSEC source: 0001493152-26-008708 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 65,000 F1 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 26, 2026 Filed Mar 2, 2026 21:05 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 590 | $5.99 | $3,531.15 |
DisclosureSEC source: 0001493152-26-008538 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,285,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.975 to $6.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 24, 2026 Filed Feb 24, 2026 22:52 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 5,000 | $5.80 | $29,002.00 |
DisclosureSEC source: 0001493152-26-007920 · ownership.xml · nonDerivative · entry 6 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 80,000 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.615 to $5.95. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 24, 2026 Filed Feb 24, 2026 22:52 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 53,591 | $5.80 | $310,849.24 |
DisclosureSEC source: 0001493152-26-007920 · ownership.xml · nonDerivative · entry 5 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,284,410 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.615 to $5.95. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 23, 2026 Filed Feb 24, 2026 22:52 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 4,181 | $5.89 | $24,635.71 |
DisclosureSEC source: 0001493152-26-007920 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 75,000 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F4 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.59 to $5.99. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 23, 2026 Filed Feb 24, 2026 22:52 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 95,819 | $5.89 | $564,594.29 |
DisclosureSEC source: 0001493152-26-007920 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,230,819 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.59 to $5.99. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 20, 2026 Filed Feb 24, 2026 22:52 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 2,819 | $5.84 | $16,466.06 |
DisclosureSEC source: 0001493152-26-007920 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 70,819 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.75 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 20, 2026 Filed Feb 24, 2026 22:52 UTC | Alpha Cognition Inc. ACOG · Entity 6339 | PurchaseCommon Stock, no par value | 10,000 | $5.84 | $58,411.00 |
DisclosureSEC source: 0001493152-26-007920 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 2,135,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.75 to $5.85. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 13, 2026 Filed Feb 18, 2026 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 291 | $63.00 | $18,333.00 |
DisclosureSEC source: 0001493152-26-007330 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 450,335 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 02, 2026 Filed Feb 4, 2026 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 100 | $58.00 | $5,800.00 |
DisclosureSEC source: 0001493152-26-005094 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 450,944 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| February 02, 2026 Filed Feb 18, 2026 17:59 UTC Amendment | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 100 | $58.00 | $5,800.00 |
DisclosureSEC source: 0001493152-26-007306 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 450,044 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: This amendment corrects the number of shares reported as beneficially owned due to a clerical error. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| January 27, 2026 Filed Jan 29, 2026 21:16 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 100 | $57.05 | $5,705.00 |
DisclosureSEC source: 0001493152-26-004234 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 449,944 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| January 23, 2026 Filed Jan 23, 2026 22:42 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 1,151 | $55.98 | $64,434.02 |
DisclosureSEC source: 0001493152-26-003468 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 449,844 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $56.00 to $57.00. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range. F4 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $52.66 to $57.00. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| January 22, 2026 Filed Jan 23, 2026 22:42 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 2,173 | $56.57 | $122,922.48 |
DisclosureSEC source: 0001493152-26-003468 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 448,693 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $56.00 to $57.00. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| January 06, 2026 Filed Jan 8, 2026 21:05 UTC | HARROW, INC. HROW · Entity 4740 | SaleCommon Stock, par value $0.001 per share | 20,000 | $53.35 | $1,066,914.00 |
DisclosureSEC source: 0001493152-26-000965 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 70,000 F1 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $53.00 - $53.93 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| January 05, 2026 Filed Jan 6, 2026 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 198 | $42.98 | $8,510.04 |
DisclosureSEC source: 0001493152-26-000588 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 447,331 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| January 02, 2026 Filed Jan 6, 2026 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 2,394 | $41.92 | $100,347.86 |
DisclosureSEC source: 0001493152-26-000588 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 447,133 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $41.68 to $42.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 31, 2025 Filed Dec 31, 2025 22:45 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 22,497 | $41.99 | $944,743.52 |
DisclosureSEC source: 0001493152-25-029866 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 443,739 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $39.95 to $42.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 30, 2025 Filed Dec 31, 2025 22:45 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 35,169 | $41.99 | $1,476,626.74 |
DisclosureSEC source: 0001493152-25-029866 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 421,242 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $41.8008 to $42.00. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 29, 2025 Filed Dec 31, 2025 22:45 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 8,638 | $41.85 | $361,533.99 |
DisclosureSEC source: 0001493152-25-029866 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 386,073 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $41.5391 to $41.99. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 26, 2025 Filed Dec 29, 2025 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 1,626 | $41.68 | $67,764.53 |
DisclosureSEC source: 0001493152-25-029359 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 377,435 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $41.6266 to $41.75. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 23, 2025 Filed Dec 29, 2025 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 260 | $41.66 | $10,832.46 |
DisclosureSEC source: 0001493152-25-029359 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 375,809 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $41.35 to $41.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 22, 2025 Filed Dec 29, 2025 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 1,019 | $41.15 | $41,935.62 |
DisclosureSEC source: 0001493152-25-029359 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 375,549 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $40.985 to $41.70. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 17, 2025 Filed Dec 19, 2025 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 2,735 | $40.37 | $110,412.22 |
DisclosureSEC source: 0001493152-25-028550 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 374,530 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $38.00 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 12, 2025 Filed Dec 16, 2025 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 87 | $40.00 | $3,480.00 |
DisclosureSEC source: 0001493152-25-027959 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 371,795 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 08, 2025 Filed Dec 9, 2025 21:12 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 300 | $39.78 | $11,932.50 |
DisclosureSEC source: 0001493152-25-026848 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 371,708 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 05, 2025 Filed Dec 9, 2025 21:12 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 444 | $39.50 | $17,536.80 |
DisclosureSEC source: 0001493152-25-026848 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 371,408 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $38,90 - $39.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 03, 2025 Filed Dec 3, 2025 22:39 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 2,524 | $37.81 | $95,443.04 |
DisclosureSEC source: 0001493152-25-026021 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 370,964 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $37.40 - $37.90 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 01, 2025 Filed Dec 1, 2025 22:41 UTC | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 8,533 | $1.67 | $14,228.78 |
DisclosureSEC source: 0001493152-25-025624 · ownership.xml · nonDerivative · entry 6 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 179,989 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 01, 2025 Filed Dec 1, 2025 22:41 UTC | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 245,000 | $1.67 | $408,537.50 |
DisclosureSEC source: 0001493152-25-025624 · ownership.xml · nonDerivative · entry 5 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 9,955,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 01, 2025 Filed Dec 3, 2025 22:39 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 4,340 | $37.37 | $162,166.70 |
DisclosureSEC source: 0001493152-25-026021 · ownership.xml · nonDerivative · entry 1 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 368,440 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $36.945 - $37.95 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F5 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 01, 2025 Filed Dec 15, 2025 11:06 UTC Amendment | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 8,533 | $1.67 | $14,228.78 |
DisclosureSEC source: 0001493152-25-027633 · ownership.xml · nonDerivative · entry 6 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 179,989 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F5 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| December 01, 2025 Filed Dec 15, 2025 11:06 UTC Amendment | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 245,000 | $1.67 | $408,537.50 |
DisclosureSEC source: 0001493152-25-027633 · ownership.xml · nonDerivative · entry 5 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 9,955,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F5 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| November 28, 2025 Filed Dec 1, 2025 22:41 UTC | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 2,490 | $1.75 | $4,357.50 |
DisclosureSEC source: 0001493152-25-025624 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 188,522 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F4 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| November 28, 2025 Filed Dec 1, 2025 22:41 UTC | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 105,000 | $1.75 | $183,750.00 |
DisclosureSEC source: 0001493152-25-025624 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 10,200,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| November 28, 2025 Filed Dec 15, 2025 11:06 UTC Amendment | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 2,490 | $1.75 | $4,357.50 |
DisclosureSEC source: 0001493152-25-027633 · ownership.xml · nonDerivative · entry 4 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 188,522 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F4 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| November 28, 2025 Filed Dec 15, 2025 11:06 UTC Amendment | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 105,000 | $1.75 | $183,750.00 |
DisclosureSEC source: 0001493152-25-027633 · ownership.xml · nonDerivative · entry 3 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 10,200,000 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F4 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| November 26, 2025 Filed Nov 26, 2025 21:05 UTC | Sol-Gel Technologies Ltd. SLGL · Entity 1558 | PurchaseOrdinary Shares, par value NIS 1.00 per share. | 943 | $40.00 | $37,720.00 |
DisclosureSEC source: 0001493152-25-025138 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Opaleye, L.P. Disclosed balance after: 364,100 F1 · ownership.nature: Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. F3 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $39.99 - $40.00 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F4 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
| November 26, 2025 Filed Dec 1, 2025 22:41 UTC | CODEXIS, INC. CDXS · Entity 6428 | SaleCommon Stock, par value $0.001 per share | 5,000 | $1.74 | $8,706.50 |
DisclosureSEC source: 0001493152-25-025624 · ownership.xml · nonDerivative · entry 2 Opaleye Management Inc. · CIK 0001595855 · 10% owner 10b5-1 filing: No plan indicated Ownership: Indirect · By Managed Account Disclosed balance after: 191,012 F2 · ownership.nature: Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. F3 · ownership.nature: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price. F6 · ownership.nature: Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.